Purpose: The purpose of this study was to investigate the prevalence of knee anterior and posterior cruciate ligament operation performed in Korea from 2015 to 2018. Methods: The participants of the study were 62,213 patients with knee anterior and posterior cruciate ligament operation provided by the big data from the Korea Health Insurance Review and Assessment Service from 2015 to 2018. Using the Korean standardized population of the National Statistical Office, the prevalence rate per 100,000 persons was analyzed by dividing them into sex and age. Results: As a result, the prevalence of knee anterior and posterior cruciate ligament operation by age from 2015 to 2018 was high between 20 and 29 years for men, while that for women was high between 10 and 19 years. Conclusion The prevalence rate per 100,000 persons of knee ligament was higher in the 20s for men, while in the 10s for women.