No abstract available.
Sturge-Weber Syndrome*

Laser photocoagulation is commonly used for the treatment of retinal neo-vascularization in ischemic retinal diseases. Transforming growth factor-beta2 is known to be produced by RPE cells after laser photocoagulation and to be related to both regression of neovascularization and acceleration of preretinal fibrosis. In this study, we investgated the safe extent of laser photocoagulation not promoting the fibrosis by measuring intravitreal TGF-beta2 released following treatment. In gray rabbit eyes, trans pars plana vitrectomies and laser photocoagulations[1/8, 1/4, 1/2 of the fundus]were performed. The each eyeball was enucleated and TGF-beta2 concentration was measured at 12, 24, 72 hours after laser photocoagulation. And fibrotic activity was observed by the subconjunctival injection of fibrocyte and TGF-beta2 [0.1, 1, 10ng/milliliter]. The results were as follows:1. When TGF-beta2 was injected subconjunctivally along with fibrocytes, fibrocytic activity was observed found at the concentration of 1 or 10ng/milliliter of TGF-beta2. 2.The intravitreal concentration of TGF-beta2 after laser photocoagulation to the 1/8, 1/4, 1/2 of fundus area were 0.05, 0.1, 0.2ng/milliliter respectively. From the above results, we suggest to treat limit the area of laser photo-coagulation to 1/8 of fundus area in order to prevent the retinal fibrosis.
Acceleration ; Fibrosis ; Light Coagulation ; Retinal Diseases ; Retinaldehyde* ; Transforming Growth Factor beta2 ; Vitrectomy

Five cases of coronary arteriovenous fistula(CAVF) were diagnosed with coronary arteriography during recent 3 years in Seoul National University Hospital. In one patients, the CAVF was from right coronary artery to left ventricle at posterior aspect. In another, the CAVF was from left circumflex to left atrium. In the remaining three, it was from conal branch of left anterior descending to pulmonary artery. The correct diagnosis for the appropriate treatment of CAVF is important since the incicence of the ischemic coronary heart disease is increasing recently.
Adult* ; Angiography ; Arteriovenous Fistula* ; Coronary Disease ; Coronary Vessels ; Diagnosis ; Heart Atria ; Heart Ventricles ; Humans ; Pulmonary Artery ; Seoul

Lemierre's syndrome is characterized by a rare fulminant condition resulting from primary oropharyngeal infection followed by secondary septic thrombophlebitis of the internal jugular vein and metastatic infection. A forty-year-old man who had been on ventilator due to severe chest trauma, showed severe reddish inflammatory swelling of the right cervical soft tissue and newly developed pneumonia. He went into in septic condition shortly thereafter. Thrombophlebitis with central abscess in the right internal jugular vein was identified by neck CT and MRA(magnetic resonance angiography). Right cervical swelling worsened in spite of clindamycin and heparin therapy. We performed immediate surgery for removal of septic thrombus and resection of internal jugular vein. Patient's septic condition, pneumonia, and local inflammatory reaction were improved within several days after surgery.
Abscess ; Clindamycin ; Heparin ; Jugular Veins ; Lemierre Syndrome* ; Neck ; Pneumonia ; Thorax ; Thrombophlebitis ; Thrombosis ; Ventilators, Mechanical

Aortic dissection after aortic valve replacement(AVR) is rare, but it is considered a definite disease entity. It's risk factors are a dilated ascending aorta(>or=50 mm) at the time of AVR, hypertension, and thin fragile aortic wall. We report the surgical treatment of a patient who had ascending aortic dissection 7 years after having undergone AVR due to aortic regurgitation associated with a dilated ascending aorta(50mm in outer diameter).
Aneurysm, Dissecting ; Aortic Valve Insufficiency ; Aortic Valve* ; Humans ; Hypertension ; Risk Factors

