1.An Analysis of Histopathologic Evaluation of Lung Carcinomas in Last Ten Years.
Ji Min JEON ; Sun Young KWON ; Eun Sook CHANG ; Young Jun JEON ; Kun Young KWON
Korean Journal of Pathology 1999;33(7):483-489
Lung cancer is one of the most common types of malignancy in western nations with serious health problem, and it has become the leading cause of cancer death of males, second only to stomach cancer, in Korea. A review of the histopathology of 1363 cases (1231 patients) of lung carcinoma, diagnosed at the Keimyung University Medical center from 1987 to 1996, was performed to reclassify the type of carcinomas and to investigate the change in the distribution of histologic types of lung carcinoma according to age, sex and year. Among the 1363 cases, 132 patients underwent a surgical operation after biopsy. The diagnosis of each case was proven by histopathologic analysis of surgical specimens (13.2%) and biopsy materials (86.8%). The histologic types in our study were basically based on modified WHO classification (1982) and on new WHO classification (1999). The classification of small cell carcinoma was based on International Association for the Small Cell Lung Cancer (IASLC, 1988). Of the 1231 patients with lung carcinoma, 1012 were male and 219 were female (male to female ratio was 3.6:1). According to the analysis of age distribution, the most prevalent age group was 60~69 years in both sex as (n=516, 42.0%). Changing trends in sex distribution of lung carcinoma patients showed that the proportion of men had decreased throughout the years, whereas the proportion of women had significantly increased. Histologically, squamous cell carcinoma was the most common (n=624, 50.7%), followed by small cell carcinoma (21.1%), adenocarcinoma (18.1%), large cell undifferentiated carcinoma (2.1%), adenosquamous carcinoma (0.4%), and large cell neuroendocrine carcinoma (0.4%), in order of frequency. In men, squamous cell carcinoma was the most frequent type (55.1%). In women, adenocarcinoma was the most frequent type (39.7%). In both sexes, adenocarcinoma was the most common type in patients under the age of 40 (n=12, 41.4%), while squamous cell carcinoma proved the most frequent type in patients over the age of 40 (n=617, 51.3%). Changing trends of histologic types of lung cancer showed that the incidences of squamous cell carcinoma had significantly decreased throughout the years, whereas those of adenocarcinoma and small cell carcinoma had increased. In conclusion, the results showing increases in the percentage of female patients and in the number of cases of adenocarcinoma were noteworthy, and well correlated with other related reports.
Academic Medical Centers
;
Adenocarcinoma
;
Age Distribution
;
Biopsy
;
Carcinoma
;
Carcinoma, Adenosquamous
;
Carcinoma, Neuroendocrine
;
Carcinoma, Small Cell
;
Carcinoma, Squamous Cell
;
Classification
;
Diagnosis
;
Female
;
Humans
;
Incidence
;
Korea
;
Lung Neoplasms
;
Lung*
;
Male
;
Sex Distribution
;
Small Cell Lung Carcinoma
;
Stomach Neoplasms
2.Immunohistochemical studies on neuroendocrine cell changes in disease of uterine cervix.
Sei Jun HAN ; Kyung Sig CHANG ; Ho Jong JEON
Korean Journal of Obstetrics and Gynecology 1992;35(8):1144-1153
No abstract available.
Cervix Uteri*
;
Female
;
Neuroendocrine Cells*
3.Arthritis as a cause of open bite.
Choong Kook YI ; Soo Won CHOI ; Jun Hong JEON
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1992;18(4):73-80
No abstract available.
Arthritis*
;
Open Bite*
4.A Case of Bilateral Wilms' Tumor.
Hyun Jun CHO ; In Sang JEON ; Hyo Seop AHN ; Hwang CHOI
Journal of the Korean Pediatric Society 1990;33(1):117-123
No abstract available.
Wilms Tumor*
5.Two Cases of Generalized Granuloma Annulare.
