1.Comparison of between Efficacy of Intravaginal Misoprostol and Intravenous Sulprostone in Termination of Second Trimester Pregnancy.
Korean Journal of Perinatology 1998;9(3):299-303
To compare the efficiency, success rate and abortion time of applications of intravaginal misoprostol versus intravenous Sulprostone(Nalador) for mid-trimester pregnancy termination. Eighty three patients between 17-29 weeks of gestation with medical, obstetric, or genetic reasons for termination of pregnancy were randomized to receive either 50 ug tablets of misoprostol placed in the posterior vaginal fomix or 1,000ug sulprostone intravenously diluted I L of isotonic saline solution given as a 12-h infusion. Among eighty three patients recruited, fourty five patients received misoprostol and thirty eight patients received sulprostone intravenously. The average interval from start of induction to vaginal delivery was 13.35+/-3.34 hours in misoprostol group and 21.14+/-6.64 hours in the sulprostone group. The success rate of complete termination within 12 and 24 hours in misoprostol group were 57.7%, 93.3%, respectively, while in sulprostone group were 15.8%, 92.1% respectively. Oxytocin augumentation was 6.7% in misoprostol group and 7.9% in the sulprostone group. No serious complication occurred. Intravaginal misoprostol appears to be acceptably safe and effective agents for second trimester pregnancy termination. Misoprostol has the advantage of being inexpensive, easily stored and readily available. The regimen of 100 ug misoprostol inserted intracervicovaginally every 8 hours is the optimal method for pregnancy termination.
Female
;
Humans
;
Misoprostol*
;
Oxytocin
;
Pregnancy
;
Pregnancy Trimester, Second*
;
Sodium Chloride
;
Tablets
2.Comparison of Placental Apoptosis in Normal Pregnancy, Preeclampsia and Intrauterine Growth Restriction.
Korean Journal of Obstetrics and Gynecology 2002;45(6):951-959
OBJECTIVE: Aims of this study were to conclusively demonstrate apoptosis in the human placenta and to compare of placental apoptosis in normal pregnancy, preeclampsia and intrauterine growth restriction. METHODS: Placental samples obtained from 30 term, normal pregnancy, 30 pregnancies complicated intrauterine growth restriction, 30 pregnancies complicated preclampsia. The definition used to identify intrauterine growth restriction depends on fetal body weight ratio less than 10 percentile by ultrasonography. The definition used to identify preeclampsia depend on ACOG criteria. Light microscopy and polyclonal antibodies of Fas, Fas ligand, Bax, Bcl-2 were used to identify apoptosis. RESULTS: Apoptosis was conclusively demonstrated within placental tissue. Results of immunohis-tochemical analysis of Fas in the trophoblast of normal pregnancy, pregnancy induced hypertension and intrauterine growth restriction were negative of 86.7%, 26.7% and 13.3% respectively. Results of immunohistochemical analysis of Fas lgand in the trophoblast of normal pregnancy, pregnancy induced hypertension and intrauterine growth restriction were diffuse positive of 53.3%, 16.7% and 6.7% respectively. Results of immunohistochemical analysis of Bcl-2 in the trophoblast of normal pregnancy, pregnancy induced hypertension and intrauterine growth restriction were diffusely positive of 90.0%, 76.7% and 66.7% respectively. Results of immunohistochemical analysis of Bax in the trophoblast of normal pregnancy, preeclampsia and intrauterine growth restriction were diffuse positive of 40.0%, 40.0% and 50.0% respectively. CONCLUSION: Apoptosis and altered expression of Bcl-2 in trophoblast were conclusively demonstrated within placental tissue, suggesting that it may play a role in the normal development and aging of the placenta. Placental apoptosis and altered expression of Fas and Fas ligand in trophoblast might influence pathogenesis or pathophysiologic mechanism of preeclamsia and intrauterine growth restriction.
Aging
;
Antibodies
;
Apoptosis*
;
Fas Ligand Protein
;
Female
;
Fetal Weight
;
Humans
;
Hypertension, Pregnancy-Induced
;
Microscopy
;
Placenta
;
Pre-Eclampsia*
;
Pregnancy*
;
Trophoblasts
;
Ultrasonography
3.Preservation of quadriceps function in limb salvage operation forosteosarcoma of proximal tibia: report of 2 cases.
Jung Man KIM ; Yong Sik KIM ; Sung Soo KIM ; Soo Kyung BAE
Journal of the Korean Knee Society 1991;3(1):46-53
No abstract available.
Extremities*
;
Limb Salvage*
;
Tibia*
4.Mondor's Disease in Antecubital Area.
