1.Clinical Features of Morbilliform Erythema in Patients with Systemic Lupus Erythematosus.
Korean Journal of Dermatology 1998;36(2):236-240
BACKGROUND: In patients with systemic lupus erythematosus(SLE), LE-specific cutaneous lesions include malar rashes, widespread/morbilliform erythema, oral ulcer and bullous lesions. OBJECTIVE: Clinical observations were carried out to define cutaneous features of morbilliform erythema and to see possible relevancy of this erythema to disease activity of SLE. METHODS: Examinations were performed on 7 SLE patients with morbilliform erythema regarding the distribution and course of the cutaneous lesions; some SLE-activity related hematologic/immunologic data taken during/around the time of this skin disease were also assessed in each patient. RESULTS: In most of those patients with morbilliform erythema, which covered the trunk and extremities, the skin lesions lasted for about 2 weeks until their disappearance. At or around the time of suffering from this skin disease of acute eutaneous LE, activities of systemic disease were recognized as "in a state of flare-up or aggravation" with hypocomplementemia and high titers of anti-nDNA autoantibodies. CONCLUSION: As with malar rashes, morbilliform erythema of acute cutaneous LE seems to develop more frequently at the time of severe systemic involvement of immunopathological processes of SLE.
Autoantibodies
;
Blister
;
Erythema*
;
Exanthema
;
Extremities
;
Humans
;
Lupus Erythematosus, Systemic*
;
Oral Ulcer
;
Skin
;
Skin Diseases
2.The measurement of aflatoxin B in urine of some Korean.
Journal of the Korean Surgical Society 1992;42(3):376-390
No abstract available.
Aflatoxin B1*
;
Aflatoxins*
4.Autologous Vs Allogenic Chondrocytes Transplantation for Full Thickness Chondral Defects in Rabbit's Patella.
Jun Seop JAHNG ; Jin Woo LEE ; Woo Ick YANG
The Journal of the Korean Orthopaedic Association 1998;33(2):433-444
Biologic resurfacing of the damaged joints is an area of great interest and clinical promise because of the limited potential ofdamaged articular cartilage healing. Several methods such as spongiolization. joint dehridement and ahrasion of suhchondral hone. perichondral grafts, and osteochondral grafts have heen used to repair cartilage defects, but the results were not satisfactory. Rccently autologous chondrocyle transplantation with a pcrioslcal patch was paid an altention for its advantage , the regeneration with hyalin cartilage. But it have many disadvantages such as too expensive cost. second staged operation, and technically difficult to isolatc chondrocytes from a small volume of donor site, so we performed that a definecl cartilaee delect in the ribbit patella was treated with transplanta1ion of in virto expanded allogenic chondrocvtes and then compared with an autologous chondrocytes transplantation. Adult rabbits were used to transplant autogenously and allogenously and allogenically harvested and in vitro cultured chondrocytes into patellar chondral lesions that had been made previously 3x 3mmin size , extending down to the calcified zone. Chondrocytes were isolated in the femoral condyle of the opposite knee or othe rabbit knee. And then enzymatic digestion ( collagenase A and DNase I ) was performed for 5 hours room temperature in a spinner bottle and cells were seeded in a 25cm2 culture flask in Dulheccos modified essential medium (DMEM), supplemented with l0% fetal hovine serum (FBS). The culture medium was changed twice weekly. After 14 days of culture, the cells were isolated hy irypsinization and transplanted into previously made chondral defects with an autogenous periosteal patch taken from the medial aspect of tibia. Healing ol' the defects was assessed by gross examination, immunohistochemical stain, and light microscope with hematoxylin-eosin stain at 8, 16, and 24 weeks. Allogenic and autologous chondrocytes transplantation significantly increased the amount of newly tormed repair tissue compared to that found in control knees in which the Jesion was solely covered hy a periosteal patch. The repair tissue, however, had a tendency of incomplete bonding to adjacent cartilage. This study shows that allogenic and autologous articular chondrocytes that have heen expanded for 2 weeks in vitro can stimulate the healing phase of chondral lesion. There is no signilicant diffcrence hetween allogenic and autologous chondrocytes transplantation.
Adult
;
Cartilage
;
Cartilage, Articular
;
Chondrocytes*
;
Collagenases
;
Deoxyribonuclease I
;
Digestion
;
Humans
;
Hyalin
;
Joints
;
Knee
;
Patella*
;
Rabbits
;
Regeneration
;
Tibia
;
Tissue Donors
;
Transplants
5.Psychiatric Diagnosis and Hypersexual Behavior Inventory, Sexual Addiction Screening Test, and Beck Depression Inventory/Beck Anxiety Inventory of the Sexual Offenders.
Jun Hyung LEE ; Hyun Sic KIM ; Jae Woo LEE ; Woo Sung PARK ; Myung Ho LIM
Korean Journal of Legal Medicine 2013;37(1):27-33
The current study evaluated DSM-IV psychiatric diagnoses and investigated the psychological characteristics of sexual offenders by using the Hypersexual Behavior Inventory(HBI), Sexual Addiction Screening Test (SAST), Beck Depression Inventory (BDI), and Beck Anxiety Inventory (BAI). Fifty male sexual offenders and 36 male healthy controls completed the psychiatric diagnosis and 30 of the 50 male sexual offenders completed the psychological tests listed above. Thirty-two of the 50 sexual offenders were patients with paraphilias, these sexual offenders had been admitted by the Ministry of Justice to the Institute for Forensic Psychiatry in Gongjui-si due to sexual violence. Participants displayed high lifetime rates of psychiatric disorders: 32 (64%) had paraphilias, 16 (32%) had depressive disorders, 10 (20%) had anxiety disorders, 9 (18%) had impulse control disorders, 6 (12%) had schizophrenia, 2 (4%) had bipolar disorders, and 16 (32%) had personality disorders or some other Axis II disorder. Scores for the sexual offenders were significantly higher both on the HBI and the SAST than the comparison group. Scores for the sexual offenders were also higher for the BDI and the BAI as compared to the control group, but this difference was not statistically significant. Results indicate that sexual offenders may have sexual addictions and be hypersexual. In addition to depressive and anxious psychopathologies, they also seem to have sexual psychopathologies. These results suggested that the psychopathology of sexual offenders may be different than that of a control group.