Ki Hong KIM ; Ui Sik JEON ; Jae Bok JUN
Korean Journal of Dermatology 1974;12(4):281-284
Two cases with generalized G.A. were described. The first case was 42 years, old farmer representing slightly erythematous multiple papulonodular lesions on the face, neck, scapular areas, arms and dorsal hands. Coalescence of lesions in some areas of the dorsal hands and neck produced circinate or polycyclic pattern. The second case was 4 years old girl who developed purple to brown muliple papulonodular lesions and polygonal or round plague on the arms, dorsal hands, palms, neck, iliac crests, lower legs, dorsal feet and sole. The plague lesions mimick lichen planus.
Arm
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Child, Preschool
;
Female
;
Foot
;
Granuloma Annulare*
;
Granuloma*
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Hand
;
Humans
;
Leg
;
Lichen Planus
;
Neck
;
Plague
6.Changes in the Eradication Rate of Conventional Triple Therapy for Helicobacter pylori Infection in Korea.
The Korean Journal of Gastroenterology 2014;63(3):141-145
Although, the prevalence of Helicobacter pylori infection in Korea has declined owing to the eradication therapy, recent seroprevalence of H. pylori infection is still reported to be as high as 54.4%. Until now, "standard regimen" for eradication of H. pylori has been conventional triple therapy consisting of proton pump inhibitor, amoxicillin, and clarithromycin. However, with the increase in antibiotic resistance, especially against clarithromycin, the eradication rate of conventional triple therapy has steadily declined during the past 13 years in Korea. Present eradication rate of standard triple therapy is reported to be less than 80%, which is the Maginot line of efficacy for the currently available regimen. Therefore, new first line eradication regimen is needed to enhance the eradication rate of H. pylori infection.
Amoxicillin/pharmacology/therapeutic use
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Anti-Bacterial Agents/pharmacology/*therapeutic use
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Asian Continental Ancestry Group
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Clarithromycin/pharmacology/therapeutic use
;
Disease Eradication/trends
;
Drug Administration Schedule
;
Drug Therapy, Combination
;
Helicobacter Infections/*drug therapy
;
*Helicobacter pylori/drug effects
;
Humans
;
Proton Pump Inhibitors/therapeutic use
;
Republic of Korea
7.A Case of Subcutaneous Fat Necrosis of the Newborn.
Hong Shin JEON ; Myung Ik LEE ; Don Hee AHN ; Hee Jun YOO
Journal of the Korean Pediatric Society 1994;37(3):405-409
A 7 day old female baby suffered from perinatal asphyxia and trauma at birth. Subsequently, she had a violeceous subcutaneous plaque on back. The clinical setting, the skin manifestation and the histologic findings of the lesion were diagnostic of subcutaneous fat necrosis of the newborn. Histologic findings revealed fat necrosis with infiltration of inflammatory cells, foreign body giant cells and several fat cells contain needle shaped cleft in radial arrangement. Four weeks latter, the skin lesion was healed spontaneously.
Adipocytes
;
Asphyxia
;
Fat Necrosis
;
Female
;
Giant Cells, Foreign-Body
;
Humans
;
Infant, Newborn*
;
Necrosis*
;
Needles
;
Parturition
;
Skin
;
Skin Manifestations
;
Subcutaneous Fat*
8.Preventive Effect of Lidocaine Pretreatment and Tourniquet Use on Propofol Injection Pain.
