1.Enhancement of implementation management of developed programs and upgrading level of hospital scientific research management
Chinese Journal of Medical Science Research Management 2008;21(2):88-90
Not only shofld the process of program establishment be emphasized for the management of the newly developed programs,but also great attention should be paid to the normal management after the establishment.The management and supervision should be practiced on the whole process of the programs newly developed by hospital departments so that the written report on the program advancement should be submitted in the half a year as planned.Furthermdre,an exclusive account should be opened for the granted fund of the program;and the establishment of new research program and the purchase of equipment should be approved according to the related rules and regulations of the hospital.
2.Empirical Investigation and Countermeasure Analysis of the Present Situation of Medical Students′Medical Ethics Education
Huifang SHI ; Junfeng LIANG ; Junlan LI
Chinese Medical Ethics 2016;29(5):798-800
Objective:To investigate the present situation of medical students′medical ethics education and fur-ther to put forward countermeasures for medical colleges and universities. Method:With the methods of question-naire, literature and interview, medical students of the second grade and above in Xi′an Jiaotong University, Xin-jiang University and Xinjiang Medical University were investigated. SPSS 20. 0 was used to establish a database and frequency analysis method was used to analyze data. Results:It is suggested that some medical students′ motiva-tion to be a doctor is pure and the professional ethical identity is correct. There exist problems in the evaluation of ethics anomie behaviors. The students lack of cognition of medical ethics but pay more attention to medical technol-ogy. Most of the medical students think that clinical practice education and the model demonstration of teachers are conducive to medical ethics education. Conclusion: Universities can develop their own medical ethics education mode through various forms of classroom education, the involvement of old professors in teaching, strengthening learning of medical laws, daily ideological education by counselors and the construction of campus spiritual civiliza-tion.
3.Current progress in 3D printing for cardiovascular tissue engineering
Yao WANG ; Junfeng YANG ; Hongcan SHI
Chinese Journal of Thoracic and Cardiovascular Surgery 2016;32(7):444-446
In recent years, scientists paid close attention to the studies of 3D printing in cardiovascular tissue engineer-ing, which has made some advances.But how to promote cardiovascular tissue engineering for clinical application still needs deeper research.Here we discussed from three cardiovascular tissues ( myocardial tissue, heart valves, coronary) , which at-tempted to retrospect the current progress of 3 D printing in cardiovascular tissue engineering and provided a guidance of further investigations.
4.Endoscopic thyroidectomy with bipolar electrocoagulation
Chunlei SUN ; Pingkang CHEN ; Junfeng SHI
Chinese Journal of Minimally Invasive Surgery 2001;0(01):-
Objective To study the feasibility of endoscopic thyroidectomy with bipolar electrocoagulation. Methods Endoscopic partial thyroidectomy via precordial approach, mainly by using bipolar electrocoagulation and scissors, was accomplished in 21 patients with thyroid tumors with a diameter of 0.7~5.5 cm. Results The operation was accomplished endoscopically in 20 patients, whereas a conversion to open thyroidectomy was conducted in 1 patient. The mean incision length was 22 mm, the operation time was 69?47 min, and the blood loss was 55?41 ml. Postoperative analgesic treatment was required in 2 patients and no serious complications happened. Conclusions Endoscopic thyroidectomy with bipolar electrocoagulation is feasible in the absence of ultrasonic scalpel.
5.Hand-assisted laparoscopic colorectal resection: An analysis of 21 cases
Pingkang CHEN ; Chunlei SUN ; Junfeng SHI
Chinese Journal of Minimally Invasive Surgery 2005;0(11):-
Objective To evaluate the feasibility of hand-assisted laparoscopic colorectal resection. Methods Clinical data of 21 cases of hand-assisted laparoscopic colorectal resection in this hospital from October 2003 to August 2004 were retrospectively reviewed. Results The hand-assisted laparoscopic resection was accomplished in 20 cases. The mean operation time was 144 min, the mean blood loss was 120 ml, the mean number of dissected lymph nodes was 8.5, and the mean time to intestinal function recovery, 69 h. Postoperative abdominal bleeding was found in 1 case, which was cured with conservative therapy. A conversion to open surgery was needed in 1 case. Conclusions Hand-assisted laparoscopic colorectal resection safe, feasible, and radical, with advantages of fewer complications and simplicity of performance.
