Nevus lipomatosus superficialis presented as soft, yellowish papules or cerebriform plaques occurring usually on the buttock or thigh, less often on the ear or scalp. We herein report a case of nevus lipomatosus superficialis on the leg.
Buttocks ; Ear ; Leg* ; Nevus* ; Scalp ; Thigh

Objectives: Addiction to prescription narcotics is a global issue, and detecting individuals with narcotic use disorder (NUD) at an early stage can help prevent narcotics misuse and abuse. We developed a novel index for the early detection of NUD based on an analysis of real-world prescription patterns in a large hospital. Methods: We analyzed the narcotic prescriptions of 221,887 patients, prescribed by 8,737 doctors from July 2000 to June 2018. To facilitate the early detection of patients at risk of developing NUD after a prolonged period of narcotic use, we developed a weighted morphine equivalent daily dose (wt-MEDD) score. This score was based on the number of prescription dates where the actual MEDD exceeded the intended MEDD. We compared the performance of the wt-MEDD scoring system in identifying patients diagnosed with NUD by doctors against other high-risk NUD indices.These indices included the MEDD scoring system, the number of days on prescribed narcotics, the frequency and duration of prescriptions, narcotics prescriptions from multiple doctors, and the number of early narcotic refills. Results: A wt-MEDD score cut-off value of 10.5 successfully identified all outliers and diagnosed patients with NUD with 100% sensitivity and 99.6% specificity. This score demonstrated the highest sensitivity and specificity for detecting NUD compared to all other indexes. The predictive performance was further improved by combining the wt-MEDD score with other high-risk NUD indexes. Conclusion We developed a novel index, the wt-MEDD score, which showed excellent performance in the early detection of NUD.

Objectives: Addiction to prescription narcotics is a global issue, and detecting individuals with narcotic use disorder (NUD) at an early stage can help prevent narcotics misuse and abuse. We developed a novel index for the early detection of NUD based on an analysis of real-world prescription patterns in a large hospital. Methods: We analyzed the narcotic prescriptions of 221,887 patients, prescribed by 8,737 doctors from July 2000 to June 2018. To facilitate the early detection of patients at risk of developing NUD after a prolonged period of narcotic use, we developed a weighted morphine equivalent daily dose (wt-MEDD) score. This score was based on the number of prescription dates where the actual MEDD exceeded the intended MEDD. We compared the performance of the wt-MEDD scoring system in identifying patients diagnosed with NUD by doctors against other high-risk NUD indices.These indices included the MEDD scoring system, the number of days on prescribed narcotics, the frequency and duration of prescriptions, narcotics prescriptions from multiple doctors, and the number of early narcotic refills. Results: A wt-MEDD score cut-off value of 10.5 successfully identified all outliers and diagnosed patients with NUD with 100% sensitivity and 99.6% specificity. This score demonstrated the highest sensitivity and specificity for detecting NUD compared to all other indexes. The predictive performance was further improved by combining the wt-MEDD score with other high-risk NUD indexes. Conclusion We developed a novel index, the wt-MEDD score, which showed excellent performance in the early detection of NUD.

Objectives: Addiction to prescription narcotics is a global issue, and detecting individuals with narcotic use disorder (NUD) at an early stage can help prevent narcotics misuse and abuse. We developed a novel index for the early detection of NUD based on an analysis of real-world prescription patterns in a large hospital. Methods: We analyzed the narcotic prescriptions of 221,887 patients, prescribed by 8,737 doctors from July 2000 to June 2018. To facilitate the early detection of patients at risk of developing NUD after a prolonged period of narcotic use, we developed a weighted morphine equivalent daily dose (wt-MEDD) score. This score was based on the number of prescription dates where the actual MEDD exceeded the intended MEDD. We compared the performance of the wt-MEDD scoring system in identifying patients diagnosed with NUD by doctors against other high-risk NUD indices.These indices included the MEDD scoring system, the number of days on prescribed narcotics, the frequency and duration of prescriptions, narcotics prescriptions from multiple doctors, and the number of early narcotic refills. Results: A wt-MEDD score cut-off value of 10.5 successfully identified all outliers and diagnosed patients with NUD with 100% sensitivity and 99.6% specificity. This score demonstrated the highest sensitivity and specificity for detecting NUD compared to all other indexes. The predictive performance was further improved by combining the wt-MEDD score with other high-risk NUD indexes. Conclusion We developed a novel index, the wt-MEDD score, which showed excellent performance in the early detection of NUD.

