1.A Case of Metastatic Ganglioneuroblastoma.
Ki Ung HONG ; Yun Jung KIM ; Eun Kyung HONG ; Moon Hyang PARK ; Ghee Young JUNG ; Chin Sam RO
Journal of the Korean Pediatric Society 1989;32(1):121-129
No abstract available.
Ganglioneuroblastoma*
3.Multiple brain abscesses treated by extraction of the maxillary molars with chronic apical lesion to remove the source of infection
Ki Hyun JUNG ; Seong Su RO ; Seong Won LEE ; Jae Yoon JEON ; Chang Joo PARK ; Kyung Gyun HWANG
Maxillofacial Plastic and Reconstructive Surgery 2019;41(1):25-
BACKGROUND:
Brain abscess is a life-threatening condition that occurs due to complications during a neurosurgical procedure, direct cranial trauma, or the presence of local or distal infection. Infection in the oral cavity can also be considered a source of brain abscess.CASE PRESENTATION: A 45-year-old male patient was transported with brain abscess in the subcortical white matter. Navigation-guided abscess aspiration and drainage was performed in the right mid-frontal lobe, but the symptoms continued to worsen after the procedure. A panoramic radiograph showed alveolar bone resorption around the maxillary molars. The compromised maxillary molars were extracted under local anesthesia, and antibiotics were applied based on findings from bacterial culture. A brain MRI confirmed that the three brain abscesses in the frontal lobe were reduced in size, and the patient's symptoms began to improve after the extractions.
CONCLUSION
This is a rare case report about multiple uncontrolled brain abscesses treated by removal of infection through the extraction of maxillary molars with odontogenic infection. Untreated odontogenic infection can also be considered a cause of brain abscess. Therefore, it is necessary to recognize the possibility that untreated odontogenic infection can lead to serious systemic inflammatory diseases such as brain abscess. Through a multidisciplinary approach to diagnosis and treatment, physicians should be encouraged to consider odontogenic infections as a potential cause of brain abscesses.
4.Correlation Between Serum Magnesium, Ionized Calcium and Plasma Renin Activity in Hypertensives.
Hyun Seung KIM ; Bum Soo KIM ; Sang Il LEE ; Ki Taek KIM ; Hyang KIM ; Jin Ho KANG ; Man Ho LEE ; Jung Ro PARK
Korean Circulation Journal 2000;30(8):1017-1023
BACKGROUND AND OBJECTIVES: Previous studies reported that sodium and potassium play an important role in the pathogenesis of hypertension. Recently attention has been directed towards a possible role of the divalent cations such as calcium, and magnesium. Plasma renin activity is also known to be related to divalent cations heterogeneously. This study investigated the relationships between serum magnesium and ionized calcium and plasma renin activity. MATERIALS AND METHODS: The subjects consisted of 27 essential hypertensive patients and 25 normotensive controls. Criteria for hypertensive group in this study were systolic blood pressure> or =140mmHg or a diastolic blood pressure > or =90mmHg (JNC-VI, 1997). Inclusion criteria were normal urinalysis, no history of systemic illness, no intake of antihypertensive drugs, and no recent intake of any other medication. We took magnesium-loading test for a reliable method of assessing possible magnesium deficiency. RESULTS: There was no significant difference between two groups in serum Magnesium concentration and other electrolytes and plasma renin activity. There was significantly higher rate in hypertensives than in normotensives in magnesium retention(hypertensive vs. normotensive: 63.56+/-12.21% vs. 38.43+/-11.53%, P<0.001). There was significant differences in ionized calcium between high-renin and low-or normo-renin hypertensives(P<0.001). Plasma renin activity was correlated positively with serum ionized calcium in hypertensives(r=.8147; P<0.001). CONCLUSION: These results suggest that plasma renin activity is a factor that can influence on serum ionized calcium in high-renin hypertensives.
Antihypertensive Agents
;
Blood Pressure
;
Calcium*
;
Cations, Divalent
;
Electrolytes
;
Humans
;
Hypertension
;
Magnesium Deficiency
;
Magnesium*
;
Plasma*
;
Potassium
;
Renin*
;
Sodium
;
Urinalysis
5.Correlation Between Serum Magnesium, Ionized Calcium and Plasma Renin Activity in Hypertensives.
