1.Current Scope and Perspective of Burden of Disease Study based on Health Related Quality of Life.
Seok Jun YOON ; Sang Cheol BAE
Journal of the Korean Medical Association 2004;47(7):600-602
No abstract available.
Quality of Life*
3.Detection of Hepatocelluar Carcinoma on Triple-Phase Images of Liver Using Multi-Detector Row Helical CT.
Ki Seok CHOO ; In Sook LEE ; Woong Bae JUN ; Yeon Joo JUNG ; Jun Woo LEE ; Seok Hong LEE
Journal of the Korean Radiological Society 2002;47(2):197-203
PURPOSE: To determine whether triple-phase multi-detector-row helical CT images of the liver improves the detection rate of hepatocellular carcinoma (HCC). MATERIALS AND METHODS: Forty-one patients with 103 HCCs underwent triple-phase multi-detector-row helical CT imaging of the entire liver after contrast administration. Early and late arterial phase images were obtained serially during a single breath-hold, and portal venous-phase images were then obtained. Each image set was independently assessed for the presence of HCC by two radiologists unaware of the possible presence of tumors, and for each phase the detection rate was determined. For each arterial-phase image, lesion conspicuity (attenuation of a tumor compared with that of its parenchyma) was calculated. RESULTS: For reader 1, the detection rates for the early arterial, late arterial, and portal venous phase were 81%, 77%, and 55%, respectively, and for reader 2 were 83%, 81%, and 68%, respectively (p>0.05). When triplephase imaging findings were combined, the detection rate was significantly higher than when only those of the early or late arterial, and portal venous, phase were used (p<0.05). Mean lesion conspicuity for the late arterial phase was higher than for the early arterial phase, but the difference was statistically insignificant (p>0.05). CONCLUSION: Triple-phase imaging of the liver, involving the early arterial, late arterial, and portal venous phase, and using multi-detector-row helical CT, increases the detection rate of HCC.
Carcinoma, Hepatocellular
;
Humans
;
Liver*
;
Tomography, Spiral Computed*
4.Comparison of Diagnostic and Therapeutic Efficacy between Ultrasound Guided Hydrostatic Saline Reduction and Fluoroscopic Barium Reduction in Children with Intussusception.
Chi Hyung PARK ; Ho Seok LEE ; Chong Woo BAE ; Sa Jun CHUNG ; Young Mook CHOI ; Sun Wha LEE ; Yup YUN
Journal of the Korean Pediatric Society 1995;38(12):1664-1670
No abstract available.
Barium*
;
Child*
;
Humans
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Intussusception*
;
Ultrasonography*
5.Adenovirus-Mediated Toxic Gene Therapy Using Cytosine Deaminase and Osteocalcin Promoter for the Treatment of Prostate Cancer.
Hong Seok PARK ; Jae Hyun BAE ; Du Geon MOON ; Hyun Yee CHO ; Chinghai KAO ; Thomas A GARDNER ; Jun CHEON
Korean Journal of Urology 2000;41(12):1437-1444
No abstract available.
Cytosine Deaminase*
;
Cytosine*
;
Genetic Therapy*
;
Osteocalcin*
;
Prostate*
;
Prostatic Neoplasms*
6.Comparison of Gastric Volume and Acidity between Children and Adults.
Kyung Un KIM ; Jun Seok BAE ; In Chan CHO ; Young Chul PARK
Korean Journal of Anesthesiology 2001;40(4):431-434
BACKGROUND: Aspiration of gastric contents into the lungs is one of the most feared complications during anesthesia. Various factors combine to make pediatric patients more susceptible to regurgitation and aspiration than adults. We compared the risk of incidence of acid aspiration in two groups, after examining the pH, and volume of gastric contents in pediatric and adult patients. METHODS: This study was carried out with inpatients scheduled for elective surgery under general anesthesia. Sixty patients from 1 to 13 years old were included in the pediatric age group, and sixty patients from 18 to 60 years old were included in the adult age group. After induction of anesthesia and stabilization of the condition of the patient, gastric contents were collected via a 10 - 18 French Salem Sump tube. Gastric volume and pH were measured. RESULTS: The mean gastric volume in the pediatric group was significantly higher than those in the adult group, whereas, The mean gastric pH in the adult group was significantly higher than those in the pediatric group. CONCLUSIONS: We concluded that pediatric patients have a lower gastric pH but a higher gastric volume than adult patients.