6.Evaluation of performance of Sysmex XT-2000i blood-counter system for the test of reticulocytes
Junfeng QIU ; Yuehong YE ; Jiang SHI
International Journal of Laboratory Medicine 2006;0(04):-
0.05.Conclusion Using XT-2000i Automated Hematology Analyzer to test the reticulocyte the reproducibility is better,and the linearity can content well with clinic,the rate of carry contamination is low,the stability is better too.Compared XT-2000i with the manual methods,the relativity is better. It can replace the manual methods.
7.Review of nanotechnology on 3D tissue engineering scaffolds
Junfeng YANG ; Yao WANG ; Hongcan SHI
International Journal of Surgery 2015;42(8):558-562
Nanoscale biomaterials,due to their excellent mechanical,chemical and biological properties,are now being applied in regenerative medicine.Nanoscale materials incorporation into 3D synthetic organ scaffolds has had a breakthrough in tissue engineering.This review provides an update report on the use of nanomaterials in 3D scaffolds of tissue engineering,including fabrication methods of 3D scaffolds of nanomaterials and their physicochemical properties,biocompatibility and degradability.
8.Current progess and prospects of tissue-engineered trachea research
Yao WANG ; Junfeng YANG ; Hongcan SHI
International Journal of Surgery 2015;42(10):717-720
In recent years,Scientists paid close attention to the studies and applications of tissue-engineered trachea,which have made some advances.But how to promote tissue-engineered trachea for clinical application still needs deeper research.Here we discussed from three key aspects of tissue-engineered trachea (Scaffold,Cell,Bioreactor),which attempted to retrospect the current progress in tissue-engineered trachea and provided a guidance of further investigations.
9.Effect of xingnao kaiqiao acupuncture method on stroke of different syndrome types
Lin GUO ; Xuemin SHI ; Junfeng XU
Chinese Journal of Tissue Engineering Research 2006;10(31):157-159
BACKGROUND: Xingnao kaiqiao acupuncture is a series of systematic acupuncture methods with yin channels in domination, assisted by specified standards of quantity manipulation, which was founded according to the pathogenesis of stroke, and it is effective in treating stroke.OBJECTIVE: To observe the effects of xingnao kaiqiao acupuncture on blood lipids and blood viscosity in stroke patients of different syndrome types.DESIGN: A comparative observation.SETTINGS: Institute of Acupuncture and Moxibustion, and Special Care Ward of Acupuncture, the First Affiliated Hospital of Tianjin College of Traditional Chinese Medicine.PARTICIPANTS: Totally 750 stroke inpatients (466 males and 284 females) were selected from the Special Care Ward of Acupuncture, the First Affiliated Hospital of Tianjin College of Traditional Chinese Medicine between January and December in 2001, the average age was (64±12) years,the disease course ranged from 2 hours to 3 years. All the patients were informed and agree with the therapeutic program.METHODS: ① The traditional Chinese medicine (TCM) syndrome differentiations of stroke were in reference to the fifth edition of Traditional Chinese Medicine and Internal Medicine. There were 688 cases of stroke of meridian and collateral type and 47 cases of stroke attacking zang-fu organs type. ② Huatuo filiform needles produced by Suzhou [1.0-1.5 cun in length, 0.32-0.38 mm in diameter (No. 30-28)] were used in the xingnao kaiqiao acupuncture. Firstly, the acupoints of bilateral Neiguan were acupunctured perpendicularly for about 0.5-1.0 cun, the reducing manipulation by twirling as well as lifting and thrusting the needle was performed for 1 minute; Secondly, the needle was inserted at Renzhong towards nasal septum for about 0.3-0.5 cun, the manipulation of heavy bird-peck