ObjectiveTo constructe the quality-evaluation index system of clinical teaching of operating room. MethodsThe quality-evaluation indicator system was constructed using literature study and Delphi. Then the Precedence Chart and Analytic Hierarchy Process was adopted to ensure the index's weight. ResultsThe scale was formed by 5 items of level 1 and 21 items of level 2 of the index system. ConclusionThe index system has high reliability,which can be confirmed from experts' authority degree, their attentive involvement and the concentrating degree of the views. The Quality-Evaluation Index System ( QEIS ) is constructed which can be used to evaluate clinical teaching of operating room.

[Objective] To analyze the clinical risk factors for the deep vein thrombosis(DVT)after the total hip arthoplasty(THA).[Methods]Fifty-one THA in 48 patients from February 2007 to July 2007 were evaluated.Color Doppler ultrasonography was used to detect DVT of bilateral lower extremities in all patients before operatioon and at 7 days after operation.Fifteen clinical factors were examined perioperatively in order to analyze their influences on DVT formation after surgery.[Results]Seventeen patients with DVT after operation were discovered through Color Doppler ultrasonic detection,and all of the DVT occurred at the calf intermuscular vein.The incidence of the DVT in all patients was 33.3%,and 41.7% of these DVT patients were asymptomatic.Logistic regression analysis indicated that patients older than 65(OR=116.597),large volume of blood transfusion(OR=1.01)and high level of triglycerides(OR=37.249)were the risk factors for the occurrence of DVT after the THA.[Conclusion]Female,old age,obesity,increase of the level of triglycerides and cholesteral,O blood type,large volume of blood transfusion and patients with diabetes or hypertension raised possibility the occurrence of DVT.Based on this research,it concludes that patients older than 65,large volume of blood transfusion and high level of triglycerides are the risk factors for the occurrence of DVT after the THA,doctors should control the total dose of blood transfusion,to reduce the dose per time and increase the times of massive blood transfusion.Besides these,both clinicians and doctors performing Color Doppler ultrasonography should pay attention to the calf intermuscular DVT.

This article was aimed to study the inhibition of cell proliferation and induction of apoptosis by β-el-emene extract from traditional Chinese medicine (TCM) Rhizoma Zedoariae on human hepatocellular carcinoma (HepG2) cells, as well as the effect on expression of apoptosis-related proteins in liver cancer-burdened H22 mice. Human HepG2 cells were cultured in vitro. MTT method was used in the determination of β-elemene on cell prolif-eration. Apoptosis of cells were detected by the Annexin V-FITC/PI double staining method. Through the establish-ment of liver cancer-burdened H22 mice model, the inhibition of cell proliferation and induction of apoptosis-related protein expression by β-elemene on tumor-burdened mice were observed. The results showed that β-elemene inhib-ited HepG2 cell proliferation, which was dose- and time-dependent. Annexin V-FITC/PI method detected early apoptotic cells. Inhibitions of tumor growth on tumor-burdened mice from different groups were different. Inhibition of tumor growth in the high-dose β-elemene group was relatively low, and that of the middle-dose was more obvi-ous. It was concluded that β-elemene can effectively inhibit human HepG2 cells proliferation. The inhibition on pro-liferation of cancer cells was through the inducing of cell apoptosis. It was also related to the upregulation of apopto-sis-related protein Caspase-3 and downregulation of NF-κB P65.

Objective To research into the current situation of basic medicine knowledge grasp of non-medical students in local comprehensive university and to discuss the significance and necessity of launching basic medicine knowledge education in comprehensive university.Methods Random sampling was used to survey non-medical students of 1-3 grades in three gorges university with questionnaire.SPSS 13.0 software was used to do statistical analysis.Results 89.1％ undergraduates had consciousness to deal with slight illness and slight wound by themselves and 95.4％ undergraduates would prepare some drug to use when necessary.But only 37.2％ undergraduates knew the medicine classification management method of our country and 94.2％ undergraduates might abuse common medicine.96.7％ undergraduates thought that popularizing basic medicine knowledge by selected courses in university was necessary.Conclusions Most undergraduates lack basic medicine knowledge and potential medicine safety hazard like abuse medicine is existed.Education on basic medicine knowledge in university is of great significance in improving the life quality and basic quality of undergraduates.

Contraindications ; Humans ; Laryngeal Neoplasms ; classification ; pathology ; surgery ; Laryngectomy ; methods ; Neoplasm Staging

Objective To analyze the laws of acupoint selection of acupuncture for generalized anxiety disorder (GAD); To provide references for clinical treatment.Methods Computers were used to search articles about acupuncture for GAD from China National Knowledge Infrastructure (CNKI), Wanfang Database Resource System, Chinese Scientific Journal Database (VIP database) and Chinese BioMedical Literature (CBM) from their respective founding dates to Dec. 31, 2015. The corresponding database was established with NoteExpress2, and the laws of acupoints were analyzed.Results Totally 41 articles were included, including 56 acupuncture prescriptions, involving 50 acupoints in 14 meridians. The frequency for acupoint selection was 287 times. There were 49 main acupoints (225 times of acupoint selection, accounting for 98.0%) and 23 matching acupoints (62 times of acupoint selection, accounting for 46.0%) in the treatment of GAD. Main acupoints with high frequency were Baihui (GV20), Shenmen (HT07), Neiguan (PC06), Sanyinjiao (SP06) and Yintang (GV29). Matching acupoints with high frequency were Zusanli (ST36), Taichong (LR3), Neiguan (PC06), Shenmen (HT07), and Fenglong (ST40). Selecting acupoints along meridian mainly depended on Governor Meridian, Taiyang Bladder Meridian of Foot, Shaoyin Heart Meridian of Hand and Jueyin Pericardium Meridian of Hand.ConclusionPrinciples of acupuncture for GAD is treatment determination from heart and brain, emphasizing syndrome differentiation and identification of diseases, and the clinic mainly adopts acupoints along meridian with symptomatic acupoints treatment.

