1.Recurrent Aspiration Pneumonia due to Anterior Cervical Osteophyte.
Jae Jun LEE ; Ji Young HONG ; Jun Han JUNG ; Jun Hyeok YANG ; Jun Young SOHN
Korean Journal of Critical Care Medicine 2017;32(1):74-78
A 74-year-old man presented with recurrent vomiting and aspiration pneumonia in the left lower lobe. He entered the intensive care unit to manage the pneumonia and septic shock. Although a percutaneous endoscopic gastrostomy tube was implanted for recurrent vomiting, vomiting and aspiration recurred frequently during admission. Subsequently, he complained of neck pain when in an upright position. A videofluoroscopic swallowing study showed compression of the esophagus by cervical osteophytes and tracheal aspiration caused by an abnormality at the laryngeal inlet. Cervical spine X-rays and computed tomography showed anterior cervical osteophytes at the C3-6 levels. Surgical decompression was scheduled, but was cancelled due to his frailty. Unfortunately, further recurrent vomiting and aspiration resulted in respiratory arrest leading to hypoxic brain damage and death. Physicians should consider cervical spine disease, such as diffuse skeletal hyperostosis as an uncommon cause of recurrent aspiration pneumonia.
Aged
;
Bays
;
Decompression, Surgical
;
Deglutition
;
Esophagus
;
Gastrostomy
;
Humans
;
Hyperostosis
;
Hypoxia, Brain
;
Intensive Care Units
;
Neck Pain
;
Osteophyte*
;
Pneumonia
;
Pneumonia, Aspiration*
;
Shock, Septic
;
Spine
;
Vomiting
2.A case of sparganosis infesting in the labia majora.
Kyeong Earn SONG ; Jong Il JUNG ; Sae Jun HAN
Korean Journal of Obstetrics and Gynecology 1991;34(12):1646-1660
No abstract available.
Sparganosis*
3.Arthroscopic Management of Osteoarthritic Knee
Suk Kee TAE ; Yung Bok JUNG ; Han Jun LEE
The Journal of the Korean Orthopaedic Association 1994;29(7):1781-1785
There are many options for the management of osteoarthritis of the knee joint. Recently, arthroscopic surgery has been added to the armamentorium of the treatment modalities in osteoarthritis of the knee which does not respond to conservative treatment. Among 74 arthroscopic pocedures(including partial menisectomy, removal of loose bodies, synovectomy, cartilage drilling and simple lavage) done for osteoarthritis of the knee, 68 patients studied at average 3.1 years after procedure and the results were as follows 1. Seventy-one percent of patients had at least 2.5 years or more relief of pain and symptoms. 2. Fifty-six percent were still good at follow-up of 3.1 years. 3. The best result were obtained after removal of loose bodies and resection of unstable flap tear of a meniscus in association with mild osteoarthritis. 4. The poor result were obtained in patients with severe degenerative changes of both femoral condyle, 5. The results were much better in the normally aligned knee compared with valgus knee.
Arthroscopy
;
Cartilage
;
Follow-Up Studies
;
Humans
;
Knee Joint
;
Knee
;
Osteoarthritis
;
Tears
4.A case of immunologic trombocytopenic purpura in pregnancy.
Yong Eun LEE ; Seung Jin OH ; Ha Jong JANG ; Jung Sik CHO ; Huk JUNG ; Jong Il JUNG ; Sae Jun HAN
Korean Journal of Obstetrics and Gynecology 1991;34(10):1463-1469
No abstract available.
Pregnancy*
;
Purpura*
5.A Clinical Study on the Ovarian Tumors in Pregnancy.
Yong Gul KIM ; Tae Jung KIM ; Hyun Jung LIM ; Sang Joon CHOI ; Chang Hun SONG ; Sei Jun HAN ; Hyuk JUNG
Korean Journal of Perinatology 2001;12(1):35-43
No abstract available.
Pregnancy*
6.The proteomic landscape shows oncologic relevance in cystitis glandularis
Jun Yong KIM ; Dohyun HAN ; Hyeyoon KIM ; Minsun JUNG ; Han Suk RYU
Journal of Pathology and Translational Medicine 2023;57(1):67-74
Background:
The relationship between cystitis glandularis (CG) and bladder malignancy remains unclear.
Methods:
We identified the oncologic significance of CG at the molecular level using liquid chromatography-tandem mass spectrometry-based proteomic analysis of 10 CG, 12 urothelial carcinoma (UC), and nine normal urothelium (NU) specimens. Differentially expressed proteins (DEPs) were identified based on an analysis of variance false discovery rate < 0.05, and their functional enrichment was analyzed using a network model, Gene Set Enrichment Analysis, and Gene Ontology annotation.
