1.Experimental Study of Heterograft Method on the Healing Process of Long Bone Defect in Rabbits.
Sang Won PARK ; Oh Yong KANG ; Dae Cheol JUNG ; Dae Gon WIE
The Journal of the Korean Orthopaedic Association 1997;32(2):449-456
Bone grafts are used in the repair of segmental bone loss caused by severe trauma, bone tumors and infection, and to enhance bone healing in ununited fractures. Autograft is the most frequently used and the most effective method, but because of inadquate supply and additional operative morbidity, allograft or heterograft could be used. Heterograft has been shown to be poorly tolerated by the host and ineffective in providing an osteogenic system. The objective of this study is to observe healing process of a segmental defect of long bone following to heterograft, and to compare the difference of histologic process between autograft and hetero graft. Twenty-four white rabbits weighing 1,000 to 2,000 grams were used for the experiment. A segment measuring three times the diameter of the ulna shaft (1.5 to 2cm) of rabbit was resected with its periosteum. Twenty-four white rabbit were divided into three groups (control, autograft, heterograft group) according to graft methods, each group comprising of eight rabbits. The animals were sacrificed at 2, 4, 8 and 12 weeks after the experimental procedures and were periodically evaluated by radiographs and histology. The obtained results were as follows: 1. The results of the radiological evaluation showed that no ungrafted ulnar defects (control group) healed. In the heterograft group, partial union was observed from 8 weeks and complete union was obtained on 12 weeks. In the autograft group, partial union was observed on 2 weeks and complete union was obtained on 4 weeks. 2. The results from histological examination showed that the ungrafted ulnae did not heal across the defect but some immature trabeculae were founded on the edges of the defect. In the heterograft group, immature trabeculae were appeared from 4 weeks and defects were substituted with mature trabeculae on 12 weeks. In autograft group, defects were substituted with immature trabeculae on 2 weeks and with mature trabeculae on 4 weeks. As seen in the results of the experiment, union could be obtained with the heterograft, but needed more long time than autograft. Though the autograft is the most effective graft method in bone defect or non-union, above results suggest the heterograft as the alternative method in the treatment of large bone defect, in a multioperated patient, or in the children or the elderly, combined with autograft or alone.
Aged
;
Allografts
;
Animals
;
Autografts
;
Child
;
Fractures, Ununited
;
Heterografts*
;
Humans
;
Periosteum
;
Rabbits*
;
Transplants
;
Ulna
2.Coil Embolization of Rasmussen Aneurysm Diagnosed by Helical CT: A Case Report Dae .
Dae Sik RYU ; Seung Mun JUNG ; Jung Hyen LEE ; Deok Hee LEE ; Bock Hyen JUNG ; Wann PARK ; Man Soo PARK
Journal of the Korean Radiological Society 2001;44(5):565-569
We report a case of Rasmussen aneurysm diagnosed by helical CT that well shows vascular imaging. Coil embolization of Rasmussen aneurysm stopped the bleeding successfully.
Aneurysm*
;
Embolization, Therapeutic*
;
Hemorrhage
;
Tomography, Spiral Computed*
3.Percutaneous Transluminal Angioplasty with Palmaz-Schatz Stent in the Carotid Artery Stenosis.
Sang Sig CHEONG ; Seong Wook PARK ; Seung Jung PARK ; Dae Chul SUH ; Myoung Chong LEE
Korean Circulation Journal 1996;26(4):921-925
Carotid endarterectomy is superior to medical treatment in preventing secondary stroke in patients with symptomatic high grade carotid stenosis. Transluminal angioplasty is a promising procedure as an alternative treatment for these patients. We report two cases of carotid angioplasty with Palmaz-Schatz stent in patients with carotid artery occlusive disease. One patient presented with decreased right visual acuity because of retinal arterial embolism. The angiogram demonstrated a discrete tight stenosis of right internal carotid artery carotid stenting with Palmaz-Schatz coronary stent was performed without any significant complications. The other patient presented with recurrent episodes of cerebral infarction, for which he had undergone left carotid erdarterectomy 3-years ago. The carotid angiogram demonstrated tight stenoses of both internal carotid arteries. Carotid artery stenting was performed at left and right internal carotid arteries without any complications. We suggest that stenting may be an effective and safe therapeutic alternative to surgical treatment in some selected patients with carotid artery occlusive disease.