Adolescent
;
Adult*
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Anesthesia
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Anesthesia, General
;
Child*
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Humans
;
Hydrogen-Ion Concentration
;
Incidence
;
Inpatients
;
Lung
;
Middle Aged
7.The Effectiveness of Low Dose Fentanyl Bolus Injection in Cesarean Section after Umbilical Cord Clamping.
Jun Seok BAE ; Jong Nam LEE ; Young Chul PARK
Korean Journal of Anesthesiology 2003;45(2):200-204
BACKGROUND: For anesthesia in cesarean section N2O and low concentrations of inhalation anesthetics are regarded as the anesthetic agent of choice. But a low level of anesthesia frequently leads to increased maternal hemodynamic responses and awareness. The effects of a 3 microgram/kg fentanyl bolus injection after umbilical cord clamping was evaluated in 20 full-term parturients, scheduled for elective cesarean section, versus to 20 parturients without fentanyl. METHODS: The forty parturients (ASA physical status 1, 2) scheduled for cesarean section were randomized to either a N2O-enflurane (E group) or a N2O-enflurane-fentanyl (F group). Thiopental sodium (4 mg/kg) and succinylcholine (1.5 mg/kg) were administered intravenously for the induction and endotracheal intubation. Anesthesia was maintained with 50% N2O and 1% enflurane in oxygen until delivery. After delivery, the intravenous injection of 0.5 mg/kg of atracurium was administered, controlled ventilation was applied to maintain PetCO2 at 30 to 35 mmHg with N2O (3 L/min) and O2 (1.5 L/min). Immediately after clamping the umbilical cord, 3 microgram/kg of fentanyl (F group only) was administered. Heart rate, blood pressure, awareness, recovery time, postoperative complication and recall were evaluated. RESULTS: Heart rate values at 10 and 20 min after umbilical cord clamping and 5 min after extubation, and mean arterial pressure at 5, 10 and 20 min after umbilical cord clamping in group F were found to be significantly lower than in group E. CONCLUSIONS: We conclude that N2O-enflurane-fentanyl at 3 microgram/kg is clinically satisfactory in anesthesia for cesarean section, having no adverse effects on the mother.
Anesthesia
;
Anesthesia, General
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Anesthetics, Inhalation
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Arterial Pressure
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Atracurium
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Blood Pressure
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Cesarean Section*
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Constriction*
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Enflurane
;
Female
;
Fentanyl*
;
Heart Rate
;
Hemodynamics
;
Humans
;
Injections, Intravenous
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Intubation, Intratracheal
;
Mothers
;
Oxygen
;
Postoperative Complications
;
Pregnancy
;
Succinylcholine
;
Thiopental
;
Umbilical Cord*
;
Ventilation
8.Neuropathic Back Pain : Are There Any Practical Diagnostic Criteria?.
Kyeong Seok LEE ; Jae Jun SHIM ; Jae Won DOH ; Seok Mann YOON ; Hack Gun BAE ; Il Gyu YUN
Journal of Korean Neurosurgical Society 2007;41(1):65-68
OBJECTIVE: A new point of view on the chronic back pain proposed which is, named neuropathic back pain(NBP). Some proposed a certain pain scale as an useful diagnostic tool. Before scientific verification, some doctors prescribed a new anticonvulsant for the NBP. We investigated diagnostic tools for NBP by a review of the literature. METHODS: A comprehensive computer search of the English literature concerning neuropathic low back pain was performed using the key words such as neuropathic back pain and diagnosis in the PubMed. RESULTS: In 1998, the term NBP was first used in a patient with lung cancer. In the English literature, there were two diagnostic methods for the NBP, Neuropathic pain scale(NPS) and a pharmacological test. NPS is a pain questionnaire, which depends on the patients'subjective reports on the given questions, such as 'how hot is your pain feel'. By the pharmacological test, NBP was defined as 50% or more decrease of pain on intravenous lidocaine and on local anesthetic epidurally. It also depends on the patients'subjective response to the therapy. CONCLUSION: There were still no reliable objective diagnostic criteria for the NBP. It seems to be better to reserve the new anticonvulsants for the NBP till scientific approval.
