1.No title in English
Journal of the Korean Medical Association 1997;40(6):707-712
No abstract available.
2.Treatment of flail chest with Judet's strut.
Byung Soon PARK ; Yong Jun CHO ; Dong Jun LEE
The Korean Journal of Thoracic and Cardiovascular Surgery 1991;24(4):366-370
No abstract available.
Flail Chest*
3.The effects of lidocaine on blood pressure and heart rates after nasotracheal intubation.
Kwang Won YUM ; Yong Seok CHO ; Jun Young YOU
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1992;18(1):12-17
No abstract available.
Blood Pressure*
;
Heart Rate*
;
Heart*
;
Intubation*
;
Lidocaine*
4.A clinical observation on hearing disturbance in patients with diabetes mellitus.
Sang In NAM ; Jae Min CHO ; Jung Yong OH ; Kyoung Jun PARK ; Chin Kyu CHO
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(4):640-650
No abstract available.
Diabetes Mellitus*
;
Hearing*
;
Humans
5.The Diagnostic Value of the Nitroblue Tetrazolium Dye Reduction Test in Orthopaedic Field
Key Yong KIM ; Duk Yun CHO ; Jang Kyu PARK ; Byoung Soo PARK ; Myoung Jun CHO
The Journal of the Korean Orthopaedic Association 1976;11(1):98-103
Nitroblue tetrazolium dye reduction test is now widely used for early detection of bacterial infection. Practically nitroblue tetrazolium dye reduction test (N.B.T. test) gives certain clue to rule out any possibility of aseptic inflammation. Authors performed N.B.T. test for 80 orthopaedic diseases and 40 controls, and the results were as followings: 1. Forty-one of 60 subjects with bacterial infection had more than 10% formazan positive neutrophils, and 18 of 20 subjects without bacterial infection showed less than 10%. formazan positive neutrophils, The groups of the elevated N.B.T. responses were mainly the subjects who had osteomyelitis, soft tissue inflammation, pyogenic arthritis, and bone and joint tuberculosis. 2. The mean proportion of N.B.T. positive neutrophils was 3.8±2.78% in 40 controls, 4.7±4.23% in 20 nonifectious group 12.7±10.3% in 12 chronic osteomyelitis, 12.5±10.7% in 15 treated bone and joint tuberculosis, 20.9±15.65% in 15 untreated bone and joint tuberculosis and 20±10.70% in 11 pyogenic arthritis and 7 other soft inflammatory group. 3. In noninfectious group, 7 of 8 subjects with elevated ESR and 3 of 4 subjects with elevated body temperature revealed N.B.T. responses less than 10%. 4. In 23 subjects with the elevated N.B.T. responses as well as leukecytosis, 22 subjects were the groups of bacterial infection and rest 1 was noninfectious in nature. 5. Therefore, the N.B.T. test is found to be useful for the purposes of the early diagnostic aid of the bacterial infection and differential diagnosis between bacterial infections and other diseases.
Arthritis
;
Bacterial Infections
;
Body Temperature
;
Diagnosis, Differential
;
Inflammation
;
Neutrophils
;
Nitroblue Tetrazolium
;
Osteomyelitis
;
Tuberculosis, Osteoarticular
6.Simple Advertent Hysterectomy in the Presence of Invasive Cervical Cancer.
Jae Kwan LEE ; Jun Young HUR ; Yong Kyun PARK ; Soo Yong CHO ; Ho Suk SAW
Korean Journal of Obstetrics and Gynecology 2000;43(5):891-896
To identify significant prognostic factors in patients undergoing simple hysterectomy in the presence of invasive cervical cancer, the records of 45 patients who had taken such a procedure between 1993 and 1997 were reviewed. Overall relapse-free survival and 5-year survival rates were 91.1 and 92.1%, respectively. Factors found to be significantly related to survival were the retrospectively determined stage(p=0.0000), the presence of residual disease(p=0.0001), and cell type(p=0.0000). By multivariate analysis, factor emerging as significantly detrimental to survival was the cell type. The presence of residual disease was a marginally significant factor(p=0.067). The expectations for survival of patients with residual tumor mass and/or with adenocarcinoma after simple hysterectomy appear to be markedly worse than those with others, so radical reoperation should be considered in those patients.