Anxiety
;
Anxiety Disorders
;
Axis, Cervical Vertebra
;
Bipolar Disorder
;
Criminals
;
Depression
;
Depressive Disorder
;
Diagnostic and Statistical Manual of Mental Disorders
;
Forensic Psychiatry
;
Humans
;
Disruptive, Impulse Control, and Conduct Disorders
;
Male
;
Mass Screening
;
Mental Disorders
;
Paraphilic Disorders
;
Personality Disorders
;
Psychological Tests
;
Psychopathology
;
Schizophrenia
;
Sex Offenses
;
Social Justice
6.A Case of Tick Bite.
Baik Kee CHO ; Jun Young LEE ; Jin Woo KIM
Korean Journal of Dermatology 1985;23(4):480-485
We describe herein a case of tick bite ocurring to a 23-year-old man who has a characteristic lesion clinically and histopathologically. The tick(Ixodes sp.) was still attached to the brownish and erythematous, indurated skin of the scrotum. The engorged tick which was carefully removed from the skin with a scalpel was 8.7mm in length and 5. 5 mm in width. Histopathologically, characteristic amorphous eosinophilic materigl is deposited around a round space where the hypostorne of the tick was inserted. Heavy inflammatory cell infiltratton in the mid and lower dermis is composed mainly of neutrophils and eosinophils. A certain area of the lower dermis shows edema and capillary dilatation along with the mixed inflammatory cell infiltration, TVide excision of the indurated lesion including the tick was done. The clinical and hsitopathological findings of the tick bite was discussed.
Capillaries
;
Dermis
;
Dilatation
;
Edema
;
Eosinophils
;
Humans
;
Neutrophils
;
Scrotum
;
Skin
;
Tick Bites*
;
Ticks*
;
Young Adult
7.A Case of Streptococcus Agalactiae Pneumonia In An Adult Diabetic Man.
Choon Sik PARK ; Jee Yun LEE ; Jun Hee WOO
Tuberculosis and Respiratory Diseases 1994;41(2):165-170
Despite significant advances in obstetric and pediatric health care, Streptococcus agalactiae(Lancefield group B β-hemolytic Streptococcus, GBS) remains one 91 the most prevalent and devastating pathogens in peripartum women and their newborn infants. It may cause urinary tract infection, chorioamnionitis and endometritis, bacteremia, and cesarean wound infection in the peripartum period. It was Pasteur who first identified microbes in the blood and lorchia of septic women. After that, in 1938 the isolation of S. agalactiae from three mortally ill women was reported, thereby implicating it as another cause of puerperal sepsis. S. agalactiae is now one of the most common causes of neonatal sepsis and meningitis in the United States. However, in Korea there have been only twenty-three cases of neonatal meningitis and/or sepsis due to group B β-hemolytic streptococcus reported. Recent studies have noted other serious infections in adults, including bacteremia, pneumonia, cellulitis, osteomyelitis, meningitis, and endocarditis. In Korean adults no case of pneumonia due to S. agalactiae has been reported till now. As minimal inhibitory concentration of penicillin was reported to be higher for S. agalactiae than for S. pyogenes, minimal inhibitory concentration of penicillin for S. agalactiae should be tested. Herein we describe the course of a case of S. agalactiae pneumonia and bacteremia in a 74-year-old diabetic man, and we review the literatures.
Adult*
;
Aged
;
Bacteremia
;
Cellulitis
;
Chorioamnionitis
;
Delivery of Health Care
;
Endocarditis
;
Endometritis
;
Female
;
Humans
;
Infant, Newborn
;
Korea
;
Meningitis
;
Osteomyelitis
;
Penicillins
;
Peripartum Period
;
Pneumonia*
;
Pregnancy
;
Sepsis
;
Streptococcus agalactiae*
;
Streptococcus*
;
United States
;
Urinary Tract Infections
;
Wound Infection
8.Plasma haloperidol, reduced haloperidol and homovanillic acid levels :therir relationship to therapeutic response of haloperidol in schizophtrenic patients.
Jong Inn WOO ; Jun Soo KWON ; Sang Ick LEE
Journal of Korean Neuropsychiatric Association 1992;31(3):443-456
No abstract available.
Haloperidol*
;
Homovanillic Acid*
;
Humans
;
Plasma*
9.A case of literature kluyvera sepsis in immunocompromised host.
Sun Ho CHANG ; Gyoo Rak LEE ; Jun Hee WOO
Korean Journal of Infectious Diseases 1991;23(2):113-115
No abstract available.
Immunocompromised Host*
;
Kluyvera*
;
Sepsis*
10.Effects of UV Light on DNA Synthesis Studied by Autoradiography.
Jai Il YOUN ; Jun Woo SHIN ; Yoo Shin LEE
Annals of Dermatology 1989;1(1):6-9
No abstract available.
Autoradiography*
;
DNA*
;
Ultraviolet Rays*