This report was a 10year retrospective study on mandible fractures. The study was based on a series of 245 patients who had been treated for mandibular fractures as in-patient at Yongsan Hospital of Medical college of Chung-Ang University during the period of Jan. 1987 to Dec. 1996. The results obtained are as follows; 1. In respect of incidence, the number of fractures was increased to 1990 and then it was decreased. The ratio of Men to Women was 6 : 1. 2. The major etiologic factors were traffic accident(30.2%), fisticuffs(28.6%), falldown(25.3%), accident related to work(7.8%), and sports(6.9%). In recent years, the decreasement of fractures due to traffic accident and the increasement of fractures due to sports was impressive. 3. The age frequency was highst in the third decade(44.9%), and second(%), fourth(%), decade in orders. In the first decade, the cause of fractures was traffic accident and falldown only, and the fractures due to sports were concentrated on second and third decade. 4. The frequent location of mandibular fractures was symphysis(36.1%), left angle(16.4%), right condyle(10.4%), right angle(8.6%), left condyle(8.6%), left body(5.8%), left ramus(4.0%), ramus(3.8%). The number of average fracture site was 1.62 at each patient and the number of average fracture line was 1.91 at each patient. 5. The simple fracture was 43.7%, and the complex fracture was 56.3%, then the open fracture was 35.5%, and the closed fracture was 64.5%. 6. In respect of treatment, the frequency of open reduction was 74.3% and that of closed reduction was 25.7%, but in the condyle, closed reduction(68.0%) was the more frequently using method of treatment than open reduction(32.0%). 7. The patients were treated an average of 3.27 days after injury and the average hospitalization period was 10.07 days. 8. The mandibular 3rd molar was existing in 60.6% of angle fractures.
Accidents, Traffic ; Female ; Fractures, Closed ; Fractures, Open ; Hospitalization ; Humans ; Incidence ; Male ; Mandible* ; Mandibular Fractures ; Molar ; Retrospective Studies* ; Sports

We report a case of eosinophilic pustular folliculitis in a 6-month-old male infant who had pruritic, tiny, erythematous papulopustules on his scalp and eosinophilia in the peripheral blood. Histopathologic examination revealed an acute follicu1ar and perifollicular inflammatory infiltrate with abundant eosinophils. The patient responded to systemic and topical corticosteroid and dapsone.
Dapsone ; Eosinophilia ; Eosinophils* ; Folliculitis* ; Humans ; Infant ; Male ; Scalp

BACKGROUND: In congenital heart disease, the lung perfusion through stenosed pulmonary artery is usually decreased. And this decrement of lung perfusion also occurs with diaphragmatic palsy after the operation of congenital heart disease. It is difficult to delineate the amount of lung perfusion in case of combination of pulmonary artery stenosis and diaphragmatic palsy. We examined the change of lung perfusion after the induction of diaphragmatic palsy in rabbits. METHODS: We dissected left phrenic nerves in 20 rabbits to induce left diaphragmatic palsy. The lung perfusion scan was performed with 99mTc-MAA and the movement of diaphragm was examined with fluoroscopy. They were performed as baseline data and on 3rd and 10th day postoperatively. The amount of left lung pefusion before and after diaphragmatic palsy was compared and analysed in 12 rabbits which definitely had diaphragmatic palsy. RESULTS: Weight of the rabbits was 1.65+/-0.26 kg. Left lung perfusion percent was 45.93+/-6.42% before operation and these were 32.48+/-6.09% and 37.62+/-3.39% on the 3rd and 10th postoperative day, respectively. Left lung perfusion was significantly decreased just after diaphragmatic palsy but it was not changed thereafter. The decrement of lung perfusion was not affected by the body weight. The decreased amount of left lung perfusion was reciprocally correlated with the body weight of the rabbits on the postoperative 3rd day but not 10th day. CONCLUSION: Left lung perfusion percent of the rabbits was decreased 7% with the induction of diaphragmatic palsy and the decreased amount was reciprocally correlated with the body weight just after the diaphragmatic palsy was induced.
Body Weight ; Constriction, Pathologic ; Diaphragm ; Fluoroscopy ; Heart Defects, Congenital ; Lung* ; Paralysis* ; Perfusion* ; Phrenic Nerve ; Pulmonary Artery ; Rabbits

No abstract available.
Decompression* ; Head* ; Osteonecrosis*

No abstract available.
Child* ; Humans ; Radioisotope Renography*

"Pseudosarcomatous change" occurs when sarcoma-like atypical cell hyperplasia is grossly indistinguishable from malignant tumor. Pseudosarcoma often exists in those areas of the gastrointestinal track where ulcer or erosion commonly takes place. This may indicate atypical granulomatous cell proliferation during a period of healing, as well as benign atypical change in the mesenchyme due to chronic inflammatory reaction. Both the visual appearance and intestinal involvement of tuberculous colitis are variable, and tuberculosis may result in reactive mesenchymal change associated with ulcer or polyp, which is that's induced by chronic inflammation. We report here on a case of a young female pulmonary tuberculosis patient who suffered with a pseudosarcoma of the ascending colon, and this was associated with tuberculous colitis. The patient underwent successful sugical resection. We report on this case, along with a review of the relevant literature.
Cell Proliferation ; Colitis* ; Colon* ; Colon, Ascending ; Female ; Humans ; Hyperplasia ; Inflammation ; Mesoderm ; Polyps* ; Tuberculosis ; Tuberculosis, Pulmonary ; Ulcer

