No abstract available.
Mood Disorders* ; Temporal Lobe*

No abstract available.
Mood Disorders* ; Temporal Lobe*

Cerebral Cortex ; Fibrosis ; Humans ; Hyalin ; Joints ; Magnetic Resonance Imaging ; Osteoarthritis ; Temporal Lobe ; Temporomandibular Joint

BACKGROUND/AIMS: A self-report questionnaire is frequently used to measure symptoms reliably and to distinguish patients with functional gastrointestinal disorders (FGIDs) from those with other conditions. We produced and validated a cross-cultural adaptation of the Rome III questionnaire for diagnosis of FGIDs in Korea. METHODS: The Korean version of the Rome III (Rome III-K) questionnaire was developed through structural translational processes. Subsequently, reliability was measured by a test-retest procedure. Convergent validity was evaluated by comparing self-reported questionnaire data with the subsequent completion of the questionnaire by the physician based on an interview and with the clinical diagnosis. Concurrent validation using the validated Korean version of the Short Form-36 Health Survey (SF-36) was adopted to demonstrate discriminant validity. RESULTS: A total of 306 subjects were studied. Test-retest reliability was good, with a median Cronbach's alpha value of 0.83 (range, 0.71-0.97). The degree of agreement between patient-administered and physician-administered questionnaires to diagnose FGIDs was excellent; the kappa index was 0.949 for irritable bowel syndrome, 0.883 for functional dyspepsia and 0.927 for functional heartburn. The physician's clinical diagnosis of functional dyspepsia showed the most marked discrepancy with that based on the self-administered questionnaire. Almost all SF-36 domains were impaired in participants diagnosed with one of these FGIDs according to the Rome III-K. CONCLUSIONS: We developed the Rome III-K questionnaire though structural translational processes, and it revealed good test-retest reliability and satisfactory construct validity. These results suggest that this instrument will be useful for clinical and research assessments in the Korean population.
Dyspepsia ; Gastrointestinal Diseases* ; Health Surveys ; Heartburn ; Humans ; Irritable Bowel Syndrome ; Surveys and Questionnaires*

No abstract available.
Humans*

No abstract available.

OBJECTIVE: To elucidate etiological factors of heterotopic ossification (HO) by evaluating retrospectively if HO is a unique finding following cervical total disc replacement (CTDR) or a finding observable following an anterior cervical interbody fusion (ACIF). METHODS: The authors had selected 87 patients who underwent anterior cervical surgery (TDR or ACIF), and could be followed up more than 24 months. A cervical TDR was performed using a Bryan disc or a ProDisc-C and an ACIF using a stand-alone cage or fibular allograft with a plate and screws system. The presence of HO was determined by observing plain radiography at the last follow up. The relation between HO occurrence and specific preoperative radio-logical findings (osteophyte and calcification of posterior longitudinal ligament (PLL)) at the index level was investigated. RESULTS: Cervical TDR was performed in 40 patients (43 levels) and ACIF in 47 patients (54 levels). At the final radiographs, HO was demonstrated at 27 levels (TDR-Bryan; 8/18, TDR-Prodisc-C; 12/25, ACIF-cage alone; 7/29, and ACIF-plate screw; 0/25). Mean ROM at the last follow-up of each TDR subgroup were 7.8+/-4.7degrees in Bryan, 3.89+/-1.77degrees in Prodisc-C, and it did not correlated with the incidence of HO. Fusion status of ACIF groups was observed as 2 case of grade 1, 6 of grade 2, and 21 of grade 3 in cage alone subgroup, and no case of grade 1, 4 of grade 2, and 21 of grade 3 in plate screw subgroup. Fusion status in ACIF-cage alone subgroup was significantly related to the HO incidence. The preoperative osteophyte at the operated level observed in 27 levels, and HO was demonstrated in 12 levels (TDR-Bryan; 3/5, TDR-Prodisc-C; 2/3, ACIF-cage alone; 7/11, and ACIF-plate screw; 0/8). Preoperative PLL calcification at the operated level was observed 22 levels, and HO was defined at 14 levels (TDR-Bryan; 5/5, TDR-Prodisc-C; 4/5, ACIF-cage alone; 5/7, and ACIF-plate screw; 0/5). The evidence of preoperative osteophyte and PLL calcification showed statistically significant relations to the occurrence of HO. CONCLUSION: HO was observed in both TDR and ACIF groups. HO was more frequently occurred in TDR group regardless of prosthesis type. In ACIF group, only cage alone subgroup showed HO, with relation to fusion status. Preoperative calcification of longitudinal ligaments and osteophyte were strongly related to the occurrence of HO.
Cinnarizine ; Follow-Up Studies ; Humans ; Incidence ; Longitudinal Ligaments ; Ossification of Posterior Longitudinal Ligament ; Ossification, Heterotopic ; Osteophyte ; Prostheses and Implants ; Retrospective Studies ; Total Disc Replacement ; Transplantation, Homologous

