STUDY DESIGN: The treatment of a stable fracture around thoracolumbarjunction is a controversial subject. OBJECTIVES: To evaluate the result from long term follow-up of the stable spinal fracture around thoracolumbar junction according to the operation, osteoporosis and in situ extension bar, respectively. SUMMARY OF BACKGROUND DATA: The thoracolumbar junction is a transitional zone in which the kyphotic angle of thoracic spine is continued to the lordotic angle of lumbar splne. So it is prone to be injured biomechanically, and the stability of the spine around thoracolumbar junction is not determined yet. METHODS: We studied retrospectively 105 cases of the stable fracture around thoracolumbar junction from January 1985 to December 1995. The criteria of the stability were a compression fracture by Denis F., a bursting fracture without involvement of posterior column, a neural enchroachment of bony fragment below 30%, fracture without subluxation or dislocation in spinal junction. RESULTS: The most common cause was traffic accident and, the first lumbar vertebrate was common site. Below 30% of initial compression, the progression was not exceded 5% in operative group. But in nonoperative group, anterior compression was more progressed than initial compression over 5%. The degree of anterior compression was affected by osteoporosis and in situ extension bar just after injury. CONCLUSIONS: We suggest an anterior compression abode 30% in spinal body of thoracolumbar junction for an additional operative indication. The prognosis may be affected by osteoporosis and in situ extension bar.
Accidents, Traffic ; Dislocations ; Follow-Up Studies* ; Fractures, Compression ; Osteoporosis ; Prognosis ; Retrospective Studies ; Spinal Fractures ; Spine ; Vertebrates

No abstract available.

PURPOSE: This study aimed to find out any different characteristics in various different voiding symptom questionnaires in the outpatient clinics between interstitial cystitis and overactive bladder. MATERIALS AND METHODS: Between October 2005 and December 2007, retrospectively were analyzed the consecutive 41 IC female patients' and 43 OAB female patients' questionnaires, who had completed three questionnaires at the outpatient department (Incontinence Quality of Life; I-QoL, King's Health Questionnaire; KHQ, International Prostate Symptom Score; IPSS). Additionally, the 41 IC patients also completed O'Leary Sant Questionnaire (OLS, or ICSI/ICPI). RESULTS: No statistical differences existed in age and symptom duration between two groups (p>0.05). In I-QoL, only the social embarrassment score was statistically different between two groups (p<0.05), but the total score, avoidance and limiting behavior, and psychosocial impact scores were not (p>0.05). In KHQ, the general health perceptions, impact on life, social limitations, personal relationships, emotions, and sleep/energy scores were statistically different (p<0.033), but the role limitations, physical limitations, and incontinence severity measures scores were not (p>0.059). In IPSS, the straining symptom, and quality of life scores were different between two groups (p<0.05). The IC patients also completed OLS questionnaire with mean interstital cystitis symptom index score of 14.10+/-3.92, and interstitial cystitis problem index score of 11.79+/-3.75. CONCLUSIONS: This study showed that some differences among symptom questions in questionnaires did exist between the two groups and that the IC group had much more impaired quality of life than the OABs.
Ambulatory Care Facilities ; Cystitis ; Cystitis, Interstitial ; Female ; Humans ; Outpatients ; Prostate ; Quality of Life ; Retrospective Studies ; Sprains and Strains ; Urinary Bladder, Overactive

No abstract available.
Animals ; Histamine* ; Hydroxyzine* ; Rats* ; Urinary Bladder*

Lower urinary tract symptoms are highly prevalent and closely related to patients’ quality of life. Clinical research on urologic disease is essential for accumulating evidence on patient management; however, the major obstacle is converting patients’ subjective symptoms to objective parameters. The optimal application of well-developed and validated questionnaires is vital in achieving objectivity and minimizing bias in clinical research. Numerous questionnaires for measuring symptoms and quality of life in urologic diseases have been developed worldwide; however, they cannot be directly used in clinical studies without validation processes. This review aimed to explain the common procedures for translation, linguistic, and psychometric validation of developed questionnaires from other languages. Furthermore, we comprehensively reviewed currently available questionnaires for evaluating lower urinary tract symptoms in the Korean population.

