No abstract available.
Humans ; Liver Cirrhosis* ; Liver*

Foreatiers disease is a peculiar type of ankylosing hyperostosis of the spine characterized by ossification of the anterior and right lateral aspects of the vertebral column, particularly in the thoracic region. The clinical, pathological and reontgenographic features of the disorder allowed its differentiation from other spinal diseases including ankylosing spordylitis and osteoarthritis. A case of Forestiers disease is presented with brief review of literatures.
Hyperostosis ; Hyperostosis, Diffuse Idiopathic Skeletal ; Osteoarthritis ; Spinal Diseases ; Spine

We studied two hundread cases of replantations-61 cases of major limb replantation and 139 cases of finger replantation. 53 of 179 patients had multiple amputation. The most common cause of amputation was cutting-machine injury and the next one was belt and roller injury. The patients were followed than 6 months, ranging 6 months to 5 years and 10 months, averaging 36 months. The success rate of replantation is 86.9%(53/61) in the amputated limbs and 80.6%(112/139) in the amputated digits. Main causes of failure were tissue crushing, vessel thrombosis, long ischemic time, and amputation wound infection. Common complications were infection (25 cases), delayed union(7 cases), nonunion(2 cases), bleeding tendency and hematoma formation due to systemic heparinization(5 cases). We used Seddon's classification to assess the recovery of the nerve function of the replanted limbs and digits. 84.6 % of success cases of limb replantation presented the excellent result in the motor fuction recovery and 89.1% also presented the excellent sensory recovery. 89.8% of the success cases of the digit replantation showed the excellent result in the sensory recovery. The factors influencing the functional recovery of the replantation surgery were mechanism of injury, ischemic time, surgical technique, numbers of anastomosed vessels, ratio between anastomosed artery and vein, and wound infection. This analysis demonstrated that strict selection of the indication or the replantation is the first step in the limb and digit replantation surgery.
Amputation ; Arteries ; Classification ; Extremities ; Fingers ; Hematoma ; Hemorrhage ; Humans ; Operative Time ; Replantation ; Thrombosis ; Veins ; Wound Infection

Malignant lymphoma is neoplastic transformation of cells that reside predominantly in lymphoid tissues. Malignant lymphoma involving the eye is a rare disease. Malignant lymphoma of the lid is extremely rare. The authors experienced a case of malignant lymphoma involving the lid in a 62 year-old male patient. At first visit, the patient complained of a palpable painless mass on the left upper eye lid. Later, the malignant lymphoma was confirmed by histopathologic examination. As for treatment, the lid mass excision was performed and 10 MeV electron beam 4000 rad radiotherapy was followed.
Eyelids* ; Humans ; Lymphoid Tissue ; Lymphoma* ; Male ; Middle Aged ; Radiotherapy ; Rare Diseases

We conducted a retrospective study of 45 penetrating keratoplasties (39 patients) for keratoconus from March 1986 to February 1991 at St. Mary's Hospital, Catholic University Medical College. The follow-up period was at least over 1 year. The penetrating keratoplasties were performed most commonly in the interval between 1 and 5 years after the diagnosis of keratoconus (25 patients; 64.1%). The hard contact lenses were the most commonly used for visual correction before penetrating keratoplasty. Corneal scar was the most common indication for keratoplasty (35 eyes: 77.8%). The most common postoperative complication was loose suture (14 eyes; 31.1%). Overall, 43 out of the 45 corneal transplants (95.6%) remained clear and these eyes attained best-corrected visual acuity of 0.5 or better.
Cicatrix ; Contact Lenses ; Corneal Transplantation ; Diagnosis ; Follow-Up Studies ; Humans ; Keratoconus* ; Keratoplasty, Penetrating* ; Postoperative Complications ; Retrospective Studies ; Sutures ; Visual Acuity

BACKGROUND: The survival in patients with hepatocellular carcinoma (HCC) has recently been improved by the advancement in the early detection of HCC. Among the various treatment modalities, the surgical resection has been considered as the most effective for small HCC, and the clinical course of patients with small HCC who underwent curative resection is known to be dependent on the etiology of HCC. Since the differences in the etiology of HCC depend on the different geographical area, it is necessary to verify the clinical outcomes and their affecting factors in patients with small HCC after curative resection in Korea, one of the hepatitis- B-virus(HBU)-endemic areas. METHODS: A total of 89 patients with small HCC (or=50 years old), Child's classification and vascular invasion were factors affecting the rate of recurrence. CONCLUSION: These results verify that the clinical outcomes of patients with small HCC after curative resection in Korea are similar to those of patients with different etiology of HCC in other geographic areas. To improve the prognosis of patients with small HCC after curative resection, strict preoperative evaluation of the presence of vascular invasion and postoperative preservation of liver function are necessary as well as the close postoperative follow-up for the early detection of recurrence.
Carcinoma, Hepatocellular* ; Classification ; Follow-Up Studies ; Hepatitis B Surface Antigens ; Humans ; Korea ; Liver ; Liver Cirrhosis ; Mortality ; Prognosis ; Recurrence ; Retrospective Studies ; Seoul ; Survival Rate