Objectives: Addiction to prescription narcotics is a global issue, and detecting individuals with narcotic use disorder (NUD) at an early stage can help prevent narcotics misuse and abuse. We developed a novel index for the early detection of NUD based on an analysis of real-world prescription patterns in a large hospital. Methods: We analyzed the narcotic prescriptions of 221,887 patients, prescribed by 8,737 doctors from July 2000 to June 2018. To facilitate the early detection of patients at risk of developing NUD after a prolonged period of narcotic use, we developed a weighted morphine equivalent daily dose (wt-MEDD) score. This score was based on the number of prescription dates where the actual MEDD exceeded the intended MEDD. We compared the performance of the wt-MEDD scoring system in identifying patients diagnosed with NUD by doctors against other high-risk NUD indices.These indices included the MEDD scoring system, the number of days on prescribed narcotics, the frequency and duration of prescriptions, narcotics prescriptions from multiple doctors, and the number of early narcotic refills. Results: A wt-MEDD score cut-off value of 10.5 successfully identified all outliers and diagnosed patients with NUD with 100% sensitivity and 99.6% specificity. This score demonstrated the highest sensitivity and specificity for detecting NUD compared to all other indexes. The predictive performance was further improved by combining the wt-MEDD score with other high-risk NUD indexes. Conclusion We developed a novel index, the wt-MEDD score, which showed excellent performance in the early detection of NUD.

Objectives: Addiction to prescription narcotics is a global issue, and detecting individuals with narcotic use disorder (NUD) at an early stage can help prevent narcotics misuse and abuse. We developed a novel index for the early detection of NUD based on an analysis of real-world prescription patterns in a large hospital. Methods: We analyzed the narcotic prescriptions of 221,887 patients, prescribed by 8,737 doctors from July 2000 to June 2018. To facilitate the early detection of patients at risk of developing NUD after a prolonged period of narcotic use, we developed a weighted morphine equivalent daily dose (wt-MEDD) score. This score was based on the number of prescription dates where the actual MEDD exceeded the intended MEDD. We compared the performance of the wt-MEDD scoring system in identifying patients diagnosed with NUD by doctors against other high-risk NUD indices.These indices included the MEDD scoring system, the number of days on prescribed narcotics, the frequency and duration of prescriptions, narcotics prescriptions from multiple doctors, and the number of early narcotic refills. Results: A wt-MEDD score cut-off value of 10.5 successfully identified all outliers and diagnosed patients with NUD with 100% sensitivity and 99.6% specificity. This score demonstrated the highest sensitivity and specificity for detecting NUD compared to all other indexes. The predictive performance was further improved by combining the wt-MEDD score with other high-risk NUD indexes. Conclusion We developed a novel index, the wt-MEDD score, which showed excellent performance in the early detection of NUD.

