2.It's clinical analysis and autoantibodies.
Yoo Jung HWANG ; Hong Yoon YANG ; Joong Hwan KIM
Korean Journal of Dermatology 1993;31(5):657-663
BACKGROUND: Vitiligo is riot quite a rare diseasep; it has about 1% prevalence. The cause of vitiligo is not clear, however, in recent studies an autoimmune origin is freqluei itily mentioned. OBJECT: We tried to an lyze some clinical features of vitiligo and relate them with the presence of autoantibodies. MEHTODS: A total of 381 vitiligo patients was included for the analysis of clinical features. A laboratory study included rhumatoid factor, antinuclear antibocoly, antithyroglobulin antibody and antimicrosome antibody. Some 62 patients were examined for opl thmologic changes. RESULTS: One hundred and one(26.5%) of 381 patients exam ned showed at least one of the autoantibodies tested. Twenty nine pateints showed 2 different aitintibodies. The age at aonset of vitiligo in the autoantibody positive group was 6.6 years later than that of the autoantibody negative group. Autoimmune and/or endocrine diseases were more frequinty found among aut.oantibody positive patients. These diseas s included hyperthyroidism, diabetes me litus and alopecia areata. One patient revealed retinal hypoigmentation and showed no autoantibcidics. CONCLUSION: About 9% of vitiligo patients who were autoantiocyte positive had clinical evidence of diseases associated with the autoantibody. However, it is prudent. to xpect that more patients with t.he autoantibody may develop later systemic autoimmune diseases or endocrinopathies. A long term follow-up of these patients seem:, to be very important.
Alopecia Areata
;
Antibodies, Antinuclear
;
Autoantibodies*
;
Autoimmune Diseases
;
Endocrine System Diseases
;
Follow-Up Studies
;
Humans
;
Hyperthyroidism
;
Prevalence
;
Retinaldehyde
;
Riots
;
Vitiligo
3.Acetabular Rebision Using Acetabular Reinforcement Ring and Allograft Impaction.
In Hwan HWANG ; Soon Taek JUNG ; Sun Chul HWANG ; Se Hyun CHO
Journal of the Korean Hip Society 2006;18(1):25-30
Purpose: We wanted to evaluate the clinical and radiologic results of acetabular revision using the acetabular reinforcement ring and also the allograft impaction in the acetabulum having deficient bone stock. Material and Methods: Nineteen hips revision arthroplasty were performed in 18 patients (9 males and 9 females) with using an acetabular reinforcement ring and allograft between July 1993 and December 2003. The patients were followed for an average of 64 months (range: 24-153). The mean age at the time of arthroplasty was 59 years old (range: 34-76). The causes of revision were aseptic loosening of the acetabular component in 16 cases, severe progressive osteolysis around the acetabular component in 2 cases and Girdlestone state after infected total hip arthroplasty in one case. The acetabular deficiency was type II in 5 hips, type III in 13 hips, and type IV in one hip according to the AAOS classification. The clinical results were evaluated using the modified Harris hip score, and the radiologic results were evaluated by assessing the preoperative and serial follow-up radiographs. Results: The mean preoperative Harris hip score of 47 was improved to 86 points at the latest follow-up. Periacetabular osteolysis was found in 2 cases, which did not progress at follow-up. The anatomic hip center was restored after revision arthroplasty (p<0.05). Complications were dislocation in 2 cases, breakage of the hook of the Ganz ring in one case, heterotopic ossification in one case and femoral artery injury in one case. All cases showed stable fixation of the acetabular component and good remodelling of the impacted allograft. There was neither recurrence of dislocation nor progression of the acetabular component loosening on the radiographs. Conclusion: Acetabular revision with acetabular reinforcement ring and allograft impaction showed satisfactory clinical and radiologic results with restoration of the hip center and consolidation of the allograft.
Acetabulum*
;
Allografts*
;
Arthroplasty
;
Arthroplasty, Replacement, Hip
;
Classification
;
Dislocations
;
Femoral Artery
;
Follow-Up Studies
;
Hip
;
Humans
;
Male
;
Ossification, Heterotopic
;
Osteolysis
;
Recurrence
4.A Study on the Relationship between Dietary Patterns and the Subjective Stress Perception of Korean Adult Men: Based on the Korean National Health and Nutrition Examination Survey, 2014∼2016
Jae-Hwan CHOI ; Tae-Hwan JUNG ; Hyo-Jeong HWANG
Journal of the Korean Dietetic Association 2022;28(2):85-98
This study was conducted to identify the major dietary patterns of Korean adult men and to examine the relationship between subjective stress perception and these dietary patterns using data from the 2014∼2016 Korean National Health and Nutrition Examination Survey (KNHANES). Of the 23,080 total subjects, adult men between the ages of 19 and 64 who did not take the questionnaire or answer the questions relating to depression, and cases where the daily energy intake was less than 500 kcal or more than 5,000 kcal in the Food Frequency Questionnaire were excluded. This left a total of 3,464 subjects who were included in the final analysis. We performed a factor analysis based on the yearly mean intake frequency of 41 food groups to identify the major dietary patterns. Three major dietary patterns were identified (factor loading >0.3), including the ‘Healthy pattern’, ‘Processed meat pattern’, and the ‘Alcohol pattern’. The ‘Healthy pattern’ was characterized by higher intake of beans, tofu, vegetable, fish, and fruits. The ‘Processed meat pattern’ was characterized by high consumption of processed meats and instant foods. The ‘Alcohol pattern’ was characterized by a higher intake of alcohol. As a response to the subject's subjective perception of stress, the most answered 'a little' according to age, marital status, occupation, income, residential area, smoking status, drinking status, and exercise status. People whose diets followed the ‘Processed meat’ and ‘Alcohol’ patterns had significantly higher scores on subjective stress perception compared to people following the ’Healthy pattern’.To manage subjective stress, it is more effective to maintain health by relieving stress through a healthy method that combines healthy eating and exercise rather than following an unhealthy diet as characterized by the ‘processed meat’ and ‘alcohol’ dietary patterns.
