2.Prevention of chemotherapy-induced oral mucositis in patients with acute leukemia by the two oral care protocols : the comparisons of Sodium Bicarbonate-normal saline gargling and Chlorhexidine gargling.
Yeon Hee KIM ; Myung Hee JUN ; Jin Sun CHOI
Journal of Korean Academy of Adult Nursing 1997;9(1):98-111
Oral mucositis continues to be a major complaint of patients who have chemotherapy for the acute leukemia. An innovative and inexpensive remedy which produces favorable results for those afficted is not yet introduced. So we tried to develop two oral care protocols for reducing the level of oral mucositis during cytotoxic therapy through literature review and our clinical experience. The one is sodium bicarbonate-normal saline gargling, and the other consists of chlorhexidine gargling. This quasi-experimental study was performed to compare the efficacy of these two different oral care protocols. Twenty subjects were assigned to one of the two specific diagnosis of leukemia, aim of the chemotherapy. The Oral Assessment Guide(OAG), the Beck's perception of oral comfort, WHO Grading system fot mucositis and the discomfort of oral gargling solution were used to assess oral status and subject's oral discomfort during chemotherapy. Each subjects were observed daily from the start of the chemotherapy until Absolute Neutrophil Count(ANC) reached 1,000. It continued about 2-4 weeks. The data analyzed by Mann-Whittney U test and ANCOVA. The result was follows as: The patient who used sodium bicarbonate-normal saline gargling showed significantly higher mean score of the discomfort of oral gargling solution than chlorhexidine gargling. The other scores were not significantly different between two groups. However the subjects using the sodium bicarbonate-normal saline gargling showed a lower level of oral mucositis. We concluded that oral using sodium bicarbonate-normal saline gargling was between to reduce the level of oral mucositis during chemotherapy and nursing assessments of the oral cavity seemed to promote patient's compliance with the oral care regimen.
Chlorhexidine*
;
Compliance
;
Diagnosis
;
Drug Therapy
;
Humans
;
Leukemia*
;
Mouth
;
Mucositis
;
Neutrophils
;
Nursing Assessment
;
Sodium*
;
Stomatitis*
3.Polyethylene Glycol (PEG-3350, Colyte) Poisoning due to Intra-Peritoneal Leakage in an Elderly Patient.
Jae Hee CHUNG ; Seok Chan KIM ; Jun Gi KIM
Korean Journal of Critical Care Medicine 2015;30(1):56-60
Polyethylene glycol (PEG)-3350 is the most frequently used lavage solution for bowel cleansing prior to colonoscopy or elective surgery because its large molecular weight means that it is poorly absorbed. However, if it leaks into the peritoneal cavity, complications may arise. Few published studies have assessed the absorption, distribution, metabolism and excretion of PEG. Moreover, no published clinical data regarding complications due to the intra-peritoneal leakage of PEG-3350 could be found. We report on an elderly patient who developed the poisoning caused by leaking of PEG-3350 during bowel preparation. It resulted in severe metabolic acidosis, hypernatremia, hyperosmolality and a high anion gap, but it was effectively treated with early continuous renal replacement therapy after surgery.
Absorption
;
Acid-Base Equilibrium
;
Acidosis
;
Aged*
;
Colonoscopy
;
Humans
;
Hypernatremia
;
Metabolism
;
Molecular Weight
;
Peritoneal Cavity
;
Poisoning*
;
Polyethylene Glycols*
;
Renal Replacement Therapy
;
Therapeutic Irrigation
4.Pseudohypoparathyroidism and Peudopseudohypoparathyroidism in a Family.
Young Cherl LEE ; Duk Hee KIM ; Chang Jun COE
Journal of the Korean Pediatric Society 1984;27(11):1128-1134
No abstract available.
Humans
;
Pseudohypoparathyroidism*
5.Comparison of Laparosopic Varicocelectomy with Subinguinal Varicocelectomy.
Hee Cheol YOON ; Jun RHO ; Chul Sung KIM
Korean Journal of Urology 2000;41(11):1403-1408
No abstract available.
6.Perforation of idiopathic small bowel ulceration after blunt abdominal trauma in a child: a Case Report.