Laparoscopic cholecystectomy (LC) is considered as the gold standard operation for the removal of a nonmalignant, diseased gallbladder. With the increasing number of LCs, a number of gallbladder carcinomas have been unexpectedly found either during or following this procedure. The removal of unexpected gallbladder carcinomas by LC can cause also a new complication, port site metastasis (PSM), which is developed by the implantation of tumor cells into the abdominal wall at the port site. We report a rare case of PSM of gallbladder carcinoma which was unsuspected at the time of LC. A 65-year-old man underwent LC at another hospital for calculous cholecystitis. The histologic examination revealed an adenocarcinoma of the gallbladder infiltrating the muscle wall. Despite the surgeon's advice, the patient refused any additional treatment. Ten months after surgery, he visited our hospital because of a painful and palpable subcutaneous mass at the scar of the periumbilical trocar incision. The mass was biopsed and histological examination confirmed metastasis from the gallbladder carcinoma.
Abdominal Wall ; Adenocarcinoma ; Aged ; Cholecystectomy, Laparoscopic* ; Cholecystitis ; Cicatrix ; Gallbladder* ; Humans ; Neoplasm Metastasis* ; Surgical Instruments

Background: This study evaluated the effects of a mobile diabetes management program called “iCareD” (College of Medicine, The Catholic University of Korea) which was integrated into the hospital’s electronic medical records system to minimize the workload of the healthcare team in the real clinical practice setting. Methods: In this retrospective observational study, we recruited 308 patients. We categorized these patients based on their compliance regarding their use of the iCareD program at home; compliance was determined through self-monitored blood glucose inputs and message subscription rates. We analyzed changes in the ABC (hemoglobin A1c, blood pressure, and low-density lipoprotein cholesterol) levels from the baseline to 12 months thereafter, based on the patients’ iCareD usage patterns. Results: The patients comprised 92 (30%) non-users, 170 (55%) poor-compliance users, and 46 (15%) good-compliance users; the ABC target achievement rate showed prominent changes in good-compliance groups from baseline to 12 months (10.9% vs. 23.9%, P<0.05), whereas no significant changes were observed for poor-compliance users and non-users (13.5% vs. 18.8%, P=0.106; 20.7% vs. 14.1%, P=0.201; respectively). Conclusion Implementing the iCareD can improve the ABC levels of patients with diabetes with minimal efforts of the healthcare team in real clinical settings. However, the improvement of patients’ compliance concerning the use of the system without the vigorous intervention of the healthcare team needs to be solved in the future.

BACKGROUND: There is a strong evidence that administration of anti-tumor drugs triggers apoptotic death of target cells. Therefore, quantitation of the 0early apoptotic cells could provide a very useful information for clinicians planning anti-tumor strategies. Therefore, we measured the amount of early apoptotic cells using annexin-FITC/PI dual fuorescence method by which early changes of apoptotic cell membrane could be detected. We also measured DNA content of apoptotic cells by PI single stain and performed DNA fragment assay simultaneously. METHODS: HL-60 cell line were cultured under 100, 200 ng/mL adriamycin for 12, 24, 36, 48 hours. Quantitation of the early apoptotic cells was done using flow cytometry with annexin-FITC and Propidium iodide (PI) dual fluorescence stain. And DNA content of the HL-60 cells was measured using PI single stain after fixing the cells. DNA ladder assay was also performed by agarose gel electrophoresis. RESULTS: The early apoptotic cells were 40.5% at adriamycin 100 ng/mL, after 24 hours culture and the secondary necrotic cells were 94.7% at adriamycin 200 ng/mL after 48 hours culture. There was a good correlation between annexin-PI stain and DNA content analysis. We could find DNA fragmentation on agarose gel electrophoresis. CONCLUSION: Quantitation of the early apoptotic cells using flow cytometry with annexin-PI dual fluorochrome stain and the DNA content analysis with PI single stain could be a good parameter for anti-apoptotic strategies.
Cell Membrane ; DNA ; DNA Fragmentation ; Doxorubicin ; Electrophoresis, Agar Gel ; Flow Cytometry* ; Fluorescence ; HL-60 Cells ; Humans ; Propidium