1.The Lumbar Discogram Incidental to the Operation: Analysis of 35 Cases
Byung Kook KIM ; Young Joe KIM ; Hun Soo JUNG
The Journal of the Korean Orthopaedic Association 1976;11(1):11-18
Since the time when the lumbar discogram was used as the clinical diagnostic method for the first time in 1952, many problems have been pointed out to this method, and moreover, in presentday tendencies for the diagnostic method, the lumbar discogram is carried on even useless by majority. One of the important reasons is that so many studies for the lumbar discograms have reported so many false positive lumbar discograms at the high ratio. Hower we found a certain usefulness of the lumbar discogram incidental to the operation. The purposes of our operative lumbar discogram are those; 1) to observe the radiological configuration of the lumbar discogram. 2) to measure the amount of the the dye injected into normal and abnormal lumbar discs, especially in our Koreans. 3) for confirmation of the diagnosis when the myelographic finding is suspicious. 4) for confirmation of the Ievel especially when the number of the possible lesion is more than one. We investigated and analyzed the 35 lumbar discograms of 26 patients and compiled the statistics.
Diagnosis
;
Humans
;
Methods
2.The Effect of Hypobaric Priming Solutions on Extracorporeal Circulation during Open Heart Surgery.
Sun Ok SONG ; Jung Kook SUH ; Heung Dae KIM
Yeungnam University Journal of Medicine 1984;1(1):101-106
Before beginning the extracorporeal circulation, perfusionists should supply oxygen into the oxygenator and establish blood flow through the blood line of the heart-lung machine. But these manipulation can induce severe hypocarbic state of priming solutions due to wash out of CO2 gas in the solution. This study was carried out to examine the relationship of blood gas changes between hypocarbic priming solutions and body circulation in 15 patients undergoing open heart surgery with extracorporeal circulation. PaCO₂, pH, buffer base and PaO2 were measured from priming solutions before and 15 minutes after the extracorporeal circulation. The results were as follows; 1) Before the extracorporeal circulation, mean PaCO₂ level was 12.1±7.8 mmHg in the priming solution. However, 15 minutes after extracorporeal circulation, the PaCO₂ level was maintained at 35.7±5.7 mmHg. 2) pH in the priming solution was variable from 6.93 to 7.99 (mean 7.45±0.29), but after 15 minutes it was ranged from 7.28 to 7.42 (mean 7.35±0.05). 3) Mean buffer base level in the priming solution was 7.9±3.5 mmol/l. but after 15 minutes, it was 19.6±1.2 mmol/l. 4) Mean PaO₂ level in the priming solution was 667.1±45.6 mmHg, but after 15 minutes, it was 280.7±131.7 mmHg.
Extracorporeal Circulation*
;
Heart*
;
Heart-Lung Machine
;
Humans
;
Hydrogen-Ion Concentration
;
Oxygen
;
Oxygenators
;
Thoracic Surgery*
3.Effects of Manually Controlled Ventilation on Gas Exchange during General Anesthesia.
Jung Kook SUH ; Ill Sook SUH ; Heung Dae KIM
Yeungnam University Journal of Medicine 1984;1(1):95-100
In the beginning of anesthetic training, one of the clinical practices that anesthetists have to learn is manually controlled ventilator techniques. The popularity of manually controlled ventilatory techniques has been gradually decreased with increased use for anesthetic ventilators. However it is important and basic for the anesthetists to master manually controlled ventilator techniques skillfully. Recently, we analyzed the arterial blood gas in 30 cases before and during general anesthesia, and studied the effects of the manually controlled ventilation on the pulmonary gas exchange. The results were as follow; 1) Mean value of PaCO₂ during the manually controlled ventilation, 29.9±2.0 mmHg was decreased statistically comparing with that of PaCO₂ before the anesthesia, 39.8±2.8 mmHg. 2) Mean values of pH and HCO₃⁻ during the manually controlled ventilation were 7.48±0.03, 22.2±2.4 mEq/1, respectively and values before the anesthesia were 7.41±0.02, 25.2±1.8 mEq/1, respectively. 3) Mean value of PaO₂ and O₂ saturation during the manually controlled ventilation were 270.0±28.8 mmHg, 99.6±0.2%, respectively and values before the anesthesia were 92.5±4.0 mmHg, 96.9±1.0%, respectively. These results indicates that manually controlled ventilation at our department of anesthesiology produced mild hyperventilatory state. However these were no significant changes in cerebral blood flow and other biochemical parameters.
Anesthesia
;
Anesthesia, General*
;
Anesthesiology
;
Cerebrovascular Circulation
;
Hydrogen-Ion Concentration
;
Pulmonary Gas Exchange
;
Ventilation*
;
Ventilators, Mechanical
4.The Change of Arterial Blood Gas during High Frequency Jet Ventilation via 14 French Suction Catheter in Microlaryngeal Endoscopic Surgery.
