This study was to find out whether there were differences in the levels of depressions between positive and negative schizophrenics. This research was derived from the fact that negative schizophrenics show higher levels of depression than positive schizophrenics. This study also examined the levels of psychomotor dysfunction in positive and negative schizophrenics. For this study, there were 453 subjects. They consisted of 119 positive schizophrenics, 122 negative schizophrenics and 212 normal people. They were asked to complete Zung's Self-Rating Depression Scale(SDS) and to perform one subtest, Digit Symbol of KWIS(Korean Wechsler Intelligence SCALE). Subjects levels of depression were measured by the SDS. The level of psychomotor dysfunction was measured by Digit Symbol subtest of Korean Wechsler Intelligence Scale. ANOVA and Duncan's multiple comparison analysis were used to examine whether there were differences of depression and psychomotor dysfunction among the normal people, positive and negative schizophrenics. The results were as follows ; It was found that the depression level was higher in the negative schizophrenic patients than positive schizophrenic patients. Levels of depression were significantly higher in negative schizophrenics than positive schizophrenics. Psychomotor retardation symptom was the most effective variable that discriminates between the normals and the schizophrenics. And it would be concluded that the psychomotor dysfunction was more severe in negative schizophrenics than positive schizophrenics.
Depression* ; Humans ; Intelligence

In order to clarify the contamination of vegetable gardens with human intestinal helminths, the soil samples were examined for the presence of eggs and larvae during the period from September 1973 to August l974. When soil samples collected from the vegetable gardens in Taegu were examined, four species of helminth eggs (ascarid, whipworm, hookworm and liver fluke) and a number of unknown eggs were found. Ascarid was found to be highest in the rate of detection(82.5 percent), followed by whipworm. The rates of hookworm, liver fuke and Trichostrongylus species were unexpectedly low. There was no difference between detection rate of vegetable gardens and that of vinyl green houses. However, the average number of helminth eggs detected from the soil of vinyl green houses was higher than the number of vegetable gardens. In the monthly incidence of ascarid eggs, the highest rate was found in September, and the least often was observed in August. While, the peak in the average number of the egg was encountered in August. There was no distinct trend in the monthly incidence of whipworm. However, it is likely that the detection number of whipworm per 100 gm of soil examined was relatively abundant in a period from May to August, and very little from October to April of next year. When the soil of vegetable gardens was divided into superficial, intermediate and deep layers and examined for presence of ascarid egg. The average number of the eggs found of the superficial layer was more abundant than those of the intermediate and deep layers, but the rate for the former was similar with the latter. In the demonstration of larval nematodes from the soil of vegetable gardens and vinyl houses, there found the filariform and rhabditoid larvae of hookworm and the larvae of Trichostrongylus species and unknown one. The majority of the larvae detected was belonged to unknown species, followed by hookworm larvae. The least was found in the rate of Trichostrongylus species. Generally, the filariform larva of hookwom could be detected during the hot season from May to August, but no larva was found in the winter. This suggests that the soil of vegetable gardens and vinyl green houses in Taegu is contaminated with human intestinal helminths.
parasitology-helminth-nematoda-trematoda ; Ascaris lumbricoides ; Trichuris trichiura ; hookworm ; Clonorchis sinensis ; egg ; larva

No abstract available.
Humans ; Korea*

No abstract available.
Complementary Therapies*

The purpose of this article was to determine the discriminant function analysis of the Korean Wechsler Intelligence Scale (KWIS) for 110 normal controls and 98 schizophrenics. Of special interest was to verify the clinical discriminant power of two subtests of the KWIS (Vocabulary and Digit Symbols) and Zung's Self-rating Anxiety Scale (SAS). Four major hypotheses were postulated. The normal control group would show higher scores then the schizophrenics; mean scores on both Vocabulary and Digit Symbol. The mean difference in Digit Symbol between the two groups would be greater than that in the Vocabulary. There would be no significant relation among Digit Symbol, Vocabulary, and Anxiety. The most powerful discriminant power would be expected from subtest of Digit Symbol. The mean discriminant scores were 1.34425 for the control subjects, 1.34425 for the schizophrenics. The correctly discriminated percentage was 89.1% for the control subjects, 90.8% for the schizophrenics. From the findings it was concluded that both Digit Symbol and Vocabulary scales had strong diagnostic value but the former was more powerful than the latter. However, the Anxiety scales had less diagnostic value.
Anxiety ; Humans ; Intelligence ; Vocabulary ; Weights and Measures

