1.Psychological Intervention for Family of Children with Hematological Tumor
Jun HU ; Daguang CHEN ; Yanhui CHEN
Chinese Mental Health Journal 2002;0(12):-
Objective: To explore the functions of psychological intervention in the integrative therapy for children's hematological tumor. Methods: The psychological status of 52 children with hematological tumor and their parents, and 48 healthy children and their parents were measured by means of the self-compiled psychological status scale and the symptom checklist 90 (SCL-90). Moreover, 26 children with hematological tumor and their parents, who were drawn out in random, were done by psychological intervention of 3 months as well as chemotherapy, and then their psychological status were evaluated. Results: The psychological problems were more prevalent in children with hematological tumor and their parents than those in the healthy children and their parents. Among the total, the problems of social behavior (3.9?2.9), personal emotion (7.1?4.7), habit (1.2?1.1), and learning (1.3?1.2) in the children with hematological tumor were more than those(1.5?1.6, 1.5?2.0, 0.5?0.7, 0.4?0.5) in the healthy children(P
3.Application of Event Related Potentials in the Integrative Intervention for Attention Deficit Hyperactivity Disorder in Children
Qiujun LIN ; Jun HU ; Shan CHEN
Journal of Chinese Physician 2001;0(04):-
Objective To explore the application of event related potentials (ERPs) in the comprehensive intervention for attention deficit hyperactivity disorder (ADHD) in children. Methods P 300 of ERPs and Conners' measuring scale were tested in 31 children with ADHD before and 6 months after comprehensive intervention. At the same time, P 300 was tested in 36 healthy children as control. Results In the children with ADHD, the P 300 latency was longer and amplitude was lower than those in the healthy children before comprehensive intervention (P
4.Effects of static tensile strain on the production of prostaglandin E_2 by hum an periodontal ligament fibroblast
Jun HU ; Xiangming ZHENG ; Xinming CHEN
Journal of Practical Stomatology 2000;0(06):-
Objective: To study the effects of static tensile strai n on the secretion of prostaglandin E 2 (PGE 2) of human periodontal ligament fibroblasts (PLFs). Methods: Human PLFs were treated by tensile strain values of 0%,8%,12%,16% and 20% for 24, 48 and 72 h respecti vely with a self-devised loading apparatus in vitro. All samples were rando mly allocated into 15 groups and there were 3 in each group. After treatment cu lture media of the samples were collected and the content of PGE 2 in each medi um sample was determined using RIA ELISA. The data analysis was carried out with SPSS using Dunnett test. Results: In group of 0% the sec retion of PGE 2 by PLFs per day had no relation with loading time; E 2 secre tion increased with the increace of loading time and with the tensile strain va lue in the group of 8%,12% and 16%(P
5.Effects of Early Intervention on Functional Outcome and NGF in Brain of Rats with Brain Damage
Jun HU ; Qiujun LIN ; Yanhui CHEN
Chinese Mental Health Journal 2002;0(07):-
Objective: To explore the effects of early intervention on functional outcome and the repair mechanisms in rats with hypoxic-ischemic brain damage (HIBD). Methods: A HIBD rat model was established by ligating either uterine vessel of one pregnant horn. The way of intervention was the neonatal handling and enriched environment. One trial passive avoidance response, brainstem auditory evoked potential (BAEP) and NGF levels in the brain were used as assessment index. Results:(1) In the one trial passive avoidance response test, the medial step-through latency (STL) of intervention group (n=18) was much longer than that of non-intervention group (n=15) (P
6.Comparative Study on the Main Medical Component Contents of Angelica pubescens in Famous Region Chongqing and Other Domestic Areas in China
Taide HU ; Shaocheng CHEN ; Jun TAN
China Pharmacy 2015;26(33):4711-4713
OBJECTIVE:To compare the contents of osthole and columbianadin in Argelica. pubescens in Wushan county, Wuxi county in Chongqing and other domestic areas in china. METHODS:HPLC was performed on the column of Shiseido Cap-cell Pak C18 with mobile phase of acetonitrile-water(gradient elution) at flow rate of 1.0 ml/min,detection wavelength was 330 nm,column temperature was 30 ℃ and volume injection was 10 μl. RESULTS:The linear range was 0.015 1-0.301 6 mg/ml(r=0.999 9) for osthole and 0.016 7-0.334 4 mg/ml(r=0.999 9) for columbianadin;RSDs of precision,stability and reproducibility tests were lower than 2.0%;recoveries were 98.46%-106.11%(RSD=2.34%,n=9)and 98.24%-102.69%(RSD=1.29%,n=9), respectively. CONCLUSIONS:The method is simple and good reproducibility,and and can be used for the contents determination of osthole and columbianadin in A. pubescens. The contents of osthole and columbianadin in A. pubescens of Wushan county in Chongqing are obviously higher than Wuxi county and other domestic areas in China.
