Objective To analyze reasons of common malfunctions of air compressor and the handling during the mechanical ventilation for elderly patients. Methods 87 cases of malfunctions of air compressor of ventilators from June 2005 to June 2007 were analyzed. Results unsteady pressure:31cases(account for 36%); low pressure: 28 cases (account for 32%), startup failure: 15 cases (account for 18%); dead halt: 13 cases (account for 14%). Conclusion Well grasping principles of the air compressor of ventilators, and timely & correct analysis of malfunctions reasons play key roles in solving all kinds of malfunctions associated with the air compressor of ventilators.

Humans ; Hydrofluoric Acid ; Occupational Exposure ; prevention & control ; Protective Devices

Objective:Increased D-dimer level has been recently correlated with the progression and high mortality rate of some cancers. This study aimed to determine whether the plasma D-dimer level was a predictor of non-Hodgkin lymphoma (NHL). Methods:Clinical data of 425 with NHL were retrospectively reviewed. Variables such as clinicopathological factors, plasma D-dimer levels, and the international prognostic index (IPI) were evaluated. Results: The plasma D-dimer level was closely correlated with the IPI. The overall 1-, 3-, and 5-year survival rates of the low plasma D-dimer levels were 80%, 75%, and 50%;those for the high plasma D-dimer levels were 41%, 33%, and 9%, respectively (P<0.001). Compared with an IPI of zero or one, IPI values≥4 were predictive of poor prognosis (P<0.001). The Ann Arbor stage, pathological classification, plasma D-dimer level, and IPI were found to be significantly as-sociated with mortality. However, similar to IPI, the plasma D-dimer level was the independent risk factor affecting multivariate analy-sis. Conclusion:High D-dimer levels are a potential prognostic marker for NHL.

Objective To assess the usefulness video-assisted mediastinoscopy (VM) for diagnosis of disease characteristic with mediastinal mass. Analyze the correlations of clinical features of the disease with the pathologic diagnosis. Methods Between July 2000 and March 2006, 97 undiagnosed patients with mediastinal mass in chest radiography underwent biopsy of mediastinal lesions by either cervical mediastinoscopy (n=69) or parasternal mediastionoscopy (n=28). We also analyzed the correlation of symptoms, location and extent of the lesion with the pathologic diagnosis. Results All 97 patients recovered smoothly without postoperative complications. Histologic diagnosis was obtained in 96 patients. Patients with hoarse, dysphagia and superior vena cava obstruction syndrome indicate malignant lesions (26/26). The most common diseases in the super-anterior mediastinum are lymphoma(7/19), thymoma(4/19) and small cell lung cancer(SCLC) (4/19);The most common disease in the middle mediastinum are metastasis of non small cell lung cancer(11/37), sarcoidosis (9/37)and SCLC(7/37); The most possible disease involved both mediastinum and lung hilar lymph-node are scalerdosis(32/41) and SCLC(5/41). Conclusion Mediastinoscopy is effective and safe methods to establish a histologic diagnosis in patients with mediastinal mass. It is possible to make primary evaluation on some of these patients according to the typical symptoms and location, extent of the mass involvement.

Objective To evaluate the efficacy and safety of video-assisted thoracoscopic surgery in the treatment of esophageal leiomyoma.Methods Clinical data of 49 patients with esophageal leiomyoma from September 1996 to February 2009 treated by video-assisted thoracoscopic enucleation were reviewed retrospectively.Three or four trocars were used during the operation.The procedure of the surgery was similar to that of open thoracoscopic enucleation.Results In the 49 patients,video-assisted thoracoscopic leiomyoma enucleation was successfully completed in 42 cases.The other 7 patients were converted to open thoracotomy because of the following reasons:dense pleural adhesion in 2,location failure of small tumor(