Hyun Seung KIM ; Bum Soo KIM ; Sang Il LEE ; Ki Taek KIM ; Hyang KIM ; Jin Ho KANG ; Man Ho LEE ; Jung Ro PARK
Korean Circulation Journal 2000;30(8):1017-1023
BACKGROUND AND OBJECTIVES: Previous studies reported that sodium and potassium play an important role in the pathogenesis of hypertension. Recently attention has been directed towards a possible role of the divalent cations such as calcium, and magnesium. Plasma renin activity is also known to be related to divalent cations heterogeneously. This study investigated the relationships between serum magnesium and ionized calcium and plasma renin activity. MATERIALS AND METHODS: The subjects consisted of 27 essential hypertensive patients and 25 normotensive controls. Criteria for hypertensive group in this study were systolic blood pressure> or =140mmHg or a diastolic blood pressure > or =90mmHg (JNC-VI, 1997). Inclusion criteria were normal urinalysis, no history of systemic illness, no intake of antihypertensive drugs, and no recent intake of any other medication. We took magnesium-loading test for a reliable method of assessing possible magnesium deficiency. RESULTS: There was no significant difference between two groups in serum Magnesium concentration and other electrolytes and plasma renin activity. There was significantly higher rate in hypertensives than in normotensives in magnesium retention(hypertensive vs. normotensive: 63.56+/-12.21% vs. 38.43+/-11.53%, P<0.001). There was significant differences in ionized calcium between high-renin and low-or normo-renin hypertensives(P<0.001). Plasma renin activity was correlated positively with serum ionized calcium in hypertensives(r=.8147; P<0.001). CONCLUSION: These results suggest that plasma renin activity is a factor that can influence on serum ionized calcium in high-renin hypertensives.
Antihypertensive Agents
;
Blood Pressure
;
Calcium*
;
Cations, Divalent
;
Electrolytes
;
Humans
;
Hypertension
;
Magnesium Deficiency
;
Magnesium*
;
Plasma*
;
Potassium
;
Renin*
;
Sodium
;
Urinalysis
6.A Case of Zosteriform Kaposi's Sarcoma.
Jin Geol JUNG ; Ki Woong RO ; Sang Dai SHIM ; Myung Hwa KIM ; You Chan KIM ; Yong Woo CINN
Korean Journal of Dermatology 2006;44(3):353-355
Kaposi's sarcoma is a neoplastic, vascular tumor involving the skin or internal organs. We report a case of a 72-year-old male who presented with multiple, grouped, purpuric papules, hemorrhagic bullae and nodules showing zosteriform distribution on the sole of his right foot. In our case, as in some of the cases from the literature, the patient was initially misdiagnosed clinically as having herpes zoster. Histopathologic findings revealed a diffuse infiltrate of small blood vessels and slit-like spaces extending through most of the dermis. Many of the spindle-shaped cells expressed factor VIII-related antigen, and human herpes virus 8 (HHV-8) DNA was detected by polymerase chain reaction (PCR) in paraffin-embedded tissue.
Aged
;
Blood Vessels
;
Dermis
;
DNA
;
Foot
;
Herpes Zoster
;
Humans
;
Male
;
Polymerase Chain Reaction
;
Sarcoma, Kaposi*
;
Skin
;
von Willebrand Factor
7.A Case of Zosteriform Kaposi's Sarcoma.
Jin Geol JUNG ; Ki Woong RO ; Sang Dai SHIM ; Myung Hwa KIM ; You Chan KIM ; Yong Woo CINN
Korean Journal of Dermatology 2006;44(3):353-355
Kaposi's sarcoma is a neoplastic, vascular tumor involving the skin or internal organs. We report a case of a 72-year-old male who presented with multiple, grouped, purpuric papules, hemorrhagic bullae and nodules showing zosteriform distribution on the sole of his right foot. In our case, as in some of the cases from the literature, the patient was initially misdiagnosed clinically as having herpes zoster. Histopathologic findings revealed a diffuse infiltrate of small blood vessels and slit-like spaces extending through most of the dermis. Many of the spindle-shaped cells expressed factor VIII-related antigen, and human herpes virus 8 (HHV-8) DNA was detected by polymerase chain reaction (PCR) in paraffin-embedded tissue.
