1.Influence of synthetic polyadenylic. polyuridylic acid on the productions of interferon-?and interleukin-4 in mice.
Jung Koo YOON ; Bong Ki LEE ; Jun Soo SHIN
Journal of the Korean Cancer Association 1993;25(4):586-594
No abstract available.
Animals
;
Interleukin-4*
;
Mice*
2.Operative Treatment of Winged Scapula: A Report of 2 Cases.
Ho Jung KANG ; Ki Deog KIM ; Sang Jin SHIN
The Journal of the Korean Orthopaedic Association 1999;34(5):845-848
Winging of the scapula is characterized clinically by a prominence of the vertebral border and inferior angle of the scapula. Trauma, neuritis, neural injury during surgical procedure and many other causes may develop winging of scapula. When pain and functional impairment persist, surgical intervention may become appropriate. We report two cases of winged scapula. One case was serratus anterior palsy due to blunt trauma, which was treated by transfer of teres major and pectoralis minor elongated with a tensor fascia strip. Another case was trapezius muscle palsy due to iatrogenic spinal accessary nerve injury, which was treated by transfer of the levator scapulae, rhomboid major and rhomboid minor muscle. In the former case, there was no weakness nor deformity of affected shoulder. In the later case, there was some residual pain and limitation of motion.
Congenital Abnormalities
;
Fascia
;
Neuritis
;
Paralysis
;
Scapula*
;
Shoulder
;
Superficial Back Muscles
3.Clinical Evaluation on Serial Changes of Serum Immunoglobulin E in Patients with Acute Myocardial Infarction.
Min Ki LEE ; Jung Yoo LEE ; Dong Il LEE ; Yeong Woo SHIN ; Yeong Kee SHIN
Korean Circulation Journal 1990;20(2):204-210
Serial changes of serum IgE, IgG, eosinophils were observed in 25 patients with acute myocaridial infarction and 20 ischemic heart disease without evidence of acute myocardial infarction and evaluated in terms of several parameters and its clinical significance. The results observed were as follows : 1) Serum IgE levels were propgressively elevated from the first hospital day(259+/-3IU/ml) up to peak level of the fifth hospital day(415+/-2IU/ml) and progressively lowered and returned to almost same level as the first hospital day on the twenty first hospital day. On the other hand control group showed significantly lower IgE levels throughout all hospital day and also did not showed serial change. 2) In the patient group with the initial serum IgE level above 200IU/m; showed significantly lower level of serum SGOT, CPK level than the group of below 200IU/ml group. This suggests the initial serum IgE level might have some correlation of the extent of myocardial necrosis. 3) In patients of acute myocardial infarction, ejection fraction was checked at discharge. Initial serum IgE level above 200IU/ml group showed significantly higher ejection fraction than below 200IU/ml group(59.4+/-13.5% vs 38.4+/-13.7%). 4) Serum IgE was checked concomittantly with serum IgE. It showed slightly decreasing tendency at third hospital day but not statistically significant. Eosinophil changed similar pattern as serum IgE but it was also not statistically significant. In conclusion, serial checking of serum IgE level in patient of acute myocardial infarction may give some help in prediction the clinical course and prognosis.
Aspartate Aminotransferases
;
Eosinophils
;
Hand
;
Humans
;
Immunoglobulin E*
;
Immunoglobulin G
;
Immunoglobulins*
;
Infarction
;
Myocardial Infarction*
;
Myocardial Ischemia
;
Necrosis
;
Prognosis
4.Measurement in the proximal part of the tibia in Korean..
Min Suk CHUNG ; Jung Ki SHIN ; Hee Jung CHO ; Kang JOO ; In Hyuk CHUNG
Korean Journal of Physical Anthropology 1992;5(2):201-209
No abstract available.
Tibia*
5.The Influences of Obesity on Bone Mineral Density in Children.
