1.Recurrent Aspiration Pneumonia due to Anterior Cervical Osteophyte.
Jae Jun LEE ; Ji Young HONG ; Jun Han JUNG ; Jun Hyeok YANG ; Jun Young SOHN
Korean Journal of Critical Care Medicine 2017;32(1):74-78
A 74-year-old man presented with recurrent vomiting and aspiration pneumonia in the left lower lobe. He entered the intensive care unit to manage the pneumonia and septic shock. Although a percutaneous endoscopic gastrostomy tube was implanted for recurrent vomiting, vomiting and aspiration recurred frequently during admission. Subsequently, he complained of neck pain when in an upright position. A videofluoroscopic swallowing study showed compression of the esophagus by cervical osteophytes and tracheal aspiration caused by an abnormality at the laryngeal inlet. Cervical spine X-rays and computed tomography showed anterior cervical osteophytes at the C3-6 levels. Surgical decompression was scheduled, but was cancelled due to his frailty. Unfortunately, further recurrent vomiting and aspiration resulted in respiratory arrest leading to hypoxic brain damage and death. Physicians should consider cervical spine disease, such as diffuse skeletal hyperostosis as an uncommon cause of recurrent aspiration pneumonia.
Aged
;
Bays
;
Decompression, Surgical
;
Deglutition
;
Esophagus
;
Gastrostomy
;
Humans
;
Hyperostosis
;
Hypoxia, Brain
;
Intensive Care Units
;
Neck Pain
;
Osteophyte*
;
Pneumonia
;
Pneumonia, Aspiration*
;
Shock, Septic
;
Spine
;
Vomiting
2.A Case of Exfoliative Dermatitis Induced by Phototherapy Secondary to Pustular Psoriasis
Su Jung PARK ; Guk Jin JEONG ; Jun Ki HONG ; Seong Jun SEO
Korean Journal of Dermatology 2019;57(9):556-557
No abstract available.
Dermatitis, Exfoliative
;
Phototherapy
;
Psoriasis
3.Successful desensitization for treatment of an exfoliative dermatitis to allopurinol.
Jung Won PARK ; Chein Soo HONG ; Yeong Yeon YUN ; Cheol Woo KIM ; Jung Sun KIM ; Won Chung JUNG ; Jung Yeop PARK ; Young Jun CHO ; Ae Jung HUH
Journal of Asthma, Allergy and Clinical Immunology 1999;19(6):980-984
Allopurinol is widely used for chronic tophaceous gout as a uric acid lowering agent. Hypersensitivity to allopurinol occurrs in about 10% of patients, which limits the usage of allopurinol. The successful oral and intravenous desensitization of allopurinol has been reported worldwide since 1976. We recently experienced a 51-year-old male patient with gouty arthritis and hyperuricemia, who had previously experienced skin rash after allopurinol treatment. When allopurinol was retried, erythematous and foliative skin rash developed on entire body. Because allopurinol was essential in controlling hyperuricemia, the oral desensitization of allopurinol was tried. We report successful rapid oral allopurinol desensitization in the patient with chronic tophaceous gout, who exhibited exfoliative dermatitis as allopurinol hypersensitivity.
Allopurinol*
;
Arthritis, Gouty
;
Dermatitis, Exfoliative*
;
Exanthema
;
Gout
;
Humans
;
Hypersensitivity
;
Hyperuricemia
;
Male
;
Middle Aged
;
Uric Acid
4.Association Analyses of beta3AR Trp64Arg and UCP-2 -866G/A Polymorphisms with Body Mass Index in Korean.
Hong Soo JUNG ; Joo Hyun LEE ; Jun SAKONG ; Sung Wook BAE ; Jung Hye KIM ; Jae Ryong KIM
Yeungnam University Journal of Medicine 2007;24(2):252-261
BACKGROUND: Obesity is the most common nutritional disorder in Western society as well as in Korea. Obesity results from a combination of genetic, environmental, and behavioral factors. MATERIALS AND METHODS: In an attempt to investigate the association of obesity with its candidate genes, beta3 adrenergic receptor (beta3AR) and uncoupling protein 2 (UCP2), we analyzed polymorphisms of beta3AR Trp64Arg and UCP2 -866G/A by PCR-RFLP analysis and the obesity-related phenotypes, including body mass index (BMI), fasting glucose concentration, and plasma lipid profiles in 750 subjects. RESULTS: The Trp64Arg polymorphism in the beta3AR gene was not statistically associated with the BMI. The UCP2 -866G/A polymorphism was significantly higher in obese than in non-obese subjects (P<0.05). However, the UCP2 -866A/A polymorphism was higher in the non-obese subjects. CONCLUSION: These results suggest that the UCP2 -866G/A polymorphism might be more useful for the prediction of obesity and obesity-associated diseases in Korean patients than the beta3AR Trp64Arg polymorphism.
Body Mass Index*
;
Child
;
Fasting
;
Glucose
;
Humans
;
Korea
;
Nutrition Disorders
;
Obesity
;
Phenotype
;
Plasma
;
Receptors, Adrenergic
5.Mother-Adolescent Discrepancies in Reporting Sleep Disturbances: Effects of Diagnosis and Mother’s Occupation
Eun Jung CHA ; Yeon Jung LEE ; Hong Jun JEON
Journal of Korean Medical Science 2022;37(6):e46-
Background:
Sleep disturbances are common in children and adolescents. However, they are rarely diagnosed and treated because parents, who often report the symptoms, may fail to notice the problems. Factors that can affect parent-child discrepancy include child’s diagnosis, parent’s occupation, and child’s sex. The current study retrospectively analyzed the effect of these factors on parent-child discrepancies of sleep disturbance scores.
