2.Treatment of recurrent cavernous hemangiomas by ethanol thrombosis and pinyangmycin sclerothery
Fengshan GAO ; Jiying DONG ; Jun DU
Chinese Journal of Medical Aesthetics and Cosmetology 2001;0(06):-
Objective To investigate a safe, effective and mini-invasive method in the treatment of recurrent cavernous hemangiomas. Methods Under local or ketamine anesthesia, ethanol was injected into hemangioma to embolize the draining vessels, and 8~16 mg pinyangmycin was then injected into the lesion slowly. After 7~10 days, second injection of pinyangmycin and total 3~5 times were needed as a course of treatment. Results In the 6 cases reported, shrinkage and degradation were observed and finally tumor was disappeared. There was no skin necrosis, no recurrence and other complications in the 1~5 years follow-up period. Conclusion Ethanol embolization and pinyangmycin injection is a safe, simple, mini-invasive, and effective method in treating the recurrent cavernous hemangiomas.
3.T cell/histiocyte-rich large B cell lymphoma.
Dong-ge LIU ; Jun DU ; Qi YU
Chinese Journal of Pathology 2005;34(6):377-378
Aged
;
Antigens, CD
;
metabolism
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Antigens, CD20
;
metabolism
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Antigens, Differentiation, Myelomonocytic
;
metabolism
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CD3 Complex
;
metabolism
;
CD79 Antigens
;
metabolism
;
Diagnosis, Differential
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Histiocytes
;
immunology
;
pathology
;
Hodgkin Disease
;
immunology
;
pathology
;
Humans
;
Leukocyte Common Antigens
;
metabolism
;
Lymphoma, B-Cell
;
immunology
;
pathology
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Lymphoma, Large B-Cell, Diffuse
;
immunology
;
pathology
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Male
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T-Lymphocytes
;
immunology
;
pathology
4.Detection of serum antibodies against flagellin with a protein biochip in patients with Lyme borre-liosis
Wei-Dong DU ; Su-Min HE ; Xue-Jun ZHANG ;
Chinese Journal of Dermatology 2003;0(11):-
ObjeCtive To investigate the value of protein biochip in the diagnosis of Lyme borreliosis. Methods The serum IgM and IgG antibodies against flagellin were detected by flagellin coated-and N-hydroxysuccinimide (NHS) modified-biochips in 82 patients with neuroborreliosis (NB),35 patients with erythema migrans (EM) and 44 normal controls.The results were compared with those from enzyme-linked immunosorbent assays (ELISA) and Western blot.Results The levels of both IgM and IgG antibodies were significantly higher in the NB patients than those in the normal controls (P
5.Expression and relationship between matrix metalloproteinase-7 and E-cadherin in gastric cancer
Rongkun DONG ; Du ZHANG ; Jianpeng HUANG ; Mingfu HAN ; Qibin WANG ; Jun FU ; Lin WANG
Cancer Research and Clinic 2011;23(1):25-27
Objective To evaluate the expressions of MMP-7, E-cadherin in gastric carcinoma, and their relationship with tumor cell invasion and metastasis. Methods The MMP-7 mRNA and E-CD mRNA were detected by hybridization in situ in 78 gastric cancer tissues. Then analyze the relationship between the expression of MMP-7, E-CD and clinicopathological features. Results The expressions of MMP-7 and Ecadherin were significantly related with the invasion and metastasis of gastric cancer cell. The E-CD mRNA expression rate in MMP-7 mRNA positive gastric carcinoma tissue was much lower than that in negative carcinoma tissue (9.09 % vs 66.70 %). Conclusion Expression of MMP-7 mRNA and E-CD mRNA is associated with invasion, metastasis. Detection of MMP-7 mRNA and E-CD mRNA in bioptic specimens may be helpful in predicting tumor metastatic and recurrent potential and prognosis for patients with gastric carcinoma.
6.AFLP fingerprinting of Pinellia ternata and its application.
Juan DU ; Xiao-jun MA ; Xue-dong LI
China Journal of Chinese Materia Medica 2006;31(1):30-33
OBJECTIVETo obtain more information on DNA fingerprintings and to confirm the genetic relationships of ten wide populations of Pinellia tornata.
METHODCollect wide-type or cultivated P. tornata from ten major production areas nation-wide as material. Twelve combinations of EcoR I and Mse I primers were used to asses divergence among ten populations. The data were analyzed using unweighted pair-group method, based on arithmetic averages (UPGMA) bootstrap analysis. Cluster analyses were performed by using NTSYSpc software version 2.1. The alkaloid was extracted from P. ternate with chlorolform and determined in UV absorption spectroscop.
RESULT1,673 bands were applied with 12 combinations. These results of cluster were congruent with differences in total alkloids.
CONCLUSIONThe results of the study showed a potential application of AFLP fingerprinting for identification of P. ternata.
