No abstract available.
Internet*

No abstract available.
Hand Disinfection*

No abstract available.

No abstract available.
Critical Care* ; Humans ; Intensive Care Units*

No abstract available.

Among the efficient cancer treatments, photodynamic therapy (PDT) is one of the therapies inducing rapid apoptosis of cancer cells while causing minimal damage to surrounding normal tissue. We studied the effect of PDT on the adenocarcinoma in BALB/-c mice of homograft model, and the following results were obtained. Apoptosis occurred up to 3 mm in depth from the surface in the first 1 hour after PDT applied, and subsequently the counts were increased in the deeper portion. A remarkable apoptosis observed up to 6 mm in depth shows that the light in use could not penetrate more than 6 mm of tissue. Tissue necrosis was identified in the deeper area of the tumor 6 hours later or thereafter. This necrosis seemed to occur as an indirect effect of vascular obstruction resulting from the damage of endothelial cells which was induced by selective collection of photosensitizer in the endothelial cells of newly forming vessels as well as in the cancer cells. These results indicate that the effective depth of PDT is greater than the depth of light penetration.
Adenocarcinoma* ; Allografts* ; Animals ; Apoptosis ; Endothelial Cells ; Mice* ; Necrosis ; Photochemotherapy*

No abstract available.

No abstract available.

No abstract available.
Antibodies* ; Hepacivirus* ; Hepatitis C* ; Hepatitis* ; Humans ; Prevalence* ; Renal Dialysis*

Juvenile rheumatoid arthritis is basically the same disease as rheumatoid arthritis in the adult. However juvenile rheumatoid arthritis has many features that differ from rheumatoid arthritis in adult, and since the onset of the disease occurs before the age of puberty variable alteration in growth may occur. Still, in his classic description of 22 cases of rheumatoid arthritis in children, emphasized the florid form of the disease with fever, lymphadenopathy, and splenomegaly. Since the time of Still many more children with chronic arthriits, which is called Stills disease in England and juvenile rheumatoid arthritis in the United States, have been described, and it has become apparent that the disease has extremely variable manifestations. Forty cases of juvenile rheumatoid arthritis treated at the Severance Hospital from June 1970 to June 1976 were analysed clinically and the following results were obtained. 1. On type classification, the polyarticular type (45%) was most frequent followed by the pauciarticular type (35%) and systemic type (20%) in order. 2. The most frequent joint affected was the knee (77.5%) followed by the ankle (55%), wrist (20%),. elbow (17.5%), etc. 3. The extra-articular manifectations on admission were high fever (42%), rash (20%), carditis (17%) hepatosplenomegaly (12%), etc. 4. Laboratory findings on admission showed increased ESR (85%), positive rheumatoid factor (14.3%),. positive ANA (2.5%), etc. 5. Treatment and drugs were aspirin (57.5%), salicylate and steroid (37.5%), physical therapy (25%), synovectomy (2.5%).
Adolescent ; Adult ; Ankle ; Arthritis, Juvenile ; Arthritis, Rheumatoid ; Aspirin ; Child ; Classification ; Elbow ; England ; Exanthema ; Fever ; Humans ; Joints ; Knee ; Lymphatic Diseases ; Myocarditis ; Puberty ; Rheumatoid Factor ; Splenomegaly ; United States ; Wrist