CT has proven useful in diagnosing pancreatic disease. It is well known that CT is a reliable, simple,noninvasive method for detecting pancreatic carcinoma and extension of the pathology. Of 1150 cases studied forabdominal pathology with Varian-360-3 whole body scanner from June 1980 to June 1982, 38 cases were confirmed tobe pancreatic carcinoma clinically or operatively. We reviewed the CT findings of above cases and the results wereas follows; 1. The sex ration was 31 males to 7 females and the greatest number of cases (31.6%) were seen infourth decade. 2. There were enlargement of pancreas in 37 cases (97.4%), peripancreatic fat obliteration in 28cases (73.7%), dilatation of bile duct in 27 cases (71.1%), enlargement of retroperitoneal lymph nodes in 32 cases(84.2%), dilatation of pancreatic duct in 12 cases (31.6%), Thick vessel sign in 10 cases (26.3%), atrophy ofpancreas body and tail in 3 cases (7.9%), and metastasis in 17 cases (44.7%). 3. In 37 cases of enlargement ofpancreas, enlargement of head in 24 cases, enlargement of head and body in 7 cases, enlargement of body in 2cases, enlargement of body and tail in 2 cases, enlargement of tail in 1 case, and diffuse enlargement of pancreasin 1 case, were observed. 4. Associated findings on CT were pleural effusion (5 cases), ascites (4 cases), livercirrhosis(3 cases), splenomegaly (2 cases), gall stones (3 cases), cholecystitis(2 cases), CBD stone (1 case), IHDstone (1 case), Hydronephrosis (2 cases), renal cyst (2 cases), intraabdominal abscess(1 case), and spinetuberculosis(1 case). 5. There were difficulties in diagnosing one case of diffuse enlargement of opancreas withhead cancer, one case of necrotic head cancer similar to pseudocyst, one case of tail cancer associated withabscess and one case of head cancer associated with pseudocyst in lesser sac.
Ascites ; Atrophy ; Bile Ducts ; Dilatation ; Female ; Gallstones ; Head ; Head and Neck Neoplasms ; Humans ; Hydronephrosis ; Lymph Nodes ; Male ; Methods ; Neoplasm Metastasis ; Pancreas ; Pancreatic Diseases ; Pancreatic Ducts ; Pathology ; Peritoneal Cavity ; Pleural Effusion ; Splenomegaly ; Tail

PURPOSE: To evaluate surface configuration of intervertebral disc on three dimensional CT. MATERIALS AND METHODS: Three dimensional surface images reconstructed from CTscans(1 mm thick) of 20discs in 14 healthy adults were reviewed. Disc surface was classified into peripheral and central zones in contact with consecutive peripheral ring and central endplate. Local irregularity incidence, pattern in radial, concentric, or mixed form, size, location, and extension were observed. Incidence and severity ranges in 4 grades of general irregularity, and peripheral width relative to central radius were evaluated. RESULTS: Normal disc mostly showed smooth surface with few display of small local irregularity(6/20) which was mainly radial in pattern(4/5), posterolaterally located(4/6), and confined within peripheral zone(5/6). General irregularity displayed(5/20) was all grade I and peripheral width was 0.82 of central radius. CONCLUSION: Normal disc shows smooth surface but few may display small local irregularity maybe due to very early degenerative change.
Adult ; Humans ; Incidence ; Intervertebral Disc* ; Radius

No abstract available.

PURPOSE: Kimura's disease is an inflammatory condition of unknown etiology which usually occurs in salivary glands and cervical lymph nodes. This study was undertaken to evaluate the radiologic characteristics of Kimura's disease using CT and MRI. MATERIALS & METHODS: We evaluated CT & MR of 10 patients with histologically proved Kimura's disease in the head and neck. Six males and four females between 16 and 58 years old (mean age, 37.6 years) were included. Contrast enhanced CT scan was performed in all, and spin-echo MRI was performed in 2 patients. RESULTS: Both CT and MRI demonstrated the distinctive sites of involvement that were major salivary glands (4 cases) and lacrimal gland (1 case), periglandular soft tissue (8 cases), and cervical lymph nodes (8 cases). Majority of soft tissue lesions were ill-defined with infiltration to adjacent fascial planes, but nodal lesions were relatively well-defined and homogenous. The lesions were iso-intense on Tl-weighted image and hyper-intense on T2-weighted image. All but a few nodal lesions showed variable degree of contrast enhancement on CT and MRI. CONCLUSION: In diagnosis of Kimura's disease, CT & MRI of head & neck, especially salivary glands, are useful. In cases of recurrent periglandular soft tissue mass with contrast-enhancing cervical lymphadenopathy in adult patients, Kimura's disease should be included in the differential diagnosis.
Adult ; Diagnosis ; Diagnosis, Differential ; Female ; Head* ; Humans ; Lacrimal Apparatus ; Lymph Nodes ; Lymphatic Diseases ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Neck* ; Salivary Glands ; Tomography, X-Ray Computed

