Acquired Immunodeficiency Syndrome ; diagnosis ; diagnostic imaging ; China ; Humans ; Radiography ; Radiology ; methods

Objective To investigate the effects of rocuronium on the neuromuscular junction of rat diaphragm. Methods One hundred and sixty rats were used in the study which was approved by the Animal Care Committee of the General Hospital of PLA. In isolated non-uniformly stretched muscle preparation (INSMP) of rat diaphragm, micro-endplate potentials (MEPP) and endplate potentials (EPP) were recorded simultaneously with one microelectrode of one endplate. The effects of rocuronium in dosages of 2.5, 5, 10, 20?g/ml on the amplitude and frequency of MEPP and the amplitude of EPP were observed. Results Rocuronium could decrease both the amplitude and frequency of MEPP obviously and the onset time was 1min after drug administration. The amplitude of EPP was depressed by rocuronium in a dose of 5?g/ml at 3min. Neither 2.5?g/ml nor 0.5?g/ml of rocuronium produced any effect on the amplitude of EPP. Conclusion The results indicated that rocuronium might produce a rapid and early presynaptic effect on neuromuscular junction in INSMP in rats.

With the progress of society and development of sexual medicine, the therapeutic effects of female sexual dysfunction (FSD) have been improved increasingly. This review summarizes the basic therapeutic approaches to FSD, including psychotherapy, sexual behavior therapy, mechanical skills, life style adjustment, physical exercise, acupuncture, medication, surgery, and gene therapy. It also points out the objective understanding of the limitations of the available therapeutic methods, with stress on patient-oriented comprehensive therapeutic principles and increased attention to recognition education among the patients so as to improve the present status of FSD treatment.
Female ; Humans ; Sexual Dysfunction, Physiological ; therapy

Objective: To evaluate the efficacy and safety for the application of low-dose vitamin K antagonist (VKA) during whole pregnancy and low-molecular-weight heparin/heparin at early pregnancy in patients after mechanical heart valve replacement. Methods: We searched the Cochrane library (2016 Issue 2), PubMed, EMbase, CBM, Tsinghua Tongfang (CNKI), Wanfang and VIP databases to collect the literatures for the application of low-dose VKA during whole pregnancy and low-molecular-weight heparin/heparin at early pregnancy up to 2016-06. The literatures were independently screened by 2 reviewers and Meta-analysis was performed using RevMan 5.3 software. Results: 12 studies were finally enrolled. Meta-analysis presented that compared with the application of low-molecular-weight heparin/heparin at early pregnancy, low-dose VKA during whole pregnancy showed decreased valvular thrombosis rate (OR=0.26, 95% CI 0.13-0.54, P<0.001), lower spontaneous abortion rate (OR=1.99, 95% CI 1.21-3.26, P=0.006) and increased fetal abnormality rate (OR=3.39, 95% CI 1.11-10.37, P=0.03); while the maternal mortality (OR=0.79, 95% CI 0.24-2.58, P=0.70), peri-natal bleeding rate (OR=0.56, 95% CI 0.27-1.18, P=0.13) and the incidence of stillbirth (OR=1.80, 95% CI 0.94-3.44, P=0.07) were similar between two conditions. Conclusion: Current evidence indicated that the application of low-doseVKA during whole pregnancy decreased the rates of valvular thrombosis and spontaneous abortion in patients after mechanical heart valve replacement, while increased the rate of fetal abnormality. Further investigation is needed to confirm the above conclusion.

By direct communication between clinicians and laboratorians, obstacles between clinical work and laboratory diagnosis were unequivocally found at an academic conference. Many clinical physicians feel disappointed and frustrated at the laboratory diagnosis by semen analysis and frankly express their expectations, as to recognize the role and significance of laboratory diagnosis, understand the value of routine semen analysis, work out the puzzles in the analysis of sperm morphology, fulfil the requirements for the identification of cells in semen, and obtain responses from and initiate discussions among laboratorians about the relevant questions. Both laboratorians and clinicians are appealing for strengthened management and earlier establishment of national standards and operating specifications for laboratory diagnosis by semen analysis.
Clinical Laboratory Techniques ; Communication ; Humans ; Interprofessional Relations ; Male ; Physicians ; Semen ; Semen Analysis

Objective: To discuss the safety issues of moxibustion therapy in view of moxibustion materials. Methods: The analyses and assessment were performed based on the survey carried out on the use of moxa, modem and ancient records, modern studies, and clinical applications. Results:Moxa has been used as both a medicine and a food for a long history in China. Regarding moxibustion specifically, moxa has been proven to be the optimum choice for moxibustion therapy,through practices and experiments by doctors from different generations. No records have shown any side- or adverse-effects of moxa applied in moxibustion therapy. Conclusion: Moxa has been used in multiple ways for several thousands of years by Chinese people. As the main material for moxibustion therapy, its safety has been proven by documents and clinical practices.

Adolescent ; Adult ; Aged ; Diagnosis, Differential ; Ependymoma ; pathology ; Female ; Follow-Up Studies ; Humans ; Immunohistochemistry ; Magnetic Resonance Imaging ; Male ; Meningeal Neoplasms ; diagnostic imaging ; metabolism ; pathology ; surgery ; Meningioma ; diagnostic imaging ; metabolism ; pathology ; surgery ; Mucin-1 ; metabolism ; Oligodendroglioma ; pathology ; Tomography, X-Ray Computed ; Vimentin ; metabolism ; Young Adult

Animals ; Danazol ; pharmacology ; Endometriosis ; drug therapy ; Endometrium ; drug effects ; Female ; Interleukin-6 ; metabolism ; RNA, Messenger ; genetics ; Rats ; Rats, Sprague-Dawley

Cerebral Hemorrhage ; etiology ; Cerebrospinal Fluid Rhinorrhea ; surgery ; Humans ; Male ; Middle Aged ; Postoperative Hemorrhage

Adolescent ; Adult ; Female ; Histiocytic Necrotizing Lymphadenitis ; diagnosis ; therapy ; Humans ; Lymph Nodes ; Male ; Middle Aged ; Neck ; Young Adult