Ki Young CHANG ; Hye Jung YANG ; Young Kyu SHIN ; Sang Hee PARK ; Kee Hyoung LEE ; Ki Yeol LEE
Journal of Korean Society of Pediatric Endocrinology 2001;6(2):129-136
PURPOSE: Nutritional as well as genetic and hormonal factors play an important role in the bone mineralization during childhood and adolescence. There are several physical and metabolic changes in obese children, and these changes may influence on the mineralization of the skeleton. The studies about bone mineralization of obese children are rare and contradictory. This study was performed to evaluate the influence of childhood obesity on bone mineral density(BMD). METHODS: The BMD of 49 obese and 41 non-obese children were measured at lumbar spines(L2-L4) using dual energy X-ray bone absorptiometry. Then, the results were assessed and compared according to the degree of obesity and pubertal sex maturation. RESULTS: There were no significant differences in BMD between obese children and non-obese children(0.87+/-.19 g/cm2 vs 0.81+/-.13 g/cm2). BMD increased according to the Tanner' pubertal staging, and the most marked increment was observed at overt puberty. No sex difference in BMD was seen in both obese and non-obese children. BMD was highly correlated with age, height, weight and body mass index(BMI), but there was no significant correlation between BMD and osteocalcin. CONCLUSION: BMD of obese children was not significantly different from that of non-obese children, and BMD also was not changed according to the degree of obesity. These findings suggest that BMD is not influenced by obesity in children.
Adolescent
;
Bone Density*
;
Calcification, Physiologic
;
Child*
;
Humans
;
Obesity*
;
Osteocalcin
;
Pediatric Obesity
;
Puberty
;
Sex Characteristics
;
Sexual Maturation
;
Skeleton
6.Scar Quality and Hand Function after Moist Exposed Burn Ointment and Skin Graft Treatment in Full Thickness Hand Burn.
Ji Cheol SHIN ; Cheong Hoon SEO ; Ki Un JANG ; Ki Yang JUNG
Journal of the Korean Academy of Rehabilitation Medicine 2007;31(5):582-589
OBJECTIVE: To compare the scar formation and hand function between moist exposed burn ointment (MEBO) treatment and conventional skin graft in full thickness hand burns. METHOD: Prospective comparative study was done between MEBO treatment group and conventional skin graft group. Full thickness burn wound scars on dorsal hand were compared. Scars were assessed with the Vancouver scar scale and other objective measurement tools such as pigmentation, erythema, pliability, transepideramal water loss, thickness and perfusion. Hand function was evaluated by the Jebsen hand function test and Michigan Hand Function Questionnaire. RESULTS: Vancouver Scar scale showed significantly better scores in the MEBO group than in the conventional skin graft group. Scar thickness and transepidermal water loss were greater in the MEBO treatment group whereas pigmentation value was greater in the conventional skin graft group. There was no significant difference in the hand function between the two groups. CONCLUSION: MEBO application could be an alternative treatment to conventional skin graft treatment in full thickness hand burn wounds. In the future, more studies are yet to come how MEBO treatment may affect the skin condition of the burn injuries.
Burns*
;
Cicatrix*
;
Erythema
;
Hand*
;
Michigan
;
Perfusion
;
Pigmentation
;
Pliability
;
Prospective Studies
;
Surveys and Questionnaires
;
Skin*
;
Transplants*
;
Wounds and Injuries
7.The Potency of Mivacurium during Halothane or Enflurane Anesthesia in Infants and Preschool Children.
Ki Young LEE ; Jeong Uk HAN ; Jung Lyul KIM ; Hyun Woo LEE ; Yang Sik SHIN
Korean Journal of Anesthesiology 1997;33(2):267-271
BACKGROUND: The dose-responses of neuromuscular blocking agents may be influenced by many factors including age and inhalation anesthetics. This study was designed to determine the dose-response relationships of a new, short-acting muscle relaxant, mivacurium during nitrous oxide-halothane or nitrous oxide-enflurane anesthesia in two age groups, infants and 1 to 6 years old preschool children. METHODS: Neuromuscular blockade was monitored by recording the accelerographic activity of the adductor pollicis muscle resulting from supramaximal stimulation at the ulnar nerve at 2 Hz for 2 seconds at 10-second intervals. To estimate dose-response relationships, 24 infants or children of two anesthetic subgroups for each age group received single bolus doses of 45~100 g/kg of mivacurium. The ED50 and ED95 were estimated from linear regression plots of log-dose vs probit of twitch depression. The lag time, onset time and maximal depression of twitch height for the selective medium dose were mesured. RESULTS: The ED50 and ED95 for the infants group were 38.2 and 53.3 g/kg during halothane anesthesia, and 29.8 and 48.6 g/kg during enflurane anesthesia, respectively. And, those for preschool children group were 49.4 and 90.7 g/kg during halothane anesthesia, and 32.3 and 81.4 g/kg during enflurane anesthesia, respectively. There was a parallelism of the dose-response curve between halothane and enflurane anesthesia in either age group. Also, there was statistically significant difference in the maximal twitch depression for the selective medium dose of mivacurium between halothane and enflurane anesthesia in either group. CONCLUSIONS: The potency of mivacurium during enflurane anesthesia is higher than that during halothane anesthesia in infants and preschool children, and during either inhalation anesthesia the dose of mivacurium is less required in infants than preschool children.
