A 36 year old infertile was diagnosed endometrial adenocarcinoma by endometrial biopy due to vaginal bleeding. She was characterized by obesity, hirsutism and infertility. Diagnosis was confirmed endometrial adenocarcinoma(Geade I) associated with polycystic ovarian disease postoperatively. We experienced this case and so report this case with a brief review of literatures.
Adenocarcinoma* ; Adult ; Diagnosis ; Female ; Hirsutism ; Humans ; Infertility ; Obesity ; Ovarian Diseases* ; Uterine Hemorrhage

A case of quadriplegia resulted from cervical penetrating wound was admitted to chosun university hospital intensive care unit, and undergone steroid therapy and antibiotics therapy. On the 6th hospital day, the septic complication was developed and it proved to be bacterial meningitis by CSF examination. Broad spectrum antibiotics was administered immediately after the diagnosis and the patient was monitored carefully. The bacterial meningitis was improved and no other serious complication was developed. The patient was discharged with permanent neurologic deficit, quadriplegia.
Anti-Bacterial Agents ; Diagnosis ; Humans ; Intensive Care Units ; Meningitis, Bacterial ; Neurologic Manifestations ; Quadriplegia* ; Wounds and Injuries* ; Wounds, Penetrating

PURPOSE: The purpose was to investigate the factors influencing alcohol consuming behavior of the female university students to provide the basic data for a nursing intervention program to improve health and prohibit of alcohol consuming behavior. METHOD: The subjects were 134 female university students, studying at K university and K educational university in Chungnam province from April 1 to 20, 2002. The instruments were the alcohol consuming behavior scale, that is drinking intensity score, and alcohol problem developed by Shin(1998), refusal self-efficacy scale by Aas et. al.(1995), alcohol expectancy by Goldman at. al.(1989), TPQ scale by Cloninger(1991), depression scale modified by Shin(1977) using Zung(1965)' tool, family cohesion scale by Olson at. al.(1983). The data were analyzed using descriptive statistics, Pearson correlation coefficient, canonical correlation and stepwise multiple regression. RESULT: The most powerful predictor of alcohol consuming behavior was influence of friends-drinking(21.0%). A combination of economic status(8.0%), and personality of novelty seeking(3.0%), accounted for 32.0% of the variance in alcohol consuming behavior. CONCLUSION: I recommended that economic status, influence of friends drinking frequently, and personality of novelty seeking were contained of the developing nursing intervention program for decreasing the alcohol consuming behavior in female university students.
Chungcheongnam-do ; Depression ; Disulfiram ; Drinking ; Female* ; Friends ; Humans ; Nursing ; Child Health

Post-traumatic stress disorder (PTSD) is a serious problem not only among workers who experience industrial accidents but also among workers who witness such accidents. Early intervention is needed to prevent prolonged psychological problems. There has been no study conducted regarding the psychological problems of and interventions for bystander workers in Korea. This study introduces the experience of intervention on psychological problems at the Busan Workers' Health Center workers who witnessed their colleagues' death. An investigation and an intervention were conducted according to the Korean Occupational Safety and Health Agency (KOSHA) Guide. In total, 21 individuals including indirect observers showed statistical differences on scores of the Impact Event Scale Revised and the Patient Health Questionnaire 9 after the intervention. Future interventions and research involving a larger sample size over a longer period are needed. The KOSHA Guide could be a useful tool for urgent psychological intervention in the event of major workplace disasters.
Accidents, Occupational* ; Busan ; Disasters ; Early Intervention (Education) ; Humans ; Korea ; Occupational Health ; Sample Size ; Stress Disorders, Post-Traumatic*

We report a case of successful normal vaginal delivery in a 28 years old female patient who received living related renal transplantation three years ago due to chronic renal failure resulted from eclampsia and polyhydroammnios.
Adult ; Eclampsia ; Female ; Humans ; Kidney Failure, Chronic ; Kidney Transplantation* ; Pregnancy ; Transplantation

OBJECTIVE: Our purpose was to investigate urinary malondialdehyde (MDA), manganese superoxide dismutase (Mn-SOD) activity and polymorphism in placental tissues of women with preeclampsia and to evaluate oxidative stress in the pathophysiology of preeclampsia. METHODS: Urins and placental tissues were obtained from 20 normal and 20 preeclamptic women at 3rd trimester. Urinary MDA was assayed by an high performanance liquid chromatography (HPLC). The placental Mn-SOD activity was assayed by westen blotting and The placental Mn-SOD genotyping was assayed by PCR-RFLP. Data were analyzed statistically using Student's t-test and Chi-square test. RESULTS: 1) Urinary concentration of MDA was not significantly different in preeclampsia (4.43+/-2.37 ug/g) as compared with normotensive pregnancy (4.39+/-1.17 ug/g). 2) Preeclamptic women had similar Mn-SOD activity in placenta (1.04+/-0.04U/mL protein) as compared with normotensive pregnancy (1.44+/-0.34 U/mL protein). 3) No significant difference in the polymorphismthe of Mn-SOD genotype in placenta was observed between preeclampsia and normotensive pregnancy (X2=0.06, p>0.05) CONCLUSION: The findings in this study do not show that oxidative stress might be a pathogenetically relevent process causally contributing to the disease, and polymorphism in the Mn-SOD genotype in placenta do not seem to be risk factors for preeclampsia.
Chromatography, Liquid ; Female ; Genotype ; Humans ; Malondialdehyde ; Oxidative Stress ; Placenta ; Polymorphism, Genetic* ; Pre-Eclampsia* ; Pregnancy* ; Risk Factors ; Superoxide Dismutase* ; Superoxides*

