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1.Experimental study on the antimicrobial effect of hyperbaric oxygentherapy on the microorganisms of the mandibular osteomyelitis inalbino rats.

There are numerous drug interactions related to many psychotropic and cardiovascular medications. Firstly, the principles in predicting drug interactions are discussed. Cytochrome P (CYP) 450 plays a significant role in the metabolism of these drugs that are substrates, inhibitors, or inducers of CYP450 enzymes. The two most significant enzymes are CYP2D6 and CYP3A4. The ability of psychotropic drugs to act as inhibitors for the enzymes may lead to altered efficacy or toxicity of co-administered cardiovascular agents as a substrate for the enzymes. The following is also a review of the known interactions between many commonly prescribed cardiovascular agents and psychotropic drugs. Most beta blockers are metabolized by CYP2D6, which may lead to drug toxicity when they use in combination with potent CYP2D6 inhibitors including bupropion, chlorpromazine, haloperidol, selective serotonin reuptake inhibitors, and quinidine. Concomitant administration of lithium with angiotensin converting enzyme inhibitors, angiotensin receptor blockers, and diuretics may increase serum lithium concentrations and toxicity. Calcium channel blockers and cholesterol lowering agents are subject to interactions with potent inhibitors of CYP3A4, such as amiodarone, diltiazem, fluvoxamine, nefazodone, and verapamil. Prescribing antiarrhythmic drugs in conjunction with medications are known to prolong QT interval and/or inhibitors on a relevant CYP450 enzyme is generally not recommended, or needs watchful monitoring. Digoxin and warfarin also have warrant careful monitoring if co-administered with psychotropic drugs.
Amiodarone ; Angiotensin Receptor Antagonists ; Angiotensin-Converting Enzyme Inhibitors ; Anti-Arrhythmia Agents ; Bupropion ; Calcium Channel Blockers ; Cardiovascular Agents ; Chlorpromazine ; Cholesterol ; Cytochrome P-450 CYP2D6 ; Cytochrome P-450 Enzyme System ; Cytochromes ; Digoxin ; Diltiazem ; Diuretics ; Drug Interactions ; Drug Toxicity ; Fluvoxamine ; Haloperidol ; Lithium ; Psychotropic Drugs ; Quinidine ; Serotonin Uptake Inhibitors ; Triazoles ; Verapamil ; Warfarin

1.Experimental study on the antimicrobial effect of hyperbaric oxygentherapy on the microorganisms of the mandibular osteomyelitis inalbino rats.

2.Multiple, Dissecting Giant Aneurysms in a Childhood: A Case Report.

3.Two Separate Aneurysms on Anterior Communicating Artery: A Case Report.

4.Drug Interactions between Cardiovascular Agents and Psychotropic Drugs.

5.A clinical analysis of intussusception in infants and childrens.

6.Atypical Meningioma in the Fourth Ventricle: Case Report.

7.Aneurysm at the Origin of the Accessory Middle Cerebral Artery : A Case Report.

8.Aneurysm at the Origin of the Accessory Middle Cerebral Artery : A Case Report.

9.Surgery of Parasplenial Arteriovenous Malformation with Preservation of Vision : A Case Report.

10.Surgery of Parasplenial Arteriovenous Malformation with Preservation of Vision : A Case Report.

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