Adenocarcinoma
;
Humans
;
Hysterectomy*
;
Multivariate Analysis
;
Neoplasm, Residual
;
Reoperation
;
Retrospective Studies
;
Survival Rate
;
Uterine Cervical Neoplasms*
7.Clinical Usefulness of Low Calcium Dialysate in CAPD Patients with High Risk of Low-turnover Bone Disease.
Young Jun CHO ; Hyuk Jun CHOI ; Ji Hyung CHO ; Min Hwa JANG ; Yong Bong SIN ; Sun Hee PARK ; Duk Hyun LEE ; Seong CHO ; Yong Lim KIM ; Dong Kyu CHO
Korean Journal of Nephrology 2001;20(6):975-980
Hypercalcemia is a common complication in CAPD patients treated with calcium-containing phosphate binders and using the standard dialysate(Ca++ : 3.5 mEq/L). Furthermore, the high calcium concentration in standard dialysate may have a suppressive effect on parathyroid hormone(iPTH) level, contributing to the high prevalence of low-urnover bone disease. We studied the effect of low calcium dialysate(Ca++ : 2.5 mEq/L) for those patients with high risk of low- turnover bone disease. Among 386 patients(1996. 1.- 1999. 12.) who had been stable on CAPD for at least 3 months, 46 patients were included in this study. The patients were divided into 3 groups on the basis of the iPTH levels(<150 pg/mL) and/or corrected serum calcium levels(>10 mg/dL) before the conversion to low calcium dialysate. Group 1(n=29), iPTH <150 pg/mL and Ca++>10 mg/dL; Group 2 (n=14), iPTH <150 pg/mL and Ca++<10 mg/dL; Group 3(n=3), iPTH >150 pg/mL and Ca++ >10 mg/ dL. During a 2-month run-in period, those patients were treated with standard dialysate. After that, a 12-month therapy with low calcium dialysate was followed. Biochemical data including calcium, phosphorus, iPTH and alkaline phosphatase were measured regularly and daily phosphate binder and calcitriol intake(pill counting) were assessed during the run-in and therapy period. We obtained the following result: the prevalence of hypercalcemia(Ca++>10.5 mg/dL) was 5.7%(22/ 386 patients). Serum calcium levels decreased during the therapy period(12 months)(10.5+/-1.4 vs 9.4+/-1.3 mg/dL, p<0.05). Serum phosphorus levels remained unchanged. Mean serum alkaline phosphatase level increased(203.0+/-92.9 vs 257.2+/-103.4 U/L, p<0.05). Serum iPTH levels increased (92.7+/-128.8 vs 225.3+/-237.3 pg/mL,p<0.05). The mean intake of oral phosphate binders was not significantly different between run-in period and therapy period. But calcitriol doses increased 0.038+/-0.087 at run-in period to 0.158+/-0.288 tablets/person/day at therapy period(p<0.05). In the six patients, low calcium dialysate was converted to standard dialysate due to high iPTH level (n=3), symptomatic hypo calcemia(n=2), and uncontrolled edema(n=1). In conclusion, in the study of 46 patients over 12 month period, the usage of 2.5 mEq/L calcium dialysate resulted in a significant decrement in calcium levels and increased iPTH levels. Therefore, we propose that dialysis with a low calcium dialysate is an acceptable form of therapy for the patients with high risk of low-turnover bone disease showing hypercalcemia and low iPTH level. However, further study will be needed for evaluating the effect of low calcium dialysate in low-turnover bone disease.
Alkaline Phosphatase
;
Bone Diseases*
;
Calcitriol
;
Calcium*
;
Dialysis
;
Humans
;
Hypercalcemia
;
Peritoneal Dialysis, Continuous Ambulatory*
;
Phosphorus
;
Prevalence
8.Molecular Targeting of ERKs/RSK2 Signaling Axis in Cancer Prevention.
