1.Management of prematurity.
Korean Journal of Pediatrics 2008;51(10):1127-1128
No abstract available.
2.Change of Plasma Glucose Levels in Term Neonates during the First 72 hours using the New Reagent Strip Method.
Woong Heum KIM ; Jung Hwan CHOI
Korean Journal of Perinatology 1997;8(3):271-277
Blood glucose levels were measured in 89 healthy term neonates during the first 72 hours using the SureStep, a newly developed reagent test strip method by LifeScan. The blood samples were obtained by heel-stick puncture and blood glucose concentrations were monitored at birth(0), 2, 4, 6, 12, 24, 48, and 72 hours after birth. Mean and standard deviation of their measurement were compared according to postnatal hours and type of delivery. Comparison of significance between mean plasma glucose levels were made with the Wilcoxon rank sum test and significance level of 0.05 was used to determine which pair-wise comparisons were significantly different. The mean plasma glucose concentrations of first 6 hours were significantly lower than those of 12, 24, 48, 72 hours. This finding indicates that plasma glucose stabilization in healthy fullterm neonates can be expected with the feedings. The mean plasma glucose concentration at birth in the neonates of cesarean section (64.5+-8.06 mg/dl) was significantly lower than that of vaginal delivery (80.3+-20.7 mg/dl), but there were no significant differences after 2 hours. This may be due to the difference in prenatal care of obstetric department of Horamae hospital (C/S: midnight NPO and Hartmann solution, V/D: NPO with labor pain and 5% dextrose solution intravenously). In summary, the changes in perinatal care, especially prenatal fluid therapy and time of first feeding should be considered in defining neonatal hypoglycemia. Our data suggest that hypoglycemia should he defined as below 40 mg/dl during the first 6 hours and below 55 mg/dl thereafter.
Blood Glucose*
;
Cesarean Section
;
Female
;
Fluid Therapy
;
Glucose
;
Humans
;
Hypoglycemia
;
Infant, Newborn*
;
Labor Pain
;
Parturition
;
Perinatal Care
;
Plasma*
;
Pregnancy
;
Prenatal Care
;
Punctures
;
Reagent Strips*
3.clinical Observation on Neonatal Necrotizing Enterocolitis(Nec).
Journal of the Korean Pediatric Society 1985;28(5):423-434
No abstract available.
4.A clinical analysis of incisional hernia.
Phil Soon PARK ; Yong Hwan JUNG ; Kun Pil CHOI
Journal of the Korean Surgical Society 1993;44(6):1029-1037
No abstract available.
Hernia*
5.Morphologic Changes of Lung Parenchymal Tissue in Neonatal Rat Pups Under Chronic Hyperoxia.
Beyong Il KIM ; Jung Hwan CHOI ; Chong YUN
Journal of the Korean Pediatric Society 1994;37(8):1055-1064
We studied the effects of chronic hyperoxia (>95% oxygen for 14 days) in change of body weight, wet to dry lung weight ratio, and morphologic changes of lung tissue compared with that of room air (21% oxygen for 14 days) in Sprague-Dawley neonatal rat pups. The results were as follows: 1) In neonatal rat pups exposed to room air (normoxia group), body weight of initial 3 days of neonatal rat pups was 9.18 0.18g, and body weights of developing rat pups exposed to room air for 7, 10, 14 days were 14.07 1.90, 17.00 2.09, 23.07 1.93g respectively. In neonatal rat pups exposed to hyperoxia (hyperoxia group), body weight of initial 3 days of neonatal rat pups was 9.35 0.80 g, and body weights of developing rat pups exposed to hyperoxia for 7, 10, 14 days were 11.06 1.31, 12.64 1.77, 15,41 1.65 g respectively. These results suggest that changes of body weight in developing rat pups were stunted significantly in the hyperoxia group compared with normoxia group during 14days-experiment (p<0.01). 2) No appreciable difference of wet to dry lung weight ratio was noted at initial 3 days of neonatal rat pups between normoxia group and hyperoxia group, but considerably increased wet to dry lung weight ratio was noted significantly at 7 days of exposure in the hyperoxia group compared with the normoxia group (p<0.05). The difference of wet to dry lung weight ratio was not significant at 10, 14 days of exposure between normoxia group and hyperoxia group. These results suggested that relative water content of wet lung was at a peak at 7 days of exposure in hyperoxia group. 3) The lung from developing rat pups exposed to room air for 7 days had many small alveoli and numerous septal buds. However, in the lung from developing rat pups exposed to hyperoxia for 7 days, presence of pink staining material within the lumen of the air spaces (proteinaceous edema fluid) and increased interstitial cellularity due to infiltration by macrophages and neutrophils was observed, and these findings suggested acute exudative lung injury. 4) In most lungs from developing rat pups exposed to room air for 14 days, much increased alveolarization including the secondary septal bud formation was observed. However, in most lungs from developing rat pups exposed to hypeoxia for 14 days, increased septal and interstitial cellularity and thickness and interstitial fibrosis were observed significantly compared with normoxia group (p<0.01). In conclusion we could make a experimental animal model which had similar histopathologic finding of bronchopulmonary dysplasia in human infant and this model will be useful for research of pathogenesis of bronchopulmonary dysplasia.
