2.Advance in Virtual Reality Rehabilitation Technique in Upper Limbs Motor Function of Stroke Patients (review)
Ling JIN ; Tong ZHANG ; Jun ZHAO
Chinese Journal of Rehabilitation Theory and Practice 2014;(10):905-907
This paper briefly introduced the characteristics, some kinds of equipment, and the advantages of virtual reality technology in rehabilitation, especially in upper limb function rehabilitation, and its mechanism of motor function recovery after stroke. Some assessment tools commonly used for motor function were summarized.
3.Effects of Dysphagia on Nutrition in Stroke Patients
Bingjie LI ; Tong ZHANG ; Jun ZHAO
Chinese Journal of Rehabilitation Theory and Practice 2011;17(3):262-264
ObjectiveTo investigate the influence of dysphagia on nutritional status of stroke patients. MethodsSwallowing function of stroke patients were studied with videofluoroscopy. They were divided into study group and control group according to the results of videofluoroscopy (60 cases in each group). Their nutritional status were compared. ResultsThe triceps skin fold, mid-upper arm muscle circumference and serum albumin in the study group were lower significantly than those in the control group (P<0.05). ConclusionDysphagia is associated with poor nutrition in stroke patients.
4.The therapeutic effects of constraint-induced movement on patients with upper extremity disorders after head injury
Jun ZHAO ; Tong ZHANG ; Bingjie LI ; Yan ZHANG ; Zhijun HUANG
Chinese Journal of Physical Medicine and Rehabilitation 2003;0(11):-
Objective To investigate the therapeutic effects and relative mechanisms when constraint-induced movement therapy (CIMT) is used in patients with upper extremity disorders after head injury, and to compare the effects of CIMT with those of traditional rehabilitation (TR). Methods Thirty-six hemiparesis patients were randomly divided into a CIMT group and a TR group. Patients in the CIMT group were treated with intensive shaping training for 5 h a day for 3 weeks, as well as having their unaffected arms constrained. Meanwhile, the patients in the TR group were treated with traditional rehabilitation with no constraint of their unaffected arms. Motor activity logs (MALs) were compiled, and the Wolf Motor Function Test ( WMFT) and Barthel Index ( BI) were used to evaluate the therapeutic effects before treatment and at 0 d, 1 month and 3 month after treatment. Results Compared with the scores before treatment, the therapeutic effects were significant in the CIMT group, and the effect lasted to the follow-up period. Significant differences were also found between the CIMT group and the TR group in the improvement of dexterity by means of WMFT, and the usage of unaffected upper extremity as recorded in the MAL. There were no significant differences in therapeutic effects between the 2 week and 3 week treatments in the CIMT group. Conclusion CIMT significantly improved upper extremity function and ability in the activities of daily living ( ADL) of hemiplegia patients in the subacute period. The effectiveness of CIMT is superior to that of traditional rehabilitation methods.
5.A clinical comparison of complete re-flow with partial re-flow on offectioh of Patients with MI accompany with HF's LVSF.
Tong ZHANG ; Jun YANG ; Xiang ZHANG ; Al ET ;
Chinese Journal of Practical Internal Medicine 2006;0(S1):-
Objective To explore the different effects of patiants with Myocardial infarction(MI)accompany with HF's LSVF and the prognosis between complete reftow and partial reflow.Methods 57 cases with MI accompany with HF were randomly divided into 2 groups:complete reflow group and partial reflow group.The two groups were done low-dose Dobutamine loading experiment seperately before operations.22 cases were treated by complete tallow using PCI,other 35 Patients were dealed with Partial reflow using PCI.To contrast the data of LVSF,WMSI,A/V and LVED between the two groups with UCG before and after PCI.Results The complete reflow group was obviously more arailable than the partial group.Conclusion The complete reflow can improve LVSF of the paticnts with MI accompany with HF.