Hyun Jung KIM ; Kook Hyun LEE ; Mi Sook GWAK
Korean Journal of Anesthesiology 1997;33(6):1116-1120
BACKGROUND: It is a routine practice that High Frequency Jet Ventilation (HFJV) is applied through a 14~16 gauge (about 12 French (Fr.)) angiocath. The 14 Fr. suction catheter which is similar to angiocath in its internal diameter is commonly available in the operating room. We evaluated the suction catheter as a carrier of HFJV in point of ventilation, oxygenation and operating field during HFJV at microlaryngeal endoscopic surgery (MES). METHODS: Fifteen adult patients undergoing HFJV via 14 Fr. suction catheter during MES were studied. Time-based arterial blood gas analyses were done before and after HFJV. The movement of operating field was examined using laryngoscopic examination by surgeon and anesthesiologist. We also evaluated complications such as abdominal distension, barotrauma and so on. RESULTS: The mean arterial oxygen tension was maintained above 250 mmHg all the time during HFJV. The mean carbon dioxide tension was less than 51 mmHg. There were no remarkable catheter movement and complications. CONCLUSION: The 14 Fr. suction catheter is a good replacement of angiocath. It provided good operating field, ventilation and oxygenation without complications.
Adult
;
Barotrauma
;
Blood Gas Analysis
;
Carbon Dioxide
;
Catheters*
;
High-Frequency Jet Ventilation*
;
Humans
;
Operating Rooms
;
Oxygen
;
Suction*
;
Ventilation
5.Report of Two Cases of Hypomelanosis of Vitiligo Type Probably due to Benoquin.
Mee Sook KIM ; Jung Ja HONG ; Hong Il KOOK
Korean Journal of Dermatology 1974;12(4):305-308
Two cases of vitiligo-type hypomelanosis followed by the local application of Benoquin ointment for the treatment for the treatment of melasma are reported. These two cases of hypomelanosis are unwanted and unintended side effects probably caused by the application of monobenzyl ethers of hydrcquinone (monobenzone). Monobenzone blocks the enzyme tyrosinase and thereby prevents the conversion of tyrosine to dihydroxyphenylanine, a precursor of melanin, and since this does not destroy melanocyte or facilitate the loss of melanin. The skin contact with the material will not occur, repigmentation will slow but eventuaIly complete.
Ether
;
Ethers
;
Hypopigmentation*
;
Melanins
;
Melanocytes
;
Melanosis
;
Monophenol Monooxygenase
;
Skin
;
Tyrosine
;
Vitiligo*
6.Clinical Application of D-penicillamine and Levamisole in Pheumatoid Arthritis
Eun Woo LEE ; Young Bok JUNG ; Heon Kook KIM
The Journal of the Korean Orthopaedic Association 1983;18(1):81-88
Penicillamine is a component of the penicillin molecule which was identified in the urine of patients with chronic liver disease who were receiving penicillin for the treament of intercurrent infections. Walshe demostrated its effectiveness as copper chelating agent and introduced it into the treatment of Wilson's disease. In addition, it has been shown to be effective in treatment of cystinuria, heavy metal poisoning, and rheumatoid arthritis. Levamisole is a three-ringed molecule which has been used as broad-spectrum antihelminthic drug. Levamisole is capable of T cell immune enhancer and has variable effects on antibody production, Since immune enhancer may affect multiple cell types, either directly or indirectly, and may operate on the adenylcyclase-cAMP-prostaglandin system, the results of treatment may be complex. Levamisole has been shown to be effective in rheumatoid arthritis by several study. We analysed the 29 rheumatoid arthritis patients who were treated at Deartment of Orthopedic Surgery, Chung Ang University Hospital from June, 1978 to June, 1982; among them 17 recieving penicillamine and 12 recieving levamisole. The results were as follows: 1. There were statistically significant improvement in ESR. But there were decrease in mean WBC and platelet counts in patients recieving penicillamine or levamisole. Hemoglobin was not affected. 2. Side effects led to withdrawal of treatment in 8(47%) patients in the penicillamine group and 5(42%) in the levamisole group. 3. In 17 patients having penicillamine treatment, one patient had complete remission(8%).
Antibody Formation
;
Arthritis
;
Arthritis, Rheumatoid
;
Copper
;
Cystinuria
;
Hepatolenticular Degeneration
;
Humans
;
Levamisole
;
Liver Diseases
;
Orthopedics
;
Penicillamine
;
Penicillins
;
Platelet Count
;
Poisoning
7.Polycystic ovary in torsion combined with stage in endometrial carcinoma.
Jung In YANG ; Suk Jung KIM ; Byung Seok LEE ; Dong Jei CHO ; Kook LEE ; Chan Ho SONG
Korean Journal of Obstetrics and Gynecology 1991;34(10):1481-1487
No abstract available.
Endometrial Neoplasms*
;
Female
;
Ovary*
8.A Case of Complete Hydatidiform Mole in a triplet pregnancy following In Vitro Fertilization and Embryo Transfer.