BACKGROUND: To evaluate the efficacy of arterial switch operation for transposition of great arteries, serial echocardiographic studies were performed in 8 patients who underwent the surgery between 1989 and 1998 at Dept. of Thoracic & Cardiovascular Surgery, Yeungnam University Hospital in Daegu City, Korea. MATERIAL AND METHOD: Follow-up period ranged from 6 months to 11 years(average of 4.1 years). Body weight ranged from 2.6kg to 4.8kg, with average of 3.6kg. 5 of 8 patients were preoperatively diagnosed as TGA+VSD, and 3 as TGA+IVS. LV function was evaluated by the measurement of LV shortening fraction, LVSTI, and LVEF. RVSTI was also measured. Postoperative function of valve and growth of great vessels were analyzed by the measurement of PSPGV, valvular regurgitation, LA/AO ratio, root dimension of aorta and pulmonary artery, comparing with the age matched controls, respectively. RESULT: LVEF had an average of 65.0+/-9.03% which is tended to increase serially. LVAOPG had an average of 15.9mmHg. RVPAPG, 27.5mmHg. From the measurement of aortic root dimension of 6 patients at end-systole, aortic root growth was assumed to increase more than the mean value of normal growth. PA root dimension at end-systole showed a similar growth progress when compared with age matched normal controls. Postoperative pulmonic valve regurgitation was noted in 5 of total 8 patients, in which 1 patient who showed grade 2 and 4 showed below grade 1. AR, in 6 patients and all grade 1. Except 1 patient, all the valvular regurgitations were below grade 1, which was presumed to be clinically insignificant. CONCLUSION: LV function after arterial switch operation was maintained relatively well. Mild neoaortic stenosis was noted. Neopulmonary stenosis and regurgitation were less than moderate degree and surgical correction was not deemed to be necessary. Growth progress of aortic root was above normal than controls and PA root growth was similar to the normal controls, postoperatively. However, further change and refinement of surgical technique will decrease the incidence of neopulmonary stenosis and regurgitation.
Aorta ; Arteries* ; Body Weight ; Constriction, Pathologic ; Daegu ; Echocardiography* ; Follow-Up Studies* ; Humans ; Incidence ; Korea ; Pulmonary Artery ; Transposition of Great Vessels

PURPOSE: To compare CT features of gastrointestinal stromal tumors (GIST) with those of lymphomas in the small intestine. MATERIALS AND METHODS: CT findings of 11 pathologically confirmed GIST patients and 10 lymphoma patients were retrospectively reviewed. CT findings were analyzed with regard to location, size, margin, growth patterns, internal character, enhancement, invasion, vascular encasement, lymphadenopathy, intestinal obstruction and ascites. RESULTS:An extraluminal mass was present in 82% (9/11) of the GIST patients versus 30% (3/10) of the lymphoma patients. Circumferential wall thickening was observed in 80% (8/10) of the lymphoma patients (p<.05). Internal necrosis or gas was present in 73% (8/11) of the GIST patients versus 10% (1/10) of the lymphoma patients (p<.05). Inhomogeneous enhancement was observed in 63% (7/11) of the GIST patients compared to homogeneous enhancement in 90% (9/10) of the lymphoma patients (p<.05). Lymphadenopathy was only observed in 80% (8/10) of the lymphoma patients (p<.05). In other findings such as fatty infiltration, ascites and intestinal obstruction there were no statistically significant differences (p>.05). CONCLUSION: Features revealed by CT scans are highly useful in differentiating GIST from lymphoma of the small intestine. Extraluminal growth and internal necrosis or gas are more common in patients with GIST compared with lymphoma. CT features of circumferential wall thickening and associated lymphadenopathy are more common in patients with lymphoma.
Ascites ; Gastrointestinal Stromal Tumors* ; Humans ; Intestinal Obstruction ; Intestine, Small* ; Lymphatic Diseases ; Lymphoma* ; Necrosis ; Retrospective Studies ; Tomography, X-Ray Computed