5.A Clinical Study on Neonatal seizures.
Chong Young PARK ; Myung Kul YUN ; Jung Hwan CHOI ; Yong Seung HWANG ; Chong Ku YUN
Journal of the Korean Pediatric Society 1985;28(3):225-235
No abstract available.
Seizures*
6.Placental Transfer of Anti-H. influenzae Type b Specific IgG and Subclasses.
Soo Hee CHANG ; Moon Hwan LEE ; Pyoung Han HWANG ; Soo Chul CHO ; Jung Soo KIM
Journal of the Korean Pediatric Society 1995;38(12):1638-1644
No abstract available.
Immunoglobulin G*
;
Influenza, Human*
7.Deep Learning for Medical Image Analysis: Applications to Computed Tomography and Magnetic Resonance Imaging.
Kyu Hwan JUNG ; Hyunho PARK ; Woochan HWANG
Hanyang Medical Reviews 2017;37(2):61-70
Recent advances in deep learning have brought many breakthroughs in medical image analysis by providing more robust and consistent tools for the detection, classification and quantification of patterns in medical images. Specifically, analysis of advanced modalities such as computed tomography (CT) and magnetic resonance imaging (MRI) has benefited most from the data-driven nature of deep learning. This is because the need of knowledge and experience-oriented feature engineering process can be circumvented by automatically deriving representative features from the complex high dimensional medical images with respect to the target tasks. In this paper, we will review recent applications of deep learning in the analysis of CT and MR images in a range of tasks and target organs. While most applications are focused on the enhancement of the productivity and accuracy of current diagnostic analysis, we will also introduce some promising applications which will significantly change the current workflow of medical imaging. We will conclude by discussing opportunities and challenges of applying deep learning to advanced imaging and suggest future directions in this domain.
Classification
;
Diagnostic Imaging
;
Efficiency
;
Learning*
;
Magnetic Resonance Imaging*
8.A Case of Lupus Vulgaris Followed by Miliary Tuberculosis.
Soon Nam SOH ; Yoo Jung HWANG ; Jae Hong KIM ; Joong Hwan KIM
Annals of Dermatology 1990;2(2):125-127
No abstract available.
Lupus Vulgaris*
;
Tuberculosis, Miliary*
9.A Case of Linear IgA Bullous Dermatosis.
Yoo Jung HWANG ; Hong Yoon YANG ; Chang Woo LEE ; Joong Hwan KIM
Annals of Dermatology 1993;5(1):51-55
This paper deals with a case of linear IgA bullous dermatosis (LABD). The patient was a 58-year-old woman who had multiple pruritic vesicles on the trunk, buttocks, thighs, tongue and buccal mucosa. A biopsy of a lesion revealed subepidermal vesicles. Direct immunofluorescence examination of the perilesional skin showed a linear deposition of IgA along the basement membrane zone (BMZ). Indirect immunofluorescence examination, using NaCl split skin as substrate, showed antiBMZ IgA antibodies bound only to the epidermal side. The skin lesions responded well to oral dapsone therapy.
Antibodies
;
Basement Membrane
;
Biopsy
;
Buttocks
;
Dapsone
;
Female
;
Fluorescent Antibody Technique, Direct
;
Fluorescent Antibody Technique, Indirect
;
Humans
;
Immunoglobulin A
;
Linear IgA Bullous Dermatosis*
;
Middle Aged
;
Mouth Mucosa
;
Skin
;
Thigh
;
Tongue
10.A Case of Linear IgA Bullous Dermatosis.
Yoo Jung HWANG ; Hong Yoon YANG ; Chang Woo LEE ; Joong Hwan KIM
Annals of Dermatology 1993;5(1):51-55
This paper deals with a case of linear IgA bullous dermatosis (LABD). The patient was a 58-year-old woman who had multiple pruritic vesicles on the trunk, buttocks, thighs, tongue and buccal mucosa. A biopsy of a lesion revealed subepidermal vesicles. Direct immunofluorescence examination of the perilesional skin showed a linear deposition of IgA along the basement membrane zone (BMZ). Indirect immunofluorescence examination, using NaCl split skin as substrate, showed antiBMZ IgA antibodies bound only to the epidermal side. The skin lesions responded well to oral dapsone therapy.
Antibodies
;
Basement Membrane
;
Biopsy
;
Buttocks
;
Dapsone
;
Female
;
Fluorescent Antibody Technique, Direct
;
Fluorescent Antibody Technique, Indirect
;
Humans
;
Immunoglobulin A
;
Linear IgA Bullous Dermatosis*
;
Middle Aged
;
Mouth Mucosa
;
Skin
;
Thigh
;
Tongue