1.MR findings of paranasal sinus mucocele report of 3 cases.
Sang Hee CHOI ; Seoung Oh YANG ; Sun Seob CHOI ; Kyung Jin NAM ; Yung Il LEE ; Duck Hwan CHUNG ; Jung Hwan BAK ; Lee Seok KIM
Journal of the Korean Radiological Society 1992;28(5):687-691
The signal intensity of paranasal sinus mucocele is highly variable, ranging from high to low on both T1 weighted and T2 weighted sequence, This variation is likely due to the combined effects of decreased free water concentration, cross-linking and polymerization of the macromolecular mucus glycoprotein, and increased viscosity. We have experienced three cases of the paranasal sinus mucocele with different signal intensity on Magnetic Resonance Imaging. We describe MR characteristics of the paranasal sinus mucocele and compare with MR characteristics for other paranasal sinus disease.
Glycoproteins
;
Magnetic Resonance Imaging
;
Mucocele*
;
Mucus
;
Paranasal Sinus Diseases
;
Polymerization
;
Polymers
;
Viscosity
;
Water
2.Myxoid Leiomyosarcoma of the Superior Vena Cava Syndrome.
Ki Hwan JUNG ; Seung Heon LEE ; Byung Gyu KIM ; Hee Sang KONG ; Je Hyeong KIM ; Sang Myeon BAK ; Cheol SHIN ; Jae Jeong SHIM ; Han Gyum KIM ; Kwang Ho IN ; Kyung Ho KANG ; Se Hwa YOO
Tuberculosis and Respiratory Diseases 2001;51(2):173-177
A 38-year-old woman presented with facial edema with neck vein engorgement for about 45 days. Chest roentgenography showed bulging soft tissue opacities in the right superoanterior mediastinum and a lobulated intraluminal mass was noted in the superior vena cava on the venacavogram. The superior vena cava was incised and the tumor located from the junction of the superior vena cava and internal jugular vein to the right atrial inlet was excised. Grossly, the tumor was myxoid or gelatinous in appearance. A combination of microscopic and immunohistochemical features showed myxoid leiomyosarcoma arising from the wall of the superior vena cava.
Adult
;
Bays
;
Edema
;
Female
;
Gelatin
;
Humans
;
Jugular Veins
;
Leiomyosarcoma*
;
Mediastinum
;
Neck
;
Radiography
;
Superior Vena Cava Syndrome*
;
Thorax
;
Veins
;
Vena Cava, Superior*
3.A Case of Cryoglobulinemia-induced Acute Respiratory Distress Syndrome.
Byung Gyu KIM ; Jae Jeong SHIM ; Ki Hwan JUNG ; Jeong Ho SHIN ; Seung Heon LEE ; Hee Sang KONG ; Je Hyeong KIM ; Sang Myeon BAK ; Chol SHIN ; Kwang Ho IN ; Kyung Ho KANG ; Se Hwa YOO
Tuberculosis and Respiratory Diseases 2001;51(2):155-160
Cryoglobulinemia is the presence of globulins in the serum that precipitate on exposure to cold temperatures (cryoglobulins). Pulmonary complications of cryoglobulinemia include interstial infiltration, impaired gas exchange, small airway disease and pleurisy. Only one other acute respiratory distress syndrome(ARDS) case has been described in patients with cryoglobulinemia. A 55-years old man was admitted with dyspnea. He had been diagnosed as being a hepatitis B virus antigen carrier 15 years age. On the first admission, chest radiography showed a bilateral pleural effusion and a patchy infiltration on both lungs. On protein-and immuno-electrophoresis, cryoglobulinemia was confirmed. The patient was treated with corticosteroid and plasmapheresis. Forty-five days after the diagnosis, the patient complained of progressive dyspnea and showed a diffuse bilateral pulmonary infiltration on chest radiography. Despite intensive care with mechanical ventilation, the patient died as consequence of hypoxemia and multiple systemic organ failure. On a pathologic examination of the postmortem lung biopsy, multiple necrotizing vasculitis and increased infiltration of the lymphocytes and monocytes were observed. In conclusion, ARDS developed as a result of pulmonary hemorrhage due to cryoglobulinemia-associated vasculitis.