Angioplasty*
;
Carotid Arteries*
;
Carotid Artery, Internal
;
Carotid Stenosis*
;
Cerebral Infarction
;
Constriction, Pathologic
;
Embolism
;
Endarterectomy, Carotid
;
Humans
;
Retinaldehyde
;
Stents*
;
Stroke
;
Visual Acuity
4.A Case of Idiopathic Hypertrophic Cranial Pachymeningitis Associated with Tolosa-Hunt Syndrome.
Eun Joo KIM ; Kyung Pil PARK ; Dae Seong KIM ; Dae Soo JUNG ; Kyu Hyun PARK ; Dong June PARK ; Boo Sup OUM
Journal of the Korean Neurological Association 2001;19(1):56-59
Idiopathic hypertrophic cranial pachymeningitis (IHCP) is a rare disease, which causes chronic progressive inflammation and thickening of the basal dura mater and produces multiple cranial neuropathies, headache, ataxia, and seizure. A 40 year-old man presented with a continuous, diffuse, dull headache with left periorbital pain, exophthalmos, ptosis and loss of visual perception. Brain MRI revealed thickened, highly enhanced pachymeninges in all supratentorial areas in association with the left cavernous sinus. A subsequent meningeal biopsy showed non-specific chronic inflammations of the pachymeninges. The patient dramatically responded to steroid therapy. To our knowledge, this is an extremely rare case of IHCP associated with Tolosa-Hunt syndrome. (J Korean Neurol Assoc 19(1):56~59, 2001
Adult
;
Ataxia
;
Biopsy
;
Brain
;
Cavernous Sinus
;
Cranial Nerve Diseases
;
Dura Mater
;
Exophthalmos
;
Headache
;
Humans
;
Inflammation
;
Magnetic Resonance Imaging
;
Meningitis*
;
Rare Diseases
;
Seizures
;
Tolosa-Hunt Syndrome*
;
Visual Perception
5.Comparison of F-18 FDG Radioacitivity to Determine Accurate Dose Calibrator Activity Measurements.
Gye Hwan JIN ; Dae Cheol KWEON ; Ki Baek OH ; Hoon Hee PARK ; Jung Yul KIM ; Min Soo PARK ; Dae Sung PARK
Korean Journal of Medical Physics 2009;20(3):159-166
Obviously, the administration of the prescribed amount of activity to the patient requires proper operation of the dose calibrator, which shall be verified by implementing the required quality control on the instrument. This investigation examined the accuracy and precision of dose calibrator activity measurement of the radiopharmaceutical F-18 FDG. To investigate the status of the nuclear medicine centers in Korea for the performance of dose calibrators, 10 centers providing PET/CT system services in Korea were inspected in 2008. We measured accuracy and precision in 10 equipments in consideration of PET/CT model, installation area, and installation time. According to the results of comparative analysis of 10 dose calibrators used to measure radioactivity of F-18 FDG, accuracy was -5.00~4.50% and precision was 0.05~0.45%, satisfying the international standards, which are accuracy +/-10% and precision +/-5%. This study demonstrated that, for accurate measurements, no adjustment is necessary for a dose calibrator setting when measuring different dose calibrators of F-18 FDG activity prescriptions.
Humans
;
Korea
;
Nuclear Medicine
;
Quality Control
;
Radioactivity
6.Comparison of F-18 FDG Radioacitivity to Determine Accurate Dose Calibrator Activity Measurements.