Methods:
Data for sleep-related items in Youth Self-Report (YSR) and Child Behavior Checklist (CBCL) from 2014 to 2020 August in South Korea were collected from psychiatric outpatient clinics at Konkuk University Medical Center and Soonchunhyang University Hospital.
Results:
A three-way analysis of variance revealed main effect of diagnosis type and interaction between diagnosis type and mother’s occupation. Discrepancies were greater for mood and anxiety disorders compared to conduct-related disorder. Interaction effect revealed greater discrepancies in mood disorders for reports completed by working mothers compared to homemaker mothers.
Conclusion
The results of this study emphasize the need to explore with caution the selfreported sleep disturbances in adolescents, especially in those with mood disorders. The results also suggest that mother’s occupation should be taken into account when evaluating sleep reports of parents and adolescents.
6.Successful Endoscopic Resection of a Rectal Gastrointestinal Stromal Tumor Larger Than 5 cm
Seong Jung KIM ; Yun JUNG ; Ran HONG ; Jun LEE
The Korean Journal of Gastroenterology 2021;78(4):235-239
Preoperative imatinib treatment for rectal gastrointestinal stromal tumors (GISTs) has been reported to reduce the tumor size and help preserve the anal sphincter function. On the other hand, preoperative imatinib may prevent an accurate assessment of the recurrent risk. The endoscopic resection of rectal GIST is rarely reported because of challenges that include securing the visual field and avoiding perforation. This paper reports a case in which a 5.5×4.0 cm sized rectal GIST was treated effectively by an endoscopic submucosal dissection (ESD) without preoperative imatinib. To date, the patient had no tumor recurrence or complications and is receiving adjuvant imatinib treatment. This case shows that ESD may be a good treatment option to preserve the anus in rectal GIST treatment.
7.A Case of laugier-Hunziker syndrome.
Jin Kyung HONG ; So Hee JUNG ; Dong Won LEE ; Jun Young LEE ; Baik Kee CHO
Korean Journal of Dermatology 1999;37(1):113-115
The Laugier-Hunziker syndrome is a rare syndrome characterized by macular hyperpigmentation of the lips and buccal mucosa associated with melanonychia. Onset is usually in adult life and no consistent systemic associations have been reported. Here we report a 39-year-old wonam with a longitudinal pigmented band on a finger and pigmented macules on the lip. We suggest that this is the first report in Korea and the syndrome is presumably more common than recognized.
Adult
;
Fingers
;
Humans
;
Hyperpigmentation
;
Korea
;
Lip
;
Mouth Mucosa
8.Visual Motor Integration Abilities of Children with Learning Disorders.
Chang Jun COE ; Young Hyuk LEE ; Jung Keun KIM ; Ho Taek KIM ; Chang Ho HONG
Journal of the Korean Pediatric Society 1988;31(3):339-347
No abstract available.
Child*
;
Humans
;
Learning Disorders*
;
Learning*
9.Clinical Course of IgA Nephropathy in Children.
Ihn Hee HONG ; Jun Hwa LEE ; Cheol Woo KO ; Ja Hoon KOO ; Jung Sik KWAK
Journal of the Korean Society of Pediatric Nephrology 1999;3(2):153-160
A statistical analysis of the diagnostic value for 244 aspiration biopsy cytology(ABC) among a total 1,043 cases from various sites was performed. ABC, using diagnostic terminology similar to that of a surgical pathology reports, was compared to the final tissue diagnosis. For the entire series, a sensitivity of 91.8%, a specificity of 99.3%, a positive predictive value of 98.9%, a negative predictive value of 94.8%, and an efficacy of the test of 96.3% were shown. There were 8 false negative and 1 false positive diagnosis. The diagnostic accuracy was 89.8%. Those results indicate that the ABC is a considerably highly accurate procedure that should be routinely employed.
Biopsy, Needle
;
Child*
;
Diagnosis
;
Glomerulonephritis, IGA*
;
Humans
;
Immunoglobulin A*
;
Intranuclear Inclusion Bodies
;
Meningioma
;
Pathology, Surgical
;
Sensitivity and Specificity
10.Catecholamine-Induced Cardiomyopathy associated with Neuroblastoma and Treated with Extracorporeal Membrane Oxygenation as a Bridge to Recovery.
Junggu YI ; Si Oh KIM ; Jun mo PARK ; Sung Hye BYUN ; Hoon JUNG ; Seong Wook HONG
Korean Journal of Critical Care Medicine 2015;30(4):299-302
Catecholamine-induced cardiomyopathy associated with neuroblastoma is rarely reported. We report a case of catecholamine-induced cardiomyopathy associated with neuroblastoma in a 33-month-old female that was treated with extracorporeal membrane oxygenation (ECMO). She was tentatively diagnosed with acute myocarditis and presented with hypertension. Because of rapid patient deterioration despite pharmacological treatments, ECMO was applied. ECMO can be helpful in cases of catecholamine-induced cardiomyopathy associated with neuroblastoma.
Cardiomyopathies*
;
Catecholamines
;
Child, Preschool
;
Extracorporeal Membrane Oxygenation*
;
Female
;
Humans
;
Hypertension
;
Myocarditis
;
Neuroblastoma*