7.Totally extraperitoneal laparoscopic hernioplasty:A report of 16 cases
Cunchuan WANG ; Jun CHEN ; Youzhu HU
Chinese Journal of Minimally Invasive Surgery 2001;0(06):-
Objective To study the technique of totally extraperitoneal laparoscopic hernioplasty(TEP). Methods 16 patients with inguinal hernia were treated with TEP.There were 14 indirect inguinal hernia and 2 direct inguinal hernia.All patients were treated by laperoscopic herhisplasty through extraperitoneal route. Results All cases were operated on successfully.Operation time was 65.5(40~120)min.The average postoperative hospital stay was 3.7(3~7)days.No complication occurred.There was no recurrence. Conclusionss TEP is a satisfactory technique with a low recurrence rate and a low major complication rate.
8.Application of three-dimensional magnetic resonance imaging and DSA in the diagnosis of cerebral venous sinus thrombosis
Jun HU ; Shugui SHI ; Kangning CHEN
Chinese Journal of Cerebrovascular Diseases 2014;(4):188-191
Objective To investigate the diagnostic value of three-dimensional magnetic resonance imaging (MRV ) and digital subtraction arteriography (DSA ) in cerebral venous sinus thrombosis (CVST). Methods Twenty-nine patients with CVST admitted to the First Affiliated Hospital of the Third Military Medical University (Southwest Hospital)from January 2008 to February 2014 were enrolled retrospectively. Eleven of them were males and 18 were females. Their course of disease ranged from 3 days to 3 months. Nine patients were in the acute phase (<1 week),12 were in the subacute phase (1-2 weeks),and 8 were in the chronic phase (>2 weeks). All the patients were underwent magnetic resonance (MR)(T1 or T2 weighted image ),three-dimensional MRV,and DSA examinations. Results DSA detected 29 and MRV detected 24 patients. MRI revealed 12 patients had cerebral infarction and 7 had cerebral infarct and hemorrhage. On T2-weighted sequences,16 patients showed the flow void effect of venous sinus disappeared,and thromboses with different signals in the sinuses. MRV showed part development of the veins in 14 cases and no development in 10 cases,including 4 with collateral circulation. Compared with DSA,the positive detection rate of MRV was 82. 8%. The lesion sites of 3 patients involving the transverse sinus and 2 involving the sagittal sinus were not detected on MRV. Conclusion Compared with DSA,the MRV has a certain percentage of missed diagnosis rate for CVST. In clinical work,if MRV diagnosis is negative,it can not exclude the diagnosis of CVST,and further DSA examination is needed.
9.Clinical significance of plasma D-dimer, fibrinogen and fibrin/fibrinogen degradation product detection in patients with chronic obstructive pulmonary disease
Jun CHEN ; Bicheng HU ; Tianpen CUI
Chinese Journal of Postgraduates of Medicine 2014;37(25):5-6
Objective To investigate clinical significance of plasma D-dimer (D-D),fibrinogen (FIB) and fibrin/fibrinogen degradation product (FDP) in patients with chronic obstructive pulmonary disease (COPD).Methods The level of plasma D-D,FIB and FDP in 150 patients with COPD and 80 healthy persons were detected,and compared.Results The level of plasma D-D,FIB and FDP in COPD patients were significantly higher than those in healthy persons[(2.16 ± 0.61) mg/L vs.(0.55 ± 0.04) mg/L,(5.88 ± 1.52) g/L vs.(3.12 ± 0.35) g/L,(7.18 ± 1.63) mg/L vs.(3.62 ± 1.55) mg/L],there were significant differences (P < 0.01).Conclusion Monitoring the level of plasma D-D,FIB and FDP in COPD patients can provide reliable basis in hypercoagulable state and primary and secondary hyperfibrinolysis.
10.Expression of Human Telomerase Reverse Transcriptase in Nasopharyngeal Carcinoma and its Clinical Significance
Jun HU ; Baoan LIU ; Senlin CHEN
Journal of Chinese Physician 2001;0(04):-
Objective This study was designed to investigate the expression of human telmerase reverse transcriptase (HTERT) in nasopharyngeal carcinoma (NPC) and its clinical significance.Methods Expression of HTERT in NPC and dysplasia of nasopharyngeal epithelium and chronic inflammation of nasopharyngeal epithelium were determined by immunocytochemical staining.The results were analysed,compared with the clinical TNM stage ,lymph node metastasis ,other places metastasis and prognostic survivals of the NPC patients.Results Positive rate of HTERT in NPC was 83 7%(70/84),while positive rate of HTERT in dysplasia of nasopharyngeal epithelium and chronic inflammation of nasopharyngeal epithelium both were 0 0%(0/8 and 0/16) (P0 05).The median survival of HTERT positive group was shorter than the nagative one.Conclusions Expression of HTERT may be a potential marker for clinical diagnosis of NPC and may has significance in predicting clinical TNM stage, metastasis and prognostic survival of the NPC patients.