PURPOSE: Platelet Rich Plasma(PRP) application is increasing with sinus inlay bone graft, but there is few research with radiographic ananlysis on effect of PRP in maxillary sinus. The author investigated the amount of bony changes of maxillary sinus for dental implantation among the patients with maxillary inlay graft. MATERIALS AND METHODS: With 10 patients who were treated with sinus inlay autologous bone grafting combined with PRP technique, and with 5 patients who were treated with sinus inlay grafting only without PRP, the panoramic radiographys which were taken at preoperation, immediate postoperation, 3months postoperation, and 4 months postoperation(a month after dental implantation)periods were analysed. The films had been scanned, and then proceeded throughout image analysis system. The bone density of maxillary grafted sites was compared with adjacent tooth enamel density and remeasured according to density luminosity of each film. The density changes on PRP group and bone graft only group were an lysed with non-parameteric statistics method. RESULTS: In PRP combined patients group, bone density on postoperation periods was increased totally. The remarkable enhanced change of bone density was observed on 3 months postoperation period, thereafter the increasing rate was slightly reduced . In only bone graft patients group, bone density on postoperation periods was also increased compared with preoperation period, but the bone density of 4 months postoperation period was decreased compared with 3 months postoperation period. The amount of bone density on PRP group was significantly changed according to periods in contrast to bone graft only group. CONCLUSION: The bone density on PRP group was remarkably increased at 3 months postoperation compared to bone graft only group and it was seemed to be associated with more new bone formation, less grafted bone resorption at bone grafted sites with PRP.
Blood Platelets* ; Bone Density ; Bone Resorption ; Bone Transplantation ; Dental Enamel ; Dental Implantation ; Dental Implants ; Humans ; Inlays ; Maxillary Sinus ; Osteogenesis ; Platelet-Rich Plasma ; Tooth ; Transplants

Polyarteritis nodosa is a systemic inflammatory disease resulting from necrotizing angitis of small to medium sized arteries. It involves various organs, including the gastrointestinal tract, which is involved in about 50% of all cases. Numerous complications-including abdominal pain, vomiting, and hematemesis-have been reported, but the CT findings have not been described. We report the CT findings in a case of gastric polyarteritis nodosa, and correlate these with the histopathologic findings.
Abdominal Pain ; Arteries ; Arteritis ; Gastrointestinal Tract ; Polyarteritis Nodosa* ; Stomach* ; Vomiting

Primary papillary serous carcinoma of the peritoneum is a rare primary tumor involving the peritoneum. Histologically, it is indistinguishable from serous ovarian papillary carcinoma, although it either spares the o-varies or only microscopically involves their surface. The characteristic features of this tumor are extensive peritoneal and omental masses or implants with psammomatous calcification, and ascites. In addition, it can occur focally in the pelvic peritoneum. We report the CT findings, with histopathologic correlation of primary papillary serous carcinoma of the peritoneum occurring in the upper mesorectum.
Ascites ; Carcinoma, Papillary ; Peritoneum*

This study aimed to develop and evaluate health educational information system on internet to train health center workers. Internet-based Public Health Manpower Training Program was developed based on the findings of the needs of health center worker. It consisted of E-mail based on-line lesson. The effects of developed Internet-based Public Health Manpower Training Program were assessed by questionnaires of users about legibility, readability, satisfaction, changes in level of knowledge, and practical uses, etc. Most users(94.3%) of Internet-based Public Health Manpower Training Program reported that they were satisfied with the programs, and 90% of users reported that the programs improved their performance in health education, consultation and medical examination. Knowledge levels of users were elevated after program participation(statistically non significant). Internet-based Public Health Manpower Training Program had positive effects on the performance of health center workers, and we expect this program to help the planning for public health manpower.
Community Health Centers ; Comprehension ; Education* ; Electronic Mail ; Health Education ; Information Systems ; Internet ; Public Health* ; Surveys and Questionnaires

BACKGROUND: Laser therapy is generally postponed until scar maturation. We speculated that the use of laser therapy at the beginning of the wound healing process might minimize discomfort and problems at an early stage. METHODS: From January 2013 to May 2014, we conducted a study of 50 patients who underwent primary closure or scar revision procedures due to facial scarring. Within 1 to 2 weeks after the removal of all stitches, we performed laser treatments with a 532-nm neodymium-doped yttrium aluminium garnet (Nd:YAG) laser. To assess the improvement of the scars, we evaluated the scars using the Vancouver Scar Scale (VSS) and conducted a photo analysis using a computer graphics program. RESULTS: The mean score on the VSS decreased from 5.99 to 1.49 after the laser treatment. The score for each evaluation item decreased, meaning that the scars improved. The differences showed statistical significance. In the photo analysis that was conducted using Adobe Photoshop, the mean brightness of the pixels located within the scar territory increased from 61.54% to 69.42% after laser treatment, and the mean chroma decreased from 50.65% to 43.12%. These changes were statistically significant. CONCLUSIONS: We used a 532-nm Nd:YAG laser at an early stage of scar formation and confirmed improvements in the redness, hyperpigmentation, and hypertrophy of the scars shortly after treatment.
Cicatrix* ; Computer Graphics ; Humans ; Hyperpigmentation ; Hypertrophy ; Laser Therapy ; Wound Healing ; Yttrium

