2.Percutaneous stent implantation for treatment of inferior vena cave obstruction
Yongsheng LI ; Shisen JIANG ; Jian QU ; Jun XIANG
Journal of Medical Postgraduates 2005;0(S1):-
Objective: To evaluate the effects of stent implantation for treatment of Budd-Chiari syndrome. Methods:A total of 16 patients with pasthepatic inferior vena cave (IVC) obstruction syndrome were treated by balloon catheters ( Polythene and Inoue ) in percutaneous transluminal angioplasty (PTA) , then stent were inserted into the obstruction. Results: The residual pressure gradient after PTA and stent implantation was decreased from (4.6?0. 3 ) kPa to (2. 1?0. 1) kPa. The diameter of IVC after PTA and stent implantation was increased from (3.8?1. 7)mm to (14. 9?2. 0)mm. Conclusion : PTA and stent implantation are effective treatment for pasthepatic inferior vena cave obstruction.
3.Comparative analysis of percutaneous balloon pulmonary valvuloplasty for pulmonary valve stenosis by three methods
Jun XIANG ; Kang MENG ; Yaoqing ZHU ; Huagang ZHU ; Jian QU
Journal of Medical Postgraduates 2005;0(S1):-
Objective: To evaluate the effects of percutaneous balloon pulmonary valvuloplasty ( PBPV) for pulmonary valve stenosis (PS) by single-balloon, double-balloon and Inoue-balloon methods. Methods: PBPV was performed in 42 patients with PS. The systolic right ventricular pressure (SRVP) , systolic right ventricular outflow pressure and systolic pulmonary arterial pressure ( SPAP) were contrasted before and after the procedure. Systolic transpulmonary valve pressure gradient (TVPG) and total pressure gradient from right ventricular to pulmonary arterial after the procedure were compared among the three gropes. Results:SRVP, SRVOP were decreased from (14. 69?6. 01 )kPa, (12. 16?3. 48)kPa to (8.14?5.26)kPa, (5.39?2.21)kPa and PAP increased from (1.57?0.56)cm to (17. 16? 2.16)cm after PBPV, respectively. TVPGs were (2. 40?2. 05) kPa, (3. 29?2. 25 ) kPa, (2.52? 1.95)kPa and TPGs were (2. 40?2. 05)kPa, (4.98?4.26)kPa, (6.16?6.93)kPa, (5.65?4.75) kPa after PBPV by single balloon, double balloon and Inoue balloon methods, respectively. During the follow-up period (2. 5?1. 6) years, bloodflow velocity at pulmonary valve measured by supersonic Doppler decreased from (2. 38?1. 89) m/s immediately after PBPV to (2.22?1. 96) m/s, further TVPG decreasing was indicated. Conclusion: The short and long term results of PBPV for PS by each of the three methods were excellent. Inoue balloon may be the first choice for elder children and adults, while for younger children, single balloon method may be preferred. Double balloon method can be remained as the second choice when Inoue method failed.
4.Morphologic and texture features in classifying the malignant and benign breast nodules in ultrasonography
Qiuxia CHEN ; Jun XIANG ; Qi LIU ; Jian LIU
Chongqing Medicine 2014;(30):4046-4049
Objective To develop a computer-aided diagnosis(CAD)system with automatic contouring and morphologic and tex-tural analysis to aid on the classification of breast nodules on ultrasound images .Methods A modified Level Set method was pro-posed to automatically segment the breast nodules(46 malignant and 60 benign nodules) .Following ,16 morphologic features and 17 texture features from the extracted contour were calculated and principal component analysis(PCA)was applied to find the optimal feature vector dimensions .Fuzzy C-means classifier was utilized to identify the breast nodule as benign or malignant with selected principal vectors .Results The performance of morphologic features was 78 .30% for accuracy ,67 .39% for sensitivity and 86 .67%for specificity ,while the latter was 72 .64% ,58 .70% and 83 .33% ,respectively .After the combination of the two features ,the re-sult was exactly the same with the morphologic performance .Conclusion This system performs well in classifying the malignant breast nodule from the benign breast nodule .
5.Experimental study on microcoagulation of dorsal root entry zone of cervical cord with bipolar forceps
Jian-Ping XIANG ; Xiao-Lin LIU ; Jun HU ;
Chinese Journal of Microsurgery 2006;0(06):-
Objective To investigate the safety and obtain parameters of microeoagulation of dorsal root entry zone (DREZ) of cervical cord with bipolar foreps on animal model,and provide histological base for clinical application of treatment of brachial plexus avulsiol pain using microcoagulation of dorsal root entry zone.Methods On the base of swine's weight and spinal cord size in similar to human being,it was chosen to be experimental animal.The right DREZs of cervical cord were microcoagulated with bipolar forceps.The swines were fed in normal way.Their activities were observed.The mass change of the cervical cord segment were observed after 3 weeks and the cervical cord segment was fixed with 10% fromalin,paraffin sliced,HE dying.Coagulating space,depth and width were measured under microsope.The coagulating parameter were adjusted according to measuring outcome in order to achieving a most avaliable parameter.Results All post-op swine survived.When the microcogulation were made with bipolar forceps adopted following parame- ters:The distance of between the polar was 2.0 mm;The diameter of polar was 0.3 mm.The inserting depth 2 mm,the coagulated power 18 watt,the coagulated time was 2 second,then the width of lesions of DREZ in cross section was 1.15 mm and the depth of lesions was 3.10 mm,which was consistent with the area of hu- man DREZ of cervical cord.Conclusion The experiment on swine suggested,microcoagulation of DREZ by bipolar forceps is safe and no mortal complications when the testified parameters are adoped,and can achieve the area of DREZ of cervical cord in human.