Gye Hwan JIN ; Dae Cheol KWEON ; Ki Baek OH ; Hoon Hee PARK ; Jung Yul KIM ; Min Soo PARK ; Dae Sung PARK
Korean Journal of Medical Physics 2009;20(3):159-166
Obviously, the administration of the prescribed amount of activity to the patient requires proper operation of the dose calibrator, which shall be verified by implementing the required quality control on the instrument. This investigation examined the accuracy and precision of dose calibrator activity measurement of the radiopharmaceutical F-18 FDG. To investigate the status of the nuclear medicine centers in Korea for the performance of dose calibrators, 10 centers providing PET/CT system services in Korea were inspected in 2008. We measured accuracy and precision in 10 equipments in consideration of PET/CT model, installation area, and installation time. According to the results of comparative analysis of 10 dose calibrators used to measure radioactivity of F-18 FDG, accuracy was -5.00~4.50% and precision was 0.05~0.45%, satisfying the international standards, which are accuracy +/-10% and precision +/-5%. This study demonstrated that, for accurate measurements, no adjustment is necessary for a dose calibrator setting when measuring different dose calibrators of F-18 FDG activity prescriptions.
Humans
;
Korea
;
Nuclear Medicine
;
Quality Control
;
Radioactivity
7.Surgical complications of CAPD.
Chan Dae PARK ; Jin Young KWAK ; Ho Jung KIM ; Chan Hyun PARK ; Chong Myung KANG ; Han Chul PARK
The Journal of the Korean Society for Transplantation 1992;6(1):127-132
No abstract available.
Peritoneal Dialysis, Continuous Ambulatory*
8.Temporomandibular joint bony ankylosis following postoperative radiotherapy for maxillary cancer.
Yeung Joon LEE ; Chi Hee PARK ; Dae Won KANG ; Jye Jung SOH ; Jye Jynn ANN
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1993;19(4):533-539
No abstract available.
Ankylosis*
;
Radiotherapy*
;
Temporomandibular Joint*
9.Aggressive Osteoblastoma.
Yong Koo PARK ; Hyung Bae MOON ; Dong Kyuen LEE ; Dae Moo SHIM ; Jung Dal LEE
Korean Journal of Pathology 1986;20(2):235-239
Osteoblastomas were originally thought to be lesions that could be controlled with minimal local therapy, including curettage. However, at least some of the osteoblastomas with an unexpectedly active clinical course had histologic features which differed from ordinary osteoblastomas, and the term aggressive osteoblastoma was given to these lesions. In the aggressive osteoblastoma the osteoblasts are cytologically atypical. In addition, the well organized trabecular patterns of typical osteoblastoma is partly lacking, especially in the areas that are rich in atypical osteoblasts. The case report deals a case of aggressive osteoblastoma of the left iliac wing in a 44 year old male. The interesting radiologic manifestationa(plain x-ray CAT and radionuclide bone scan) and characteristic histologic findings are presented along with review of pertinent literatures.
10.Spinal Cord Infarction following Spine Surgery in the Patient with Vertebral Bursting Fracture : A case report.
Sang Jin PARK ; Hyun Chul JUNG ; Dae Lim JEE
Korean Journal of Anesthesiology 2007;52(4):471-474
Spinal cord infarction as a complication of spine surgery occurs rarely. Herein, a case of spinal cord infarction, which developed in a 69 year old woman following posterior decompression and internal fixation for a T11 bursting fracture, is descirbed. The anesthetic induction and intraoperative course were uneventful, except at the end of the procedure, where her blood pressure suddenly dropped from 130/90 to 90/60 mmHg. The patient was aggressively treated with a transfusion and vasopressor, the blood pressure then returned to its usual value within 10 minutes. However, during a physical examination in the recovery room, the patient was found to have flaccid lower limbs, with impaired sensory function below the T8 level. Her cord diameter had increased, and a high signal lesion was observed within the thoracic spinal cord, from T9 to T12 level on T2-weighted MR images, which was diagnosing as a spinal cord infarction, was and showed no improvement despite the immediate and aggressive treatment.
Aged
;
Blood Pressure
;
Decompression
;
Female
;
Humans
;
Infarction*
;
Lower Extremity
;
Physical Examination
;
Recovery Room
;
Sensation
;
Spinal Cord*
;
Spine*