We are reporting a case of molluscum contagiosum in a 3-year-old boy who showed a good response to diphenylcyclopropenone (DPCP) immunotherapy. The lesions were multiple, 2 to 7mm in size, centrally umbilicated, normal skin-colored papules of 7 months' duration which were distributed on the penoscrotal area, extremities and trunk. In spite of several treatments using extraction and curettage, new lesions developed continuously. The patient was sensitized with 0.1ml of 1% DPCP solution in acetone on his right shoulder and there-after challenged with solution of varying concentrations (0.05 to 0.1%) on his left shoulder once or twice a week to maintain a mild eczema. Clinical improvement was noted 1 week after sensitization and almost all of the lesions cleared after 8 week's treatment.
Acetone ; Child, Preschool ; Curettage ; Eczema ; Extremities ; Humans ; Immunotherapy* ; Male ; Molluscum Contagiosum* ; Shoulder

No abstract available.
Animals ; Antibody Formation* ; Cattle ; Enzootic Bovine Leukosis* ; Giant Cells* ; Goats* ; Leukemia Virus, Bovine*

Color developers(CD) have been noted to produce lichen planus like eruption as well as eczematous contact dermatitis. The chemicals involved are derivatives of paraphenylenediamine or aniline, i. e., Kodak CD 2, Kodak CD 3, Agfa TSS. We report a 28-year-old male who showed a feature of lichenoid contact dermatitis after exposure to color developer. Patch test revealed positive reactions to CD2, CD3 and CD4. Skin biopsy from a patch site showed lichen planus-like tissue reaction.
Adult ; Biopsy ; Dermatitis ; Dermatitis, Contact* ; Humans ; Lichen Planus ; Lichens ; Male ; Patch Tests ; Skin

To determine the value of ultrasonography for the diagnosis of testicular rapture due to blunt trauma, we reviewed 69 patients of blunt scrotal trauma, which were evaluated by ultrasound before treatment. Thirty patients were managed conservatively, of which 3 cases were explored lately due to persistent pain or mass, and 39 explored immediately. Of the 30 patients treated conservatively the injury was resolved in 27. Surgical exploration of the 42 cases revealed testicular rupture in 29 and simple hematocele in 13. Analysis of the 29 cases with testicular rupture demonstrated that orchiectomy rates were 20% in early exploration and 53% in delayed exploration. in the 27 cases the testicular rupture was correctly diagnosed by ultrasonography, and there were 4 false-positive and 2 false-negative diagnoses of rupture. The specificity and sensitivity for the diagnosis of testicular rupture are 70% and 93%, and the positive and negative predictive values are 87% and 82%, respectively. Ultrasonography used in conjunction with a thorough physical examination is highly sensitive in identifying testicular rupture, and can provide objective information supporting the need for early surgical exploration in patients with blunt scrotal trauma.
Diagnosis ; Hematocele ; Humans ; Male ; Orchiectomy ; Physical Examination ; Rupture* ; Sensitivity and Specificity ; Ultrasonography*

We report herein a case of desmoplastic trichoepithelioma in a 73-year-old female, who is the oldest among the patients of the disease reported in Korea. She had an asymptomatic, hard, annular lesion, measuring 0.6 x 0.7 cm with an elevated border and a depressed center on the left nasolsbial fold. Histopathological findings showed narrow strands of basaloid tumor cells, horn cysts and a desmoplastic stroma.
Aged ; Animals ; Female ; Horns ; Humans ; Korea