Korean Journal of Anesthesiology 2001;41(5):543-548
BACKGROUND: Pain on injection of propofol is a common problem, the cause of which remains unKnown. We evaluated the optimum time of a tourniquet with intravenous lidocaine, to decrease the intensity of pain during intravenous propofol injection. METHODS: In 72 patients undergoing general anesthesia, we subdivided all patients into 4 groups. Patients in group 1 (n = 18) received propofol only (1 mg/Kg IV) without a tourniquet, patients in group 2 (n = 18) received 1% lidocaine 20 mg IV with an upper arm tourniquet inflated to 50 mmHg applied for 1 minute followed by propofol (1 mg/Kg IV). We applied a tourniquet to patients in group 3 (n = 18) and 4 (n = 18) for 3 minutes and 5 minutes respectively. The intensity of pain along the forearm was classified in 4 degrees (none, mild, moderate, severe) by the patients and the observer simultaneously. The mean arterial pressure and heart rate were recorded before injection and at the time when the patient complained of pain. RESULTS: All groups were similar in age, sex, weight and height. The group with the tourniquet applied for 5 minutes followed by a lidocaine injection showed the lowest intensity of pain. However, between the group with 3 minutes and 5 minutes, the difference of the pain score was not statistically significant. CONCLUSIONS: We conclude that intravenous lidocaine administered after a tourniquet has been inflated to 50 mmHg for 3 minutes before propofol injection attenuates profoundly the pain associated with intravenous propofol injection.
Anesthesia, General
;
Arm
;
Arterial Pressure
;
Forearm
;
Heart Rate
;
Humans
;
Lidocaine*
;
Propofol*
;
Tourniquets*
9.Objective Optical Quality Analysis in Dry Eye Syndrome.
Journal of the Korean Ophthalmological Society 2014;55(11):1600-1605
PURPOSE: To evaluate the efficacy of Optical Quality Analysis System (OQAS(R)) instrument for the assessment of dry eye syndrome. METHODS: Dynamic recording of double-pass (DP) retinal images was performed in 1 eye dry eye patients (20 eyes) and in healthy controls (20 eyes) for 20 seconds after eye blinking. RESULTS: The mean objective scatter Index (OSI) value was 4.53 in dry eyes, 0.67 in healthy eyes and the standard deviation of OSI was 1.20 in dry eyes and 1.18 in healthy eyes. The patients with dry eyes showed significantly higher mean OSI and standard deviation values. Ocular scatter increased over time and significant changes occurred 13.5 seconds after blinking. The difference in OSI value between 0 second and 20 seconds was significantly greater in dry eye patients (4.15) than in controls (0.32). CONCLUSIONS: Ocular scatter increased over time after blinking. The dry eye patients had larger and more variable ocular scatter index than the controls. OQAS(R) may be useful to detect and follow-up tear film-related patient complaints in dry eye syndrome.
Blinking
;
Dry Eye Syndromes*
;
Humans
;
Retinaldehyde
;
Tears
10.A Case of Congenital Long OT Syndrome with Pseudo - Atrioventricular Block.
Kyoung Hi JEON ; Yong Woon BACK ; Hyun Kee CHUNG ; Tae Jun CHA ; Sung Rae CHO
Journal of the Korean Society of Neonatology 1999;6(2):263-267
The congenital long-QT syndrome (LQTS) is characterized by recurrent syncope, prolonged QT intervals, QT interval lability, polymorphic ventricular tachycardia, and sudden death. We report a case of congenital long QT syndrome in a 28-day-old male infant who presented with syncope, bradycardia with 2: 1 pseudo-atrioventricular block and a markedly prolonged QT inteval. One episode occured after crying and degenerated into ventricular fibrillation and terminated after cardioversion. A VVI type cardiac pacemaker was implanted. Subsequently, the infant's heart rate was over 110/min and 2: 1 AV block and any other arrhythmia were absent. The infant recovered from the accompanied pneumonia and sepsis and was discharged 47 days after adrnission. However, 13 days after discharge, the infant returned to our hospital ER with syncope. Ventricular fibrillation ceased after cardioversion. Despite medication with propranolol, ventricular tachycardia persisted. The infant expired the day after he was discharged against medical advice.
Arrhythmias, Cardiac
;
Atrioventricular Block*
;
Bradycardia
;
Crying
;
Death, Sudden
;
Electric Countershock
;
Heart Rate
;
Hospitals
;
Humans
;
Infant
;
Long QT Syndrome
;
Male
;
Pneumonia
;
Propranolol
;
Sepsis
;
Syncope
;
Tachycardia, Ventricular
;
Ventricular Fibrillation