A 42-year-old woman with systemic lupus erythematosus (SLE) has had wide-spread erythemas with some purpuric patches on her trunk and upper extremities during exacerbation of her disease. Biopsy findings from erythematous lesions and purpuric areas revealed the pathology of lupus erythematosus and leukocytoclastic vasculitis (LCV) with immune deposits, respectively. A feature of wide-spread symmetrical erythemas with foci of LCV occurring in this patient is considered to be an unusual presentation.
Adult ; Biopsy ; Erythema* ; Female ; Glycogen Storage Disease Type VI ; Humans ; Lupus Erythematosus, Systemic* ; Pathology ; Upper Extremity ; Vasculitis*

No abstract available.
Photochemotherapy* ; Porokeratosis*

Synthetic progesterones have been used to treat menstrual disorders and to prevent habitual or threatened abortion. Recently, they are increasingly used as a part of assisted reproductive technique(ART) for the infertility related to the luteal insufficiency. Cutaneous reactions related to progesterone are rare and only isolated cases of autoimmune progesterone dermatitis have been described. We report, here in, a case of drug-induced progesterone dermatitis which was proved by positive skin test to intradermal progesterone.
Abortion, Threatened ; Dermatitis* ; Female ; Infertility ; Pregnancy ; Progesterone* ; Skin Tests

Lymphomatous involvement of the gallbladder is rarely identified and manifests mostly as a local involvement of disseminated disease. There have been reported only about 20 primary malignant lymphomas of the gallbladder without involvement of other sites. A 63-year-old woman presented with jaundice, epigastric pain, and weight olss of two months duration. There was no systemic lymphadenopathy elsewhere. Abdominal computed tomograph revealed a focal thickening of the gallbladder wall. The removed gallbladder contained a well circumscribed, 5x3 cm-sized, slightly elevated firm area with accentuated mucosal papillary excrescences near the neck protion. The lesion involved whole thickness of the wall, and was made up of diffuse atypical lymphoid cell infiltrates of variable size accompanying plasmacytoid differentiation in areas. Some large tumor cells were pleomorphic and contained prominent nucleoli. To our knowledge, this is the first case of primary malignant lymphoma of the gallbladder in Korean literature.
Female ; Humans

No abstract available.
Adult* ; Colloids* ; Humans ; Scalp*

No abstract available.
Poroma* ; Warts*

Hypertrophic discoid erythema is a clinical variant of chronic cutaneous lupus erythematosus (CCLE) found most often in association with the more classical lesions of discoid erythemas. We report two cases of CCLE with hypertrophic discoid erythemas occurred on the arms; a rare form of cutaneous lesion of CCLE.
Arm ; Erythema* ; Humans ; Lupus Erythematosus, Cutaneous*

No abstract available.
Ear* ; Pilomatrixoma*

No abstract available.
Carcinoma, Merkel Cell* ; Epidermal Cyst* ; Immunosuppression

BACKGROUND: Packs are viscous preparations that produce a film over the skin surface, thus preventing the evaporation of water and increasing the skin temperature. Because of this occlusive effect, packs can be used as the vehicle to which active pharmacologic agents produce a therapeutic effect. OBJECTIVE: This study aimed to explore the feasibility of pack formulation as a vehicle by comparing percutaneous absorption with ointment formulation. METHODS: After 0.5, 1, 2 and 6 hours of topical applications of 0.05% clobetasol 17-propionate ointment and pack on each forearm of 9 young, healthy male subjects, the amounts of the drug in tape-stripped stratum corneum were assessed using high performance liquid chromatography(HPLC). RESULTS: There was no significant difference with regard to the amount of the drug in tape-stripped stratum corneum between ointment and pack formulations of 0.05% clobetasol 17-propionate. CONCLUSION: Pack formulations delivered similar amount of drugs to the skin compared to ointment formulations, suggesting peel-off type pack can be used as a new vehicle of topical corticosteroids.
Adrenal Cortex Hormones* ; Clobetasol ; Forearm ; Humans ; Male ; Skin ; Skin Absorption* ; Skin Temperature