Results:
We identified 9,890 proteins across all samples and 1,139 DEPs among the three entities. A substantial number of DEPs overlapped in CG/NU, distinct from UC. Interestingly, we found that a subset of DEP clusters (n = 53, 5%) was differentially expressed in NU but similarly between CG and UC. This “UC-like signature” was enriched for reactive oxygen species (ROS) and energy metabolism, growth and DNA repair, transport, motility, epithelial-mesenchymal transition, and cell survival. Using the top 10 shortlisted DEPs, including SOD2, PRKCD, CYCS, and HCLS1, we identified functional elements related to ROS metabolism, development, and transport using network analysis. The abundance of these four molecules in UC/CG than in NU was consistent with the oncologic functions in CG.
Conclusions
Using a proteomic approach, we identified a predominantly non-neoplastic landscape of CG, which was closer to NU than to UC. We also confirmed a small subset of common DEPs in UC and CG, suggesting that altered ROS metabolism might imply potential cancerous risks in CG.
7.HLA-DR genotyping from sperm by double PCR.
Hoon HAN ; Byung Uk LIM ; Yeun Jun CHUNG ; Jung Bin LEE
Korean Journal of Immunology 1991;13(1):89-98
No abstract available.
HLA-DR Antigens*
;
Polymerase Chain Reaction*
;
Spermatozoa*
8.A Case of Ki-1 Positive Type B Lymphomatoid Papulosis.
Min Ja JUNG ; Sang Jun LEE ; Yoon Whoa CHO ; Jee Yoon HAN ; Kye Yong SONG
Korean Journal of Dermatology 1998;36(3):540-544
The monoclonal antibody Ki-1(CD30) was first described in 1982 and was reported to react selectively with Reed-Sternberg cells in Hodgkins disease, highly activated B and T cells and large cell lymphomas of both T-and B-cell origin. Lymphomatoid papulosis(LyP) is characterized by recurrent erythematous papules or nodules that undergo spontaneous healing with hyperpigmentation and scarring. Histologically, two major types of LyP can be distinguished: type A is characterized by the presence of variable numbers of Ki-1+ large, atypical lymphocytes with some Reed-Sternberg like cells and type B is characterized by Ki-1- atypical cerebriform mononuclear cells similar to those in mycosis fungoides. We report a case of Ki-1+ lymphomatoid papulosis which was histopathologically recognized as a type B lesion but represented a Ki-1 positive reaction.
B-Lymphocytes
;
Cicatrix
;
Hodgkin Disease
;
Hyperpigmentation
;
Lymphocytes
;
Lymphoma
;
Lymphomatoid Papulosis*
;
Mycosis Fungoides
;
Reed-Sternberg Cells
;
T-Lymphocytes
9.A Case of Kaposi's Sarcoma with Disseminated Papules on both Lower Legs.
Sang Jun LEE ; Min Ja JUNG ; Yoon Whoa CHO ; Jee Yoon HAN ; Kye Yong SONG
Korean Journal of Dermatology 1998;36(2):300-303
Kaposis sarcoma is a multicentric neoplastic vascular tumor involving the skin or internal organs. We report a case of classic Kaposis sarcoma in a 69-year-old male who had positive serum cytomegalovirus antibodies and disseminated multiple erythematous to purplish colored confluent papules and edema on both lower legs. The histopathological finding showed abnormally proliferated and dilated vessels, vascular spaces, spindle cells, and extravasated erythrocytes. He was treated with radiotherapy, but died due to ventricular tachycardia.
Aged
;
Antibodies
;
Cytomegalovirus
;
Edema
;
Erythrocytes
;
Humans
;
Leg*
;
Male
;
Radiotherapy
;
Sarcoma, Kaposi*
;
Skin
;
Tachycardia, Ventricular
10.Bilateral Coronary Artery-Right Ventricular Fistula in Newborn: Associated with Atrial Septal Defect.
Jo Won JUNG ; Jong Kyun LEE ; Jun Hee SUL ; Sung Kyu LEE ; Dong Gwan HAN
Korean Circulation Journal 1991;21(6):1259-1264
Bilateral coronary artery fistula is very uncommon congenital anomaly which occupy small percentage of all congenital coronary artery fistula. About 20% of the cases associated with additional congenital heart disease. And it may cause congestive heart failure, especially severely in neonate. We experienced a case of neonate who was 1 day-old-male with bilateral coronary artery-right ventricular fistula associated with atrial septal defect and congestive heart failure. The Patient was admitted because dyspnea, cyanosis since birth. 2D ecgicardiogram and cardiac catheterization revealed that a fistulous communicating ; forming a large aneurysm, was noted from bilateral coronary artery emptied into the right ventricle, and there was oxygen step-up in right ventricle.
Aneurysm
;
Cardiac Catheterization
;
Cardiac Catheters
;
Coronary Vessels
;
Cyanosis
;
Dyspnea
;
Fistula*
;
Heart Defects, Congenital
;
Heart Failure
;
Heart Septal Defects, Atrial*
;
Heart Ventricles
;
Humans
;
Infant, Newborn*
;
Oxygen
;
Parturition