No abstract available.
Apoptosis* ; Cell Line* ; Colon* ; Colonic Neoplasms* ; Etoposide*

No abstract available.

Chronic prostatitis has various symptoms and many problems in management. Recently a lipidosterolic extract of Serenoa Repens, Permixon has been reported to reveal potential antiandrogenic and anti inflammatory activities on prostate. Then we used Permixon on chronic prostatitis and following results were obtained. Permixon is administered orally in dose of 160mg., b.i.d. for 60 days in 31 cases of chronic prostatitis in 1st group, Permixon 160mg, with Cipro-floxacin 500mg, b.i.d. in 35 cases in 2nd group and Placebo 2 tablets, b.i.d. in 30 cases in 3rd group. In 1st group 36 cases(77.4%) were improved, 29 cases(82.8%) in 2nd group and 7 cases (23.3 %) of 3rd group were improved. Permixon is an effective drug in chronic prostatitis and there was no changes in laboratory findings and negligible side effects were noticed
Prostate ; Prostatitis* ; Serenoa* ; Tablets

PURPOSE: To evaluate the efficacy of combined treatment of metallic biliary stent placement and radiotherapy in malignant biliary obstruction. MATERIALS AND METHODS: Between January 1992 and February 1994, 22 patients with malignant biliary obstruction were treated with metallic biliary stent placement and radiotherapy. The causes of the obstruction included cholangiocarcinoma(n=14), gallbladder carcinoma(n=4), colon cancer(n=2), pancreatic head cancer (n=1), and stomach cancer(n=1). According to the sites of obstruction level, patient were divided into 2 groups; hilar obstruction(n=18) and common bile duct obstruction(n=4). The patients received dose of 45 Gray/18 fraction by external radiotherapy and 20Gy/8f by high dose rate brachytherapy with iridium--192 source through percutaneous transhepatic biliary drainage(PTBD) catheter. The duration of stent patency after placement, survival period and survival rate by Kaplan Meier method were calculated in dead and alive patients, respectively. RESULTS: In all 22 patients, the duration of stent patency was 5.5(1.3--18.5)months. Survival periods after stent placement and PTBD were 5.3(2.0--8.5 )months and 7.9(4.0--14.7)months respectively in 9 dead patients and 7.7(1.3--21.0)months and 9.5(2.3--23.0)months in 13 alive patients. In all 22 patients, the survival rates in 6, 12 and 18 months were 78.9%, 47.5 % and 35.6 %, respectively. CONCLUSIONS: The results with combined metallic biliary stent placement and radiotherapy for the palliative treatment of malignant biliary obstruction in this study was more favorable, as compared with those of the other authors with only metallic biliary stent placement.
Brachytherapy ; Catheters ; Colon ; Common Bile Duct ; Gallbladder ; Head and Neck Neoplasms ; Humans ; Palliative Care ; Radiotherapy* ; Stents* ; Stomach ; Survival Rate

No abstract available.
Humans ; Infant, Newborn*

A 24-year Korean woman presented with bizarre pigmentary skin changes. Eruptive vellus hair cysts (EVHC) were observed in conjunction with Hypomelanosis of Ito (HI). Also, the karyotype of 45XO with typical clinical symptoms of Turner's syndrome was detected in this patient, which has been rarely reported in HI as a chromosomal defect. EVHC may manifest as a rare skin manifestation of Hl.
Female ; Hair* ; Humans ; Hypopigmentation* ; Karyotype ; Skin ; Skin Manifestations ; Turner Syndrome*

