No abstract available.
Ganglioneuroblastoma*

No abstract available.
Humans ; Mothers*

BACKGROUND: Brain abscess is a life-threatening condition that occurs due to complications during a neurosurgical procedure, direct cranial trauma, or the presence of local or distal infection. Infection in the oral cavity can also be considered a source of brain abscess.CASE PRESENTATION: A 45-year-old male patient was transported with brain abscess in the subcortical white matter. Navigation-guided abscess aspiration and drainage was performed in the right mid-frontal lobe, but the symptoms continued to worsen after the procedure. A panoramic radiograph showed alveolar bone resorption around the maxillary molars. The compromised maxillary molars were extracted under local anesthesia, and antibiotics were applied based on findings from bacterial culture. A brain MRI confirmed that the three brain abscesses in the frontal lobe were reduced in size, and the patient's symptoms began to improve after the extractions. CONCLUSION This is a rare case report about multiple uncontrolled brain abscesses treated by removal of infection through the extraction of maxillary molars with odontogenic infection. Untreated odontogenic infection can also be considered a cause of brain abscess. Therefore, it is necessary to recognize the possibility that untreated odontogenic infection can lead to serious systemic inflammatory diseases such as brain abscess. Through a multidisciplinary approach to diagnosis and treatment, physicians should be encouraged to consider odontogenic infections as a potential cause of brain abscesses.

A 59-year old man presented with a 0.5 x 0.3 cm-sized area of, pink-colored, dome-shaped papules on the paranasal area. There was no previous history of trauma to the area. Histopathologic diagnosis was consistent with eccrine poroma. We reported a case of eccrine poroma arising on the paranasal area, an unusual location for this condition.
Diagnosis ; Humans ; Middle Aged ; Poroma*

Transepidermal elimination is a spontaneously-developed phenomenon in certain skin disorders, in which altered connective tissue or foreign material is expelled via the epidermis to the exterior. We report a case of a 60-year-old man with a 1x1 cm sized, black-colored nodule, showing transepidermal elimination, on the right shin. Histological examination revealed a pigmented, epidermal cyst, containing deposition of pigment in its wall and cavity. To the best of our knowledge, no pigmented epidermal cysts have been reported in korea to date.
Connective Tissue ; Epidermal Cyst* ; Epidermis ; Humans ; Korea ; Middle Aged ; Skin

No abstract available.
Cystic Adenomatoid Malformation of Lung, Congenital* ; Diagnosis*

A 35-year-old woman with advanced lung cancer, treated with intravenous docetaxel and paclitaxel, developed subungual abscesses and secondary onycholysis involving all the finger nails. Bacterial culture demonstrated the growth of Pseudomonas aeruginosa. We report a case of onycholysis and subungual abscesses in a patient treated with docetaxel and paclitaxel.
Abscess* ; Adult ; Female ; Fingers ; Humans ; Lung Neoplasms ; Onycholysis* ; Paclitaxel ; Pseudomonas aeruginosa

PURPOSE: Patients that had undergone transurethral resection of the prostate (TURP) for benign prostate hyperplasia (BPH) were evaluated to assess the influence of the amount of resected tissue on the symptomatic improvement. MATERIALS AND METHODS: 42 men, with symptomatic BPH that had undergone TURP, were enrolled in this retrospective study. 20 and 22 patients with prostate volumes equal or less 30ml (group I) and greater than 30ml (group II), respectively, were evaluated. The resected tissue weight (RTW) and the resected tissue weight ratio (RTWR) were taken as preoperative parameters. The percent changes in the International Prostate Symptom Score (IPSS) and in the Quality of Life, and the satisfaction score, were used as measures of the symptomatic outcomes. The symptomatic outcomes of the two groups were compared, and the correlations between the RTW and RTWR and the outcomes in each group assessed. RESULTS: All the symptomatic outcomes of group II were more favorable than those of group I. There were significant correlations between the RTW (and RTWR) and all three outcomes in group II, but there were no correlations between groups I and II. CONCLUSIONS: The patients with the smaller prostate volume (equal or less than 30ml in volume) had less symptomatic improvement after TURP, with no benefit in increasing the amount of resected tissue during TURP. It is recommended excessive resection for BPH should be avoided with a small prostate.
Humans ; Hyperplasia* ; Male ; Prostate* ; Prostatic Hyperplasia ; Quality of Life ; Retrospective Studies ; Transurethral Resection of Prostate

No abstract available.

OBJECTIVE: In an effort to develop a more effective therapeutic strategy for ovarian cancer, we examined whether the restoration of the wild-type p53 gene can enhance the therapeutic effect of chemotherapy. METHODS: In this study, Ov-ca-2774 cells, which are known to have p53 point mutation and cisplatin-resistance, were selected and currently used chemotherapeutic agents including cisplatin, carboplatin, paclitaxel, etoposide, topotecan, and doxorubicin were added concurrently or sequentially with adenovirus-mediated p53 gene transfer (Ad5CMV-p53). RESULTS: Transfer of the wild-type p53 cDNA gene into Ov-ca-2774 cells showed 55% cell killing in vitro at a multiplicity of infection (MOI) of 40. Although the combination of carboplatin or paclitaxel followed by p53 gene transfer with an interval of 48 h manifested no enhanced cell killing compared with cells infected with Ad5CMV-p53 alone, the other combinations of chemotherapeutic agents and p53 gene transfer resulted in 15% to 37% further cell killing (P<0.05). Furthermore, p53 gene transfer followed by doxorubicin with an interval of 24 h and concurrent combination of etoposide with p53 gene transfer showed significant difference in cell killing in contrast to the other combination strategies in the respective chemotherapeutic agent exposure groups (P<0.05). CONCLUSION: Our data demonstrated that combination of p53 gene transfer and chemotherapeutic agents had higher cell killing than either of these two modality alone.
Carboplatin ; Cisplatin ; DNA, Complementary ; Doxorubicin ; Drug Therapy* ; Etoposide ; Genes, p53 ; Homicide ; Humans* ; Ovarian Neoplasms* ; Paclitaxel ; Point Mutation ; Topotecan