From Jan. 1983 to June 1984 in Yonsei University Medical College 17 patients received curative resectivesurgery due to bronchogenic carcinoma. The following results were obtained by comparing the CT findings to theoperative and histological findings of those patients. 1. The histological types of 17 cases of bronchogeniccarcinoma were squamous cell Ca. 8 cases, adenocarcinoma 7 cases, and undifferentiated Ca. 2 cases. The both ofthe undifferentiated type were confirmed by post operative histological study. 2. The lesions showing falsepositivity of mediastinal invasion are enlarged but have well circumscribed margins and separated lymph nodes. 3.In contrast, the prediction of hilar infiltration by CT gave only 25% sensitivity, 77.8% specificity and 52.9%accuracy. 4. For the clinical staging done by CT, only 47.1% were in accordance with the surgical staging. 5.However, CT is useful in selecting the patients who need invasive staging before abandoning curative resection andin suggesting the type of invasive staging according to the location of the lesion.
Adenocarcinoma ; Carcinoma, Bronchogenic ; Epithelial Cells ; Humans ; Lymph Nodes ; Sensitivity and Specificity

This paper contains the results of clinical and neuroradiologic studies in 9 cases of histopathologicallyverified intracranial cavernous hemangiomas. The most common clinical presentations were focal seizure andheadache which were accompained by focal neurologic deficits. Skull films revealed abnormality in 3 cases andcerbral angiography revealed an avascular area in 8 cases, but both were of little diagnostic significance. CTusually demonstrated a hyperdense, cystic and calcified lesion without significant mass effect, and mild degereeof tubular or ring like enhancement after contrast injection. The follow-up CT findings in 4 cases over a 6-monthperiod were compatible to repeated minute hemorrhage and resolution. The above clinical and CT findings and , ifpossible, repeated CT could suggest the diagnosis of cavernous hemangioma and provide the proper management,including the avoidance of unnecessory radiation therapy and biopsy related complications.
Angiography ; Biopsy ; Diagnosis ; Follow-Up Studies ; Hemangioma, Cavernous ; Hemorrhage ; Neurologic Manifestations ; Seizures ; Skull

Authors retrospectively analized the CT findings of mediastinal lesions in surgically or clinically confirmed 37 cases at kosin Medical College during the recent 4 years from Sept. 1979 to Aug. 1983. 1. Among 37 cases, malignant lymphoma were 7 cases, thymoma and vascular lesion or anomaly were 5 cases respectively, benign teratoma and tuberculous mediastinal lymphadentis and neurogenic tumor were 4 cases respectively. pericardial cyst were 2 cases, bronchogenic cyst, non-specific cyst, pancreatic pseudocyst, mesothelioma, Bochdalek hernia was 1 case respectively. 2. The sex ratio between male and female was about 1:1 and the majority of the patients with malignant lymphoma and teratoma was under 20 years old. 3. CT findings of the each mediastinal lesion. 1) Primary mediastinal malignant lymphoma. (1) A large, matted, continuous and midline-crossing mass was observed in the superior and the anterior mediastinums in all cases. (2) In 3 cases, irregular lower densities were seen in the center of the mass, representing the tumor necrosis. (3) CT was also able to show invovlement of other mediastinal lymph nodes and adjacent structures such as pleura, anterior chest wall and lung parenchyma. (4) Involving pleura,homogeneous band-like shadows were seen along the pleura, appearing denser than the associated pleural effusion.(5) Involving lung parenchyma, irregular-shaped nodules and band-llike densities were seen along the courses ofthe bronchi and the vessels. 2) Thyoma. (1) A discrete, soft tissue mass was seen in the superior and the anterior mediastinums(mainly posterior to manubrium and anterior to aortic arch) replacing the normal mediastinal fat. (2)In benign thymoma, the margin of the mass was smooth and the normal fat plane between the mass and the vascular structures was well preserved, but invasive thymoma showed obliteration of the normal fat plane, irregular and ragged tumor-lung interface, and irregular thickening of pleura and pericardium by tumor implantation to thesestructures. (3) The tumors spreaded to only one side of the chest cavity. 3) Teratoma (1) A discrete and smooth marginated mass was seen in anterior mediastinum and it has three or more of different tissue densities among fat,water, soft tissue and calcific densities. (2) 3 cases of teratomas showed the characteristic, thick-walled cystic appearances.
Bronchi ; Bronchogenic Cyst ; Female ; Hernia ; Humans ; Lung ; Lymph Nodes ; Lymphoma ; Male ; Manubrium ; Mediastinal Cyst ; Mediastinum ; Mesothelioma ; Necrosis ; Pancreatic Cyst ; Pericardium ; Pleura ; Retrospective Studies ; Sex Ratio ; Teratoma ; Thoracic Wall ; Thorax ; Thymoma