Urethral catheterization has become a more common clinical procedure. Many investigators claim that high incidence of infection is encountered in urethral catheterization, while others have underestimated the incidence. In this study an attempt has been made to clarify the degree, pathogens and frequency of urinary tract infection following a single catheterization in normal and uninfected bladder of 30 inpatients without urological symptoms. No antibiotics or sulfa-drugs were used prior to admission or during this study. Urine for quantitative culture was collected by aseptic catheterization and self-voided mid-stream urine obtained 24 and 48 hours following catheterization for colony count. If necessary, urine was also collected after 7 days. Colony count over 10.000 per ml. was defined as bacteriuria and over 100,000 per ml. as significant bacteriuria. The results of this study are summarized as follows: 1) Of 30 cases, bacteriuria was observed in 7 (23.3%). Escherichia coli in 3, Pseudomonas aeruginosa in 1. Staphylococcus+ Diphtheroids in 2 and Streptococcus fecalis in 1. This includes Escherichia coli over 100,000 per ml. and significant urinary symptoms. 2) A single aseptic catheterization might lead to bacteriuria and a focus of urinary tract infection.
Anti-Bacterial Agents ; Bacteriuria ; Catheterization* ; Catheters* ; Escherichia coli ; Humans ; Incidence ; Inpatients ; Pseudomonas aeruginosa ; Research Personnel ; Streptococcus ; Urinary Bladder* ; Urinary Catheterization ; Urinary Catheters ; Urinary Tract Infections* ; Urinary Tract*

PURPOSE: PVP using a high-power potassium-titanly-phosphate(KTP) laser offers safe and efficacious surgical therapy for men with symptomatic BPH. To demonstrate its efficacy, safety and durability, we present the results of PVP for treatment of BPH with 12 month follow-up. MATERIALS AND METHODS: 104 consecutive men with symptomatic BPH underwent PVP with an 80 W KTP laser (Laserscope) between July 2003 and August 2004. All underwent preoperative and postoperative evaluation, including assessments of international prostate symptom score(IPSS), quality of life(QOL), peak urinary flow rate(Qmax), post-void residual volume(PVR), prostate specific antigen(PSA), and ultrasound prostate volume(PV). Secondary outcome parameters included surgical time, anesthesia, and length of catheterization. Follow-up assessment occurred at 1, 3, 6, and 12 months. Data were analyzed using the Wilcoxon signed rank test. RESULTS: Preoperative mean PV was 57.2+/-4.2 ml. PV decreased to 38.9, 35.4, 32.8 and 35.8 at 1, 3, 6 and 12 months (p <0.01 versus preoperative value). Mean improvements in IPSS, QOL, Qmax, and PVR at 12 months were 67%, 81%, 138% and 94%, respectively(p <0.001). Mean operative time was 26.3+/-15.0 minutes. Anesthesia included pudendal and prostatic block(n=102) and spinal anesthesia(n=2). Ninety-nine(95%) patients were treated as outpatients( <12 hrs) and the remaining 5 patients were admitted for 1 or 2 hospital days. Mean catheterization times were 9.8+/-3.1 hours(range 0~72), with 28(27%) patients not requiring a catheter post-operatively. Minor complications included mild hematuria lasting 3 weeks(3.8%), transient post-operative retention(2.9%), urge incontinence(1.9%), transient dysuria(25%), frequency(21.2%), urgency(17.3%) and retrograde ejaculation(41%). CONCLUSIONS: These results demonstrate that PVP is safe and efficacious for the treatment of symptomatic BPH. Long follow-up will further validate this new modality as the standard for surgical treatment of BPH.
Anesthesia ; Catheterization ; Catheters ; Follow-Up Studies ; Hematuria ; Humans ; Lasers, Solid-State* ; Male ; Operative Time ; Prostate ; Ultrasonography ; Volatilization*

Mechanism and process of bladder regeneration were experimentally observed in this study, using 3S Korean mongrel dogs weighing 15~25kg. The animals were divided into two experimental groups. In the first group (A) of 27 dogs subtotal cystectomy and urinary diversion were underwent to study the influence of urine on the bladder regeneration and the second group (B) of 8 dogs in which only subtotal cystectomy was performed was investigated for the process of regeneration. In the group A the dogs were sacrificed every week in the first one month, every 2 weeks in the following 5 months and every 4 weeks thereafter. The bladder was examined morphologically and histologically and no remarkable regenerative process was observed. In the group B 8 dogs were sacrificed at intervals of 2 or 4 weeks after 6 months of initial operation. The distinct regenerated bladder was noticed and its completion took place in 36 weeks. The area of regeneration showed a definite thick walled pouch with normal uroepithelium and normal color. From these observations it is postulated that urine might have played a role in regeneration of the bladder. possibly by mechanical stimulation and a further study will be necessary to investigate a possible chemical factor.
Animals ; Cystectomy ; Dogs ; Regeneration* ; Urinary Bladder* ; Urinary Diversion

No abstract available.
Lichens*