6.Progress in research on mechanism of pathogenesis and treatment of acute paraquat poisoning.
Yan-jun RUAN ; Xiang-dong JIAN ; Guang-ran GUO
Chinese Journal of Industrial Hygiene and Occupational Diseases 2009;27(2):114-116
Herbicides
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poisoning
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Humans
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Paraquat
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poisoning
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Poisoning
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metabolism
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pathology
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therapy
7.Effects of Different Media on Enriching and Screening Fungi Culture with the Abilities of Decolorizing Various Synthetic Dyes
Zhen-Jie JIA ; Hui-Jun LI ; Qing-Xiang YANG ; Hao ZHANG ; Jian-Jun CHEN ;
Microbiology 1992;0(04):-
In this paper 3 different media (A,for yeast cultivation ; B, for laccase producing; D, for white rot fungi cultivation) were compared in enriching and screening decolorizing fungi culture using Reactive Black 5 (RB5) and Reactive Red (M-3BE) from the following three points: decolorization effects, abilities of producing enzymes and diversity of microbial community. 11 groups of fungi with obvious decolorization effects were obtained after enrichment for near one month. Among them, 6 groups came from medium D, the other two 3 groups from medium A and B, respectively. However, the 3 groups from medium A exhibited the highest microbial diversity and best decolorization results with 99.53% and 97.42% color removal rate of Reactive Red M-3BE and Acid Red. From them, 16 strains of fungi were isolated and primarily identified as Saprolegniaceae, Eurotiaceae (Monascus went), Erysiphaceae and Physodermataceae. Fungi groups from medium B and D exhibited a bit lower color removal rate of various dyes and only 3 and 2 isolates primarily classified as Saccharomycetaceae and Eurotiaceae (Penicillium) were obtained from them. Fungi cultures in medium A and B could produce lignin peroxidase, and those in medium D could be detected higher activity of laccase. All the fungal cultures exhibited very weak activity of manganese dependant peroxidase.
8.Short-Term Effect of Conformal Radiotherapy for Recurrent Nasopharyngeal Carcinoma
Shao-Jun LIN ; Jian-Ji PAN ; Jun-Xin WU ; Xiang-Song LIN
Chinese Journal of Cancer 2001;20(2):171-174
Objective: The current study was designed to evaluate the treatment results of nasopharyngeal carcinoma by conformal radiotherapy. Methods: From September 1997 to February 2000, a total of 41 cases of recurrent nasopharyngeal carcinoma were treated by conformal radiotherapy. Among them, 27 cases were treated by late-course hypofraction conformal radiotherapy with the dose of 20- 24 Gy at 80% isodose, 4- 7 Gy per time, following routine radiotherapy of 39 Gy/30f/3weeks. Fourteen cases received total-course conformal radiotherapy with the dose of 59.8 Gy/46f/4.6weeks at 90% isodose. Results: The reference isodose curves conform to the target in three dimensions in conformal radiotherapy. The acute radiation mucositis, cranial nerve paralysis and trismus incidence were similar in two groups, however, in the hypofractionation group 22% developed necrosis of nasopharyngeal mucosa, 3.7% developed reduced optic nerve lesion, whereas none of the hyperfractionation group had these complications. The tumor response rate were both 93% for two groups. Conclusion: Hyperfraction conformal radiotherapy is effective in the treatment of recurrent nasopharyngeal carcinoma and has relatively lower incidence of radiation complication.
10.Two structural predictors of visual outcome of idiopathic epiretinal membrane surgery
International Eye Science 2018;18(1):166-168
AIM:To evaluate two structural predictors of visual outcome of epiretinal membrane surgery.METHODS:Retrospective study for 30 eyes of epiretinal membrane surgery between January 2014 and October 2016.We assessed the related parameters of the optical coherence tomography and recorded the best-corrected visual acuity(BCVA) at baseline and 1,3 and 6mo after surgery.Correlations between the final best-corrected visual acuity and photoreceptor integrity status or photoreceptor outer segment length were investigated.RESULTS:Average best-corrected visual acuity decreased at 1mo postoperatively compared with baseline,but improved at 3 and 6mo.Central macular were more sweller at 1mo postoperatively than baseline,but a significant thickeness reduction was found at 6mo (P< 0.05).Photoreceptor outer segment length were shortened at 1 mo compared with preoperation (P<0.05),gradually approached the baseline level at 3 and 6mo.Multivariate regression the final best-corrected visual acuity associated with photoreceptor integrity and photoreceptor outer segment length (P=0.023,0.004).CONCLUSION:Photoreceptor integrity and photoreceptor outer segment length detected by OCT were significant predictors of the final best-corrected visual acuity(BCVA) after idiopathic epiretinal membrane surgery.