PURPOSE: To evaluate the patterns of tumor shape and to compare tumor volume derived from simple diameter-based ellipsoid measurement with that derived from tracing the entire tumor contour using region of interest (ROI)-based 3D volumetry with respect to the prediction outcome in cervical cancer patients treated with concurrent chemotherapy and radiotherapy. MATERIALS AND METHODS: Magnetic resonance imaging was performed in 98 patients with cervical cancer (stage IB-IIIB). The tumor shape was classified into two categories: ellipsoid and non-ellipsoid shape. ROI-based volumetry was derived from each magnetic resonance slice on the work station. For the diameter-based surrogate "ellipsoid volume," the three orthogonal diameters were measured to calculate volume as an ellipsoid. RESULTS: The more than half of tumor (55.1%) had a non-ellipsoid configuration. The predictions for outcome were consistent between two volume groups, with overall survival of 93.6% and 87.7% for small tumor (<20 mL), 62.9% and 69.1% for intermediate-size tumor (20-39 mL), and 14.5% and 16.7% for large tumors (> or =40 mL) using ROI and diameter based measurement, respectively. Disease-free survival was 93.8% and 90.6% for small tumor, 54.3% and 62.7% for intermediate-size tumor, and 13.7% and 10.3% for large tumor using ROI and diameter based method, respectively. Differences in outcome between size groups were statistically significant, and the differences in outcome predicted by the tumor volume by two different methods. CONCLUSION: Our data suggested that large numbers of cervical cancers are not ellipsoid. However, simple diameter-based tumor volume measurement appears to be useful in comparison with ROI-based volumetry for predicting outcome in cervical cancer patients.
Disease-Free Survival ; Humans ; Magnetic Resonance Imaging ; Magnetic Resonance Spectroscopy ; Magnetics ; Magnets ; Tumor Burden ; Uterine Cervical Neoplasms

No abstract available.
Amlodipine* ; Humans ; Hypertension*

No abstract available.
Doxazosin* ; Hypertension*

No abstract available.
Humans ; Hypercholesterolemia* ; Lovastatin*

Since the time when the lumbar discogram was used as the clinical diagnostic method for the first time in 1952, many problems have been pointed out to this method, and moreover, in presentday tendencies for the diagnostic method, the lumbar discogram is carried on even useless by majority. One of the important reasons is that so many studies for the lumbar discograms have reported so many false positive lumbar discograms at the high ratio. Hower we found a certain usefulness of the lumbar discogram incidental to the operation. The purposes of our operative lumbar discogram are those; 1) to observe the radiological configuration of the lumbar discogram. 2) to measure the amount of the the dye injected into normal and abnormal lumbar discs, especially in our Koreans. 3) for confirmation of the diagnosis when the myelographic finding is suspicious. 4) for confirmation of the Ievel especially when the number of the possible lesion is more than one. We investigated and analyzed the 35 lumbar discograms of 26 patients and compiled the statistics.
Diagnosis ; Humans ; Methods

No abstract available.
Hemorrhoids*

No abstract available.
Nails*

No abstract available.
Biopsy* ; Child* ; Humans

The morphologic unit of the disease process currently referred to as Kaposi's sarcoma consists of a complex growth of vascular channels and mesenchymal cells of various types and in different phases of differentiation. Kaposi's sarcoma, with its characteristic skin lesion, is an entity familiar to the pathologist and dermatologist. This case report represents an unusal bone cortex involvement of Kaposi's sarcoma with skin lesion in a lower extremity, which has survived for 26 years without no specific abnormality in laboratory study and no specific clinical change.
Lower Extremity ; Sarcoma, Kaposi ; Skin

Anterior cervical interbody fusion and posterior lumbar interbody fusion of the Clowards technique is based on those; 1. removal of the painful disc. 2. stabilization of the unstable joint by interbody fusion. This technique has many advantages compared with the others including followings; 1. very simple technique. 2. low morbidity. 3. rapid recovery. 4. no need of the external support device postoperatively. We operated 5 cervical spines and 2 lumbar ones. This is the report of their follow up study in 2 to 2 years.
Follow-Up Studies ; Joints ; Spine