Fractures and fracture-dislocations of the ankle are caused by a variety of mechanisms. In addition to fractures, injuries of soft tissue, such as ligaments, tendons, nerves, and muscles may also occur. Among these, a tibialis posterior tendon injury is difficult to be identified due to swelling and pain at the fracture site. It is difficult to observe tibialis posterior tendon injury on a simple radiograph; it is usually found during surgery by accident. There are some studies regarding irreducible ankle fracture-dislocations due to interposition of the tibialis posterior tendon; however, to the best of our knowledge, there has not been any report about interposition of injured tibialis posterior tendon. Herein, we report a case of an irreducible fracture-dislocation of the ankle due to injured tibialis posterior tendon interposition that was observed intraoperatively, interrupting the reduction of ankle fracture-dislocation. We obtained satisfactory clinical result after reduction of the trapped tendon, fracture reduction, and internal fixation; therefore, we are willing to report this case with the consent of the patient. This study was conducted with an approval from the local Institutional Ethics Review Board.
Ankle Fractures* ; Ankle* ; Dislocations* ; Ethics, Institutional ; Humans ; Ligaments ; Muscles ; Tendon Injuries ; Tendons*

OBJECTIVE: In recent years, the neurosurgeon's role in managing cerebrovascular diseases (CVD) has becomes rapidly challenged and overlapped with other specialists. Furthermore, the patterns of CVD and patient recruitment have also changed. We conducted a retrospective study regarding the practical trends of CVD with reference to the management paradigms at our institute. METHOD: We reviewed all the available data, including the annual reports, the daily department records, the medical records and the radiographic films of the CVD patients who had been admitted to our Neurosurgery Department during the five years between Jan. 2004 and Dec. 2008. RESULTS: The total numbers of CVD operations showed a slight initial increase, but then they remained steady for the latter 3 years. The number of cases of non-angiomatous hemorrhage has been relatively steady, regardless of surgery. The total numbers of treated aneurysms increased, but the main body of this increment was attributed to the initiation of endovascular treatment and increased identification of unruptured vascular lesions. Vascular malformations were sustained with a small number of cases due to referring them to other institutes for radiosurgery, except for the cases that required urgent hemorrhagic evacuation. CONCLUSION: Hemorrhagic CVDs tended to decrease either due to increasing identification before rupture or shifting such patients into a large volume hospital. The increasing awareness of ischemic CVD, the early detection of unruptured aneurysms, and the separation of medical responsibilities from neurologists have all pushed neurosurgeons to make treatment plans in a more cooperative fashion, instead of a competitive way. Neurosurgeons should be furnished with several revolutionary surgical options to widen their scope of managing patients with CVD.
Academies and Institutes ; Aneurysm ; Hemorrhage ; Humans ; Infarction ; Intracranial Aneurysm ; Medical Records ; Neurosurgery ; Patient Selection ; Radiosurgery ; Retrospective Studies ; Rupture ; Specialization ; Subarachnoid Hemorrhage ; Vascular Malformations ; X-Ray Film

With the development of body sensor technology, wearable health monitoring systems have been an emerging information technology in the 'ubiquitous health care' system. Wearable sensors enable long-term continuous physiological monitoring important in health promotion and management of many chronic disorders. In this paper, we present several wearable health monitoring systems developed by different countries and discuss emerging opportunities, as well as, existing challenges such as standardization, administration, validation, and discrepancy issues between technology and clinical implication.
Health Promotion ; Monitoring, Physiologic ; Telemedicine

Mumps orchitis represents the most common complication of mumps infections and occurs in 5 to 37% of the populations. The most important danger is the risk of testicular atrophy up to 50% of affected testis which results in sterility. Two patients with mumps orchitis received systemic treatment with Interferon-alpha2(INF-alpha2)(3x06IU per day) for 7 days. All acute symptoms and signs of mumps orchitis disappeared within 4-7 days of INF-alpha2 therapy. No incidence of testicular atrophy was observed at the 19 and 6 months follow-up, respectively. No significant adverse effects of drug were occurred during treatment. We recommend the immediate interferon therapy, as soon as mumps orchitis manifests, to relieve clinical manifestation and to prevent testicualr atrophy and resulting infertility.
Atrophy ; Follow-Up Studies ; Humans ; Incidence ; Infertility ; Interferons ; Male ; Mumps* ; Orchitis* ; Testis