Objective To investigate the schistosomiasis japonica infection and preventive knowledge of immigration popula-tion in Jinshan District,Shanghai so as to provide the evidence for improving the control work. Methods The immigration popula-tion from schistosomiasis endemic provinces and local people were screened by serum IHA screening for schistosome infection, and the positives were further examined by Kato-Katz technique and the miracidium hatching method. The schistosomiasis preven-tive knowledge and behaviors were investigated by questionnaires. Results A total of 579 were investigated with 348 immigration people and 231 local people,and among them,the male accounted for 72.0%and female accounted for 28.0%. In the immigration population,the main age group was 20-29(56.0%),and 56.6%of the immigration had an education level at senior middle school or higher. The most proportion of immigration was from Anhui Province(36.2%). There were 4 IHA positive persons(1.15%)in the immigration,and 1 was positive in the stool test,and the schistosome infection rate was 0.29%. There were no positives in the local people. The schistosomiasis preventive knowledge of the immigration was generally poor,and some people’s behaviors of see doctor and medication were incorrect. Conclusion There are schistosome infected persons among the immigration population from schistosomiasis endemic provinces,and their schistosomiasis prevention knowledge was poor,thus there is a schistosomiasistransmission risk.

Objective To evaluate the efficacy and safety of local infiltration analgesia in the multimodal analgesia protocol.Methods Sixty patients who were scheduled to undergo TKA were randomly divided two groups:local infiltration analgesia (LIA) group (n=30) or the non-local infiltration analgesia (N-LIA) group (n=30).All patients were given Celecoxib 200 mg bid,3 days preoperative,and a single-injection femoral nerve block (SFNB) half an hour before the surgery (ropivacaine 3.3 g/L,30 ml).The LIA group was given local infiltration analgesia with ropivacaine (2.5 g/L,60 ml) and 0.1 mg epinephrine before suture the operative incision.The N-LIA group didn't do the LIA.Both of the two groups didn't use the patient controlled analgesia.The VAS scores,the knee joint range of motion,the muscle strength of quadriceps femoris and the side effects and complications were recorded.Results The VAS scores were lower in LIA group than in the N-LIA group,these scores at 2 h to 48 h after surgery at rest and after 24 h at motion had statistical significance.The range of motion and the muscular strength of quadriceps femoris in the LIA group were better than in the N-LIA group.In the LIA group the use of opioids was less and the side effects were lower.The average length of hospital stay after the operation was shorter in the LIA group than the N-LIA group.Conclusion This multimodal perioperative analgesia protocol that include SFNB and LIA offered improved pain control and minimal side effects to patients undergoing TKA.

English training is important for young doctors＇ career development in general hospital.The stagewise English training mode of Beijing Tiantan Hospital of Capital Medical University was introduced.By summarizing the experience of five years trial,viewpoints were brought forward that hospital English training in radiological department of general hospital should adopt a stagewise mode,create an English communication atmosphere,show the special feature of department and combine with clinical daily work.

Objective To determine the risk factors of ruptured hepatocellular carcinoma (HCC) and to study the prognostic factors of long-term survival.Methods Of the 4209 patients with HCC diagnosed and treated at the Eastern Hepatobiliary Surgery Hospital from Apr 2002 to Nov 2006,200 patients (4.8％) presented with ruptured HCC.These patients were studied retrospectively and the results of treatment were evaluated and compared with a randomly selected group of 202 patients who had no history of rupture and were treated during the study period.Results On multivariate logistic regression analysis,co-existing hypertension and cirrhosis,tumor size ＞5 cm,vascular thrombus and extrahepatic invasion were predictors of spontaneous rupture of HCC.For the 200 patients with spontaneous rupture of HCC,105 patients underwent elective one stage hepatic resection,33 received transcatheter arterial chemoembolization (TACE),and 62 were treated conservatively.The median survival time (MST) for patients with spontaneous rupture of HCC was 6 months (range,1-72 months),and the overall survival rates at 1-,3-and 5-year were 32.5％,10％ and 4％,respectively.The MST was 12 months (range,1-72 months) in the surgical group,4 months (range,1-30 months) in the TACE group and 1 month (range,0-19 months) in the conservative group.The 1-,3-and 5-year overall survival rates in patients with ruptured HCC who received partial hepatectomy were 57.1 ％,19.0％ and 7.6％,respectively,compared with 77.1％,59.8％ and 41.2％ in 98 patients who underwent partial hepatectomy for HCC without rupture (P＜0.001).Conclusions For patients with HCC who had underlying of hypertension and cirrhosis,extrahepatic invasion and tumor size ＞5 cm,there was a high propensity to rupture.Prolonged survival could be achieved in selected patients who received one-stage partial hepatectomy,although the survival results were inferior to the patients had no rupture.