The major complications of Meckel's diverticulum(MD) are bleeding, intestinal obstruction, infection, umbilical fistula and perforation. Although the relative incidences vary between authors, bleeding is the most common complication in children. The aim of our study is to show the symptomatic guideline for the diagnosis of the bleeding MD. Eight cases with bleeding MD which were operated upon at the department of Pediatric Surgery, Yeungnam University Hospital from April 1985 to April 2001 were reviewed. Half of the patients were under 2 years of age and all patients were male. All patients were preoperatively diagnosed by previous history of intestinal bleeding (melena, hematochezia) and 99mTc pertechnetate MD scan. Segmental resection and end-to-end anastomosis was performed in 6 patients and diverticulectomy in 2 patients. Heterotropic gastric mucosa was found in 6 patients. Postoperative complication was not observed in any cases. In conclusion, in any male children with obscure intestinal bleeding, especially less than 2 years of age, bleeding MD must be suspected. It seems to us that 99mTc pertechnetate MD scan is a useful tool to diagnose bleeding MD.
Child ; Diagnosis* ; Fistula ; Gastric Mucosa ; Hemorrhage* ; Humans ; Incidence ; Intestinal Obstruction ; Male ; Meckel Diverticulum* ; Postoperative Complications ; Sodium Pertechnetate Tc 99m

BACKGROUND AND OBJECTIVES: Insomnia is the most prevalent sleep disorder in the general population and is considered to be a disorder of hyperarousal. The aim of this study was to measure the psychophysiological responses in insomnia patients using a biofeedback system, and to compare them with results from normal healthy subjects. MATERIALS AND MATHODS: Eighty patients with primary insomnia (35 males and 45 females, average age 49.71 +/- 12.91 years) and 101 normal healthy controls (64 males and 37 females, average age 27.65 +/- 2.77) participated in this study. Electromyography (EMG), heart rate (HR), skin conductance (SC), skin temperature (ST), and respiratory rate (RR) were recorded using a biofeedback system during 5 phases (baseline, stress 1, recovery 1, stress 2, recovery 2) of a stress reactivity test, and average values were calculated. Difference in values between the two groups in each corresponding phase was analyzed with independent t-test, and change in values across phases of the stress reactivity test was analyzed with paired t-test (all two-tailed, p<0.05). RESULTS: Compared to normal controls, insomnia patients had higher EMG in all 5 phases (baseline : 7.72 +/- 3.88 microV vs. 4.89 +/- 1.73 microV, t = -6.06, p<0.001 ; stress 1 : 10.29 +/- 5.16 microV vs. 6.63 +/- 2.48 microV, t = -5.84, p<0.001 ; recovery 1 : 7.87 +/- 3.86 microV vs. 5.17 +/- 2.17 microV, t = -5.61, p<0.001 ; stress 2 : 10.22 +/- 6.07 microV vs. 6.98 +/- 2.98 microV, t = -4.37, p<0.001 ; recovery 2 : 7.88 +/- 4.25 microV vs. 5.17 +/- 1.99 microV, t = -5.27, p<0.001). Change in heart rate across phases of the stress reactivity test were higher in normal controls than in insomnia patients (stress 1-baseline : 6.48 +/- 0.59 vs. 3.77 +/- 0.59, t = 3.22, p = 0.002 ; recovery 1- stress 1 : -5.36 +/- 0.0.59 vs. -3.16 +/- 0.47, t = 2.91, p = 0.004 ; stress 2-recovery 1 : 8.45 +/- 0.61 vs. 4.03 +/- 0.47, t = 5.72, p<0.001 ; recovery 2-stress 2 : -8.56 +/- 0.65 vs. 4.02 +/- 0.51, t = -5.31, p<0.001). CONCLUSION: Psychophysiological profiles of insomnia patients in a stress reactivity test were different from those of normal healthy controls. These results suggest that the sympathetic nervous system is more highly activated in insomnia patients.
Biofeedback, Psychology* ; Electromyography ; Female ; Heart Rate ; Humans ; Male ; Psychophysiology ; Respiratory Rate ; Skin ; Skin Temperature ; Sleep Initiation and Maintenance Disorders* ; Stress, Physiological ; Sympathetic Nervous System

Most childhood intussusceptions are occured by unknown cause, but a few of them have pathologic lead points. We have collected and analyzed cases with pathologic lead points, and compared them with cases without pathological lead points. A retrospective review was performed on 227 patients who were operated on for intussusception in Yeungnam University Hospital from Jan. 1986 to Apr. 1999. We divided them into 2 groups; idiopathic group (209 cases, 92.1%) and pathologic lead points group (18 cases, 7.9%), and compared the characteristics of each group. Intussusceptions were most commonly occurred in patients between 2 to 6 months of age in both groups. Enteroenteric type of intussusception was relatively more frequent in pathologic lead points group than in idiopathic group (p<0.05). The pathologic lead points were veil (10 cases, 52.6%), Meckel's diverticulum (3 cases, 15.8%), lymphoma (3 cases, 15.8%), ectopic pancreas (2 cases, 10.5%), and Henoch-Schonlein purpura (1 case, 5.3%). The rate of bowel resection was 44.4% in pathologic lead points group and 8.6% in idiopathic group (p<0.05). The present study suggests that the sex, age, type, and operation of intussusception behaved somewhat differently between idiopathic group and pathologic lead points group.
Humans ; Intussusception* ; Lymphoma ; Meckel Diverticulum ; Pancreas ; Purpura, Schoenlein-Henoch ; Retrospective Studies