[Objective] To compare the clinical cure effects of different operations on myomectomy, and screen out best clinical treatment for hysteromyoma in child-bearing period. [Method] Trace back and analyse 200 cases of such patients, divide them into laparotomy group, laparoscope group, vaginal group and UAE group under different therapies, compare cure effect analysis. [Result] On operation time, operation bleeding and evacuation time, the UAE group ,vaginal and laparoscope groups were successively better than the laparotomy group; but on post-operation medication rate and average in-hospital days, the UAE group was successively less than laparoscope, vaginal and laparotomy groups. On complication rate,the laparoscope was successively less than UAE, vaginal and laparotomy groups.[Conclusion] 4 therapies have respective advantages, UAE and laparoscope myomectomy have little trauma, quick re-covery and reliable cure effect, however, laparotomy can't be completely replaced owing to its wide indications.

Objective:The purpose is to observe the clinical results of the continuous douche and negative pressure drainage technic in treating the large hypodermal infected lacuna. Methods: The simple mini-size perfusion cannula for continuous douche and negative pressure drainage was handmade and used on 23 patients suffering from large hypodermal infected lacuna. Results: All of the 23 patients achieved primary healing from large hypodermal infected lacuna. Conclusion:The use of self-made mini-size perfusion cannula for continuous douche accompanied with negative pressure drainage is a good method to treat large hypodermal infected lacuna. It is very economic、efficient and easy.

Amyloid beta-Peptides ; toxicity ; Animals ; Drugs, Chinese Herbal ; pharmacology ; Estradiol ; pharmacology ; PC12 Cells ; Peptide Fragments ; toxicity ; Rats

Angiotensin I ; pharmacology ; Animals ; Blood Pressure ; drug effects ; physiology ; Infusions, Intraventricular ; Male ; Peptide Fragments ; pharmacology ; Pulmonary Artery ; physiology ; Rats ; Rats, Sprague-Dawley

Objective: To explore a proper way of building hospital's NICU visit system. Methods: Compare and analyze existing NICU visit systems, put forward the approach of HD mobile video visit system in NICU. Design and develop a visit system consists of visiting cart, HD video capturing subsystem, image acquisition and transmission software, wireless HDMI receiving and monitor system and intercom system. Apply the method and analyze the effect of the visit system. Results: The mobile video visit system can avoid direct contact between parents and neonatal to prevent cross-infection, in the same time, the system has shown the hospital's humanistic care for parents, and that will help to establish a harmonious doctor-patient relationship. Conclusion:The HD mobile video visit system is a new effective choice for hospital's NICU visit systems, and it will be good clinical significance.

Objective To explore the role of serum levels of Klotho protein and fibroblast growth factor(FGF)-23 in patients with chronic kidney disease(CKD).Methods A total of 160 patients with CKD were recruited into CKD group in this study,160 healthy controls were selected in the control group from March 2014 to March 2016.Basic clinical data,blood biochemical index,serum level of Klotho protein and FGF-23 were analyzed and compared between the two groups.Results The hemoglobin,serum albumin,blood calcium,glomerular filtration rate,Klotho protein levels in the CKD group were lower than those in the control group,and the serum creatinine,blood urea,blood serum phosphorus and FGF-23 were higher than those in the control group(P<0.05).With the progress of CKD stages,hemoglobin,glomerular filtration rate,Klotho protein levels gradually decreased,serum creatinine,blood urea,blood serum phosphorus,FGF-23 level increased(P<0.05).The levels of FGF-23 were negatively related to hemoglobin,glomerular filtration rate,Klotho(r=-0.584,0.692,-0.724)and were positively correlated to serum creatinine,blood urea,blood serum phosphorus(r=0.814,0.703,0.527).The levels of Klotho protein were positively related to hemoglobin,glomerular filtration rate(r=0.612,0.685),and were negatively correlated to serum creatinine,blood serum phosphorus,blood urea,FGF-23(r=-0.720,-0.690,-0.519,0.724).Conclusion High concentrations of FGF-23 and Klotho protein with low concentration were not only related to calcium phosphate metabolic disorders of patients with CKD,and were also associated with the prognosis of patients with CKD,which might be early biomarkers and predictor in patients with CKD.