The computed tomographic findings in 5 patients with the central neurofibromatosis were reviewed. Atypical choroid plexus calcification was evident in 3 of 5 patients in the anterior half of lateral ventricle, foramen of Monro and third ventricle. The cause of this abnormal calcification is unknown yet, but it may have the diagnostic significance for central neurofibromatosis.
Cerebral Ventricles ; Choroid Plexus* ; Choroid* ; Humans ; Lateral Ventricles ; Neurofibromatosis 2* ; Third Ventricle

After bone damage of the fetal rat femurs induced by administrating cyclophosphamide(CP),(1/8 LD50) to the pregnant rat on 13th day of gestation, the effects of serum and ascorbic acid on the repair process of the bone during organ culture were studied, histologically and scanning electron microscopically. CP-damaged fetal femurs harvested at 20 days of gestation were cultured fro 2, 5 and 7 days in the waymouth media(WM) with or without fetal bovine serum(FBS) and ascorbic acid, and were observed with light microscope and JSM-35C scanning electron microscope. The results were as follows:1. CP-damaged bone tissue cultured in WM with 10% FBS showed relatively enhanced activities in the differentiation of chondrocytes and ossificstion as compared to that cultured in WM. 2. CP-damaged bone tissue cultured in WM with 10% FBS and 100µg/ml ascorbic acid, showed increase in the length of the bone marrow cavity, and active formation of new osteoid and collagen bundles. 3. The bone tissues cultured in WM with 10% FBS and 400µg/ml ascorbic acid revealed active deposition of bone matrix, thickening of periosteum and marked elongation of the bone marrow cavity. 4. Bone trabeculae of CP-damaged femurs cultured for 2 days in WM showed poor cell proliferation and insignificant bone matix formation. 5. The number of new cells and the amount of the collagen fibrils increased on the bone trabeculae of the bone cultured in WM with 10% FBS as compared to that cultured in WM and this increase was enhanced as the culture time progressed. 6. A remarkable increase was noted in the number of cells and collagen fibrils in the bone tissues cultured in WM with 10% FBS and ascorbic acid than in those cultured in WM with 10% FBS. 7. The number of the spherules formed by cellular component with collagen fibrils is more numerous than that formed by calcospherites associated with collagen fibrils.
Animals ; Ascorbic Acid ; Bone and Bones ; Bone Marrow ; Bone Matrix ; Cell Proliferation ; Chondrocytes ; Collagen ; Cyclophosphamide ; Femur ; In Vitro Techniques ; Organ Culture Techniques ; Periosteum ; Pregnancy ; Rats

PURPOSE: The purpose of this study is to describe Magnetic Resonance(MR) findings of two epidural cavernous malformations of the spine. MATERIALS AND METHODS: MR imaging was performed in 2 patients(29-year-old man and 54-year-old woman). Sagittal T1 -, T2-weighted images and Gadolinium (Gd)-enhanced axial and sagittal images were acquired. Two patients had surgery and MR findings were compared with surgical and histopathological findings. RESULTS: MR imaging showed high- and low-signal intensity components of these lesions that were characteristic of an epidural cavernous malformation in one case. The other case showed a high signal intensity on T2- and strong enhancement on Gd-enhanced T1 -weighted images. We think that the former may be due to mixed subacute and chronic hemorrhage and the latter may be due to blood within the endotheliumlined sinusolds without hemorrhage. CONCLUSION: These findings were well correlated with the surgical and histo-pathological findings of cavernous malformation.
Gadolinium ; Hemorrhage ; Humans ; Magnetic Resonance Imaging* ; Middle Aged ; Spine*