1.Present status and application of orthopedics virtual surgery system
Yaojun DAI ; Jun CAO ; Fei HE
Chinese Journal of Tissue Engineering Research 2007;0(30):-
Orthopedics virtual surgery system is a rapidly developing domain in recent years,and has exhibited a promising application.Currently,softwares about orthopedics virtual surgery system have already been applied in medical clinic and education.This paper reviewed present situation of this system,introduced some key technology such as medical image segmentation,registration and fusion,3D visualization and 3D interactive,and discussed main application such as orthopedics virtual surgery,surgical protocol,assisting clinical diagnosis,real-time chiri-cal consmlfation,assisting medical education,training and examination,rehabilitation care,prosthetic device,or guidance in surgery.In addition,the development trend of this system is predicted.With development of orthopedics virtual surgery system,the time of surgery will be consumedly economized and the risk of surgery will be reduced,greatly benefiting orthopedics.
2.Biomechanical stability of transpedicular screw fixation in lower cervical spine
Jun CAO ; Yaojun DAI ; Fei HE
Chinese Journal of Tissue Engineering Research 2007;0(44):-
Transpedicular screw fixation for cervical spine is the strongest spinal posterior fixation that could provide tri-column biomechanical stability,and it has been gradually identified as a quite high value in clinical application.The pedicle of vertebral arch is adjacent to vital neurovascular structures;thereby pedicle screw fixation in the cervical spine has been considered as a potential risk of injury and been limited in clinics.This study aims to review the studies on the current situation and progress of pedicle screw fixation techniques in lower cervical disease by investigating cervical pedicle morphology,biomechanical property,transpedicular screw insertion techniques and internal fixation system,computer assisted image-guided navigation,the indication,contraindication and complications of pedicle screw fixation.The article shows that preoperative careful evaluation for the morphology of the lower cervical pedicles,using kinds of new image guided techniques and meticulous techniques of screw placement in operation are essential in reducing operational risk and offering widely application.
3.Effects of xinshuai mistura on plasma angiotensin II, atrial natriuretic peptide and N terminal pro-brain natriuretic peptide in patients with heart failure.
Mei DAI ; Qing-xiang WEN ; Jun-ren HE
Chinese Journal of Integrated Traditional and Western Medicine 2006;26(10):888-891
OBJECTIVETo observe the effects of Xinshuai Mistura (XM) on plasma angiotensin II (Ang II), atrial natriuretic peptide (ANP) and N terminal pro- brain natriuretic peptide (Nt-proBNP) in patients with heart failure (HF).
METHODSFifty-nine patients with HF (NYHA class II-IV) were randomly divided into two groups, the treated group treated with XM and the control group with Wuling Pulvis (WP), both on the base of captopril treatment. The treatment course was two weeks. Plasma levels of Ang II , ANP and Nt-proBNP were observed.
RESULTSThe plasma levels of Ang I, ANP and Nt-proBNP showed an ascending tendency along with the increasing in severity of HF(P < 0.01), and significantly decreased after treatment in the treated group (P < 0.01), but with no remarkable difference as compared with those in the control group (P > 0.05).
CONCLUSIONXM had definite therapeutic effects on excessive neuroendocrine activation in HF patients.
Adult ; Aged ; Angiotensin II ; blood ; Angiotensin-Converting Enzyme Inhibitors ; therapeutic use ; Atrial Natriuretic Factor ; blood ; Captopril ; therapeutic use ; Drug Therapy, Combination ; Drugs, Chinese Herbal ; therapeutic use ; Female ; Heart Failure ; blood ; drug therapy ; Humans ; Male ; Middle Aged ; Natriuretic Peptide, Brain ; blood ; Peptide Fragments ; blood ; Phytotherapy ; Single-Blind Method ; Treatment Outcome
4.Application of c-- reactive protein in diagnosis and treatment of nosocomial pneumonia with coal workers' pneumoconiosis.
Jun-he DAI ; Pei-yue LIU ; Ling-wen KONG
Chinese Journal of Industrial Hygiene and Occupational Diseases 2005;23(5):325-325
Aged
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Aged, 80 and over
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Anthracosis
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blood
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C-Reactive Protein
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analysis
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metabolism
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Cross Infection
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diagnosis
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therapy
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Humans
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Male
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Middle Aged
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Pneumonia
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blood
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Serum
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chemistry
5.Study of regulation of miR-21 on ADAMTS-1 expression
Hong ZHAO ; Pingbo YAO ; Li DAI ; Ping ZHONG ; Jun HE
The Journal of Practical Medicine 2015;31(15):2426-2429
Objective To investigate the regulatory effect of miR-21 on ADAMTS-1 expression in pulmonary fibrosis model. Methods A mouse model of pulmonary fibrosis was established using bleomycin (BLM) anda model of pulmonary fibrosis was constructed in vitro , the expression level of miR-21 was measured by quantitative real-time polymerase chain reaction (qRT-PCR), while the protein expression of ADAMTS-1 was measured by Western blot. NIH3T3 were transfected with miR-21 mimics and inhibitor in vitro and the cellular expression of ADAMTS-1 was measured by Western blot. Results Compared with the blank group , in mouse models of pulmonary fibrosis , the miR-21 expressions in lung tissues at three time points after BLM-treatment were significantly up-regulated while an evident decrease in ADAMTS-1 expressions were observed (P < 0.01). In vitro pulmonary fibrosis model , NIH3T3 cells after TGF-β1 in concentration 5 μg/L stimulation down-regulated ADAMTS-1 expression and up-regulated miR-21 expression (P < 0.01). NIH3T3 transfected with miR-21 mimics and inhibitor, up-regulated miR-21 expression, while down-regulated ADAMTS-1 protein expression. Conclusions Up-regulation of miR-21 and Down-regulation of ADAMTS-1 might be involved in the progression of pulmonary fibrosis model; miR-21 could negatively regulate ADAMTS-1 expression.