6.Peripheral blood stem cell transplantation in the treatment of dilated cardiomyopathy: A 3-month follow-up in 42 cases
Tong ZHANG ; Chao LIU ; Jun YANG ; Xiang ZHANG ; Wen LI
Chinese Journal of Tissue Engineering Research 2007;0(16):-
AIM: Recent studies showed that stem cells could replace injured cardiomyocyte and increase the number of functional cardiomyocytes. Researching the pertinent literature in China Journal Full-text Database (CJFD) published between 2005 and 2008 indicated that the researches on stem cell transplantation in the treatment of primary dilated cardiomyopathy were few. This study investigated the therapeutic efficacy and security of peripheral blood stem cell transplantation in coronary artery in treatment of dilated cardiomyopathy and its effects on left ventricular function. METHODS: Forty-two patients with dilated cardiomyopathy between December 2006 and September 2007 were enrolled at the Department of Cardiology of First People's Hospital of Yunnan, including twenty-eight males and fourteen females, averagely aged (56?3) years. Inclusive criteria: patients with less than 65 years, left ventricular enlargement, and left ventricular ejection fraction (LVEF) ≤ 45%, and without coronary artery disease after coronary arteriongraphy. Informed consents were obtained from patients. Patients were divided into stem cell transplantation group (n=15) and control group (n=27) on the basis of whether being treated by stem cell transplantation. Patients in the stem cell transplantation group were consecutively administered granulocyte colony-stimulating factor (G-CSF) by hypodermic injection to stimulate bone marrow stem cells themselves based on conventional treatment for five days. Peripheral blood stem cell suspension was disassociated on the 6th day, and the collected suspension was injected into left anterior descending branch over the wire saccule tube for autologous peripheral blood stem cell transplantation. Patients in the control group were administered by conventional treatment of dilated cardiomyopathy. Security and adverse reaction were observed during the mobilization, collection and returning injection of peripheral blood stem cell by coronary artery. Morphous, cardiac function and motion index of left ventricle wall were evaluated using ultrasoundcardiogram before and 3 months after transplantation. Survival rate and incidence rate of heart incidents were compared. RESULTS: Three months after stem cell transplantation in coronary artery, there were a significant decrease in cardiac end-systolic volume (ESV), cardiac end-diastolic volume (EDV) and motion index of left ventricle wall, but a significant increase in LVEF(P
7.Effect of Constraint-Induced Movement Therapy on Improving the Flexibilty of Upper Extremities and the Ability of Daily Living of Patients With Hemiplegia
Jun ZHAO ; Tong ZHANG ; Yan ZHANG ; Bingjie LI
Chinese Journal of Rehabilitation Theory and Practice 2006;12(11):947-949
ObjectiveTo investigate the effect of constraint-induced movement therapy(CIMT) on improving the flexibilty of upper extremities and the ability of daily living(ADL) of patients with hemiplegia.Methods36 patients with hemiparesis were randomized to two groups: CIMT and traditional rehabilitation(TR).In CIMT group,18 patients received intensive shaping training of 5 h/d,lasting 3 weeks, with the constraint of unaffected arms.In TR group,patients received traditional rehabilitation in the same times,without the constraint of unaffected arms. They were evaluated with Action Research Arm(ARA) Test and Barthel Index(BI) before intervention,immediate after intervention,4 and 12 weeks after intervention respectively.Patients in CIMT group were also evaluated with ARA tests 2 and 3 weeks after training.ResultsSignificant difference was found between CIMT and TR group on the improvement of ARA test(P<0.05).There was no significant difference between 2 and 3 weeks after training in CIMT group.Significant difference in BI was also found in CIMT group(P<0.01),but has not been found between CIMT and TR group.ConclusionCIMT significantly improved the flexibilty of upper extremities and ADL of patients with hemiplegia,which is superior to the traditional rehabilitation.
8.Effect of Traditional Chinese Drug Combined with Training of Musculus Quadriceps Fexoris on Knee Osteoarthritis
Tong SI ; Su-jie ZHANG ; Jin-jun ZHANG
Chinese Journal of Rehabilitation Theory and Practice 2008;14(12):1194-1196
Objective To observe the effect of traditional Chinese drug combined with training of musculus quadriceps fexoris on knee osteoarthritis(KOA).Methods70 out-patient clinic KOA patients were divided randomly into the Chinese drug group and control group with 35 cases in each group.The Chinese drug group was treated with Shentongzhuyu medicinal broth PO bid;the control group was treated with Sulindac 0.2 g PO bid.Two groups were combined with the training of musculus quadriceps fexoris,having 10 times per course and 3 courses in total with a 3 days interval between two courses.The therapeutic effect was evaluated with footplate pressure gait analysis and modified JOA marks.ResultsAfter treatment,the effect of the Chinese drug group was superior to the control group(P<0.05),especially 12 weeks post treatment.There maximum weight loading,time integral and weight loading intergral of affected limb of the Chinese drug group significantly improved after treatment(P<0.01),but for the control group,only weight loading intergral improved(P<0.05).ConclusionTraditional Chinese drug combined with training of musculus quadriceps fexoris has better curative effect on the pain and functional disturbance of KOA.