Aged
;
Blood Vessels
;
Dermis
;
DNA
;
Foot
;
Herpes Zoster
;
Humans
;
Male
;
Polymerase Chain Reaction
;
Sarcoma, Kaposi*
;
Skin
;
von Willebrand Factor
8.A Case of a Pigmented Epidermal Cyst Associated with Transepidermal Elimination.
Sang Dai SHIM ; Jin Geol JUNG ; Ki Woong RO ; Myung Hwa KIM ; Yong Woo CINN
Korean Journal of Dermatology 2005;43(8):1139-1141
Transepidermal elimination is a spontaneously-developed phenomenon in certain skin disorders, in which altered connective tissue or foreign material is expelled via the epidermis to the exterior. We report a case of a 60-year-old man with a 1x1 cm sized, black-colored nodule, showing transepidermal elimination, on the right shin. Histological examination revealed a pigmented, epidermal cyst, containing deposition of pigment in its wall and cavity. To the best of our knowledge, no pigmented epidermal cysts have been reported in korea to date.
Connective Tissue
;
Epidermal Cyst*
;
Epidermis
;
Humans
;
Korea
;
Middle Aged
;
Skin
9.Restoration of Wild-Type p53 by Adenovirus-Mediated Gene Transfer May Enhance the Therapeutic Efficacy of Chemotherapy in Human Ovarian Cancer Cells.
Tae Eung KIM ; Yong Wook KIM ; Heung Ki KIM ; Duck Yeong RO ; Jin Woo KIM ; Jae Keun JUNG ; Dirk G KIEBACK ; Sung Eun NAMKOONG
Korean Journal of Gynecologic Oncology and Colposcopy 2001;12(1):23-30
OBJECTIVE: In an effort to develop a more effective therapeutic strategy for ovarian cancer, we examined whether the restoration of the wild-type p53 gene can enhance the therapeutic effect of chemotherapy. METHODS: In this study, Ov-ca-2774 cells, which are known to have p53 point mutation and cisplatin-resistance, were selected and currently used chemotherapeutic agents including cisplatin, carboplatin, paclitaxel, etoposide, topotecan, and doxorubicin were added concurrently or sequentially with adenovirus-mediated p53 gene transfer (Ad5CMV-p53). RESULTS: Transfer of the wild-type p53 cDNA gene into Ov-ca-2774 cells showed 55% cell killing in vitro at a multiplicity of infection (MOI) of 40. Although the combination of carboplatin or paclitaxel followed by p53 gene transfer with an interval of 48 h manifested no enhanced cell killing compared with cells infected with Ad5CMV-p53 alone, the other combinations of chemotherapeutic agents and p53 gene transfer resulted in 15% to 37% further cell killing (P<0.05). Furthermore, p53 gene transfer followed by doxorubicin with an interval of 24 h and concurrent combination of etoposide with p53 gene transfer showed significant difference in cell killing in contrast to the other combination strategies in the respective chemotherapeutic agent exposure groups (P<0.05). CONCLUSION: Our data demonstrated that combination of p53 gene transfer and chemotherapeutic agents had higher cell killing than either of these two modality alone.
Carboplatin
;
Cisplatin
;
DNA, Complementary
;
Doxorubicin
;
Drug Therapy*
;
Etoposide
;
Genes, p53
;
Homicide
;
Humans*
;
Ovarian Neoplasms*
;
Paclitaxel
;
Point Mutation
;
Topotecan
10.Clinical study of Rh negative patients in pregnancy.
Ki Eun LIM ; Chang Young JUNG ; No Bum LEE ; Moon Il PARK ; Soo Hyun CHO ; Sung Ro CHUNG ; Jae Auk LEE ; Soo Sang KIM ; Hyung MOON
Korean Journal of Obstetrics and Gynecology 1992;35(10):1441-1447
No abstract available.
Humans
;
Pregnancy*