Numerous drugs are known to cause seizures with therapeutic use or overdose. However, the relative frequency of such complications has rarely been studied, and little is known about the relationship of drug-induced seizures to eventual medical outcome. This study was performed to determine the causes and consequences of seizure associated with poisoning and drug intoxication. We analyzed about 786 cases of drug intoxication visited to Chung-Ang Gil hospital during recent 4 years from Jan. 1993 to Dec. 1996. The results were summarized as follows: 1. The total number of cases of drug intoxication was 786 and the most common drug of intoxication was antihistamines(291 cases, 36.3%); insecticides(113 cases, 14.7%); caustics(90 cases, 11.8%); herbicides(47 cases, 6.1%); NSAID(38 cases, 4.9%); rodenticides(36 cases, 4.6%); acetaminophens(34 cases, 4.4%); anticonvulsants(18 cses, 2.3%); neuroleptics(13 cases, 1.6%); hydrocarbons(9 cases, 1.2%); sympathomimetics(8 cases, 1.0%). 2. The leading causes of seizures were antihistamines(12 cases, 42.8%); insecticides(7 cases, 25.0%); sympathomimetics(3cases, 10.7%); neuroleptics(2 cases, 7.2%); others(4 cases, 14.3%). 3. Seizures associated with antihistamines were generally brief(11 cases, 92.0%) and uncomplicated(3 cases, 25.0%). 4. Seizures incidence by drug intoxication was relatively high in sympathomimetics(3 cases, 35.7%); and neuroleptics(2 cases, 15.4%). 5. Poisoning associated with seizure had relatively high risk compared with non seizure poisoning for medical complication.
Drug Overdose* ; Histamine Antagonists ; Incidence ; Poisoning* ; Seizures*

No abstract available.
Crowns* ; Glass*

Acrylonitrile is most commonly used aliphatic nitrile compounds characterized by the structural formula R-C=N and used mossy to make acrylic fibers, plastics, synthetic rubber, and wall coverings. In recent, because of its extensive usage and the rapid expansion of the chemical industry, many poisonings have been reported and many studies on its health effects have been performed. Acute toxicity resembles cyanide poisoning and results mainly in effects on the nervous system. High exposure also can cause temporary damage to red blood cells and the liver and can cause lead to death. Because long-term occupational exposure to the acrylonitrile has been with cancer in humans, the U.S EPA classifies acrylonitrile as probable carcinogen. For this reason, The federal government has developed regulations and advisories to protect individuals firm the potential health effects of acylonitrile in the environment, but there are few studies, case reports and regulations of the government in our country. We experienced acute poisoning caused by acrylonitrile inhalation that occurred in an industrial accident. So, we report this case with literature reveiw.
Accidents, Occupational ; Acrylonitrile* ; Chemical Industry ; Elastomers ; Erythrocytes ; Federal Government ; Humans ; Inhalation* ; Liver ; Nervous System ; Occupational Exposure ; Plastics ; Poisoning* ; Social Control, Formal

No abstract available.
Emergencies* ; Emergency Service, Hospital*

A retrospective review was performed of 297 patients admitted to Chung Ang Gil Hospital between June 1995 and December 1996 with a diagnosis of blunt chest trauma. Of these patients, 34% suffered either immediate or delayed complications. Immediate complications included hemothorax in 58.8%, pneumothorax in 26.5%, and pulmonary contusion in 20.5%. Delayed complications occurred in 9.1% of patients overall; these included pulmonary contusion in 12.7%, pneumonia in 9.8%, pulmonary embolism in 2%, poeumothorax in 2%, and hemothorax in 2%. The mean age of the patients were 43 years. 210 patients(70.7%) were under age 50 and 87(29.3%) were 50 years of age or older. Male to female ratio was 1.9:1. Mean Initial Revised Trauma Score (RTS) and the Injury Severity Score (ISS) were 7.10+/-0.94 and 14+/-8.69, respectively. There were associated injuries in 225(75.8%) patients. Overall mortality rate was 7.1% and the mortality rate was significantly greater in patients with a RTS<6, ISS>or=16, associated injuries, advanced age(50 years of age or older), and pulmonary complications. Pulmonary complications were significantly greater in patients with a RTS<6, ISS>or=16, and an associated injuries.
Contusions ; Diagnosis ; Female ; Hemothorax ; Humans ; Injury Severity Score ; Male ; Mortality* ; Pneumonia ; Pneumothorax ; Pulmonary Embolism ; Retrospective Studies ; Thorax*

We report two cases of extramammary Paget's disease associated with ad enocarcinoma with metascases. Histologically, Iaget cells in the epidermis and the hair follicles and adenocarcinoma in the der mis was observed in both cases. Of special interest was the demonstration of Eaget cells extending from the involved epidermis to the underlying dermis in case 2, There were metastatic lesioris of 3rd lumbar vertebra in case 1 and of the liver and lymph nodes in rase 2.
Adenocarcinoma* ; Dermis ; Epidermis ; Hair Follicle ; Liver ; Lymph Nodes ; Neoplasm Metastasis* ; Paget Disease, Extramammary* ; Spine

PURPOSE: To report clinical appearances and the outcomes of patients treated for wrist laceration with suicidal intent. MATERIALS AND METHODS: Between March 2005 and February 2008, patients with wrist laceration were treated at our center. Among them, 14 patients with suicidal intent were reviewed retrospectively. They were 8 females and 6 males with a mean age of 33 years at the time of treatment. The side of injured wrist, injured structures, suicidal instrument, the time of injury, a suicidal motive, drug or alcohol abuse or not, indication of combined psychiatric disease, the duration of postoperative treatment, and the results of treatment were analyzed. RESULTS: The injured wrist was the left one in 13 cases (93%), and knife wounds in 11 cases (79%) was the most frequent mechanism of injury. An average of 4.6 structures were injured including 3.5 tendons, 0.57 nerves and 0.5 arteries. The most frequently injured structures were the palmaris longus (71%), FCU (50%), FCR (43%), FDS 3 (36%), FDS 2, median nerve, and ulnar artery (each 29%). Simultaneous injury of both median and ulnar nerves occurred in 3 cases (21%), and simultaneous injury of both radial and ulnar artery occurred in 1 case (7%). The injury time was the night in 12 cases (86%), and the most frequent suicidal motive was human relations such as lover or spouse in 12 cases (86%). In 9 cases (64%), the injured were in a drunken state, 3 cases (21%) had been treated for a psychiatric disease at the time of the injury. The durations of postoperative treatment were an average of 5 days of admission and 1 day follow up. Only 1 case results could be evaluated. CONCLUSIONS: Patient's poor compliance in wrist laceration with suicidal intent should be expected and these characteristics may affect the management plan.
Alcoholism ; Arteries ; Compliance ; Female ; Follow-Up Studies ; Humans ; Lacerations ; Male ; Median Nerve ; Retrospective Studies ; Spouses ; Suicide ; Tendons ; Ulnar Artery ; Ulnar Nerve ; Wrist

Congenital Abnormalities ; Female ; Humans ; Jaw ; Jeollabuk-do ; Male ; Orthognathic Surgery ; Osteotomy ; Osteotomy, Sagittal Split Ramus ; Rehabilitation ; Surgery, Oral

No abstract available.
Gangwon-do* ; Hepacivirus* ; Hepatitis C* ; Hepatitis* ; Liver Diseases* ; Liver* ; Prevalence*

No abstract available.