Epithelial to mesenchymal transition (EMT) is an important etiologic factor for the development of peritoneal fibrosis in CAPD patients. Mesothelial cells are main source of trans-differentiated fibroblasts under stress from the bioincompatible peritoneal dialysate. In our study there was no difference in dialysate TGF-beta and VEGF between the low and high GDP groups during an initial 12 months. However, after adjusting with D-CA125, the low GDPs group showed a significantly lower D-TGF-beta/D-CA125 and D-VEGF/CA125 during the initial 12 months. Among the adjusted peritoneal growth factors for CA125, VEGF/CA125 and TGF-b/CA125 were factors significantly associated with greater EMT in this study. Adjustment of the peritoneal growth factor for effluent CA125 (surrogate for mass of HPMCs) revealed significant association with EMT suggesting that the fibroblastoid transition from HPMCs could be affected by the amount of intraperitoneal growth factors (TGF-b, VEGF) per unit mass of HPMCs. There was significant improvement in both cell score and D-CA125 at the sixth and 12th months after switching from a high GDPs solution to a low GDPs solution. Use of icodextrin solution in patients who had average peritoneal transport showed not only better systemic effects such as decreased glucose absorption via dialysate but also preservation of the peritoneum, including less EMT and high mesothelial bulk mass. In conclusion, Therapy with low GDP solution including icodextrin may positively impact preservation of the peritoneal membrane integrity and prevention of peritoneal fibrosis with time on PD.
Absorption ; Fibroblasts ; Glucose ; Guanosine Diphosphate ; Humans ; Intercellular Signaling Peptides and Proteins ; Membranes ; Peritoneal Dialysis, Continuous Ambulatory* ; Peritoneal Fibrosis ; Peritoneum ; Transforming Growth Factor beta ; Vascular Endothelial Growth Factor A

No abstract available.
Lymphomatoid Granulomatosis*

No abstract available.
Carcinoma, Squamous Cell* ; Colon* ; Colonic Polyps* ; Female* ; Humans ; Urethra*

BACGROUND: The accuracy and efficiency of a job performed by hospital employee can be linked directly with patients' health and life. It is considered that their irregular work and stress are relatively high as compared with other workplaces. In this article we tried to look into how job stress, working environment and factors of life-style influence sleep problems in hospital employees. METHODS: This research was conducted among 248 workers of a hospital in Busan on April, 2002. Sleep problems were categorized into insomnia, sleep deprivation, daytime sleepiness and snoring on the basis of the factor analysis of 11-item questions. The job stress was proposed by Karasek, etc., and measured by 14-item modified questions. The statistical analysis was conducted using Chi-square test and multiple logistic regression analysis. RESULTS: Statistically insomnia, sleep deprivation and daytime sleepiness showed a significant increase in women (OR:2.1/2.69/3.16) and shift workers (OR:4.67/3.28/1.98) and snoring showed a significant increase in obesity (OR:5.0) and smokers (OR:2.34). CONCLUSION: This research showed that many hospital employees perceive sleep disorders as critical. Especially, work shift seemed to be an important risk factor for sleep disorders.
Busan ; Female ; Humans ; Logistic Models ; Obesity ; Prevalence* ; Risk Factors ; Sleep Deprivation ; Sleep Wake Disorders ; Sleep Initiation and Maintenance Disorders ; Snoring

BACKGROUND: Various kinds of pathogenic and non-pathogenic fungi have been isolated from the house dust, the closest environment of human beings. OBJECTIVE: Our purpose is to investigate the distribution of yeasts in house dust. METHODS: House dust was sampled from 22 families in Taegu and 56 in a rural town in Kyungpook province for 2 months from May to June, 1992. It was cultivated for years on the media containing cycloheximide (500mg/L) RESULTS: Among 78 families, 56 (71.8%) showed positive culture for yeasts in house dut;1 species in 24 (30.8%), 2 species in 19 (24.3%), 3 species in 12 (15.4%) and 4 species in 1(1.3%). Rhodotorula(Rh). Ruora was the most frequently isolated one from 36(46.2%) out of 78 families, followed by Tricosporn(T.) cutaneum 25(32.1%). Candida (C.) albicans 16 (20.5%), Pityrosporum pachydermatis 4 (5.1%) and Torulopsis candida, Cryptococcus laurentii, C. rugosa and C. guillermondii 1 (1.3%), each. CONCLUSION: Rh. rubra, T. cutaneum and C. albicans were the most important yeast species in the houst dust of both rural and raban areas.
Candida ; Cryptococcus ; Cycloheximide ; Daegu ; Dust* ; Fungi ; Gyeongsangbuk-do ; Humans ; Malassezia ; Sweat ; Yeasts*