1.Present status and future of hospice palliative care in Korea.
Korean Journal of Medicine 2004;67(4):327-329
No abstract available.
Hospices*
;
Korea*
;
Palliative Care*
2.Differential Diagnosis of Lymphadenopathy.
Journal of the Korean Medical Association 2000;43(10):1001-1008
No abstract available.
Diagnosis, Differential*
;
Lymphatic Diseases*
3.Institutionalization of Hospice.
Journal of the Korean Medical Association 1998;41(11):1141-1146
No abstract available.
Hospices*
;
Institutionalization*
4.Expression of type IV collagen and laminin genes by skin fibroblasts in culture.
Korean Journal of Dermatology 1992;30(3):317-324
Basement membrane zone gene expression by fibroblast cultures was examined by molecular hybridizations with human sequence specific cDNAs corresponding to type 1V procollagen and laminin subunit polypeptides. Northern transfer analysis with total RNA revealed the presence of specific mRNA transcripts for al (IV) and a2 (1V) chains of type 1V procollagen as well as Bl and B2 chains of laminin. Laminin A chain mRNAs were not detected using the same RNA preparations. The molecular size of al (1V) and a2 (1V) procollagen mRNA revealed 6.8kb and 6.7kb, respectively. The molecular size of Bl chain of laminin revealed 5.6kb, and B2 chain revealed 8.2 and 5.5kb polymorphic transcripts. In slotblot analysis using densitometer, steady-state levels of type IV procollagen and laminin mRNAs indicated that they were in relatively low abunclance, as compaired with type I procollagen mRNA. Quantitative levels of al (IV) and laminin Bl chaii mRNAs were more abundant than those of a2 (IV) and laminin B2 mRNAs. The mRNA ratio of al (IV)/a2 (lV) and laminin Bl/B2 were 1.9 and 1.5, respectively. These results demonstrate evidence for differential regulation of the expression of different basement membrane zone molecules during the formation of basement membrane.
Basement Membrane
;
Collagen Type I
;
Collagen Type IV*
;
DNA, Complementary
;
Fibroblasts*
;
Gene Expression
;
Humans
;
Laminin*
;
Peptides
;
Procollagen
;
RNA
;
RNA, Messenger
;
Skin*
5.Prevalence of antibodies to hepatitis C virus in hemodialysis patients.
Jun SUK ; Il JOO ; Gye Cheol KWON
Korean Journal of Nephrology 1992;11(4):437-440
No abstract available.
Antibodies*
;
Hepacivirus*
;
Hepatitis C*
;
Hepatitis*
;
Humans
;
Prevalence*
;
Renal Dialysis*
6.Studies on Platelet Aggregability in Thrombotic Disease and Hypercholesterolemia and Effects of Aspirin and Dipyridamole.
Korean Circulation Journal 1985;15(3):421-440
Although platelet have been implicated in the pathogenesis of the thrombotic disease, the platelet aggregability was not well studied in Korea. Author measured platelet aggregability in 103 clinical cases including 30 healthy volunteers to evaluate the platelet function and the effect of Aspirin and Dipyridamole on aggregability in Korean. 24 patients with cerebral thrombosis, 24 patients with ischemic heart disease and 25 patients with hypercholesterolemia were included for this study. Aggregation tests were performed at three final concentrations of epinephrine(10microM/L) and ADP(4 microM/L, 10 microM/L) with platelet aggregometer which was made by Chrono-Log Corp. in all cases. Platelet aggregations were measured in patients who were treated with Aspirin, Dipyridamole and combined treatment of Aspirin and Dipyridamole respectively. The following results were obtained. 1) The mean maximal platelet aggregability in the normal subjects induced by 10 microM/L epinephrine was 59.3+/-24.26%, 66.6+/-14.00% in Bm and 62.5+/-19.30% in B5 in induction by 4 microM/L ADP, and 77.2+/-8.99% in Bm and 76.6+/-9.83% in B5 in induction by 10microM/L ADP. 2) The mean maximal platelet aggregability in patients with cerebral thrombosis induced by 10 microM/L epinephrine was 89.2+/-7.33%, 78.8+/-9.41% in Bm and 78.5+/-9.93% in B5 in induction by 4 microM/L ADP, and 86.4+/-7.69% in Bm and B5 in induction by 10 microM/L ADP. The results showed significantly elevated platelet aggergability than that of normal subjects(p<0.01). 3) The mean maximal platelet aggregability in patients with ischemic heart disease induced by 10 microM/L epinephrine was 88.1+/-11.99%, 78.2+/-12.50% in Bm and B5 in induction by 10 microM/L ADP. The results showed significantly elevated platelet aggregability than that of normal subjects(P<0.01). 4) The mean maximal platelet aggregability in patients with hypercholesterolemia induced by 10 microM/L epinephrine was 86.8+/-15.99%, 82.7+/-11.19% in Bm and 82.0+/-12.87% in B5 in induction by 4 microM/L ADP, and 88.5+/-11.47% in Bm and B5 in induction by 10 microM/L ADP. The results showed signifcantly elevated platelet aggregability than that of normal subjects(P<0.01). 