Breast milk, whether the ratio of nutritional ingredients or immunological characteristics, were the most suitable for physiological needs of preterm infants. However, breast milk composition was in dynamic change, causing imbalance of energy, which could not make the premature infant to achieve the desired growth state. Human milk fortifier, retaining advantages of the breast milk, promoted growth of premature infants further. This review primarily focused on two ways of adding human milk fortifiers, standardization fortification and targeted fortification. The former was widely used in neonatal intensive care unit, while the latter was more able to explore the growth of premature infant potentially, and to achieve a more ideal ectopic growth rate. With the development of breast milk bank, storage and component extraction technology brought about donor human milk-based human milk fortifier, which provided new directions of very low birth weight infants and very preterm infants breastfeeding. The progress of human milk fortification of premature infants was closely related to expansion of multi-disciplinary centers, and only the harmonious development of multi-center maked things much more rational and systematic.

Objective: To explore the cause and the strategy for air quantity signaling in old patients using mechanic air. Method: Summary and analysis of the causes for air quantity signaling in 187 cases of old patients using respiratory machine. Results: One hundred fifty-one cases showed low-limited air quantity signaling per minute whereas 36 cases presented high-limited air quantity signaling per minute. Conclusion: Judging and removing the obstacle in respiratory machine on time and accurately are the key point raising both the survival rate of severe patients and the successful rate of mechanic air.

To investigate the inhibitory effects of RNAi expression vector on CaMKⅡ? expression of PC12 cell lines. siRNA expression vectors were constructed to be targeted directly at CaMKⅡ? gene. The recombinants were transfected into PC12 cell line with liposome. The expression of CaMKⅡ? was detected by RT-PCR and Western blot. Expression vectors could reduce the expressions of CaMKⅡ? mRNA and protein in PC12, Compared with blank vector group, the former, the ratio of inhibition of the expression of CaMKⅡ? mRNA was 46.40% and 64.69%, in 48th hour and 72th hour, the ratio of inhibitory of the expression of CaMKⅡ? protein was 74.77% in 72th hour. RNAi expression vectors can effectively inhibit the expression of CaMKⅡ? in PC12.

Objectives:To summarize the experience of nutrition management in pancreaticorenal transplantation patients. Methods:The principle of enteral nutrition before operation is high energy,rich protein and vitamin,and increased insulin usage,in order to ameliorate malnutrition for operation.Intravenous nutrition, intravenous nutrition plus enteral nutrition, and enteral nutrition were applied respectively during the postoperative stage. Results:The body weight,circumference of upper arm and skin fold thickness of triceps muscle increased in two patients,plasma albumin and hemoglobin increased in four,and total plasma protein increased in three. Conclusions:Nutrition management of the patients is very necessary for pancreaticorenal transplantation patients,and the stepwise nutrition support after operation is feasible.Appropriate calories and nutritional elements are essential to the nutrition support,and the nutritional amelioration correlates with the condition and period of nutrition support.

Objective To investigate the significance of microsatellite instability(MSI) and expressions of cyclin D1 and P53 in 7,12 dimethylbenz(a)anthracene (DMBA) induced breast carcinoma in rats. Methods Animal model of rat breast carcinoma was duplicated in 30 female Wistar rats by gastric irrigation of DMBA at the dose of 200 mg/kg. Eight microsatellite loci(D1Mitl4, D1Mgh2, D1Mgh6, D3Mit3, D3Mgh9, D5Mitll, D5Mgh5 and D7Mgh1) were selected for the examination of MSI of breast carcinoma by PCR analysis. S P immunohistochemical staining was used to study the expressions of cyclin D1 and P53 in DMBA induced breast carcinoma in rats. Results Of the 27 cases of breast carcinoma, there were 2 cases of MSI at 8 loci, 9 cases with P53 overexpression and 12 cases with cyclin D1 overexpression. All these were associated with histological grading. Conclusion MSI is infrequent in breast carcinogenesis in rats. Cyclin D1 overexpression may be the early event but P53 protein overexpression may be the late event in breast carcinoma.