2.Method of tumor volume evaluation using magnetic resonance imaging for outcome prediction in cervical cancer treated with concurrent chemotherapy and radiotherapy.
Radiation Oncology Journal 2012;30(2):70-77
PURPOSE: To evaluate the patterns of tumor shape and to compare tumor volume derived from simple diameter-based ellipsoid measurement with that derived from tracing the entire tumor contour using region of interest (ROI)-based 3D volumetry with respect to the prediction outcome in cervical cancer patients treated with concurrent chemotherapy and radiotherapy. MATERIALS AND METHODS: Magnetic resonance imaging was performed in 98 patients with cervical cancer (stage IB-IIIB). The tumor shape was classified into two categories: ellipsoid and non-ellipsoid shape. ROI-based volumetry was derived from each magnetic resonance slice on the work station. For the diameter-based surrogate "ellipsoid volume," the three orthogonal diameters were measured to calculate volume as an ellipsoid. RESULTS: The more than half of tumor (55.1%) had a non-ellipsoid configuration. The predictions for outcome were consistent between two volume groups, with overall survival of 93.6% and 87.7% for small tumor (<20 mL), 62.9% and 69.1% for intermediate-size tumor (20-39 mL), and 14.5% and 16.7% for large tumors (> or =40 mL) using ROI and diameter based measurement, respectively. Disease-free survival was 93.8% and 90.6% for small tumor, 54.3% and 62.7% for intermediate-size tumor, and 13.7% and 10.3% for large tumor using ROI and diameter based method, respectively. Differences in outcome between size groups were statistically significant, and the differences in outcome predicted by the tumor volume by two different methods. CONCLUSION: Our data suggested that large numbers of cervical cancers are not ellipsoid. However, simple diameter-based tumor volume measurement appears to be useful in comparison with ROI-based volumetry for predicting outcome in cervical cancer patients.
Disease-Free Survival
;
Humans
;
Magnetic Resonance Imaging
;
Magnetic Resonance Spectroscopy
;
Magnetics
;
Magnets
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Tumor Burden
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Uterine Cervical Neoplasms
3.A New Year's Greeting Message.
Journal of the Korean Medical Association 2005;48(1):2-2
No abstract available.
4.Genetics in Epilepsy.
Journal of the Korean Child Neurology Society 1999;6(2):205-214
5.A New Year's Greeting Message.
Journal of the Korean Medical Association 2004;47(1):3-3
No abstract available.
6.Situation of the Korean Medical Association about Animal Clone.
Journal of the Korean Medical Association 1999;42(9):826-829
No abstract available.
Animals*
;
Clone Cells*
7.Immune responses of mucosal epithelial cells in response to pathogenic microbial infections.
Journal of Asthma, Allergy and Clinical Immunology 2000;20(1):68-74
No abstract available.
Epithelial Cells*
8.Diagnosis and treatment of edema.
Korean Journal of Medicine 2005;69(5):574-577
No abstract available.
Diagnosis*
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Diuretics
;
Edema*
10.Psychiatric education in U.S. Medical Schools.
Journal of Korean Neuropsychiatric Association 1993;32(5):611-620
No abstract available.
Education*
;
Schools, Medical*
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