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3.Detection of cytomegalovirus DNA by polymerase chain reaction in renal tissues from various glomerulonephritis.

Jae Hoon SONG ; Won Suk YANG ; Soon Bae KIM ; Bin YOO ; Yoo Kyum KIM ; Chang Ki HONG ; Jung Sik PARK

Korean Journal of Infectious Diseases 1993;25(2):151-157

4.Serum Insulin-like Growth Factors and their Binding Proteins in the Women With Polycystic Ovary.

Jae Sook ROH ; Jung Bae YOO ; Soo Hyun JO ; Hak Soon KIM ; Yoon Yeong HWANG

Korean Journal of Obstetrics and Gynecology 2000;43(5):795-805

OBJECTIVE: The involvement of IGF system in hyperandrogenism and abnormal follicular development is controversial. This study is to assess whether IGF system contribute to it in the women with polycystic ovary(PCO). METHODS: Baseline serum levels of luteinizing hormone (LH), follicle stimulating hormone (FSH), estradiol (E2), testosterone (T), androstenedione (ADD), prolactin, thyroid stimulating hormone (TSH), free insulin-like growth factor(IGF)-I, free IGF-II, insulin-like growth factor binding protein(IGFBP)-1, and IGFBP-3 were measured in twelve healthy regularly cycling volunteers and forty-two women with PCO then, the changes of baseline serum levels were evaluated after laparoscopic ovarian electrocauterization in nine PCO patients. In addition, the expression pattern of IGF-I and IGF-II was examined in the ovary of control and PCO group. RESULTS: Baseline levels of LH, ADD, free IGF-II, and IGFBP-3 were significantly higher in PCO group. However, there were no significant differences in the levels of free IGF-I and IGFBP-1, although free IGF-I showed decreasing tendency in PCO group. And there was a significant positive correlation between the LH and free IGF-II level in the PCO(P=0.011, r2=0.3899), but not in the control. After ovarian electrocauterization, LH, T, and ADD levels decreased, and free IGF-I and IGFBP-3 level increased. While free IGF-II and IGFBP-1 level showed no significant changes. In the ovary, expression of both IGFs showed similar pattern in normal and PCO ovaries. CONCLUSIONS: The elevated IGFBP-3 level may alter the bioavailability of IGF(s) in the PCO. The change in IGF-I level and resumption of ovulation after electrocauterization, suggest a possible role of IGF system in the impairment of follicular development in the PCO.
Androstenedione ; Biological Availability ; Carrier Proteins* ; Estradiol ; Female ; Follicle Stimulating Hormone ; Humans ; Hyperandrogenism ; Insulin-Like Growth Factor Binding Protein 1 ; Insulin-Like Growth Factor Binding Protein 3 ; Insulin-Like Growth Factor I ; Insulin-Like Growth Factor II ; Luteinizing Hormone ; Ovary* ; Ovulation ; Prolactin ; Somatomedins* ; Testosterone ; Thyrotropin ; Volunteers

5.A case of pregnancy complicated primary hypothyroidism presenting with cardiac tamonade resulted from massive pericardial effusion and megacolon.

Ki Heon LEE ; Jung Bae YOO ; Kyung Tai KIM ; Youn Yeoung HWANG ; Jai Auk LEE

Korean Journal of Perinatology 1993;4(3):433-440

1.Clinical application of tape-recorder and telemetry system for analysis of fetal heart rate.

2.Single Intrauterine Fetal Demise in Twin Gestation.

3.Detection of cytomegalovirus DNA by polymerase chain reaction in renal tissues from various glomerulonephritis.

4.Serum Insulin-like Growth Factors and their Binding Proteins in the Women With Polycystic Ovary.

5.A case of pregnancy complicated primary hypothyroidism presenting with cardiac tamonade resulted from massive pericardial effusion and megacolon.

6.Expression Pattern of Insulin - like Growth Factor - II in Human Fallopian Tubal Epithelium.

7.Invasive carcinoma after a simple hysterectomy for microinvasive carcinoma of uterine cervix: a case report.

8.Two Cases of Meckel Gruber Syndrome.

9.Two Cases of Acardiac Acephalus.

10.A quick measurement of stress in outpatient clinic setting.

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