BACKGROUND: Laser therapy is generally postponed until scar maturation. We speculated that the use of laser therapy at the beginning of the wound healing process might minimize discomfort and problems at an early stage. METHODS: From January 2013 to May 2014, we conducted a study of 50 patients who underwent primary closure or scar revision procedures due to facial scarring. Within 1 to 2 weeks after the removal of all stitches, we performed laser treatments with a 532-nm neodymium-doped yttrium aluminium garnet (Nd:YAG) laser. To assess the improvement of the scars, we evaluated the scars using the Vancouver Scar Scale (VSS) and conducted a photo analysis using a computer graphics program. RESULTS: The mean score on the VSS decreased from 5.99 to 1.49 after the laser treatment. The score for each evaluation item decreased, meaning that the scars improved. The differences showed statistical significance. In the photo analysis that was conducted using Adobe Photoshop, the mean brightness of the pixels located within the scar territory increased from 61.54% to 69.42% after laser treatment, and the mean chroma decreased from 50.65% to 43.12%. These changes were statistically significant. CONCLUSIONS: We used a 532-nm Nd:YAG laser at an early stage of scar formation and confirmed improvements in the redness, hyperpigmentation, and hypertrophy of the scars shortly after treatment.
Cicatrix* ; Computer Graphics ; Humans ; Hyperpigmentation ; Hypertrophy ; Laser Therapy ; Wound Healing ; Yttrium

Interrupted aortic arch may be defined as a discontinuity of the aortic arch. This uncommon anomaly was first described by Steidele in 1778 and was later classified into 3 types by Celoria and Patton. We experienced the case of a 25-year-old male with an interrupted aortic arch(Type B) which was well supplied by collateral circulations. Ligation of collateral supplies and a Y-graft replacement from ascending aorta to descending thoracic aorta and left subclavian artery was done. Postoperative aortogram revealed no collateral circulations and good continuity of the aorta without narrowing of the anatomic site. During the period of 2-month follow up, the patient was able to lead a relatively active life.
Adult ; Aorta ; Aorta, Thoracic ; Collateral Circulation ; Equipment and Supplies ; Follow-Up Studies ; Humans ; Ligation ; Male ; Subclavian Artery

PURPOSE: Neoadjuvant chemotherapy is commonly used to treat cancer patients as adjunct treatment, but if the microvascular tissue transfer is performed simulataneously with cancer resection surgery, the induction chemotherapy might affect the survival rate of vascularized free flap. Our study will focus on the effect of induction chemotherapy on the free flaps which were made on white rat abdomen after injection of 5-FU. MATERIALS AND METHODS: The experimental rat groups were divided into three groups (total 24 rats) as a normal control group, 24 hrs group after 5-FU injection, 3 days group after 5-FU injection. Inferior abdominal island flaps of 8 Sprague Dawley rats on each group were made and immediately were induced into an ischemic state by clamping the supplying inferior epigastric artery and vein with microvascular clamp for a hour to induce a similiar free flap circumstance, then the inferior abdominal skin flaps were reperfused by releasing the clamps. The flaps on abdomen were repositioned and sutured. The experimental data for flap survival rate was collected by digital photo taking, analysed by computer image program to compare with the flap luminosity. The rats were sacrificed at 3 days, 5 days, 7 days after flap preparation and specimens of the flap were taken and stained with H-E staining. The microscopic finding was made under magnification of 200 and 400. RESULTS: 1. Gross findings on each groups showed the healing condition was good as following sequences; normal, 24 hrs group after chemotherapy, 3 days group after chemotherpy. 2. The values of flap luminosity for evaluation of flap survival rate also showed the same sequences as gross findings of healing state. 3. The microscopic findings of epidermis necrosis, inflammation state, dermis fibrosis, vessel change, fatty tissue layer thinning were compared with each group. The 3 days group after chemotherapy showed remarkably poor healing condition compared to other groups. CONCULSION: Chemotherapy agents affected the healing process of free flap, but healing condition was recovered spontaneously as post-injection periods passed out. In opposite to our expectation, 3 days group showed the bad flap condition in comparing with 24 hours group which was considered as immatured body circulation state of chemotherapy agent. It showed that 3 weeks in human being after chemotherapy was not proper as timing of microvascular tissue transfer if 3 days group in rat was considered as same healing period of 3 weeks in human being. More delayed healing timing than 3 weeks might be required in clinical application of free tissue transfer.
Abdomen ; Adipose Tissue ; Animals ; Constriction ; Dermis ; Drug Therapy ; Epidermis ; Epigastric Arteries ; Fibrosis ; Fluorouracil ; Free Tissue Flaps ; Humans ; Induction Chemotherapy* ; Inflammation ; Microsurgery* ; Necrosis ; Rats ; Rats, Sprague-Dawley ; Skin ; Surgical Flaps ; Survival Rate* ; Veins