Objective To compare the influences of different routes of nutrition on the outcome and respiratory muscle strength of elderly patients in respiratory intensive care unit (RICU). Methods Totally 147 elderly patients in RICU were equally randomized into combined nutrition group ( combinination of parenteral nutrition and enteral nutrition), total enteral nutrition (EN) group, and total parenteral nutrition (PN) group. The changes of energy metabolism, respiratory muscle strength, and short-term outcome were observed or determined.Results Plasma albumin (ALB), hemoglobin (Hb), creatinine (Cr) levels, and nitrogen balance significantly increased in all group 7 days later ( all P ＜ 0. 01 ), while blood urea nitrogen (BUN) significantly decreased ( P ＜0.01 ). The increase of ALB, Hb, Cr levels, and nitrogen balance were significantly more remarkable than that in EN group and PN group (P＜0.05 or P＜0.01). The decrease of BUN level in the combined nutrition group was significantly more remarkable than that in EN group ( P ＜ 0. 05 ). After nutritional support, the maximum inspiratory pressure in the combined nutrition group (P =0. 021 ) and EN group (P = 0. 011 ) became significantly higher, and occlusion pressure at 0.1 second inspiration level in the combined nutrition group became significantly lower ( P =0. 025). The incidences of infectious and non-infectious complications in PN group were significantly higher than those in EN group (P = 0. 002 and 0. 017, respectively) and combined nutrition group ( P = 0. 005 and 0. 004, respectively). Gastric retention was more common in EN group than that in PN group ( P = 0. 035). The weaning time,length of RICU stay, length of hospital stay and 20-day-mortality were significantly decreased in the combined nutrition group than those in the other two groups ( all P ＜ 0. 05 ). Conclusion The effectiveness of the combined application of PN and EN is superior to PN or EN alone in improving nutritional status and respiratory muscle strength as well as in improving the short-term outcome in elderly patients in RICU..

Objective To investigate the therapeutic effect of Shenmai injection(SMI)on neonatal hypoxic-ischemic encephalopathy(HIE)and it's possible mechanism.Methods 45 neonates with HIE were randomly divided into the SMI treatment group and routine treatment group.At the basic of routine treatment,the SMI treatment group was treated with 10 ml SMI added into 10% GS 30~50 ml via injecting into veins once a day for 7~10 d.The levels of serum S-100?,NSE were measured at 1 d,3 d,6 d after treatment.The development quotients(DQ)was evaluated at 3-month-old infants.Results Compared with routine treatment group,symptoms of nervous system in SMI treatment group were recovered obviously faster,the hospitalization time was shorter(all P

Objective: To investigate the relationship between anemia and severity of coronary artery lesions.Methods: A total of 227 consecutive patients with coronary artery disease(CAD) were studied.According to their hemoglobin levels,all patients identified positive by selective coronary angiography(CAG) were divided into two groups,anemic group and non-anemic group,their clinical types and severity of coronary artery lesions were compared.Results: The proportion of anemia in unstable angina and infarction group was higher than those in stable angina group,similarly the proportion of anemia was also high in severe stenosis,occlusion and three-branch stenosis groups than that in other groups.Conclusion: Anemia is possibly one of the predictive factors suggesting CAD's clinical types and deterioration of coronary artery stenosis.

Objective: Various quantitative assessments of coronary heart disease(CHD) risk factors was performed to evaluate severity and predicting its occurrence rate.Methods:282 cases,were selected to be scored by Framingham,PROCAM(The Prospective Cardiovascular Munster Study) and Chinese risk scores respectively.We compared the relationship between three risk scores and severity,extent of coronary artery through correlation analysis,and subsequently analyzed their predictive value.Results: Chinese risk score,PROCAM risk score,Framingham risk score were significantly correlated with extent and severity of coronary artery atherosclerosis(CAAS),with PROCAM risk score,the highest correlation of it and Framingham risk score,the smallest.Risk scores increased with coronary artery pathological change advancing.The areas under resident operation character(ROC) of Framingham risk score was the least,whereas that of PROCAM was the largest.Conclusion: Among the three risk scores described above used to evaluate the severity of CAAS and predict incidence of CHD,PROCAM risk scores was the superior.