Anticonvulsants
;
Back Pain*
;
Diagnosis
;
Humans
;
Lidocaine
;
Low Back Pain
;
Lung Neoplasms
;
Neuralgia
;
Pain Measurement
;
Surveys and Questionnaires
9.Sonographic Findings of Coccygeal Abscess in the Neonates.
Jun Gi BAE ; Ji Hye KIM ; Seok CHUN ; Young Seok LEE ; Hyung Sik KIM ; Sang Hi KIM
Journal of the Korean Radiological Society 1998;38(3):535-538
PURPOSE: The purpose of this study was to report the sonographic findings of neonatal coccygeal abscess,previously not described. MATERIALS AND METHODS: Eighteen neonates (5-18 days old) presented with swelling in thecoccygeal area and by either open drainage (n=13) or follow-up after antibiotic therapy (n=5), this was diagnosedas coccygeal abscess. We retrospectively reviewed the size, shape, location, echo pattern and marginalcharacteristics of the abscesses, as seen on sonography, as well as their intradural content and relationship withthe spine. Additional MR images (n=5) were separately reviewed. RESULTS: Mean longest diameter of the abscesseswas 1.5cm (range, 0.8-2.3); they were oval or round and located in the subcutaneous fat layer. Echogenicitycompared with surrounding fat varied: in nine patients it was isoechoic, and in nine, hypoechoic. Internalechogenicity was homogenous in 14 patients and heterogeneous in four, and in seven cases, the margin of theabscess was well demarcated. Intradural structure and bony spines were normal, and the possibility of spinaldysraphism, could thus be excluded. All cases except one were correctly diagnosed by sonography and clinicalfindings; on sonography, the echogenicity of one lesion was exactly the same as that of lipoma, and it was thusmisdiagnosed. In cases where sonography revealed an isoechoic mass, the use of MR excluded the possibility oflipoma. Three of five cases showed marginal or diffuse enhancement on contrast enhanced MR images. CONCLUSION: Coccygeal absesses were confined to the subcutaneous fat layer and were either iso- or hypoechoic compared. withsurrounding fat. In neonates, abscess formation in the coccygeal area is possible, and coccygeal abscess shouldtherefore be included in the differentiation of coccygeal masses.
Abscess*
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Coccyx
;
Drainage
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Follow-Up Studies
;
Humans
;
Infant, Newborn*
;
Lipoma
;
Retrospective Studies
;
Spine
;
Subcutaneous Fat
;
Ultrasonography*
10.Multiple Densities of the Chronic Subdural Hematoma in CT Scans.
Hye Ran PARK ; Kyeong Seok LEE ; Jae Jun SHIM ; Seok Mann YOON ; Hack Gun BAE ; Jae Won DOH
Journal of Korean Neurosurgical Society 2013;54(1):38-41
OBJECTIVE: Density of the chronic subdural hematoma (cSDH) is variable. It often appears to be mixed density. Multiple densities of cSDH may result from multiple episodes of trauma. We investigated the frequency of mixed density and the causes of head injuries representing each density. METHODS: We could collect 242 cases of chronic SDH. The cSDHs were classified into four groups; hypodensity, homogeneous isodensity, layered type, and mixed type on the basis of CT scans. RESULTS: The density of cSDH was isodense in 115 patients, hypodense in 31 patients, mixed in 79 cases, and layered in 17 cases. The cSDH was on the left side in 115 patients, on the right side in 70 patients, and bilateral in 40 patients. The history of trauma was identifiable in 122 patients. The etiology could be identified in 67.7% of the hypodense hematomas, while it was obscure in 59.5% of the mixed hematomas. CONCLUSION: Mixed density of cSDH results from multiple episodes of trauma, usually in the aged. It is hard to remember all the trivial traumas for the patients with the mixed density cSDHs. Although there were membranes within the mixed density hematomas, burr-holes were usually enough to drain the hematomas.
Aged
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Craniocerebral Trauma
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Hematoma
;
Hematoma, Subdural, Chronic
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Humans