No abstract available.
Myopathy, Central Core*

No abstract available.
Catheters*

No abstract available.
Posterior Leukoencephalopathy Syndrome ; Visual Fields

PURPOSE: Recently, rabbit vagina has been used as an experimental model to elucidate the pathophysiology of female sexual dysfuntion. However, there is few information on the regional differences on the contraction and relaxation mechanisms of the vaginal smooth muscle in the rabbit. MATERIALS AND METHODS: Histological and in vitro strip studies were performed using vaginal walls from 10-week-old New Zealand White rabbits discriminately according to the region (upper, middle or lower) and muscle orientation(longitudinal or circular). The contraction and relaxation responses of the vaginal smooth muscle to various neuromodulators and intrinsic intramural nerve stimulation were assessed. RESULTS: Upper and middle thirds of vagina were histologically characterized by abundant smooth muscle content. while lower third portion was composed of numerous sinusoids scattered among smooth muscle bundles. The peak amplitude of high KCl (60 mM)-induced contraction per tissue strip weight was regionally different (upper >mid > lower). Strong concentration-dependent contractile responses to adrenergic agents(epinephrine, norepinephrine, phenylephrine and isopreterenol) were observed. Contractile responses induced by adrenergic agonists showed regional difference: mainly tonic nature in lower part and strong phasic in middle and upper vagina. Lower third portion was characterized by its prominent relaxation response, which was inhibited by N-omega-nitro-L-arginine methyl ester (NAME, 63.3+/-3.2%) and D-vasoactive intestinal peptide(VIP) (5.6+/-3.4%), a VIP antagonist. The presence of D-VIP amplified the NAME-induced inhibitory effect on the nerve-mediated relaxation(97.1+/-2.1%). The muscle orientation did not affect the results. CONCLUSIONS: Although the contractile response was identified in all regions, relaxation was prominent in the lower third portion of rabbit vagina, Therefore, the use of lower third portion would be recommended for further study on the relaxation response of rabbit vagina. The contractile function of vagina awaits future investigation.
Adrenergic Agonists ; Female ; Humans ; Models, Theoretical ; Muscle, Smooth ; Neurotransmitter Agents ; Nitric Oxide ; Norepinephrine ; Phenylephrine ; Rabbits* ; Relaxation ; Vagina*

Purpose: To evaluate the efficacy and safety of holmium laser enucleation of the prostate (HoLEP) in a large prospective cohort of patients with benign prostatic hyperplasia (BPH) through systematic follow-up at a single institution. Materials and Methods: Clinical outcomes were analyzed between August 2008 and June 2022. Patients were followed-up at 2 weeks, 3 months and 6 months postoperatively. Results: A total of 3,000 patients (mean age, 69.6±7.7 years) underwent HoLEP. Baseline total International Prostate Symptom Score (IPSS) was 19.3±7.7 and maximum flow rate (Qmax) was 9.4±4.8 mL/s. Mean total prostate volume was 67.7±3.4 mL. Total operation time was 60.7±31.5 minutes, and catheterization time was 1.0 days (range, 1.0–1.0 days). At 6 months postoperatively, the total IPSS decreased to 6.6±5.8 and Qmax increased to 22.2±11.3 mL/s. Complications at 6 months postoperatively included stress urinary incontinence (SUI) in 36 patients (1.9%), urgency urinary incontinence (UUI) in 25 (1.3%), bladder neck contracture (BNC) requiring transurethral incision (TUI) in 16 (0.5%), and urethral stricture in 29 (1.0%). Eleven patients (0.4%) with prostatic fossa stones required stone removal. Sixty-one patients (2.0%) required secondary surgery (transurethral coagulation, 16 [0.5%];TUI for BNC, 16 [0.5%]; stone removal for prostatic fossa stones, 11 [0.4%]; and endoscopic internal urethrotomy for urethral stricture, 18 [0.6%]). Conclusions Mid-term follow-up results after HoLEP in BPH patients showed excellent efficacy and low complication rates. Unlike previous reports, the incidence of SUI and UUI after HoLEP was low, but the occurrence of de novo stone formation in prostatic fossa was notable.