Several microvascular anastomotic techniques have been described with methodical effectiveness, patency rates, healing state of microscopic findings. This experimental study presents the comparison of three types of arterial microvascular anastomotic techniques: end-to-end(ETE) anastomosis, end-in-end(EIE) anastomosis, and continuous technique. Sixty male Sprague-Dawley rats, 60 femoral arteries were used for this study. Twenty rats per each technique were used and sacrificed at post-operation 1 day, 3 days, a week, 2 weeks for scanning electromicroscopic findings. The patency was monitored by miniDoppler throughout total experimental periods. The anastomotic time on each method was measured to compare the technical effectiveness. The final results were as follows: 1. The anastomotic time for the end-in-end technique was significantly shorter than another techniques. The average time for each technique was measured as 15 minutes on EIE technique, 20 minutes on continuous technique and 25 minutes on ETE technique. 2. The patency rate for the end-in-end technique at 2 weeks also was superior to another techniques. The patency rate for each technique was demonstrated as 90 % on EIE technique, 85 % on ETE technique and 80 % on continuous technique. 3. The scanning electromicroscopic findings on healing condition of vessel endothelium during the observation period showed that the end results of EIE technique, ETE technique and continuous technique in sequence were good. The end-in-end technique proved to be the superior with regard to anastomotic time and patency rate when compared to end-to-end technuqe, so EIE techniqe might be well available for the case of large discrepancy of vessel size. The patency rate, microscopic healing findings in continuous technique were seen as the lowest level among the three anastomotic techniques, therefore the application of continuous technique was recommended only on the inevitable case.
Animals ; Endothelium ; Femoral Artery ; Humans ; Male ; Rats ; Rats, Sprague-Dawley

The purposes of this retrospective study were to assess the change of serum parameters in oral and maxillofacial surgery patients after operation and to determine what laboratory parameters on treatment periods were associated with the recovery of systemic condition. For purposes of assessing systemic nutritional status, several serum parameters were chosen. The sample patients were randomsubjects extracted from three category patient groups- oral cancer, odontogenic abscess, facial bone fracture based on treated patients at department of oral and maxillofacial surgery in Pusan National University Hospital from September 1, 1998, to September 1, 2002. Each groups were consisted with 10 patients. Each patient chart was examined and blood sample parameters were reviewed with clinical signs, symptoms and vital sign at preoperative day, postoperative 1 day, postoperative 1 week. Several parameters were analyzed statistically for extraction of mean values and differences between the periods groups. The findings of serum parameters of cancer, abscess and fracture groups were as follows: 1. In cancer patients, Hb, MCV, albumin, cholesterol, LDH, AST, ALT, neutrophil, platelet, leukocyte, Na, K, Cl, BUN, creatinine were analyzed. Values of Hb, albumin, AST, neutrophil, leukocyte, Cl showed significantly differences according to periods. 2. In abscess patients, CRP, ESR, leukocyte, body temperature, neutrophil were analyzed. Values of CRP, leukocyte, body temperature, neutrophil showed significanlty differences according to periods. 3. In fracture patients, same arameters with cancer patient's were chosen. Values of platelet, Cl only showed significantly differences according to periods. 4. In cancer patients, data regarding correlation was analyzed statistically as Pearson's value. A positive correlation was found between Hb and albumin, K, Na(p<0.05). A positive correlation was also found between neutrophil and leukocyte(p<0.05). Positive correlations were found between cholesterol and ALT, LDH and platelet, creatinine both, Platelet and BUN, Na and K(p<0.01). 5. In abscess patients, Peason's correlation values were analyzed on parameters. A positive correlation was found only between CRP and neutrophil(p<0.05). 6. In fracture patients, The correlations of parameters also were statistically analyzed. Positive correlations were found between MCV and K, albumin and LDH, AST and three parameters of creatinine, Na, Cl, K and neutrophil, neutrophil and three parameters of leukocyte, BUN, K(p<0.05). Positive correlations were found between LDH and AST, ALT and AST, creatinine both(p<0.01). This retrospective clinical study showed the CRP levels only on abscess patients may be useful in determination of clinical infected status, but the levels of other parameters on cancer, fracture patients did not showed significant values as diagnostic aids for clinical status.
Abscess ; Blood Platelets ; Body Temperature ; Busan ; Cholesterol ; Creatinine ; Facial Bones ; Humans ; Leukocytes ; Mouth Neoplasms ; Neutrophils ; Nutritional Status ; Retrospective Studies ; Surgery, Oral* ; Vital Signs