1.Vertigo in vertebrobasilar insufficiency and vascular structural abnormality
Yu LIAO ; Wei JIANG ; Jun ZHOU
Chinese Journal of Tissue Engineering Research 2006;10(36):178-180,插2
BACKGROUND: Nowadays, it is reported that vessel structural abnormity is the main morphological basis of vertigo due to vertebrobasilar arterial insufficiency abroad, but the report of vascular structural abnormality in vertebrobasilar arterial insufficiency is rare at home.OBJECTIVE: To observe the manifestation and clinical significance of vessel structural abnormity tested by digital substraction angiography (DSA)in patients with vertigo induced by vertebrobasilar arterial insufficiency.DESIGN: Case analysis.SETTING: Department of Neurology, Wuxi Second Hospital (Wuxi Municipal Second People's Hospital) Affiliated to Nanjing Medical University and Department of Neurology, Huaihua Hospital Affiliated to Nanhua University.PARTICIPANTS: A total of 57 patients, who were diagnosed as having episodic vertigo with or without nausea or vomiting, and hospitalized in the Department of Neurology, Huaihua Hospital Affiliated to Nanhua University from August 2003 to May 2004 and Wuxi Second Hospital (Wuxi Municipal Second People's Hospital) Affiliated to Nanjing Medical University between October 2004 and May 2005, were enrolled.METHODS: Fifty-seven patients with vertigo induced by vertebrobasilar arterial insufficiency hospitalized in the recent two years were treated with digital subtraction radiography in aortic arch and aortocranial angiography:Applying retrograde angiography of femoral artery puncture, Optiray nonionic contrast agent with syringe pattern to perform aortic arch angiography. Digital subtraction machine displayed bilateral carotid artery, vertebral artery, ranged from carotid artery to siphon of carotid artery from multiple angles. Measurement and evaluation were conducted by 2 doctors from department of neurology.MAIN OUTCOME MEASURES: Type, distribution and proportion of vesselstructural abnormity of aortic arch, carotid artery and vertebrobasilar system.RESULTS: Of the 57 patients, 1 patient was dropped out, because the left vertebral artery (LVA) could not be entered. A large area cerebral infarction was occurred in another patients during aortic arch angiography was performed, and the operation was stopped. Totally 55 patients were involved in the result analysis. It was found that 71%(39/55) of patients had vessel structural abnormity in cervical part and intracalvarium, 11%(6/55)of patients with simple anterior circulation lesion, 60% (33/55) of patients with posterior circulation lesion, of which 9 cases (16%) with compound lesion of anterior circulation abnormity. Two or above vessels in 24 cases (24/55,44%) were involved. Vertebral artery complicated with other angiostegnosis was the most common, and there was no vessel structural abnormity in other 16 cases (16/55,29%).CONCLUSION: Various types of vessel structural abnormity are the main etiological factors of vertigo induced by vertebrobasilar arterial insufficiency. Gold standard of diagnosing vertigo due to vertebrobasilar arterial insufficiency is DSA.
3.Research progress of targeted degradation of Mycobacterium tuberculosis proteins
Acta Pharmaceutica Sinica 2023;58(5):1221-1231
Tuberculosis (TB), an infectious disease caused by
4.Clinical application of acellular dermal matrix to repair the defect of oral mucosa.
Jie CHEN ; Wei WEI ; Jian-Jun YU
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2007;42(11):860-861
Adult
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Aged
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Dermis
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transplantation
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Female
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Humans
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Male
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Middle Aged
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Mouth Mucosa
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pathology
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Reconstructive Surgical Procedures
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methods
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Wound Healing
5.Toxicity tests of Magnolia biondii Pamp volatile oil nanometer bangosome
wei-wei, LU ; min, WU ; zheng-jun, XI ; jun-yu, YAO
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(06):-
Objective To investigate the acute toxicity, subacute toxicity, nasal membrane local toxicity of the Magnolia biondii Pamp volatile oil nanometer bangosome. Methods Kunming mice and SD rats were selected as experimental material. Kunming mice were used in the acute and subacute toxicity tests by intragastric administration of Magnolia biondii Pamp volatile oil nanometer bangosome with different dosage and different time, and SD rats were used in the nasal membrane local toxicity test by nose dropping, while the control group was treated with intragastric administration of or nose dropping with normal saline for the same dosage. The treatment course lasted fifteen days. At the end of the tests, the general condition, routine blood test, function index of live and kidney, organ humid weight index, histological changes of liver and kidney and ultra microstructure change of rat nasal membrane were obtained and compared with the control group. Results In the acute toxicity test, the daily maximum tolerant dosage by intragastric administration was equal to 222.7 times of the clinical routine, with no marked toxic reaction. In the subacute toxicity test, the general condition, blood test, organ humid weight index and histological changes of live and kidney in different dosage groups were similar to the control group. While in the function index of live and kidney, uric acid was stepped down in the middle and large dose groups, and total bilirubin was decreased in the large dose group. The nasal membrane local toxicity test revealed that there was little change in the ultra microstructure of rat nasal membrane.Conclusion The Magnolia biondii Pamp volatile oil nanometer bangosome may have little toxicity by intragastric administration and nose dropping.
9.Nasal septal perforation combined with chronic invasive fungal rhinosinusitis: three cases report.
Hua-ming ZHU ; Wei-tian ZHANG ; Yu-jun ZHANG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2012;47(8):692-693
Aged
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Humans
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Male
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Middle Aged
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Mycoses
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complications
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Nasal Septal Perforation
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complications
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microbiology
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Sinusitis
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complications
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microbiology
10.Clinical analysis on reoperation on differentiated thyroid cancer.
Zhen-yu WANG ; Feng LI ; Wei-jun ZHANG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2010;45(11):951-953
Adult
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Aged
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Carcinoma, Papillary
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pathology
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surgery
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Female
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Humans
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Male
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Middle Aged
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Reoperation
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Retrospective Studies
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Thyroid Neoplasms
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pathology
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surgery
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Treatment Outcome
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Young Adult