Statistical observation was made on in-patients in the Department of Urology, Keimyung University Medical College and Hospital, Taegu, Korea, during the period from August 1, 1970 through July 31, 1980. 1. Among 2,798 cases of in-patients, 2,138 cases were male and 660 cases were female with a ratio of 3.2: 1. Most common diseases were ureter stone (14. 8%), bladder tumor (7.1%) and renal tuberculosis (6.4%) in order. 2. Of 2.798 in-patients, operation was done in 2,226 cases. 3. Of 2,226 operation cases, T.U.R.(15. 1%) was the most common operation: nephrectomy(11. 1%). ureterolithotomy (10. 5%) and hydrocelectomy (7. 1%) were performed.
Daegu ; Female ; Humans ; Korea ; Male ; Tuberculosis, Renal ; Ureter ; Urinary Bladder Neoplasms ; Urology*

Xanthogranulomatous prostatitis is a rare inflammatory condition of the prostate. We report a case of xanthogranulomatous prostatitis. An 82-year-old man presented to our emergency department complaining of gross hematuria. A hard, enlarged, non-tender prostate was palpated on digital rectal examination. Urinalysis showed hematuria and pyuria, and the complete blood count (CBC) revealed leukocytosis. The prostate-specific antigen (PSA) level was elevated at 86.8 ng/ml. Computed tomography (CT) showed an enlarged prostate (volume 100 ml) that protruded into the bladder base. In the left lobe of the prostate, a 1.2x1.1-cm abscess was seen. Transurethral resection of the prostate was done. The pathological diagnosis was xanthogranulomatous prostatitis. The natural progression of the disease is unknown because of the paucity of cases and long-term follow-up reports. To evaluate the pathogenesis and long-term features of progression of this disease, more clinical cases should be collected.
Abscess ; Aged, 80 and over ; Blood Cell Count ; Digital Rectal Examination ; Emergencies ; Granuloma ; Hematuria ; Humans ; Leukocytosis ; Prostate ; Prostate-Specific Antigen ; Prostatitis ; Pyuria ; Urinalysis ; Urinary Bladder ; Urinary Tract Infections

Dermatomyositis is a clinical syndrome of unknown etiology characterized by a nonpurulent inflammatory myopathy involving striated skeletal muscle associated with rheumatoid arthritis, or systemic lupus erythematosus, sometimes underlying malignancy. A few cases of acute renal failure due to rhabdomyolysis in dermatomyositis has been reported. But, no case combined with breast cancer have been reported. We experienced a case of acute renal failure due to rhabdomyolysis associated with dermatomyositis. The patient was admitted to the our hospital due to breast cancer. After breast cancer operation, she complained of progressive muscle weakness. The heliotrope rash involved the eyelid, bridge of nose and forehead. And eczematoid dermatitis involved the lower abdomen and both forearm and hands. The laboratory findings revealed LDH 2,944IU/L, CPK 2,244IU/L and SGOT 214IU/L. Serum myoglobin and aldolase were increased, and antinuclear antibody was 1:40(positive, homogenous pattern). Electromyogram revealed myopathic findings compatible with dermatomyositis. Then, the patient developed acute renal failure requring hemodialysis. After acute hemodialysis, acute renal failure resolved. But, the patient died on the 113th hospital day due to sepsis. Here, we report a case of acute renal failure due to nontraumatic rhabdomyolysis associated with dermatomyositis in breast cancer.
Abdomen ; Acute Kidney Injury* ; Antibodies, Antinuclear ; Arthritis, Rheumatoid ; Aspartate Aminotransferases ; Breast Neoplasms* ; Breast* ; Dermatitis ; Dermatomyositis* ; Exanthema ; Eyelids ; Forearm ; Forehead ; Fructose-Bisphosphate Aldolase ; Hand ; Humans ; Lupus Erythematosus, Systemic ; Muscle Weakness ; Muscle, Skeletal ; Myoglobin ; Myositis ; Nose ; Renal Dialysis ; Rhabdomyolysis* ; Sepsis