Anoxia
;
Biopsy
;
Cold Temperature
;
Cryoglobulinemia
;
Diagnosis
;
Dyspnea
;
Globulins
;
Hemorrhage
;
Hepatitis B virus
;
Humans
;
Critical Care
;
Lung
;
Lymphocytes
;
Monocytes
;
Plasmapheresis
;
Pleural Effusion
;
Pleurisy
;
Radiography
;
Respiration, Artificial
;
Respiratory Distress Syndrome, Adult*
;
Thorax
;
Vasculitis
4.Appendiceal Mucocele.
Seung Yeon PARK ; Jung Nam LEE ; Min CHUNG ; Un Gi LEE ; Yeong Don LEE ; Jae Hwan OHO ; Jung Hum BAK ; Yeon Ho PARK ; Hyeon Yeong KIM ; Keon Kuk KIM ; Sang Tae CHOI
Journal of the Korean Surgical Society 2007;72(2):157-161
Appendiceal mucocele is a cystic dilatation of the appendiceal lumen with mucus, which may be caused by either benign or malignant diseases. In this report, five cases of appendiceal mucocele are reported, three of which had a preoperative diagnosis of mucocele, whereas the others were found incidentally during the operation under the diagnosis of intussusception and periappendiceal abscess. All five patients underwent surgical resections, including one ileocecal resection and four right hemicolectomies. Histopathology revealed a mucinous cystadenoma in four cases, and a mucinous cystadenocarcinoma in one. There was no disease-related death during 18 months of follow-up.
Abscess
;
Appendix
;
Cystadenocarcinoma, Mucinous
;
Cystadenoma, Mucinous
;
Diagnosis
;
Dilatation
;
Follow-Up Studies
;
Humans
;
Intussusception
;
Mucocele*
;
Mucus
5.Fanconi's Syndrome Associated with Prolonged Adefovir Dipivoxil Therapy in a Hepatitis B Virus Patient.
Young Kul JUNG ; Jong Eun YEON ; Jong Hwan CHOI ; Chung Ho KIM ; Eun Suk JUNG ; Ji Hoon KIM ; Jong Jae PARK ; Jae Seon KIM ; Young Tae BAK ; Kwan Soo BYUN
Gut and Liver 2010;4(3):389-393
Adefovir dipivoxil (ADV) is commonly used as an antiviral agent in the treatment of chronic hepatitis B or human immunodeficiency virus infection. Nephrotoxicity has been shown to occur at daily dosages of 60-120 mg. Fanconi's syndrome is a generalized dysfunction of the renal proximal tubular cells, which is usually accompanied by complications. Here we report a case of Fanconi's syndrome in a chronic hepatitis B patient who had been treated with a prolonged regimen of ADV at 10 mg/day. A 47-year-old man complained of severe back and chest-wall pain. He had chronic hepatitis B and had been treated with ADV at a daily dose of 10 mg for 38 months. He was hospitalized because of severe bone pain, and laboratory and radiologic findings suggested a diagnosis of Fanconi's syndrome with osteomalacia. After discontinuation of the ADV, he recovered and was discharged from hospital. His laboratory findings had normalized within 2 weeks. This case indicates that Fanconi's syndrome can be acquired by a chronic hepatitis B patient taking ADV at a conventional dosage of 10 mg/day. Therefore, patients treated with long-term ADV should be checked regularly for the occurrence of ADV-induced Fanconi's syndrome.