9.Effects of moderate and small intensity exercise on corticosterone and interleukin-2 in serum and T lymphocyte subgroups in plasma of rats under repeated psychological stress
Zaining ZHANG ; Jianchun YIN ; Jun YAN ; Zhaogang TONG
Chinese Journal of Tissue Engineering Research 2005;9(44):190-192
BACKGROUND: The increasingly deepened studies have proved that moderate exercise training can effectively cope with the psychological and physiological stress, and improve the immunological functions of the body.OBJECTIVE: To observe the effect of exercise on the patients in pschoneuroimmunology.DESIGN: A randomized controlled observation.SETTING: Huaiyin Teachers College and the School of Physical Education of Yangzhou University.MATERIALS: The experiment was carried out at the Laboratory of Exercise Biochemistry of the School of Physical Education of Yangzhou University between September and November 2002. Fifty-four male SD rats were randomly divided into quiet control group (n=8), psychological stress group (n=8), stress plus 30-minute exercise group (n=7), stress plus 60-minute exercise group (n=8), 30-minute exercise group (n=7), 60-minute exercise group (n=8), shock group (n=8).METHODS: Quiet control group: There was neither exercise nor stress.Shock group: No exercise was involved, and shock was used as the source of stimulation in the stress group. Psychological stress group: The rats under stress did not receive shock, but just watched the process of shock in the shock group as bystanders in order to produce psychological stress through visual sense and hearing sense. Each stress lasted for 30 minutes,once every other day for 2 continuous weeks. 30-minute exercise group: In the first week, the rats adapted to training for 10 minutes every day, and then they swam without load for 30 minutes once a day for 8 weeks. 60minute exercise group: In the first week, the rats adapted to training for 30minutes every day, and then they swam without load for 60 minutes once a day for 8 weeks. Stress plus 30-minute exercise group: The rats received the same exercise as that of the 30-minute exercise group and the same stress as that applied to the psychological stress group. Stress plus 60-minute exercise group: The rats received the same exercise as that of the 60-minute exercise group and the same stress as that of the psychological stress group. The contents of corticosterone and interleukin-2 in serum were detected with radioimmunoassay, and the number of T lymphocyte subgroups was determined with the method of enzyme labeling.MAIN OUTCOME MEASURES: ① Effects of exercise of moderate and small intensity on serum corticosterone and interleukin-2 of stress rats. ②Effects of exercise of moderate and small intensity on T lymphocyte subgroups of CD3+, CD4+ and CD8+ in stressed rats.RESULTS: ①Effects of exercise of moderate and small intensity on serum corticosterone and interleukin-2 of stress rats: The serum levels of interleukin2 in stress rats were significantly lower than that of the rats in the control group, and the serum contents of corticosterone were significantly higher than that in the control group. The serum levels of interleukin-2 in the exercise group were significantly higher than that in the control group, and the serum contents of corticosterone were significantly higher than that in the control group. Compared with stress group, the level of interleukin-2 was significantly higher and the contents of corticosterone were markedly lower in the stress plus 30-minute exercise group and stress+60-minute exercise group. ② Effects of exercise of moderate and small intensity on T lymphocyte subgroups of CD3+, CD4+ and CD8+ in stress rats: Compared with the control group, the numbers of T lymphocyte subgroups were all significantly in the 30 and 60minute exercise groups. Compared with the stress group, the levels of CD3+and CD4+ in the stress plus 60-minute exercise group were significantly higher than thosein the stress group. The CD4+/CD8+ level had no significant difference between the stress plus 30-minute exercise group and stress group, but not lower than those in the stress group.CONCLUSION: Repeated psychological stress caused greater psychological response from rats, and inhibited the immnological function, and exercise of moderate and small intensity had better protective effect on the immunological function of rats under psychological stress, and the exercise of moderate intensity much more greatly improved the anti-stress ability of rats. The possible mechanism lies in the fact that exercise of moderate and small intensity produced better adaptability for hypothalamic-pitutiary-adrenal axia, changed the in vivo excretion of stress hormone, and then maintained the stability of immunological function.
10.Effect of Virtual Reality Rehabilitation on Balance Function in Stroke Patients with Hemiplegia
Ran SUN ; Tong ZHANG ; Jun ZHAO ; Lixu LIU
Chinese Journal of Rehabilitation Theory and Practice 2014;(5):458-463
Objective To compare the effect of virtual reality (VR) based balance training and routine balance training on static and dynamic balance function in stroke patients with hemiplegia. Methods 20 stroke patients with hemiplegia were randomly divided into experimental group (n=10) and control group (n=10). Both groups received routine neurology medication and rehabilitation training. The experimental group received balance training based on 3 VR games: City Ride, The Boat and Road Encounter, while the control group received routine balance training. They were assessed with Berg Balance Scale (BBS) and Timed Up and Go Test (TUGT), and their postural stability and limits of stability were measured with STABLE system before and 4 weeks after training. Results The scores of BBS and TUGT improved in both groups after training (P<0.001), and improved more in the experimental group than in the control group (P<0.001), as well as some of the parameters of postural stability and limits of stability (P<0.05). Conclusion Balance training based on VR is more effective than routine balance training on the static and dynamic balance function of stroke patients with hemiplegia.