Alkaloids ; analysis ; China ; Cluster Analysis ; DNA Fingerprinting ; DNA, Plant ; genetics ; Phylogeny ; Pinellia ; chemistry ; genetics ; Plants, Medicinal ; chemistry ; genetics ; Quality Control
7.Simultaneous liver-pancreas-duodenum transplantation with the pancreas of the recipients reserved (three cases report)
Lai WEI ; Dong CHEN ; Dunfeng DU ; Jipin JIANG ; Jun YANG ; Zhixin CAO ; Zhishui CHEN
Chinese Journal of Organ Transplantation 2014;35(11):650-653
Objective To investigate the effects of treatment on end-stage liver disease and diabetes mellitus by simultaneous liver-pancreas-duodenum transplantation with the pancreas of the recipients reserved.Method Simultaneous liver-pancreas-duodenum transplantations were carried out in three patients with the pancreas of the recipients reserved.The diseases of the recipient 1,2,and 3 were alcoholic liver cirrhosis and diabetes mellitus,chronic hepatitis B liver cirrhosis and diabetes mellitus,and chronic hepatitis B liver cirrhosis and diabetes mellitus complicated with renal function failure.The recipient 3 received simultaneous renal transplantation.Result The recipient 1 suffered from pancreatitis after the operation and discharged with normal liver function and blood glucose levels,and he was treated with insulin at 4th year after the operation.Intestinal fistula occurred in the recipient 2 and drainage was done without acute peritonitis,the liver allograft was experienced an acute rejection episode treated by intravenous bolus methylpredisolone at 19th month after operation,but gastrointestinal perforation happened and the patient died of acute peritonitis.In the recipient 3,peripancreatic effusion and pancreatitis happened and were treated by drainage,and the recipient survived to now with normal liver and kidney functions,but given insulin at first year after operation.Conclusion It is effective to implement simultaneous liver-pancreas-duodenum transplantation with the pancreas of the recipients reserved on the patients with end-stage liver disease and diabetes mellitus.However,how to maintain the pancreatic endocrine function after the transplantation for a long period awaits further investigation.
8.The MR features of granulomatous mastitis
Min CHEN ; Weiying DONG ; Lingjing GU ; Zhongli DU ; Yutao LIU ; Yanping WANG ; Jun MAO
Journal of Practical Radiology 2014;(5):774-777
Objective To explore the MR features of granulomatous mastitis and to improve the diagnosis of the disease.Methods MR findings of 1 1 patients with granulomatous mastitis confirmed by pathology were retrospectively reviewed.Results Nine (81.82%)lesions showed regional or diffused hyperintensity on T2 WI with heterogeneous gridding features.2 (18.18%)lesions showed mass-like enhancement and 9 lesions showed non-mass-like enhancement.Of 9 (81.82%)lesions with non-mass-like en-hancement,the enhancement patterns included diffused in 2 (18.18%)cases,regional in 4 (36.36%)cases,multiple-regional in 2 (18.18%)cases,and focal in 1 (9.09%)case,respectively.All the lesions showed early heterogeneous enhancement,and clumped-ring enhancement was seen in 6 lesions.The signal intensity of the lesions was increased and more uniform in the later stage.The time-signal intensity curve was type I in 7(63.64%)cases,type II in 3 (27.27%)cases and type III in 1 (9.09%)case.The mean ADC value was (1.82±0.1 7)×10 -3 mm2/s,and there was no significant difference between lesions and normal regions (t=1.766, P >0.05).Concomitant signs included barymastia,thickening of skin,edema surrounding the lesions,and axillary lymph node en-largement.The BI-RADS category was 3 degree in 1 (9.09%)case,4a degree in 5 (45.45%)cases,4b degree in 2 (18.18%)ca-ses,4c degree in 2 (18.18%)cases and 5 degree in 1 (9.09%)case.The misdiagnosis ratio was 54.55%.Conclusion Granuloma-tous mastitis has certain characteristic MR features.The misdiagnosis ratio of granulomatous mastitis is high.Therefore,clinical data should be referred when making diagnosis.
9.Complement activation in acute coronary syndromes
Suhua WU ; Hong MA ; Yugang DONG ; Jiangui HE ; Xinxue LIAO ; Jun LIU ; Wutao ZENG ; Zhimin DU
Chinese Journal of Pathophysiology 1999;0(09):-
AIM:To evaluate complement activation in patients with all forms of acute coronary syndromes(ACS)and to examine the relationship between the degree of complement activation and myocardial injury.METHODS:The subjects were divided into 2 groups:110 ACS patients(group ACS)and 18 healthy persons(group control).One hundred and ten patients with ACS were divided into 3 sub-group:51 patients with ST-segment elevated myocardial infarction(STEMI),28 patients with non-ST-segment elevated myocardial infarction(NSTEMI)and 31 patients with unstable angina(UA).Complement 3(C3),complement 4(C4),troponin T(TnT)as well as creatine kinase MB(CK-MB)were evaluated.RESULTS:Plasma C3 and C4 peak levels were significantly higher in patients with STEMI [(1 525?302)mg/L and(423?123)mg/L] and NSTEMI [(1 516?289)mg/L and(396?68)mg/L] than those in patients with UA [(1 275?172)mg/L and(356?91)mg/L] and the control subjects [(1 072?196)mg/L and(182?73)mg/L](P
10.Effects on lymphocyte & T subcytes of SARS patients treated by integrative traditional Chinese and western medicine
Jun LI ; Shaodan LI ; Jingchao LIU ; Ning DU ; Yi DONG ; Fusheng WANG ; Yongping YANG ; Xiaohe XIAO
Chinese Journal of Immunology 1985;0(05):-
Objective:To study the effects on lymphocyte & T subset of SARS patients treated by integrative traditional Chinese and western medicine(ICWM). Methods:48 patients were randomly divided into two groups, the control group treated by western medicine (WM) alone and the test group treated by ICWM. The test group patients took the traditional Chinese medicine by 3 weeks based on their conditions. Lymphocyte and T subset were measured. Results:① At pretreatment, absolute value of lymphocyte of 38 patients in all patients were low. There were 19 patients with lowered CD3 +, and 28 patients with lowered CD4 +/CD8 + ratio in 38 patients with T subset measured. ② The value of lymphocyte in plasma in patients after ICWM treatment increased from 1 00?10 9?0 46?10 9 L -1 to 1 92?10 9?0 74?10 9 L -1 ( P