Adenine
;
Fanconi Syndrome
;
Hepatitis
;
Hepatitis B
;
Hepatitis B virus
;
Hepatitis B, Chronic
;
HIV
;
Humans
;
Middle Aged
;
Organophosphonates
;
Osteomalacia
6.Bone Age Assessment Using Artificial Intelligence in Korean Pediatric Population: A Comparison of Deep-Learning Models Trained With Healthy Chronological and Greulich-Pyle Ages as Labels
Pyeong Hwa KIM ; Hee Mang YOON ; Jeong Rye KIM ; Jae-Yeon HWANG ; Jin-Ho CHOI ; Jisun HWANG ; Jaewon LEE ; Jinkyeong SUNG ; Kyu-Hwan JUNG ; Byeonguk BAE ; Ah Young JUNG ; Young Ah CHO ; Woo Hyun SHIM ; Boram BAK ; Jin Seong LEE
Korean Journal of Radiology 2023;24(11):1151-1163
Objective:
To develop a deep-learning-based bone age prediction model optimized for Korean children and adolescents and evaluate its feasibility by comparing it with a Greulich-Pyle-based deep-learning model.
Materials and Methods:
A convolutional neural network was trained to predict age according to the bone development shown on a hand radiograph (bone age) using 21036 hand radiographs of Korean children and adolescents without known bone development-affecting diseases/conditions obtained between 1998 and 2019 (median age [interquartile range {IQR}], 9 [7–12] years; male:female, 11794:9242) and their chronological ages as labels (Korean model). We constructed 2 separate external datasets consisting of Korean children and adolescents with healthy bone development (Institution 1: n = 343;median age [IQR], 10 [4–15] years; male: female, 183:160; Institution 2: n = 321; median age [IQR], 9 [5–14] years; male:female, 164:157) to test the model performance. The mean absolute error (MAE), root mean square error (RMSE), and proportions of bone age predictions within 6, 12, 18, and 24 months of the reference age (chronological age) were compared between the Korean model and a commercial model (VUNO Med-BoneAge version 1.1; VUNO) trained with Greulich-Pyle-based age as the label (GP-based model).
Results:
Compared with the GP-based model, the Korean model showed a lower RMSE (11.2 vs. 13.8 months; P = 0.004) and MAE (8.2 vs. 10.5 months; P = 0.002), a higher proportion of bone age predictions within 18 months of chronological age (88.3% vs. 82.2%; P = 0.031) for Institution 1, and a lower MAE (9.5 vs. 11.0 months; P = 0.022) and higher proportion of bone age predictions within 6 months (44.5% vs. 36.4%; P = 0.044) for Institution 2.
Conclusion
The Korean model trained using the chronological ages of Korean children and adolescents without known bone development-affecting diseases/conditions as labels performed better in bone age assessment than the GP-based model in the Korean pediatric population. Further validation is required to confirm its accuracy.
7.Endoscopic Treatment of Benign Hypopharyngeal Tumors.
Jong Hwan CHOI ; Jong Jae PARK ; Joong Bae JEE ; Jong Jin HYUN ; Se Yun KIM ; Ji Hyun KIM ; Byung Kyu KIM ; Ji Hoon KIM ; Yun Jung CHANG ; Cheol Hyun KIM ; Youn Suk SEO ; Jin Yong KIM ; Jae Seon KIM ; Young Tae BAK
Korean Journal of Gastrointestinal Endoscopy 2005;31(5):306-310
During endoscopy, most endoscopists insert endoscopes into the esophagus without visual aid in order to minimize the discomfort to patients. However, studies have shown that visual guided insertion imposes little discomfort, is safe and can increase the diagnostic rate of abnormal pathology of the throat. As for the treatment of hypopharyngeal lesions, cases of endoscopic treatment are rare and any guidelines have not been clearly defined yet. However, endoscopic treatment may be feasible in selected cases. Several procedures, such as endoscopic mucosal resection with cap (EMR-C) and saline injection polypectomy can be applied. We experienced seven patients who had benign hypopharyngeal masses that were removed endoscopically without serious complications. Compared to surgical treatment, endoscopic removal of the benign hypopharyngeal tumors does not require general anesthesia; it is simple, less invasive and less costly. Therefore, endoscopy should be regarded as a treatment option. However, further studies are required before widespread application of endoscopic removal for the definitive treatment of hypopharyngeal masses, including malignancies.
Anesthesia, General
;
Audiovisual Aids
;
Endoscopes
;
Endoscopy
;
Esophagus
;
Humans
;
Pathology
;
Pharynx
8.A Case of Synchronous Quadruple Early Gastric Cancer Which was Detected Preoperatively.