No abstract available.
Antibodies*

Cutaneous metastasis from renal cell carcinoma is unusual and have been reported infrequently. We report a case of metastatic renal cell carcinoma in a 33-year-old man who presented with a 3.5X2.0 cm-sized round, brightly red colored nodule on the scalp for 1 month. A skin biopsy revealed the typical clear cell adenocarcinoma with clear cytoplasm and oval hyperchromatic nuclei arranged in glandular pattern consistent with metastatic renal cell carcinoma. In most instances, once cutaneous involvement is manifested the disease is widespread and has a poor prognosis. But, our case presented only a single cutaneous nodule, and workup showed no evidence of further metastasis for 1 year.
Adenocarcinoma, Clear Cell ; Adult ; Biopsy ; Carcinoma, Renal Cell* ; Cytoplasm ; Humans ; Neoplasm Metastasis ; Prognosis ; Scalp* ; Skin

Keratocystic odontogenic tumors (KCOT) - previously termed odontogenic keratocysts (OKC) - are characterized by aggressive behavior and a high rate of recurrence. Histopathologically, the basal layer of KCOT shows a higher cell proliferation rate and increased expression of anti-apoptosis genes. Clinically, KCOT is frequently involved in the mandibular posterior region but is not common in the posterior maxilla. However, it should be noted that due to its expansive characteristics, KCOT involved near the maxillary sinus could easily expand to an enormous size and occupy the entire maxilla. To achieve total excision of these expanded cystic tumors in the maxilla, a more aggressive approach would be needed. In this report, we describe two cases of expansile KCOT involving the entire unilateral maxilla and maxillary sinus; they were completely excised using the Weber-Ferguson approach, showing no evidence of recurrence during the follow-up period of more than two years. In immunohistochemical analyses of the tumor specimens, p53 and p63 showed strong expression, and B-cell lymphoma 2 (BCL2) and MKI67 (Ki-67) showed moderate or weak expression, however, detection of BCL2-associated X protein (BAX) was almost negative. These data indicate that expansile KCOT possesses increased anti-apoptotic activity and cell proliferation rate but decreased apoptosis. These properties of KCOT may contribute to tumor enlargement, aggressive behavior, and high recurrence rate.
Apoptosis ; bcl-2-Associated X Protein ; Cell Proliferation ; Follow-Up Studies ; Immunohistochemistry ; Lymphoma, B-Cell ; Maxilla ; Maxillary Sinus ; Odontogenic Cysts ; Odontogenic Tumors ; Recurrence

BACKGROUND: Moisturizers with anti-inflammatory or anti-itch activity should be developed for the safe and effective management of atopic dermatitis (AD). OBJECTIVE: This study evaluated the efficacy of a newly developed moisturizer, CSP0510 lotion (Twolines Inc., Korea), containing citric acid (CA) and trisodium phosphate (TSP) as active ingredients, in mild to moderate AD. METHODS AND RESULTS: CSP0510 lotion applied twice daily for 4 weeks to eczematous lesions improved objective and subjective (itch) symptoms of AD. The physician's global assessment (PGA) score for objective symptoms decreased from 2.5±0.6 before application to 1.3±0.5 after application in the CSP0510-treated group (n=42, p<0.001). Also, the PGA score decreased from 2.3±0.6 to 1.9±0.5 by vehicle-treated (without CA and TSP) control group (p=0.001), but there was no statistical difference between CSP0510-treated and vehicle-treated groups (p=0.089). The visual analogue scale score for itch decreased from 4.8±1.3 to 2.0±0.9 in the CSP0510-treated group (p<0.001), and from 4.6±1.1 to 3.5±0.9 in the control group (p=0.075), showing a statistical significance between two groups (p=0.002). Our results in humans were further supported by in vitro and animal experiments. In HaCaT cells treated with compound 48/80 (7.5 µg/ml), CA:TSP (1:1, vol:vol) synergistically suppressed the compound 48/80-induced upregulation of thymic stromal lymphopoietin, nerve grow factor, and calcitonin gene-related peptide. Application of CSP0510 to the dorsal skin of hairless mice for 3 weeks suppressed the oxazolone-induced allergic skin inflammation. CONCLUSION: In conclusion, CSP0510 lotion has anti-itch and anti-inflammatory activity in the skin, which improves both objective and subjective symptoms of AD.
Animal Experimentation ; Animals ; Anti-Inflammatory Agents ; Calcitonin Gene-Related Peptide ; Citric Acid* ; Dermatitis, Atopic* ; Humans ; In Vitro Techniques ; Inflammation ; Mice ; Mice, Hairless ; Skin ; Up-Regulation