Gwang Kook KIM ; Myung Chul KIM ; Jin Soo PARK ; Hyuk Dong HAN ; In Bae JUNG
Korean Journal of Obstetrics and Gynecology 2000;43(11):2062-2066
A complete hydatidiform mole coexisting with a fetus is a rare condition, particularly when diagnosed after IVF-ET. In spite of the wide spread use of assisted reproductive technology, there have been, to our knowledge, only few reported cases of molar pregnancy after IVF-ET. At present, there are limited data to guide the antenatal management of a complete hydatidiform mole coexisting with fetuses. A complete mole can coexist with a normal, healthy fetus who can be carried to term, with good outcome. But, patients who desire to continue the pregnancy after such a diagnosis must be cautioned about the potential for severe medical complications and developing persistent gestational trophoblastic tumor. We report here a case of complete hydatidiform mole in a triplet pregnancy coexistent with two live fetuses following in IVF-ET.
Diagnosis
;
Embryo Transfer*
;
Embryonic Structures*
;
Female
;
Fertilization in Vitro*
;
Fetus
;
Humans
;
Hydatidiform Mole*
;
Pregnancy
;
Pregnancy, Triplet*
;
Reproductive Techniques, Assisted
;
Triplets*
;
Trophoblastic Neoplasms
9.Protective Effect of Propofol on Endothelial Damage Induced by Reactive Oxygen Species in Rabbit.
Kyung Hun KIM ; Jung Kook SUH ; Hwa Nyon KIM ; Sang Yoon CHO
Korean Journal of Anesthesiology 2003;44(5):684-690
BACKGROUND: Reactive oxygen species (ROS) induce lipid peroxidation and tissue damage in the isolated rabbit thoracic aorta. The aim of this study was to explore the influence of the propofol and midazolam against ROS in the isolated rabbit thoracic aortic endothelium. METHODS: Eighteen white male rabbits (weighing 2.0-2.5 kg) were used. The thoracic aorta was dissected free and cut into rings (3-4 mm) and then suspended in a organ bath filled with 10 ml Krebs solution bubbled with 5% CO2 95% O2 at 37 degrees C. Aortic rings were then equilibrated for 90 min, and a resting tension of 1.5 g was applied. The Krebs solution was changed every 15 min. Isometric tension was recorded with transducer coupled to a data acqusition system (Biopac Inc. USA) on a PC. After precontraction with norepinephrine (NE, 10(-6)M), changes in tension were measured following the cumulative administration of acetylcholine (ACh 3x10(-7), 10(-6) and 3x10(-6)M) and nitroglycerin (NTG, 10(-5)M). Data are expressed as percentage of the 10 5 M NTG-induced relaxation (ACh/NTG). The ACh/NTG, before and after electrolysis were defined as the control and the experimental groups. The aortic rings were pretreated with propofol (3x10(-5), 10(-4), 3x10(-4) and 5.7x10(-4) M, n = 8, 10, 15, 13), midazolam (10(-4)M, n = 7), catalase (1,000 U/ml, n = 12), mannitol (3x10(-4)M, n = 5) or not pretreated group (Free, n = 6). After 30 minutes, the aortic rings were exposed to ROS generated by electrolysis (DC 9 V, 20 mA, aortic rings 1 cm away from electrode) in Krebs solution for 2 minutes, which was then changed for physiologic buffered salt solution. The aortic rings were precontracted with NE and vasorelaxation was induced with ACh and NTG at the above mentioned concentrations. RESULTS: Propofol produced vasorelaxation of NE-precontracted thoracic aorta in a dose-dependent fashion in all groups of propofol (3x10(-5), 10(-4), 3x10(-4) and 5.7x10(-4)M) even after ROS attack (P < 0.05 vs control value). Catalase produced vasorelaxation after ROS attack (P < 0.05 vs control value).On the other hand, ACh-induced significant endothelium-dependent vasorelaxation were not observed in the midazolam or mannitol pretreated group or the non-pretreated group (P <0.05 vs control group). CONCLUSIONS: These findings suggest that propofol and catalase preserve ACh induced endothelium-dependent vasorelaxation and that propofol has a concentration dependent ROS scavenging effect like catalase.
Acetylcholine
;
Aorta, Thoracic
;
Baths
;
Catalase
;
Electrolysis
;
Endothelium
;
Hand
;
Humans
;
Lipid Peroxidation
;
Male
;
Mannitol
;
Midazolam
;
Nitroglycerin
;
Norepinephrine
;
Propofol*
;
Rabbits
;
Reactive Oxygen Species*
;
Relaxation
;
Transducers
;
Vasodilation
10.The role of exchange transfusion as a therapy for neonatal DIC.
Jung Tak KIM ; Kook In PARK ; Ran NAMGUNG ; Dong Gwan HAN ; Kir Young KIM
Journal of the Korean Pediatric Society 1991;34(1):31-40
No abstract available.
Dacarbazine*
;
Disseminated Intravascular Coagulation