Yeon Jun JEONG ; Hee Chul YU ; Jae Chun KIM
Journal of the Korean Association of Pediatric Surgeons 1999;5(2):141-145
Idiopathic small bowel ulceration occurring beyond the duodenum is rare, and less than 5% of all the reported cases have occurred in children. In most of the cases, single ulcer of unknown cause is observed in jejunum or ileum. The diagnosis is difficult and usually made at the time of surgical exploration for the complications, such as perforation, hemorrhage or obstruction. We experienced a case of perforation of idiopathic ileal ulceration due to blunt abdominal trauma in a 11-year-old boy. The ileal segment including the lesion was resected and the pathologic findings were compatible with idiopathic small bowel ulceration. The clinical and pathological aspects are discussed, and the literatures were reviewed.
Child*
;
Diagnosis
;
Duodenum
;
Hemorrhage
;
Humans
;
Ileum
;
Jejunum
;
Male
;
Ulcer*
7.Clinical Observation of Congenital Urinary Tract Anomalies.
Sun Jun KIM ; Dae Yeol LEE ; Soo Hee CHANG
Journal of the Korean Society of Pediatric Nephrology 1997;1(1):67-72
We present the cytologic features of a case of solid and papillary neoplasm of the pancreas. Cytologically, the tumor was composed of a monotonous population of polygonal cells containing eccentrically located round nuclei with one or two distinct small nucleoli and a finely stippled chromatin pattern. The tumor cells were similar to those of the islet cell tumor and showed isolated loosely aggregated and solid sheets or large cell clumps. The large cell clumps revealed a branching papillary structure containing fibrovascular central core, which is characteristic histologic feature of solid and papillary neoplasm of the pancreas. This case was confirmed by tissue examination including histochemical, immunohistochemical and electron microscopical studies. Ultrastructurally, the tumor cells contained a few membrane-bound electron dense granules.
Adenoma, Islet Cell
;
Chromatin
;
Pancreas
;
Urinary Tract*
8.A Clinical Investigation on 10 Patients of Tuberous Sclerosis.
Hee Jung CHUNG ; Myung Jin KIM ; Chang Jun COE
Journal of the Korean Pediatric Society 1983;26(4):373-379
No abstract available.
Humans
;
Tuberous Sclerosis*
9.A Family of Benign Familial Hematuria.
Ran NAMKUNG ; Jun Hee SUL ; Pyung Kil KIM ; In Joon CHOI
Journal of the Korean Pediatric Society 1981;24(4):358-366
No abstract available.
Hematuria*
;
Humans
10.A comparative study of therapeutic effect of aspirin alone and intravenous gammaglobulin plus aspirin in Kawasaki disease.
Young Hee HWANG ; Jin Gon JUN ; Chu Dong KIM
Yeungnam University Journal of Medicine 1992;9(1):44-53
We compared the efficacy of each modality of treatment group in reducing the frequency of coronary artery abnormalities and change of clinical courses in children with Kawasaki disease in the children of 81 cases who were admitted in pediatric department of Yeungnam University Hospital from September 1985 to August 1990. Group A (37 cases)-aspirin alone, Group B (44 cases)-intravenous gammaglobulin (400 mmg/kg/day) for 5 consecutive days, plus aspirin. We studied the frequency of echocardiographic abnormalities, the duration of fever, and changes in the total white blood cell counts, platelet counts, ESR and CRP value at 1, 2 and 3 weeks of the illness and compared the results between the two groups. The results were as follows. 1) There was no significant intergroup difference in age and sex ratio. 2)The duration of the febrile period after the initiation of the therapy was significant shorter in group B (2.5±1.2days) than in group A: (5.2±3.5 days) (p<0.01). 3) No significant difference was noticed in the WBC and platelet counts in two groups as measured at admission day, 1 and 2 weeks of the illness, however, at 3weeks of illness significant difference was noted. 4) The CRP values measured at 1,2 and 3 weeks after treatment were significantly lower in group B (2.42±1.8, 2.00±1.2, 1.16±1.0) than in group A (7.22±5.3, 5.25±3.9, 1.85±1.2) respectively (p<0.01). 5) In 2D-Echocardiogram, coronary artery dilatation was more frequent in Group A than in Group B at 6month of illness (p<0.01). In conclusion, intravenous gammaglobulin therapy was effective in the shortening of the duration of fever and in the anti-inflammatory action and somewhat effective in prevention of coronary artery aneurysm.
Aneurysm
;
Aspirin*
;
Child
;
Coronary Vessels
;
Dilatation
;
Echocardiography
;
Fever
;
Humans
;
Leukocyte Count
;
Mucocutaneous Lymph Node Syndrome*
;
Platelet Count
;
Sex Ratio