Mycophenolate mofetil (MMF) is an immunosuppressive agent used to treat severe lupus, including lupus nephritis. Common adverse effects of MMF include gastrointestinal and hematological manifestations; however, cardiac toxicity in association with MMF has not been reported. We present a 21-year-old woman with lupus nephritis who developed ventricular tachycardia 2 hours after an overdose of MMF (34 g). Ventricular bigeminy was documented 12 hours after the MMF overdose. Transthoracic echocardiography showed no evidence of structural heart disease. The ventricular arrhythmia was successfully treated with potassium replacement, hydration, and cholestyramine. This case suggests that an overdose of MMF can induce ventricular tachycardia, and electrocardiogram monitoring is critical to identify this rare cardiac complication of MMF.
Arrhythmias, Cardiac ; Cardiotoxicity ; Cholestyramine Resin ; Echocardiography ; Electrocardiography ; Female ; Heart Diseases ; Humans ; Lupus Erythematosus, Systemic ; Lupus Nephritis ; Mycophenolic Acid ; Potassium ; Tachycardia, Ventricular ; Young Adult

Mycophenolate mofetil (MMF) is an immunosuppressive agent used to treat severe lupus, including lupus nephritis. Common adverse effects of MMF include gastrointestinal and hematological manifestations; however, cardiac toxicity in association with MMF has not been reported. We present a 21-year-old woman with lupus nephritis who developed ventricular tachycardia 2 hours after an overdose of MMF (34 g). Ventricular bigeminy was documented 12 hours after the MMF overdose. Transthoracic echocardiography showed no evidence of structural heart disease. The ventricular arrhythmia was successfully treated with potassium replacement, hydration, and cholestyramine. This case suggests that an overdose of MMF can induce ventricular tachycardia, and electrocardiogram monitoring is critical to identify this rare cardiac complication of MMF.

BACKGROUND: To examine the effect of weight gain during pregnancy and prepregnancy body mass index on infant birth weight in normal term pregnancy. METHODS: We analyzed the weight data from 501 women who were in healthy singleton term pregnancy in a general hospital in Seoul from Jan. 2001 to Jun. 2001. Among the 501 women, 209 women whose data were available to calculate weight gain in every trimester were chosen. To study the effect of maternal weight gain on infant birth weight, multiple regression analysis, controlled for selected covariables, was carried out on the entire sample and on each prepregnancy weight group. RESULTS: In all the subjects both prepregnancy body mass and weight gain significantly influenced birth weight. For the lower and normal BMI, each kilogram of maternal weight gain significantly increased birth weight. CONCLUSION: These observations supports the recent evidence for the association between maternal weight gain and birth weight, but only for woman whose prepregnancy BMI are lower and normal. High maternal prepregnancy BMI did not have any influence of weight gain on birth weight.
Birth Weight* ; Body Mass Index* ; Female ; Hospitals, General ; Humans ; Infant* ; Parturition* ; Pregnancy* ; Seoul ; Weight Gain*

OBJECTIVE: To compare the diagnostic performance of digital breast tomosynthesis (DBT) and conventional breast ultrasound (US) to characterize breast lesions as benign or malignant. MATERIALS AND METHODS: A total of 332 women, presenting for screening examinations or for breast biopsy between March and June 2012 were recruited to undergo digital mammography (DM), DBT, and breast US examination. Among them, 113 patients with 119 breast lesions depicted on DM were finally included. Three blinded radiologists performed an enriched reader study and reviewed the DBT and US images. Each reader analyzed the lesions in random order, assigned Breast Imaging Reporting and Data System (BI-RADS) descriptors, rated the images for the likelihood of malignancy (%) and made a BI-RADS final assessment. Diagnostic accuracy, as assessed by the area under the receiver operating characteristic curve, sensitivity, and specificity of DBT and US were compared. RESULTS: Among the 119 breast lesions depicted on DM, 75 were malignant and the remaining 44 were benign. The average diagnostic performance for characterizing breast lesions as benign or malignant in terms of area under the curve was 0.899 for DBT and 0.914 for US (p = 0.394). Mean sensitivity (97.3% vs. 98.7%, p = 0.508) and specificity (44.7% vs. 39.4%, p = 0.360) were also not significantly different. CONCLUSION: Digital breast tomosynthesis may provide similar reader lesion characterization performance to that of US for breast lesions depicted on DM.
Adult ; Aged ; Biopsy ; Breast/*pathology ; Breast Neoplasms/*diagnosis/radiography/ultrasonography ; Female ; Humans ; Mammography/*methods ; Middle Aged ; ROC Curve ; Radiographic Image Enhancement/*methods ; Retrospective Studies ; Sensitivity and Specificity ; Ultrasonography, Mammary/*methods