1.RNAi: A Recent Revolutionary Tool for Understanding of Basic Biology.
Dong Kil JUNG ; Young Suk CHO ; Won Kil LEE
Korean Journal of Clinical Microbiology 2007;10(1):1-5
RNA interference (RNAi) is a gene-silencing technology by which small double-stranded RNAs are used to target the degradation of RNA with complementary sequence. RNAi is found in a wide variety of organisms (Caenorhabditis elegans, insects, plants, microorganisms and animals). With RNAi, we have harnessed the gene function to be explored, revolutionized our ability to perform large-scale genetic screens, and even therapeutic potential.
Biology*
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Insects
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RNA
;
RNA Interference
;
RNA, Double-Stranded
2.A Case of Lymphangioma Circumscriptum.
Jung Bock LEE ; Chang Jo KOH ; Kil Yun CHO ; Tae Ha WOO
Korean Journal of Dermatology 1973;11(1):49-52
Lymphangioma circumscriptum is a rare disease and the lesions are indistinguishable, clinically and histologically, from lymphangiectasis. The only difference is that lymphangiectasis is usually bilateral and develops in adult or late life, ie, condary to irradiation, surgical interruption, or some malignancies, but lymphangioma circumscriptum is congenital disease or develops soon after birth.
Adult
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Humans
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Lymphangiectasis
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Lymphangioma*
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Parturition
;
Rare Diseases
3.Comparison of the results of multistix®-SG and comber-9-Test®RL urine dipstick assay.
Dae Chul KIM ; Kyung Dong KIM ; Bo Chan JUNG ; Chung Sook KIM ; Kil Ho CHO
Yeungnam University Journal of Medicine 1991;8(1):42-52
Two types of urine dipstick assays, Multistix-SG and Comber-9-Test RL, were compared for compatibility, accuracy, specificity and predictive values of a positive and negative test in 501 patients' urine and artificially prepared specimen. We found that the results of semiquantitative tests of Multistix-SG and Comber-9-Test RL performed were statistically similar in patients' specimen. The urinary leukocyte esterase tests of Comber-9-Test RL assays compared with urine sediment microscopy in regard to compatibility, sensitivity, specificity, and predictive values of a positive and negative test 83.7%, 48.1%, 90.3%, 47.4% and 90.1%, respectively. The urinary nitrite tests of Comber-9-Test RL assays compared with urine culture tests, in regard to compatibility, sensitivity, specificity, and predictive values of a positive and negative test were 90.3%, 19.4%, 84.7%, 53.8% and 94.1, respectively. For the urinary protein, the sulfosalicylic acid method was the most sensitive test for any kinds of protein, and Multistix-SG appeared more sensitive than Comber-9-Test RL for the albuminuria. For the urinary bilirubin and glucose, two dipstick assays were similar in their diagnostic efficiency. Finally in the urinary occult blood tests, Comber-9-Test RL assays was more sensitive than Multistix-SG.
Albuminuria
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Bilirubin
;
Glucose
;
Leukocytes
;
Methods
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Microscopy
;
Occult Blood
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Sensitivity and Specificity
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Urinalysis
4.Periventricular leukomalacia: Ultrasonographic findings, risk factors and neurological outcome.
Kyeong Hee CHO ; Myoung Jae CHEY ; Se Jung SOHN ; Kil Hyun KIM ; Hak Soo LEE
Journal of the Korean Pediatric Society 1993;36(5):693-704
The thirty eight newborn infants with periventricular leukomalacia who were admitted to the neonatal intensive care unit of Gil General Hospital from March 1, 1988 to June 30, 1991, were investigated for ultrasonographic findings, risk factors and neurological outcome. The results were as follows: 1) There were 38 cases of PVL including 21 echogenic flarings and 17 cystic PVL's. 2) Mean birth weight was 2,250 gm and mean gestational age was 35 week. 3) Mean detection timing was 4th day in echogenic flarings and 18th day in cystic PVL's. 4) PVL's were located in the parietal region in 1 case and fronto-parieto-occipital in 3 cases. 5) Mean cyst size was 6 mm. 6) Multiple logistic regression analysis for the risk factors of PVL showed that low birth weight, apnea and seizure were the most significant contributing factors (p<0.05). 7) In the follow-up study of cystic PVL's, 7 cases showed improvement, 7 cases developed into multicystic encephalomalacia and 3 cases developed into atrophy. 8) Neurodevelopmental outcome of cystic PVL's showed nomal; 6.2%, minor neurodevelopmental defect; 43.8%, major neurodevelopmental defect; 31.2% and death; 18.8%. 9) Neurosonographic predictability for neurodevelopemental sequelae by cystic PVL's showed sensitivity; 63.6%%, specificity; 98.0%, positive predictive value; 92.8% and accuracy; 88.2%. 10) Major neurodevelopmental defect was more frequent, cyst size being larger and location being more extensive (p<0.05).
Apnea
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Atrophy
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Birth Weight
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Encephalomalacia
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Follow-Up Studies
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Gestational Age
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Hospitals, General
;
Humans
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Infant, Low Birth Weight
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Infant, Newborn
;
Intensive Care, Neonatal
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Leukomalacia, Periventricular*
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Logistic Models
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Rabeprazole
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Risk Factors*
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Seizures
;
Sensitivity and Specificity
5.Computer-assisted interpretative reporting system of serum CK and LD isoenzyme tests.
Dae Chul KIM ; Bo Chan JUNG ; Kil Ho CHO ; Kyung Dong KIM ; Chung Sook KIM
Korean Journal of Clinical Pathology 1991;11(2):349-362
No abstract available.
6.Primary endodermal sinus tumor of the common bile duct.