5) The mean maximal platelet aggregability in patients with thrombotic disease was studied by Dipyridamole administration. The platelet aggregability induced by epinephrine before administration was 90.9+/- 8.52% and after administration it was 78.9+/-15.68%, and the results showed that Dipyidamole lowered aggregability significantly. The platelet aggregability induced by 4 microM/L ADP before administration was 84.0+/-11.90% in Bm and B5 and after administration it was 78.0+/-11.44% in Bm and B5, and the results showed that Dipyridamole lowered aggregability but not significant. The platelet aggregability induced by 10 microM/L ADP before administration was 89.2+/-10.39% in Bm and B5 and after administration it was 80.5+/-8.44% in Bm and B5, and the results showed that Dipyridamole lowered aggregability significantly. 6) The mean maximal platelet aggregability in patients with thrombotic disease was studied by Aspirin administration. The platelet aggregability induced by epinephrine before administration was 91.0+/-4.79% and after administration it was 47.6+/-17.72%. The platelet aggregability induced by 4 microM/L ADP before administration was 84.6+/-10.37% in Bm and B5 and after administration it was 72.6+/-11.85% in Bm and 65.3+/-15.97% in B5. The platelet aggregability induced by 10 microM/L ADP before administration was 84.9+/-6.30% in Bm and B5 and after adminstration it was 77.7+/-8.60% in Bm and 75.0+/-8.89%. The results showed that Aspirin lowered aggregability markedly. 7) The mean maximal platelet aggregability in patients with thrombotic disease was studied by combined administration of Aspirin and Dipyridamole. The platelet aggregability induced by epinephrine before administration was 86.7+/-13.77% and after administration it was 36.7+/-14.01%. The platelet aggregability induced by 4 microM/L ADP before administration was 81.5+/-12.93% in Bm and 80.6+/-14.15% in B5 amd after administration it was 54.7+/-17.27% in Bm and 44.6+/-21.17% in B5. The platelet aggregability induced by 10 microM/L ADP before administration was 87.8+/-10.11% in Bm and B5 and after administration it was 65.7+/-13.59% in Bm and 62.0+/-16.42% in B5. The results showed that combined administration of Aspirin and Dipyridamole lowered aggregability significantly and the results were lower than that of normal subjects. 8) The effects of combined treatment of Aspirin and Dipyridamole showed marked reduction of platelet aggregability than that of single treatment of Aspirin or Dipyridamole in thrombotic disease.
Adenosine Diphosphate
;
Aspirin*
;
Blood Platelets*
;
Dipyridamole*
;
Epinephrine
;
Healthy Volunteers
;
Humans
;
Hypercholesterolemia*
;
Intracranial Thrombosis
;
Korea
;
Myocardial Ischemia
7.A clinical study of supracondylar closing wedge osteotomy for cubitus varus.
Seok Hyun LEE ; Jae Suk CHANG ; Hong Chul SIN ; Jun Suk HONG
The Journal of the Korean Orthopaedic Association 1993;28(1):240-246
No abstract available.
Osteotomy*
8.The Cytologic Features of Desmoplastic Small Round Cell Tumor with Intranuclear Inclusions : A Case Report .
Ho Chang LEE ; Hye Suk HAN ; Ok Jun LEE
Korean Journal of Pathology 2009;43(3):279-284
Desmoplastic small round cell tumor (DSRCT) is a rare neoplasm of young adults and it is characterized by polyphenotypic differentiation. We experienced a case of abdominal DSRCT that occurred in a 19-year-old female who presented with painful swelling of her right forearm. The tumor was cytokeratin-negative and it exhibited some tumor cells with intranuclear inclusions. Molecular demonstration of EWS-WT1 fusion transcripts is particularly useful to confirm the diagnosis of DSRCT without epithelial differentiation. We report here on a case of cytokeratin-negative DSRCT that showed an unusual feature of intranuclear inclusions.
Desmoplastic Small Round Cell Tumor
;
Female
;
Forearm
;
Humans
;
Intranuclear Inclusion Bodies
;
Keratins
;
Young Adult
9.Surgical management of congenital muscular torticolis: with family history.
Byung Chae CHO ; Jun Suk BYUN ; Bong Soo BAIK
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1991;18(3):475-485
No abstract available.
Humans
10.Induction of preneoplastic lesion in the large intestine of rats by oral administration of 2-amino-1-methyl-6-phenylimidazo4,5-bpyridine.
Yong Suk KIM ; Kwang Soo LEE ; Kye Young JUN
Journal of the Korean Society of Coloproctology 1993;9(2):125-130
No abstract available.
Administration, Oral*
;
Animals
;
Intestine, Large*
;
Rats*