Jung Min BAE ; Man Jin JUNG ; I Nam GU ; Ki Hoon JUNG ; Sung Han BAE
Journal of the Korean Surgical Society 2006;71(2):149-151
Mondor's disease is also called thrombophlebitis and it is not a common condition. The characteristics finding of Mondor's disease is a subcutaneous cord that is tender and tense. This disease commonly occurs in the breast and abdomen. The etiology of Mondor's disease is unknown, but the generally agreed on causes are trauma, excessive exercise and breast surgery. On rare occasions, this disease is related to malignancy, pregnancy, filariasis and so on. This disease is self limiting and it is usually treated conservatively and symptomatically. We treated one woman who had Mondor's disease on the anterior side of the left elbow. This is a very rare location for Mondor's disease and so clinicians need to be aware about the possibility of this unusual presentation for this disease.
Abdomen
;
Breast
;
Elbow
;
Female
;
Filariasis
;
Humans
;
Pregnancy
;
Thrombophlebitis
;
Transcutaneous Electric Nerve Stimulation
5.Surgery of Intractable Epilepsy with Calcified Mass Lesions in the Temporal Lobe.
Ill Man KIM ; Eun Ik SON ; Jung In BAE ; Chang Chull LEE ; Dong Won KIM ; Man Bin YIM ; In Hong KIM
Journal of Korean Neurosurgical Society 1995;24(11):1345-1351
We present 10 patients who underwent temporal lobe surgery for seizure control on our institution between December, 1992 and October, 1994. Preoperative neuroimaging studies of all 10 patients showed calcified mass lesions within the temporal lobe. Among them, 5 cases had mesial temporal calcified mass close to the hippocampus, 3 diffuse mass in the temporal lobe or multilobes and 2 in the temporal tip. All patients presented with complex partial seizure and seven had secondary generalization from their seizures. The duration of epileptic seizure varied between 4 and 23 years(mean 13 year). The patients were refractory to therapeutic levels of anticonvulsant medication. Presurgical evaluations of epilepsy included a detailed clinical history, multiple scalp/shenoidal EEG, prolonged Video-EEG monitoring, neuroimaging, neuropsychological test, WADA test and invasive study with subdural strip electrodes. Anterior temporal lobectomy with lesionectomy were performed in six cases and anterior temporal lobectomy in four cases using intraoperative electrocorticography(EcoG) and/or functional mapping under local or general anesthesia. The extent of resection of amygdala and hippocampus were determined according to electrocorticographic findings. The verified histopathology of the calcified lesions revealed 1 oligodendroglioma, 1 mixed glioma, 1 arterioveous malformation, 1 paragonimiasis, 2 neurocysticercosis, 1 other parasitic granuloma and 3 calcified fibrous nodule. In four patients, severe hippocampal sclerosis with neuronal cell loss and gliosis were observed. After a mean postoperative follow-up of 9 months, 9 patients showed a seizure-free outcome and one patient a significant reduction in seizure activity. We conclude from our studies that temporal lobe surgery for patients refractory to therapeutic levels of long-term anticonvulsant medication can result in excellent postoperative seizure-free outcome in the majority of the patients, and that brain tumors, vascular malformations, and parasitic infections may be considered as etiologic factors of calcified mass lesions in the temporal lobe of such patients.
Amygdala
;
Anesthesia, General
;
Anterior Temporal Lobectomy
;
Brain Neoplasms
;
Electrodes
;
Electroencephalography
;
Epilepsy*
;
Follow-Up Studies
;
Generalization (Psychology)
;
Glioma
;
Gliosis
;
Granuloma
;
Hippocampus
;
Humans
;
Neurocysticercosis
;
Neuroimaging
;
Neurons
;
Neuropsychological Tests
;
Oligodendroglioma
;
Paragonimiasis
;
Sclerosis
;
Seizures
;
Temporal Lobe*
;
Vascular Malformations
6.ST Segment Depression in Lateral Leads in Inferior Wall Acute Myocardial Infarction.
Jin Man CHO ; Heung Sun KANG ; Chung Whee CHOUE ; Kwon Sam KIM ; Jung Sang SONG ; Jong Hwa BAE
Korean Circulation Journal 1998;28(11):1836-1840
BACKGROUND: The electrocardiogram may provide valuable information regarding the identity of the culprit coronary artery and the location of obstructing lesion within the artery, which may be of guidance in selecting the therapeutic modality. Previous studies have concluded that changes in lateral leads (I, aVL, V5, V6) are predictive of left circumflex coronary artery obstruction in inferior wall acute myocardial infarction. Elect-rocardiographic criteria for determining the location of the obstructing lesion, however, have not been well established. The purpose of this study is to investigate the patterns of ST segment depression in lateral leads in inferior wall acute myocardial infarction and the obstruction site of culprit artery according to ST segment depression in lateral leads. METHODS: We examined 78 patients with inferior wall acute myocardial infarction analizing their electrocardiogram and coronary angiography which performed during acute hospitalization. RESULTS: Of the fifty-five patients in which the culprit artery could be determined, 1)in 41 the culprit artery was the right coronary artery (19 proximal to the right ventricular branch and 22 distal), and in 14 the left circumflex coronary artery (7 proximal to the first obtuse marginal branch or involving a high first obtuse marginal branch, and 7 with distal obstruction). 2)Significant ST depression (ST< or =1 mm) in leads I and aVL was more common in right coronary artery obstruction (p<0.05 and p=0.01 respectively) than left circumflex artery. 3)It was difficult to define the location of obstruction with ST segment change of lateral precordial leads (V5, V6). CONCLUSIONS: In acute inferior wall myocardial infarction, ST segment depression in lateral limb leads (I, aVL) can be indicative of the right coronary artery obstruction and the ST segment depression pattern in lateral precordial leads was not indicative of the site of obstruction.