Nam Young JO ; Hwi KONG ; Ji Hoon KIM ; Yeon Ho PARK ; Yoon Hong KIM ; Hyo Jung KIM ; Chul Hwan KIM ; Jae Seon KIM ; Young Jae MOK ; Young Tae BAK ; Chang Hong LEE
Korean Journal of Gastrointestinal Endoscopy 2001;23(1):28-31
Early diagnosis of gastric cancer is very important since gastric cancer is one of the leading causes of cancer-mortality in Korea. The incidence of early gastric cancer has increased recently with much advances in diagnostic modalities and increasing concerns about individual health status. The incidence of multiple gastric cancer is also increasing. The number of lesions in cases with multiple gastric cancer is usually 2 or 3, and lesions over 4 sites are rare. The problem in the diagnosis of multiple gastric cancer is the low preoperative detection rate in spite of the recent advances of diagnostic techniques, especially in cases with small flat or elevated lesions. We report a case of a synchronous quadruple early gastric cancer which was preoperatively diagnosed with endoscopy. Of the four lesions, one was depressed (IIc) and the other three were superficial elevated (IIa). All four lesions were well differentiated adenocarcinomas confined to the mucosa.
Adenocarcinoma
;
Diagnosis
;
Early Diagnosis
;
Endoscopy
;
Incidence
;
Korea
;
Mucous Membrane
;
Stomach Neoplasms*
9.A Case of Submucosal Tumor-like Early Gastric Adenocarcinoma Diagnosed by Endoscopic Mucosal Resection.
Se Yune KIM ; Jong Jae PARK ; Yongik CHO ; Jong Hwan CHOI ; Ji Hyun KIM ; Byung Kyu KIM ; Ji Hoon KIM ; Yun Jung CHANG ; Cheol Hyun KIM ; Youn Suk SEO ; Jin Yong KIM ; Jae Seon KIM ; Young Tae BAK
Korean Journal of Gastrointestinal Endoscopy 2005;31(6):404-408
In rare cases, early gastric cancer resembles the endoscopic features of a submucosal tumor (SMT). A correct histological diagnosis is difficult with repeated biopsy specimens because they are covered with normal mucosa. Some features known to suggest malignant SMT include a size greater than 3 to 5 cm, a rapid growth rate, echoheterogeneity and irregular margins on endoscopic ultrasonography (EUS). Various techniques including US-guided biopsy, partial removal by an endoscopic snare excision, as well as EUS with a fine needle aspiration were used to enhance the diagnostic accuracy. We recently experienced a case of early gastric cancer, presenting as a submucosal tumor-like lesion, which was confirmed by endoscopic mucosal resection. We report this case with a review of the relevant literature.
Adenocarcinoma*
;
Biopsy
;
Biopsy, Fine-Needle
;
Diagnosis
;
Endosonography
;
Mucous Membrane
;
SNARE Proteins
;
Stomach Neoplasms
10.Massive bleeding from left colonic arteriovenous malformation in a young patient with ventricular septal defect.
Gil Man JUNG ; Young Tae BAK ; Oh Sang KNOW ; Jeong Heon OH ; Jae Seon KIM ; Jin Ho KIM ; Jeong Hwan KEUM ; Cheol Min PARK ; In Ho CHA ; Kwang Il KIM ; Han Kyeom KIM
The Korean Journal of Internal Medicine 1998;13(1):56-59
Arteriovenous malformation of the gut is well known to have been an important bleeding focus in past ages. We report a young Korean male patient, who had been known to have ventricular septal defect, presenting massive lower gastrointestinal bleeding from an arteriovenous malformation involving a long segment of the left colon. Angiographic, gross and histologic findings are presented and the literature is reviewed.
Adult
;
Arteriovenous Malformations/pathology
;
Arteriovenous Malformations/complications*
;
Colon/blood supply*
;
Gastrointestinal Hemorrhage/etiology*
;
Heart Septal Defects, Ventricular/complications*
;
Human
;
Male