Objective To investigate the effect of endovascular interventional therapy on intracranial aneurysm.Methods We retrospectively analyzed the clinical information and treatment efficacy of 48 patients (53 aneurysms) experienced interventional embolism therapy; these patients were admitted to and received treatment in our hospital from January 2001 to December 2009.Results Among the 53 aneurysms of 48 patients,40 aneurysms were obliterated completely,6 aneurysms 95％ obliterated,5 aneurysms 90％ obliterated and 2 aneurysms failed; 2 aneurysms ruptured and no death was noted during the operation.Six to 12 months after the operation,follow-up of the 46 patients indicated that 2 were recurred under CMA or DSA; 2 was severely disabled; 5 had mild neurological deficits; and the other enjoyed good results.Conclusion Endovascular embolization ofaneurysms is a minimally invasive method with low risk; individualized embolism therapy can improve the prognosis.