Arteries
;
Coronary Angiography
;
Coronary Vessels
;
Depression*
;
Electrocardiography
;
Extremities
;
Hospitalization
;
Humans
;
Inferior Wall Myocardial Infarction
;
Myocardial Infarction*
7.A case of infection-associated hemophagocytic syndrome associated with CMV mononucleosis.
Sang Koo KANG ; Suk Bae CHUN ; Man JUNG ; Yung Keun RYOO ; Kwan Soo CHOI ; Ji Woon KIM
Korean Journal of Infectious Diseases 1993;25(4):387-391
No abstract available.
Lymphohistiocytosis, Hemophagocytic*
8.Major abdominal vascular injuries
Myung Ho OH ; Jung Hwan CHOI ; Young Man BAE ; Yong Sik MOON ; Yong Kil SUH ; Hoong Jae ZOO
Journal of the Korean Society for Vascular Surgery 1992;8(1):47-62
No abstract available.
Vascular System Injuries
9.The development of Genu Valgum of the Affected Limb in Legg-Calve-Perthes Disease.
Sung Man ROWE ; Sung Taek JUNG ; Hyoung Yeon SEO ; Bong Hyun BAE ; Myung Sun KIM ; Kyung Soon PARK
Journal of the Korean Hip Society 2006;18(4):173-181
Purpose: Genu valgum in Legg-Calve-Perthes disease (LCPD) is not a known complication. We investigated whether this valgus tendency is a complication of femoral varus osteotomy (FVO) or the sequela of the disease process itself, and what are the related factors. Materials and Methods: 35 patients treated by FVO and 38 by abduction orthosis (AO) were selected for this study. Only those patients with unilateral involvement, fragmentation stage, Catterall Group III or IV, and who were followed-up to full skeletal maturity were included in the study. We measured mechanical axis deviation percentage and hip-knee-ankle angle for femorotibial alignment, and mechanical lateral distal femoral angle and medial proximal tibial angle (mMPTA) for knee orientation on teleoroentgenograms and compared the affected and normal limbs. Results: All measurements, excluding the mMPTA, demonstrated a tendency of relative genu valgum versus the opposite normal limbs. This tendency was observed in both groups. There was no statistically significant difference between the two groups. Conclusion: Genu valgum occurred in 66% to 70% of the LCPD patients. Four factors were found to be significantly correlated with valgus shift: increased medial bowing of the femoral neck, decreased acetabulum head index, coxa magna, and limb shortening. Multivariate regression analysis identified limb shortening as the factor most responsible for valgus shift.
Acetabulum
;
Axis, Cervical Vertebra
;
Extremities*
;
Femur Neck
;
Genu Valgum*
;
Head
;
Hip
;
Humans
;
Knee
;
Legg-Calve-Perthes Disease*
;
Orthotic Devices
;
Osteotomy
10.A Case of Complex Cardiac Myxoma Combined with Nipple Myxoma.
Gwang Gook KIM ; Heung Sun KANG ; Gye Won LEE ; Min Su SONG ; Jin Man CHO ; Jung Hwi CHO ; Jung Sang SONG ; Jong Hwa BAE
Korean Circulation Journal 1998;28(3):453-457
The majority of cardiac myxoma occur sporadically as isolated lesions in the left atrium of middle-aged women. However, a familial form and a syndrome form of this lesion have also been identified. The syndrome myxoma can present itself with pigmented skin lesions and peripheral or endocrine neoplasms. The familial and syndrome forms of cardiac myxomas can usually be distinguished from the sporadic form by their occurrences at younger ages, their unusual locations, the multicentricity of the lesions, and the presence of rare pathological conditions. In addition, a higher rate of recurrent lesions is usually associated with the familial and syndrome forms of this disease. We present a case of complex cardiac myxoma with pigmented skin lesions and breast myxoma and report it with a review of literature.
Breast
;
Female
;
Heart Atria
;
Humans
;
Myxoma*
;
Nipples*
;
Skin