Cyclosporine A (CSA), a lipophilic cyclic undecapeptide, is not accumulated evently in all tissues and has a high affinity to several tissues such as lymphoid organs, liver, and kidneys. From this point of view, it is reasonable to assume that the amount of CSA uptake would be correlated with the extent of cell injury. On the other hand, verapamil, a Ca2+ channel blocker, bas been shown to ameliorate CSA nephrotoxicity. Since proximal tubule is the major site of drug transport and CSA uptake and its interaction with verapamil in isolated human renal proximal tubular cells. The CSA uptake rapidly increased over the first 5 min and then achieved almost steady-state after 10 min at all concentrations (0.5-10 uM). Kinetic analysis yielded that the Km and Vmax values of CSA were 5.6 uM and 86.2 p mol/mg cell protein/min, respectively. And Ca2+ depletion in media enhanced CSA uptake significantly but verapamil reduced it. These results suggest that the Ca2+ channels and CSA transporting sites on cell membrane are closely associated and that Ca2+ and CSA might be taken up competitively by proximal tubular cells.
Humans

Nephrotoxicity is the most common dose-limiting factor of cyclosporine A (CSA) in clinical usage. But the mechanism of CSA-induced nephrotoxicity still remains unresolved. Many authors insisted that CSA induced renal proximal tubular cell injury is due to the secondary effects following hemodynamic changes or endothelial cell damage, instead of direct toxicity by CSA. To find out that CSA has a direct toxicity to the proximal tubular cells, the author used primary cultures of human proximal tubular cells to eliminate the hemodynamic or endothelial influences that could be produced in in vivo model. In the present study, the viability against CSA was tested by the neutral red assay method with modulation of Ca2+ amount in incubating media and observed electron microscopically. The viability test showed direct toxic effect of CSA on human proximal tubular cells and this was enhanced by Ca2+ depletion in incubating media. Morphologically noted are accumulation of lipid droplets and polyribosomal dispersion, which may be association with inhibition of cellular synthetic activity. These results suggest the toxixity is a direct effect of cyclosporine and that toxic mechanism may be due to inhibition of cellular synthetic activity. And this experiment also showed that primary cultures of human renal proximal tubular cells can be a good in in vivo model for investigating CSA nephrotoxicity.
Humans

BACKGROUND: Chronically disabled rehabilitating patients influence their family members by their physical dysfunction. The purpose of this study was to know the relation of family function and physical function in disable person who is periodically treated in r ehabilitation department. METHODS: To know the family function according to physical disability, 64 patients(M/ F: 40/24) in rehabilitation clinic in 1 university hospital was studied by questionnaires including ADL(activity of daily living), IADL(instrumental actvity of daily living), FIM(functional independence measure), family APGAR. RESULTS: Causes of disabilities were stroke 2, traumatic brain injury 14, fracture 16, spinal cord injury 12, burn 2, arthritis 9, back pain syndrome 9 in order. Physical function of functional families was better than dysfunctional families. And physical function according to FIM score was statistically significant(p<0.05). Physical function was significantly(P value, ADL: 0.021, IADL: 0.009, FIM: 0.005) correlated with family APGAR score. CONCLUSIONS: Physical function and family function in rehabilitating patients with irreversible disability have significant correlations. Physician have to consider family function and dynamics in care of physically disabled patients.
Activities of Daily Living ; Apgar Score ; Arthritis ; Back Pain ; Brain Injuries ; Burns ; Disabled Persons ; Humans ; Rehabilitation ; Spinal Cord Injuries ; Stroke ; Surveys and Questionnaires

With aging, several progressive changes occur on the midface including descent of attenuated lower eyelid skin which creates a skeleton-like appearance with infraorbital hollowness, and descent of the malar fat pad with exaggeration of the nasolabial fold. Most of the procedures for midfacial rejuvenation require extensive peripheral-to-central dissection in the subcutaneous, sub-SMAS or subperiosteal plane. The author's procedure entails direct access to the midface through a subciliary incision, elevation of the orbicularis oculi muscle and ptotic malar soft tissue. It has been performed through subcutaneous dissection on 67 patient and subperiosteal dissection on 4 patients. Subcutaneous dissection on the midface was made laterally to the zygomaticus maior, medially to the levator labii superioris under the oricularis muscle and inferiorly beyond the nasolabial fold. The range of subperiosteal dissection was similar to subcutaneous dissection, except on the dissection plane. Suspension sutures made at the malar retaining ligament and infero-lateral portion of the orbicularis oculi were fixed to periosteum of the lateral canthal area. In some patients, this procedure was combined with forehead lift(4), temporal lift(2), upper blepharoplasty(28), cervicoplasty(2), and lateral canthoplasty(12). In 23 patients who had a particularly prominent tear trough, a fat sliding technique was combined. The author has followed up 62 patients from a minimum 2 months to a maximum 27 months. Complications included urdercorrection(3), longstanding malar fullness(2), ectropion(1), transient numbness(2), and cheek dimpling(1). In conclusion, this centrofacial can be applied to patients who have limited ptosis of the midface with mild nasolabial fold.
Adipose Tissue ; Aging ; Cheek ; Eyelids ; Forehead ; Humans ; Ligaments ; Nasolabial Fold ; Periosteum ; Rejuvenation ; Skin ; Sutures

No abstract available.
Headache*