Anesthesia*
;
Anesthesia, Inhalation
;
Anesthetics, Inhalation
;
Child
;
Child, Preschool*
;
Depression
;
Enflurane*
;
Halothane*
;
Humans
;
Infant*
;
Linear Models
;
Neuromuscular Blockade
;
Neuromuscular Blocking Agents
;
Ulnar Nerve
8.Misdiagnosis of florid cemento-osseous dysplasia leading to unnecessary root canal treatment: a case report.
Restorative Dentistry & Endodontics 2013;38(3):160-166
This case report demonstrates an unnecessary endodontic treatment of teeth with florid cemento-osseous dysplasia (FCOD) due to a misdiagnosis as periapical pathosis and emphasizes the importance of correct diagnosis to avoid unnecessary treatment. A 30-year-old woman was referred to our institution for apicoectomies of the mandibular left canine and both the lateral incisors. The periapical lesions associated with these teeth had failed to resolve after root canal treatment over a 3-year period. Radiographic examinations revealed multiple lesions on the right canine, the second premolar, and both first molars as well as the anterior region of the mandible. Based on clinical, radiographic and histological evaluations, the patient condition was diagnosed as FCOD. The patient has been monitored for 2 years. To avoid unnecessary invasive treatment, accurate diagnosis is essential before treatment is carried out in managing FCOD.
Apicoectomy
;
Bicuspid
;
Dental Pulp Cavity
;
Diagnostic Errors
;
Female
;
Fibrous Dysplasia of Bone
;
Humans
;
Incisor
;
Mandible
;
Molar
;
Osteomyelitis
;
Periapical Diseases
;
Tooth
9.Forensic application of radiology for individual identification in mass disaster.
Shin Mong KANG ; Hae Kyung LEE ; Deuk Lin CHOI ; Kui Hyang KWON ; Ki Jung KIM
Korean Journal of Legal Medicine 1992;16(1):7-15
No abstract available.
Disasters*
10.Utility of Volume Assessment Using Bioelectrical Impedance Analysis in Critically Ill Patients Receiving Continuous Renal Replacement Therapy: A Prospective Observational Study.
Ki Hyun PARK ; Jung ho SHIN ; Jin Ho HWANG ; Su Hyun KIM
Korean Journal of Critical Care Medicine 2017;32(3):256-264
BACKGROUND: Fluid overload prior to continuous renal replacement therapy (CRRT) is an important prognostic factor. Thus, precise evaluation of fluid status is necessary to treat such patients. In this study, we investigated whether fluid assessment using bioelectrical impedance analysis (BIA) can predict outcomes in critically ill patients requiring CRRT. METHODS: A prospective observational study was performed in patients who were admitted to the intensive care unit and who required CRRT. BIA was conducted before CRRT; then, the ratio of extracellular water to total body water (ECW/TBW) was derived to estimate volume status. RESULTS: A total of 31 patients treated with CRRT were included. There were 18 men (58.1%), and the median age was 67 years (interquartile range, 51 to 78 years). Fourteen patients (45.2%) died within 28 days after CRRT initiation. Patients were divided into 16 with ECW/TBW ≥0.41 and 15 with ECW/TBW <0.41. Survival rate within 28 days was different between the two groups (P = 0.044). Cox regression analysis revealed a relationship between ECW/TBW ≥0.41 and 28-day mortality, but it was not statistically significant (hazard ratio, 3.0; 95% confidence interval, 0.9 to 9.8; P = 0.061). Lastly, the area under the curve of ECW/TBW for 28-day mortality was analyzed. The area under the curve of ECW/TBW was 0.73 (95% confidence interval, 0.54 to 0.92), and this was significant (P = 0.037). CONCLUSIONS: Fluid status can be assessed using BIA in critically ill patients requiring CRRT, and BIA can predict mortality. Further large trials are needed to confirm the usefulness of BIA in critically ill patients.
Body Water
;
Critical Illness*
;
Electric Impedance*
;
Humans
;
Intensive Care Units
;
Male
;
Mortality
;
Observational Study*
;
Prospective Studies*
;
Renal Replacement Therapy*
;
Survival Rate
;
Water