6.Antibacterial components from artificially induced dragon's blood of Dracaena cambodiana.
He-mei JIANG ; Hui WANG ; Jun WANG ; Hao-fu DAI ; Yan-ping LUO ; Wen-li MEI
China Journal of Chinese Materia Medica 2015;40(20):4002-4006
Ten compounds were isolated from the artificially induced dragon's blood of Dracaena cambodiana by various column chromatographies on silica and sephadex LH-20 gel. Based on spectral analysis of NMR and MS, their structures were identified as 3, 4-dihydroxyallylbenzene (1), 3', 4', 5'-trimethoxycinnamylalcohol (2), pinoresinol (3), (2R)-7, 4'-dihydroxy-8-methylflavane (4), (2R)-7,4'-dihydroxy-5-methoxy-8-methylflavane(5),(2S)-7,3'-dihydroxy-4'-methoxy-8-methylflavane(6) ,(2S)-4',7-dihydroxy-6, 8-dimethylflavane(7), 4,2',4'-trihydroxychalcone(8), 4,4'-dihydroxy-2-methoxydihydrochalcon(9) and Cambodianin E (10). Antibacterial activity assay showed that compounds 1, 4 and 10 have inhibitory effect on Fusarium oxysporum f. sp. cuben, Fusarium oxysporum f. sp. niveum, Fusarium oxysporum f. sp. vasinfectum and Ralstonia solanacearum.
Antifungal Agents
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chemistry
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isolation & purification
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pharmacology
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Dracaena
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chemistry
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Drugs, Chinese Herbal
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chemistry
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isolation & purification
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pharmacology
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Fusarium
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drug effects
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Molecular Structure
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Plant Extracts
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chemistry
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isolation & purification
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pharmacology
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Spectrometry, Mass, Electrospray Ionization
7.Investigation on deciduous dental caries among preschool children in Chongqing city.
Lin JIANG ; Qingming ZHUANG ; Jinhua WANG ; Jun DENG ; Hechuan ZHAO ; Songlin HE ; Lina DAI
West China Journal of Stomatology 2014;32(5):472-475
OBJECTIVETo investigate the status of deciduous dental caries among preschool children in Chongqing city and to compare the oral health status of preschoolers from public and private kindergarten.
METHODSAccording to the criteria recommended by The Third National Oral Health Investigation, the deciduous caries of 5 030 preschool children aged 3 to 6 years old from 40 private kindergartens and 16 public kindergartens in Yuzhong district of Chongqing were examined. The prevalence of dental caries and the mean dmft and filling rate were calculated. The results were analyzed using SPSS 21.0 software package.
RESULTSMaxillary deciduous central incisors and mandibular deciduous molar were most prone to decay in 5,030 children. The prevalence of dental caries was 54.08% (2,720/5,030). The mean dmft score was 2.58 and the filling rate was 0.98% (127/12,993). The prevalence of dental caries and mean dmft increased gradually as the children were growing up (P < 0.05). The rate of filling teeth of the 6 year old group was higher than other groups (P < 0.05). No significant difference between males and females were noted (P > 0.05). The prevalence rate of deciduous dental caries among private kindergartens was 61.04% (1,656/2,713), with a mean dmft of 3.12 and filling rate of 0.35% (30/8,465). The prevalence rate of deciduous dental caries among public kindergartens was 45.92% (1,064/2,317), with a mean dmft of 1.95 and filling rate of 2.14% (97/4,528). Statistical analysis revealed significant differences in the prevalence rate, mean dmft, and filling rate between two kinds of kindergarten (P < 0.05).
CONCLUSIONDeciduous dental caries of preschool children is an important problem in Chongqing city and the children from private kindergarten had very low filling rate.
Child ; Child, Preschool ; China ; DMF Index ; Dental Caries ; Dental Pulp Cavity ; Female ; Humans ; Incisor ; Male ; Molar ; Oral Health ; Prevalence ; Tooth, Deciduous
8.Value of urinary retinal binding protein in early renal function impairment for patients with pneumoconiosis complicated with chronic obstructive pulmonary diseases.
Jun-he DAI ; Si-hai LIU ; Xiao-jing LIU ; Li-da YAN ; Wen-shou XU
Chinese Journal of Industrial Hygiene and Occupational Diseases 2006;24(2):123-124
9.Clinicopathologic observation of renal carcinoid tumors.
Po LI ; Chang HE ; Song-song HUANG ; Li BO ; Lu-jun DAI
Chinese Journal of Pathology 2012;41(12):846-847
CD56 Antigen
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metabolism
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Carcinoid Tumor
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diagnostic imaging
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metabolism
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pathology
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surgery
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ultrastructure
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Chromogranin A
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metabolism
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Follow-Up Studies
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Humans
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Kidney Neoplasms
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diagnostic imaging
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metabolism
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pathology
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surgery
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ultrastructure
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Male
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Microscopy, Electron, Transmission
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Middle Aged
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Phosphopyruvate Hydratase
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metabolism
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Synaptophysin
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metabolism
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Tomography, X-Ray Computed
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Vimentin
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metabolism
10.Clinical analysis of Staphylococcus aureus resistance to methicillin in patients with coal worker's pneumoconiosis complicated by lung cancer.
Si-hai LIU ; Pei-yue LIU ; Wen FENG ; Jun-he DAI ; Cheng-dong QI ; Fang QIAN
Chinese Journal of Industrial Hygiene and Occupational Diseases 2004;22(5):391-392