Kyeong Hee CHO ; Se Jung SOHN ; Kil Hyun KIM ; Hak Soo LEE
Journal of the Korean Pediatric Society 1992;35(9):1298-1302
No abstract available.
alpha-Fetoproteins
;
Common Bile Duct*
;
Endoderm*
;
Endodermal Sinus Tumor*
7.Paraplegia after Open Reduction of the Femoral Trochanteric Fracture in Ankylosing Spondylitis: A Case Report
Hyung Ku YOON ; Hoe Seung JEON ; Kwang Pyo JEON ; Dae Eun JUNG ; Nam Kil CHO
The Journal of the Korean Orthopaedic Association 1994;29(7):1695-1700
Ankylosing spondylitis is a chronic inflammatory disease of unknown etiology that affects spine, sacroiliac joint, and the large joints of the extremities, and lead to fibrous or bony ankylosis and deformity. The rigid ankylosed spine of ankylosing spondylitis is prone to fracture by minimal trauma, and the resulting fractures likely to be unstable and damage to spinal cord or cauda equina. The authors report a case of paraplegia in ankylosing spondylitis after open reduction of the femoral trohanteric fracture.
Ankylosis
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Cauda Equina
;
Congenital Abnormalities
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Extremities
;
Femur
;
Joints
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Paraplegia
;
Sacroiliac Joint
;
Spinal Cord
;
Spine
;
Spondylitis, Ankylosing
8.Clinical and Histological Analysis of 126 Cases of Gastric Polyps.
Jung Myung CHUNG ; Sang Hyuk LEE ; Sang Yong SEOL ; Gi Jeong CHO ; Hyoung Gyu SHIN ; Kil Hyon CHO
Korean Journal of Gastrointestinal Endoscopy 1995;15(1):40-45
The gastrointestinal polyp is a premalignant lesion in varying degree. According to the size, the pathology and the location of polyps, it should be removed. Polyps in the gastrointestinal tract can be removed by surgical excision, electrosurgery, cryotherapy, regional radiotherapy and laser therapy with some limitations. Considerable advance in therapeutic endoscopy as well as in diagnostic endoscopy along with newly developed instruments has now made it possible to excise gastrointestinal polyps by means of high frequency generator. We have underwent endoscopic polypectomy, strip biopsy and "O" ring ligation on gastric polyps in 112 patients who visited in this hospital from July l988 to January 1994, and the clinical characteristics including histopathology has been evaluated. Removed polyps were variable in size from less than 0.5 cm up to 4cm. Finally, we concluded that endoscopic polypectomy is a safe and relativly simple procedure and postpolypectomy complication can be considerably reduced by conservative antiulcer therapy.
Biopsy
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Cryotherapy
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Electrosurgery
;
Endoscopy
;
Gastrointestinal Tract
;
Humans
;
Laser Therapy
;
Ligation
;
Pathology
;
Polyps*
;
Radiotherapy
9.Breast Lymphoma: A Report of 2 Cases.
Soo Jung LEE ; Jin Wook LEE ; Mi Soo HWANG ; Kil Ho CHO ; Bok Hwan PARK ; Dong Sug KIM
Journal of the Korean Radiological Society 1994;31(4):763-766
The diagnosis of breast lymphoma is a prime consideration when a breast mass develops in a patient with a history of lymphoma either in lymphatic system or at other anatomic sites, with bilateral axillary lymph nodes enlargment. However, the radiologic findings of lymphoma in breast are known as non-specific. Breast lymphoma is extremely rare and it has never been reported in this country. We report two cases of breast lymphoma with mammographic and sonographic findings.
Breast*
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Diagnosis
;
Humans
;
Lymph Nodes
;
Lymphatic System
;
Lymphoma*
;
Ultrasonography
10.Ultrasonographic Features of Intra-abdominal Abscess.
Kil Ho CHO ; Kyung Hee JUNG ; Mi Soo HWANG ; Jae Chun CHANG ; Koing Bo KWUN ; Hyun Sik MIN
Yeungnam University Journal of Medicine 1985;2(1):87-93
Intraabdominal abscess usually causes distress with fever, leukocytosis, pain and toxicity. Diagnosis of intraabdominal abscess is occasionally difficult and it has high morbidity. However radiologic method, such as ultrasonography, CT scan, or RI scan are helpful to early detection of intraabdominal abscess. Among these methods, ultrasonography is a noninvasive technique and performed without discomfort to patient. And also differential diagnosis between cystic and solid lesion is very easy and sequential ultrasonography in same patient is valuable for the evaluation of treatment effect. We analyzed the ultrasonic features of 48 cases with intraabdominal abscesses and the results are as follows; 1. In total 48 cases, the intraabdominal abscesses were 30 cases, the retroperitoneal abscesses, 5 cases, and the visceral abscesses, 13 cases. 2. The causes of the intraabdominal abscesses were perforating appendicitis (25 cases), postoperative complications (5 cases), pyogenic and amebic hepatic abscesses (13 cases), and the other (5 cases). 3. Round or oval shaped lesions were 26 cases (54%), irregular shape, 18 cases (38%), and multiple abscess formation in 4 cases (8%). 4. The size of the lesions were between 5 and 10cm in diameter in 54% of total 48 cases, and the most frequent feature of the echo pattern of the lesions was cystic with or without internal echogenicity (69%).
Abdominal Abscess*
;
Abscess
;
Appendicitis
;
Diagnosis
;
Diagnosis, Differential
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Fever
;
Humans
;
Leukocytosis
;
Liver Abscess
;
Methods
;
Postoperative Complications
;
Tomography, X-Ray Computed
;
Ultrasonics
;
Ultrasonography