1.A case of localized scleroderma successfully treated with systemic corticosteroid and colchicine.
Juhendy Merlina ; Gabriel Ma. Teresita G
Journal of the Philippine Dermatological Society 2012;21(2):32-36
Localized scleroderma, otherwise known as morphea, is a rare fibrosing disorder of the skin and underlying tissues with equal prevalence in adults and children. It is a distinct and separate disease entity from sytemic sclerosis. Although the etiology and pathogenesis have not been identified, the clinical manifestations are due to the thickened collagen bundles infiltrating the entire dermis and extending into the subcutaneous fat. This condition is self-limiting and may last for 3 to 5 years. We report a case of a 45-year-old man who presented with multiple, ill-defined, warm, indurated, slightly erythematous to hyperpigmented plaques with central atrophy on both thighs and lower legs of five months' duration. He was successfully treated with colchicine and sytemic corticosteroids.
Human ; Male ; Middle Aged ; Adrenal Cortex Hormones ; Atrophy ; Colchicine ; Collagen ; Dermis ; Fibrosis ; Leg ; Prevalence ; Scleroderma, Localized ; Sclerosis ; Skin ; Subcutaneous Fat ; Thigh ; Skin And Connective Tissue Diseases