Sun Mi YOO ; Sung Jun CHO ; Yong Yeon CHO
Journal of Cancer Prevention 2015;20(3):165-171
RSK2 is a downstream signaling protein of ERK1 and ERK2 and plays a key role in physiological homeostasis. For this reason, RSK2 is a highly conserved protein among the p90RSK family members. In its location in the signaling pathway, RSK2 is a kinase just upstream of transcription and epigenetic factors, and a few kinases involved in cell cycle regulation and protein synthesis. Moreover, activation of RSK2 by growth factors is directly involved in cell proliferation, anchorage-independent cell transformation and cancer development. Direct evidences regarding the etiological roles of RSK2 in cancer development in humans have been published by our research group illustrating that elevated total- and phospho-RSK2 protein levels mediated by ERK1 and ERK2 are higher in skin cancer tissues compared to normal skin tissues. Notably, it has been shown that RSK2 ectopic expression in JB6 Cl41 cells induces cell proliferation and anchorage-independent cell transformation. Importantly, knockdown of RSK2 suppresses Ras-mediated foci formation and anchorage-independent colony growth of cancer cells. Kaempferol is a one of the natural compounds showing selectivity in inhibiting RSK2 activity in epidermal growth factor-induced G1/S cell cycle transition and cell transformation. Thus, ERKs/RSK2 signaling axis is an important target signaling molecule in chemoprevention.
Axis, Cervical Vertebra*
;
Carcinogenesis
;
Cell Cycle
;
Cell Proliferation
;
Cell Transformation, Neoplastic
;
Chemoprevention
;
Epigenomics
;
Homeostasis
;
Humans
;
Intercellular Signaling Peptides and Proteins
;
Phosphotransferases
;
Skin
;
Skin Neoplasms
9.Role of Lumbar Puncture in Children with First Febrile Convulsion.
Kyu Chul CHOI ; Byoung Soo CHO ; Sa Jun CHUNG ; Yong Mook CHOI ; Chang Il AHN
Journal of the Korean Pediatric Society 1984;27(7):718-724
No abstract available.
Child*
;
Humans
;
Seizures, Febrile*
;
Spinal Puncture*
10.A Case of Congenital Long OT Syndrome with Pseudo - Atrioventricular Block.
Kyoung Hi JEON ; Yong Woon BACK ; Hyun Kee CHUNG ; Tae Jun CHA ; Sung Rae CHO
Journal of the Korean Society of Neonatology 1999;6(2):263-267
The congenital long-QT syndrome (LQTS) is characterized by recurrent syncope, prolonged QT intervals, QT interval lability, polymorphic ventricular tachycardia, and sudden death. We report a case of congenital long QT syndrome in a 28-day-old male infant who presented with syncope, bradycardia with 2: 1 pseudo-atrioventricular block and a markedly prolonged QT inteval. One episode occured after crying and degenerated into ventricular fibrillation and terminated after cardioversion. A VVI type cardiac pacemaker was implanted. Subsequently, the infant's heart rate was over 110/min and 2: 1 AV block and any other arrhythmia were absent. The infant recovered from the accompanied pneumonia and sepsis and was discharged 47 days after adrnission. However, 13 days after discharge, the infant returned to our hospital ER with syncope. Ventricular fibrillation ceased after cardioversion. Despite medication with propranolol, ventricular tachycardia persisted. The infant expired the day after he was discharged against medical advice.
Arrhythmias, Cardiac
;
Atrioventricular Block*
;
Bradycardia
;
Crying
;
Death, Sudden
;
Electric Countershock
;
Heart Rate
;
Hospitals
;
Humans
;
Infant
;
Long QT Syndrome
;
Male
;
Pneumonia
;
Propranolol
;
Sepsis
;
Syncope
;
Tachycardia, Ventricular
;
Ventricular Fibrillation