Animals
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Body Weight
;
Bronchopulmonary Dysplasia
;
Edema
;
Fibrosis
;
Humans
;
Hyperoxia*
;
Infant
;
Infant, Newborn
;
Lung Injury
;
Lung*
;
Macrophages
;
Models, Animal
;
Neutrophils
;
Oxygen
;
Pulmonary Edema
;
Rats*
;
Rats, Sprague-Dawley
6.A clinical study on neonatal bacterial meningitis.
Yong Won PARK ; Jung Hwan CHOI ; Chong Ku YUN
Journal of the Korean Pediatric Society 1991;34(6):763-770
No abstract available.
Humans
;
Infant, Newborn
;
Meningitis, Bacterial*
7.A Clinical Survey of Abdominal Masses in the Neonate.
Beyong Il KIM ; Jung Hwan CHOI ; Chong Ku YUN
Journal of the Korean Pediatric Society 1989;32(7):926-932
No abstract available.
Humans
;
Infant, Newborn*
8.Development of Lung Injury and Change in Hyaluronan of Extracellular Matrix by the Effect of Hyperoxia in Neonatal Rat.
Beyong Il KIM ; Jung Hwan CHOI ; Je G CHI
Journal of the Korean Society of Neonatology 2000;7(2):114-121
No abstract available.
Animals
;
Extracellular Matrix*
;
Hyaluronic Acid*
;
Hyperoxia*
;
Lung Injury*
;
Lung*
;
Rats*
9.Changes of Respiratory Indices and Clinical Response to the Different Modes of Delivery for Administration of Surfactant Replacement Therapy in the Respiratory Distress Syndrome.
Beyng Il KIM ; Jung Hwan CHOI ; Chong Ku YUN
Journal of the Korean Society of Neonatology 1997;4(2):205-216
PURPOSE: Factors affecting the response to surfactant replacement therapy are considered as types of surfactant, and strategies of treatment including prophylactic vs rescue therapy, single vs multiple doses, methods of mechanical ventilation, and modes of surfactant delivery. Among those factors, response to surfactant replacement therapy according to the modes of surfactant delivery was rarely studied in the world. In preterm infants with RDS, we studied the efficacy and adverse effects of surfactant replacernent therapy according to the differences in the modes of surfactant delivery. METHOD: Preterm infant weighing 500-2,500g with RDS who required assisted ventilation were divided into two groups. One group is as follows five fractional doses with five positional changes after removal from ventilator by feeding tube technique. The other group is as follows; two fractional doses with two positional changes by side-port adaptor technique. Of the 30 infants enrolled, 15 were randomly assigned to each group. We compared the respiratory indices, chest radiologic response, clinical outcome after surfactant replacement, and adverse effects during dosing procedure. RESULT: There were no diffrences of patient profile between two groups. There were significant improvernent in FiO2, a/APO2, MAP, OI, and chest radiologic response following surfactant replacement therapy in both groups. No significant differences were noted in the adverse effects during dosing procedure and incidence of complication. CONCLUSION: In initial phase of RDS treatment with surfactant replacement therapy, two fractional doses with two positional changes by side-port adaptor technique improve respiratory indices, radiologic response without dernonstrable harmful effects as five fractional doses with five positional changes after removal from ventilator by feeding tube technique, however two fractional dosing procedure is more recommendable because of #more simple and convenient procedure.
Humans
;
Incidence
;
Infant
;
Infant, Newborn
;
Infant, Premature
;
Respiration, Artificial
;
Thorax
;
Ventilation
;
Ventilators, Mechanical
10.Indomethacin therapy in premature infants with patent ductus arteriosus.
Dug Ha KIM ; Jung Hwan CHOI ; Chong Ku YUN
Journal of the Korean Pediatric Society 1991;34(10):1381-1390
No abstract available.
Ductus Arteriosus, Patent*
;
Humans
;
Indomethacin*
;
Infant, Newborn
;
Infant, Premature*