needling was used till the eyeballs were wet or tears fell down; Then Sanyinjiao was acupunctured, the needle was inserted along the medial border of tibia at an angle of 45° with skin for about 1.0-1.5 cun, the reinforcing manipulation by lifting and thrusting the needle was performed till the ipsilateral lower limb had three tics; The acupoint of Weizhong was selected by lying and lifting the leg, the needle was inserted perpendicularly for 0.5-1.0 cun, and the reducing manipulation by lifting and thrusting was applied till the ipsilateral lower limb had three tics; The acupoint of Jiquan was acupunctured at 1 cun below the source point along the channel in avoidance of axillary hairs, the needle was inserted perpendicularly for 1.0-1.5 cun, and the reducing manipulation by lifting and thrusting was applied till the ipsilateral upper limb had three tics; The elbow was flexed to 120° for acupuncture at Chize, the needle was inserted perpendicularly for 1.0 cun, the reducing manipulation by lifting and thrusting was applied till the ipsilateral upper limb had three tics. Twice a day for 7 days as a course. ③ After four courses averagely, the whole blood viscosities were detected with the hemorrheologic detector, and the normal ranges for lowshear, middle-shear and high-shear of whole blood viscosities were 6.50-9.25, 4.35-5.45 and 3.65-4.40 mpa ·s respectively. The levels of total cholesterol and triglyceride were detected with blood lipid detector, and the normal ranges were 3.38-6.5 mmol/L and 0.56-0.147 mmol/L.MAIN OUTCOME MEASURES: The effects of xingnao kaiqiao acupuncture on the blood lipids and blood viscosity in stroke patients of different syndrome types were observed.RESULTS: Totally 690 and 721 cases finished the detections of whole blood viscosities and blood lipids respectively. There were obviously fewer cases with normal whole blood viscosities in the patients with stroke of meridian and collateral than in those with stroke attacking zang-fu organs (10.3%, 15.4%, P < 0.01), but markedly more cases with higher total cholesterol and triglyceride than in those with stroke attacking zang-fu organs (80.5%, 91.5%; 64.1%, 71.3%; P < 0.01).CONCLUSION: The levels of blood lipids in the patients with stroke of meridian and collateral are more abnormal than in those with stroke attacking zang-fu organs, but their blood viscosities are better than in those with stroke attacking zang-fu organs.
10.Study of the efficacy and toxicity of gemcitabine combined with nedaplatin in anthracycline and/or taxane -pretreated patients with metastatic triple -negative breast cancer
Xiaoyu SHI ; Jing ZHANG ; Wei MENG ; Likun SUN ; Junfeng ZHAO
Chinese Journal of Primary Medicine and Pharmacy 2016;23(5):712-715
Objective To evaluate the short -term efficacy and adverse reactions of gemcitabin combined with nedaplatin to patients with metastatic triple -negative breast cancer after taxane and/or anthracycline treatment. Methods Thirty -three patients with anthracycline and/or taxane -resistant metastatic triple -negative breast cancer received gemcitabin and nedaplatin regimen:gemcitabin 1 000 mg/m2,d1,8 days,intravenous;nedaplatin 80mg/m2,d1,intravenous.Treatments were repeated every 21 days and response rate was evaluated every two cycles. Results Of 33 patients, complete remission ( CR) in 1 case ( 3.03%), partial remission ( PR) in 13 cases (39.39%),stable disease(SD) in 11 cases(33.33%),progressive disease(PD) in 8 cases(24.24%),objective response rate was 42.42%.The main adverse reaction was bone marrow suppression and gastrointestinal reaction. Conclusion Combination therapy of gemcitabin and nedaplatin is an effective and well tolerated rescue regimen in anthracycline and/or taxane -resistant metastatic triple -negative breast cancer patients.